PrP106-126
Prion protein fragment 106-126. This peptide increases membrane microviscosity, intracellular Ca2+ concentration and cell migration in circulating leucocytes, and oxygen production in monocytes and neutrophils. It also induces apoptotic cell death and impairment of L-type voltage-sensitive calcium channel activity in the GH3 cell lines. PrP (106–126) stimulates leucocyte migration in a dose-dependent manner. Inhibits tau phosphorylaton at Ser262. Seq = KTNMKHMAGAAAAGAVVGGLG
- Identifier
- CONSO00220
- Type
- protein fragment
- Author
- Kristian Kolpeja
https://orcid.org/0000-0001-9661-5277