CM-414
A dual inhibitor of PDE5 and HDACs, chronic treatment of Tg2576 mice, a well characterized AD mouse model, showed decreased Ab and Tau phsophorylation and inhibition of GSK3B activity.
- Identifier
- CONSO00246
- Type
- chemical
- Author
- Kristian Kolpeja
https://orcid.org/0000-0001-9661-5277
References
Cross-references
- cas:4432-44-4
- inchi:InChI=1S/C8H13NO3/c1-7(8(10)11)6-9-2-4-12-5-3-9/h1-6H2,(H,10,11)
- pubchem.compound:10397232
- smiles:C=C(CN1CCOCC1)C(=O)O
Synonyms
| Synonym | Reference | Specificity |
| 2-(4-morpholinylmethyl)-2-propenoic acid | pubchem.compound:10397232 | EXACT |
| 2-(Morpholinomethyl)acrylic acid | pubchem.compound:10397232 | EXACT |
| 2-(Morpholinomethyl)propenoic acid | pubchem.compound:10397232 | EXACT |
| 2-(morpholin-4-ylmethyl)prop-2-enoic Acid | pubchem.compound:10397232 | EXACT |
| 2-MORPHOLIN-4-YLMETHYL-ACRYLIC ACID | pubchem.compound:10397232 | EXACT |
| 2-Morpholin4-ylmethyl-acrylic acid | pubchem.compound:10397232 | EXACT |
| 2-[(morpholin-4-yl)methyl]prop-2-enoic acid | pubchem.compound:10397232 | EXACT |
| 2-morpholin-4-ylmethyl-2-propenoic acid | pubchem.compound:10397232 | EXACT |
| 2-morpholin-4ylmethyl-2-propenoic acid | pubchem.compound:10397232 | EXACT |
| 4-Morpholinepropanoicacid, a-methylene- | pubchem.compound:10397232 | EXACT |
| 4432-44-4 | pubchem.compound:10397232 | EXACT |
| 4868AH | pubchem.compound:10397232 | EXACT |
| A826542 | pubchem.compound:10397232 | EXACT |
| AB0085720 | pubchem.compound:10397232 | EXACT |
| AB1552 | pubchem.compound:10397232 | EXACT |
| AJ-96850 | pubchem.compound:10397232 | EXACT |
| AKOS010054622 | pubchem.compound:10397232 | EXACT |
| CM-414 | pubchem.compound:10397232 | EXACT |
| CTK4I8112 | pubchem.compound:10397232 | EXACT |
| DB-070534 | pubchem.compound:10397232 | EXACT |
| DTXSID30439182 | pubchem.compound:10397232 | EXACT |
| F9995-2550 | pubchem.compound:10397232 | EXACT |
| FT-0718529 | pubchem.compound:10397232 | EXACT |
| IGZSSKAOSOCVPH-UHFFFAOYSA-N | pubchem.compound:10397232 | EXACT |
| K-8942 | pubchem.compound:10397232 | EXACT |
| KB-106928 | pubchem.compound:10397232 | EXACT |
| MCULE-2720405682 | pubchem.compound:10397232 | EXACT |
| MFCD06208438 | pubchem.compound:10397232 | EXACT |
| MolPort-019-997-392 | pubchem.compound:10397232 | EXACT |
| SCHEMBL793684 | pubchem.compound:10397232 | EXACT |
| ZINC38760485 | pubchem.compound:10397232 | EXACT |