RG7345 is a humanized monoclonal antibody targeting the tau phosphoepitope pS422. Tau phosphorylated at this site is considered a pathological form that has been linked to the relocalization of tau away from microtubules and toward the somato-dendritic compartment of the neuron.
Relation | Identifier | Name |
is_a | CONSO:CONSO00307 | Tau antibody |