Curation of Neurodegeneration in BEL (CONIB) 0.0.8

Mechanistic knowledge surrounding several neurodegenerative diseases, with specific focus on protein aggregation, nicotinic receptor signalling, proteostasis, and other mechanisms.

Authors
Charles Tapley Hoyt, Daniel Domingo-Fernández, Esther Wollert, Sandra Spalek, Rana Al Disi, Lingling Xu, Kristian Kolpeja, Yojana Gadiya, Trusha Adeshara, Stephan Gebel, Sepehr Golriz
Contact
cthoyt@gmail.com
License
CC0 1.0 Universal
Copyright
Copyright © 2019 Fraunhofer SCAI, All rights reserved.

Summary

Name
Curation of Neurodegeneration in BEL (CONIB)
Version
0.0.8
Authors
Charles Tapley Hoyt, Daniel Domingo-Fernández, Esther Wollert, Sandra Spalek, Rana Al Disi, Lingling Xu, Kristian Kolpeja, Yojana Gadiya, Trusha Adeshara, Stephan Gebel, Sepehr Golriz
Number of Nodes
8976
Number of Namespaces
37
Number of Edges
32939
Number of Annotations
54
Number of Citations
568
Number of Authors
3839
Network Density
4.09E-04
Number of Components
30
Number of Warnings
55

Nodes

Each node in a BEL graph is assigned a type. Most nodes are then identified with a namespace:identifier pair, or a definition based on other nodes as in the case of complexes, composites, and chemical reactions.

Edges

Topology

Bibliometrics

Statements

Reference BEL
pubmed:30046111 tloc(a(CHEBI:amyloid-beta), fromLoc(MESH:Blood), toLoc(MESH:"Cerebrospinal Fluid")) regulates deg(a(CHEBI:amyloid-beta))
pubmed:27299292 a(CHEBI:amyloid-beta, loc(MESH:Astrocytes)) increases deg(a(CHEBI:amyloid-beta))
pubmed:29626319 tloc(a(CHEBI:amyloid-beta), fromLoc(MESH:Brain), toLoc(MESH:Blood)) decreases a(CHEBI:amyloid-beta)
pubmed:30046111 a(CHEBI:amyloid-beta) negativeCorrelation act(a(MESH:"Lymphatic Vessels"))
pubmed:30046111 a(CHEBI:amyloid-beta) positiveCorrelation path(MESH:"Alzheimer Disease")
pubmed:30046111 a(CHEBI:amyloid-beta) positiveCorrelation path(MESH:"Alzheimer Disease")
pubmed:30046111 a(CHEBI:amyloid-beta) positiveCorrelation path(MESH:"Alzheimer Disease")
pubmed:29196815 a(CHEBI:amyloid-beta) positiveCorrelation path(MESH:"Alzheimer Disease")
pubmed:29196815 a(CHEBI:amyloid-beta) positiveCorrelation path(MESH:"Alzheimer Disease")
pubmed:23556446 a(CHEBI:amyloid-beta) increases path(MESH:"Alzheimer Disease")
pubmed:19293145 a(CHEBI:amyloid-beta) increases path(MESH:"Alzheimer Disease")
pubmed:19293145 tloc(a(CHEBI:amyloid-beta), fromLoc(go:0005622 ! intracellular), toLoc(go:0005615 ! "extracellular space")) association path(MESH:"Alzheimer Disease")
pubmed:19293145 a(CHEBI:amyloid-beta) association path(MESH:"Alzheimer Disease")
pubmed:25514383 a(CHEBI:amyloid-beta) positiveCorrelation path(MESH:"Alzheimer Disease")
pubmed:11230871 a(CHEBI:amyloid-beta) increases path(MESH:"Alzheimer Disease")
pubmed:14556719 a(CHEBI:amyloid-beta) association path(MESH:"Alzheimer Disease")
pubmed:29980653 a(CHEBI:amyloid-beta) positiveCorrelation path(MESH:"Alzheimer Disease")
pubmed:30046111 a(CHEBI:amyloid-beta) association a(MESH:Macrophages)
pubmed:30663117 a(CHEBI:amyloid-beta) increases p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation"))
pubmed:19293145 a(CHEBI:amyloid-beta) increases p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation"))
pubmed:26813123 a(CHEBI:amyloid-beta) regulates p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation"))
pubmed:28745240 a(CHEBI:amyloid-beta) decreases bp(GO:"calcium ion homeostasis")
pubmed:28745240 a(CHEBI:amyloid-beta) association bp(MESH:"Oxidative Stress")
pubmed:28745240 a(CHEBI:amyloid-beta) increases bp(MESH:"Oxidative Stress")
pubmed:28745240 a(CHEBI:amyloid-beta) increases bp(GO:"apoptotic process")
pubmed:28745240 a(CHEBI:amyloid-beta) increases bp(GO:"apoptotic process")
pubmed:27288790 a(CHEBI:amyloid-beta) increases bp(GO:"apoptotic process")
pubmed:19293145 act(a(CHEBI:amyloid-beta)) increases bp(GO:"apoptotic process")
pubmed:28745240 a(CHEBI:amyloid-beta) increases bp(GO:"JNK cascade")
pubmed:28745240 a(CHEBI:amyloid-beta) increases bp(GO:"Fas signaling pathway")
pubmed:28745240 a(CHEBI:amyloid-beta) increases act(complex(GO:"NF-kappaB complex"))
pubmed:28745240 a(CHEBI:amyloid-beta) increases act(complex(GO:"NF-kappaB complex"))
pubmed:28745240 a(CHEBI:amyloid-beta) increases complex(GO:"NF-kappaB complex")
pubmed:28745240 a(CHEBI:amyloid-beta) increases act(complex(GO:"NF-kappaB complex"))
pubmed:28745240 a(CHEBI:amyloid-beta) increases act(complex(GO:"NF-kappaB complex"))
pubmed:25652642 a(CHEBI:amyloid-beta) increases act(complex(GO:"NF-kappaB complex"))
pubmed:25652642 a(CHEBI:amyloid-beta) positiveCorrelation act(complex(GO:"NF-kappaB complex"))
pubmed:25652642 a(CHEBI:amyloid-beta) decreases act(complex(GO:"NF-kappaB complex"))
pubmed:25652642 a(CHEBI:amyloid-beta) increases act(complex(GO:"NF-kappaB complex"))
pubmed:28745240 a(CHEBI:amyloid-beta) decreases p(HGNC:BCL2L1)
pubmed:28745240 a(CHEBI:amyloid-beta) decreases tloc(a(PUBCHEM:16057918), fromLoc(go:0005622 ! intracellular), toLoc(go:0005615 ! "extracellular space"))
pubmed:28745240 a(CHEBI:amyloid-beta) increases complex(a(GO:"membrane attack complex"), p(HGNC:C5))
pubmed:28745240 a(CHEBI:amyloid-beta) increases p(HGNC:TNF)
pubmed:29179999 a(CHEBI:amyloid-beta) increases tloc(p(HGNC:TNF), fromLoc(go:0005622 ! intracellular), toLoc(go:0005615 ! "extracellular space"))
pubmed:28019679 a(CHEBI:amyloid-beta) increases tloc(p(HGNC:TNF), fromLoc(go:0005622 ! intracellular), toLoc(go:0005615 ! "extracellular space"))
pubmed:28745240 a(CHEBI:amyloid-beta) increases p(HGNC:APP)
pubmed:18930136 a(CHEBI:amyloid-beta) association deg(p(HGNC:APP))
pubmed:28745240 a(CHEBI:amyloid-beta) increases act(complex(GO:"calcium- and calmodulin-dependent protein kinase complex"))
pubmed:28745240 a(CHEBI:amyloid-beta) regulates act(p(FPLX:PKC))
pubmed:28745240 a(CHEBI:amyloid-beta) regulates bp(CONSO:"PI3K-Akt signaling pathway")
pubmed:28745240 a(CHEBI:amyloid-beta) increases path(CONSO:neurotoxicity)
pubmed:25652642 a(CHEBI:amyloid-beta) increases path(CONSO:neurotoxicity)
pubmed:19293145 a(CHEBI:amyloid-beta) increases path(CONSO:neurotoxicity)
pubmed:19293145 act(a(CHEBI:amyloid-beta)) increases path(CONSO:neurotoxicity)
pubmed:19293145 act(a(CHEBI:amyloid-beta)) increases path(CONSO:neurotoxicity)
pubmed:19293145 a(CHEBI:amyloid-beta) increases path(CONSO:neurotoxicity)
pubmed:19293145 act(a(CHEBI:amyloid-beta)) increases path(CONSO:neurotoxicity)
pubmed:24590577 a(CHEBI:amyloid-beta) increases path(CONSO:neurotoxicity)
pubmed:21882945 a(CHEBI:amyloid-beta) increases path(CONSO:neurotoxicity)
pubmed:28745240 a(CHEBI:amyloid-beta) increases a(CHEBI:"calcium(2+)")
pubmed:30688256 a(CHEBI:amyloid-beta, loc(MESH:Mitochondria)) increases a(CHEBI:"calcium(2+)")
pubmed:28745240 a(CHEBI:amyloid-beta) increases act(a(MESH:Microglia))
pubmed:29179999 a(CHEBI:amyloid-beta) increases bp(GO:"glial cell activation")
pubmed:29179999 a(CHEBI:amyloid-beta) increases bp(GO:"inflammatory response")
pubmed:16566606 a(CHEBI:amyloid-beta) increases bp(GO:"inflammatory response")
pubmed:29179999 a(CHEBI:amyloid-beta) increases tloc(p(HGNC:IL1B), fromLoc(go:0005622 ! intracellular), toLoc(go:0005615 ! "extracellular space"))
pubmed:29179999 a(CHEBI:amyloid-beta) increases tloc(p(HGNC:IL6), fromLoc(go:0005622 ! intracellular), toLoc(go:0005615 ! "extracellular space"))
pubmed:29179999 a(CHEBI:amyloid-beta) increases act(p(FPLX:NFkappaB))
pubmed:27288790 a(CHEBI:amyloid-beta) increases act(p(FPLX:NFkappaB))
pubmed:26010758 a(CHEBI:amyloid-beta) increases act(p(FPLX:NFkappaB))
pubmed:27288790 a(CHEBI:amyloid-beta) increases act(p(HGNC:NFKB1))
pubmed:27288790 a(CHEBI:amyloid-beta) increases act(p(HGNC:RELA))
pubmed:25652642 a(CHEBI:amyloid-beta) increases act(p(HGNC:APOE))
pubmed:26195256 tloc(a(CHEBI:amyloid-beta), fromLoc(MESH:"Extracellular Space"), toLoc(MESH:"Cardiovascular System")) negativeCorrelation tloc(p(HGNC:APOE), fromLoc(MESH:"Extracellular Space"), toLoc(MESH:"Cardiovascular System"))
pubmed:25652642 a(CHEBI:amyloid-beta) increases bp(GO:"neuron death")
pubmed:21214928 a(CHEBI:amyloid-beta) increases bp(GO:"neuron death")
pubmed:22122372 a(CHEBI:amyloid-beta) increases bp(GO:"neuron death")
pubmed:22122372 a(CHEBI:amyloid-beta) increases bp(GO:"neuron death")
pubmed:25652642 a(CHEBI:amyloid-beta) increases r(HGNC:BAX)
pubmed:25652642 a(CHEBI:amyloid-beta) decreases r(HGNC:BCL2L1)
pubmed:25652642 a(CHEBI:amyloid-beta) increases a(MESH:"I-kappa B Proteins", loc(GO:cytoplasm))
pubmed:29844403 a(CHEBI:amyloid-beta) increases p(CONSO:"Tau aggregates")
pubmed:28500862 a(CHEBI:amyloid-beta) positiveCorrelation p(CONSO:"Tau aggregates")
pubmed:29844403 a(CHEBI:amyloid-beta) increases p(MESH:"Neurofibrillary Tangles")
pubmed:30232325 a(CHEBI:amyloid-beta) increases path(CONSO:CONSO00061)
pubmed:21214928 a(CHEBI:amyloid-beta) increases path(CONSO:CONSO00061)
pubmed:22122372 a(CHEBI:amyloid-beta) increases path(CONSO:CONSO00061)
pubmed:22122372 a(CHEBI:amyloid-beta) increases path(CONSO:CONSO00061)
pubmed:29196815 a(CHEBI:amyloid-beta) increases bp(GO:"neuron apoptotic process")
pubmed:29196815 a(CHEBI:amyloid-beta) increases complex(GO:"neurofibrillary tangle")
pubmed:29196815 a(CHEBI:amyloid-beta) increases path(MESH:Gliosis)
pubmed:29196815 a(CHEBI:amyloid-beta) increases path(MESH:"Neuroaxonal Dystrophies")
pubmed:18650430 a(CHEBI:amyloid-beta) increases bp(GO:"cell adhesion")
pubmed:21214928 a(CHEBI:amyloid-beta) increases path(MESH:"Plaque, Amyloid")
pubmed:21214928 a(CHEBI:amyloid-beta) increases path(MESH:"Plaque, Amyloid")
pubmed:21214928 a(CHEBI:amyloid-beta) increases path(CONSO:CONSO00027)
pubmed:21214928 a(CHEBI:amyloid-beta) decreases bp(GO:"regulation of synapse structure or activity")
pubmed:21214928 a(CHEBI:amyloid-beta) decreases bp(GO:"regulation of synapse structure or activity")
pubmed:22122372 a(CHEBI:amyloid-beta) decreases bp(GO:"regulation of synapse structure or activity")
pubmed:22122372 a(CHEBI:amyloid-beta) decreases bp(GO:"regulation of synapse structure or activity")
pubmed:21214928 a(CHEBI:amyloid-beta) increases bp(GO:"neurofibrillary tangle assembly")
pubmed:22122372 a(CHEBI:amyloid-beta) increases bp(GO:"neurofibrillary tangle assembly")
pubmed:21214928 a(CHEBI:amyloid-beta) association bp(GO:"MAPK cascade")
pubmed:21214928 a(CHEBI:amyloid-beta) association bp(GO:"ERK1 and ERK2 cascade")
pubmed:21214928 a(CHEBI:amyloid-beta) decreases a(MESH:Synapses)
pubmed:19293145 a(CHEBI:amyloid-beta) decreases a(MESH:Synapses)
pubmed:21214928 a(CHEBI:amyloid-beta) decreases bp(GO:memory)
pubmed:25514383 a(CHEBI:amyloid-beta) increases bp(GO:memory)
pubmed:29758300 tloc(a(CHEBI:amyloid-beta), fromLoc(go:0005622 ! intracellular), toLoc(go:0005615 ! "extracellular space")) increases bp(GO:memory)
pubmed:22908190 a(CHEBI:amyloid-beta) decreases bp(GO:memory)
pubmed:21214928 a(CHEBI:amyloid-beta) association bp(MESH:"Synaptic Transmission")
pubmed:21214928 a(CHEBI:amyloid-beta) decreases bp(GO:"long-term synaptic potentiation")
pubmed:21214928 a(CHEBI:amyloid-beta) association a(MESH:"Potassium Channels")
pubmed:21214928 a(CHEBI:amyloid-beta) increases bp(GO:"cell death")
pubmed:21214928 a(CHEBI:amyloid-beta) association complex(p(HGNC:APBA1), p(HGNC:APP))
pubmed:21214928 tloc(a(CHEBI:amyloid-beta), fromLoc(go:0005622 ! intracellular), toLoc(go:0005615 ! "extracellular space")) association complex(p(HGNC:APBA1), p(HGNC:APP))
pubmed:21214928 a(CHEBI:amyloid-beta) association complex(p(HGNC:APBA2), p(HGNC:APP))
pubmed:21214928 tloc(a(CHEBI:amyloid-beta), fromLoc(go:0005622 ! intracellular), toLoc(go:0005615 ! "extracellular space")) association complex(p(HGNC:APBA2), p(HGNC:APP))
pubmed:21214928 a(CHEBI:amyloid-beta) association complex(p(HGNC:APBA3), p(HGNC:APP))
pubmed:21214928 tloc(a(CHEBI:amyloid-beta), fromLoc(go:0005622 ! intracellular), toLoc(go:0005615 ! "extracellular space")) association complex(p(HGNC:APBA3), p(HGNC:APP))
pubmed:21214928 a(CHEBI:amyloid-beta) association a(CHEBI:"phorbol ester")
pubmed:22122372 a(CHEBI:amyloid-beta) decreases bp(GO:"learning or memory")
pubmed:22122372 a(CHEBI:amyloid-beta) increases a(CONSO:CONSO00038)
pubmed:22122372 a(CHEBI:amyloid-beta) increases a(CONSO:CONSO00018)
pubmed:21156028 a(CHEBI:amyloid-beta) increases p(HGNC:DYRK1A)
pubmed:22262751 a(CHEBI:amyloid-beta) association g(DBSNP:rs6656401)
pubmed:19419557 a(CHEBI:amyloid-beta) association bp(GO:"calcium-mediated signaling")
pubmed:19293145 act(a(CHEBI:amyloid-beta)) association bp(GO:"calcium-mediated signaling")
pubmed:26027813 a(CHEBI:amyloid-beta) association a(NIFT:"Cortical Thickness")
pubmed:26996954 a(CHEBI:amyloid-beta) positiveCorrelation a(NIFT:"Grey matter atrophy")
pubmed:30061532 a(CHEBI:amyloid-beta) association path(MESH:"Lewy Body Disease")
pubmed:30515821 a(CHEBI:amyloid-beta) increases act(p(HGNC:CDK5))
pubmed:30515821 a(CHEBI:amyloid-beta) increases p(HGNC:DNM1L, pmod(go:0006468 ! "protein phosphorylation", Ser, 579))
pubmed:19293145 a(CHEBI:amyloid-beta) association bp(GO:"synaptic transmission, cholinergic")
pubmed:19293145 a(CHEBI:amyloid-beta) association bp(GO:"synaptic transmission, cholinergic")
pubmed:19293145 a(CHEBI:amyloid-beta) association p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits")
pubmed:19293145 a(CHEBI:amyloid-beta) association p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits")
pubmed:19293145 a(CHEBI:amyloid-beta) association act(p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits"))
pubmed:19293145 a(CHEBI:amyloid-beta) decreases p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits")
pubmed:19293145 a(CHEBI:amyloid-beta) decreases act(p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits"))
pubmed:19293145 a(CHEBI:amyloid-beta) positiveCorrelation p(HGNC:CHRNA7)
pubmed:19293145 a(CHEBI:amyloid-beta) increases act(p(HGNC:CHRNA7))
pubmed:19293145 a(CHEBI:amyloid-beta) association p(HGNC:CHRNA7)
pubmed:19293145 a(CHEBI:amyloid-beta) decreases act(p(HGNC:CHRNA7))
pubmed:19293145 a(CHEBI:amyloid-beta) causesNoChange p(HGNC:CHRNA7)
pubmed:19293145 a(CHEBI:amyloid-beta) causesNoChange act(p(HGNC:CHRNA7))
pubmed:19293145 a(CHEBI:amyloid-beta) increases p(HGNC:CHRNA7)
pubmed:17009926 a(CHEBI:amyloid-beta) positiveCorrelation p(HGNC:CHRNA7)
pubmed:19293145 a(CHEBI:amyloid-beta) positiveCorrelation p(HGNC:CHRNA4)
pubmed:19293145 a(CHEBI:amyloid-beta) increases p(HGNC:CHRNA4)
pubmed:17009926 a(CHEBI:amyloid-beta) positiveCorrelation p(HGNC:CHRNA4)
pubmed:19293145 a(CHEBI:amyloid-beta) increases bp(GO:"intracellular receptor signaling pathway")
pubmed:19293145 act(a(CHEBI:amyloid-beta)) association p(HGNC:FYN)
pubmed:19293145 a(CHEBI:amyloid-beta) increases act(p(HGNC:FYN))
pubmed:19293145 a(CHEBI:amyloid-beta) increases act(p(FPLX:PI3K))
pubmed:19293145 a(CHEBI:amyloid-beta) increases p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Tyr))
pubmed:19293145 a(CHEBI:amyloid-beta) increases act(p(HGNC:MAPK8))
pubmed:19293145 a(CHEBI:amyloid-beta) increases act(p(HGNC:MAPK14))
pubmed:19293145 a(CHEBI:amyloid-beta) causesNoChange path(CONSO:Neurodegeneration)
pubmed:29758300 tloc(a(CHEBI:amyloid-beta), fromLoc(go:0005622 ! intracellular), toLoc(go:0005615 ! "extracellular space")) decreases path(CONSO:Neurodegeneration)
pubmed:19293145 a(CHEBI:amyloid-beta) decreases bp(MESH:"Neuronal Outgrowth")
pubmed:19293145 a(CHEBI:amyloid-beta) decreases act(a(CHEBI:carbachol))
pubmed:19293145 a(CHEBI:amyloid-beta) increases p(HGNC:MAPK1, pmod(go:0006468 ! "protein phosphorylation"))
pubmed:19293145 a(CHEBI:amyloid-beta) increases p(HGNC:BAX)
pubmed:19293145 a(CHEBI:amyloid-beta) increases act(p(HGNC:BAX))
pubmed:19293145 a(CHEBI:amyloid-beta) decreases p(HGNC:BCL2)
pubmed:19293145 a(CHEBI:amyloid-beta) decreases act(p(HGNC:BCL2))
pubmed:22530628 a(CHEBI:amyloid-beta) increases complex(a(CHEBI:amyloid-beta), p(HGNC:CHRNA7))
pubmed:19293145 a(CHEBI:amyloid-beta) increases act(p(FPLX:JNK))
pubmed:19293145 a(CHEBI:amyloid-beta) increases act(p(FPLX:ERK))
pubmed:19293145 a(CHEBI:amyloid-beta) increases act(p(HGNC:BAD))
pubmed:19293145 a(CHEBI:amyloid-beta) association bp(GO:"choline transport")
pubmed:19293145 a(CHEBI:amyloid-beta) increases act(p(HGNC:CHRNA7, var("p.Leu250Thr")))
pubmed:19293145 a(CHEBI:amyloid-beta) increases act(complex(p(HGNC:CHRNA4), p(HGNC:CHRNB2)))
pubmed:19293145 a(CHEBI:amyloid-beta) decreases act(complex(p(HGNC:CHRNA4), p(HGNC:CHRNB2)))
pubmed:19293145 a(CHEBI:amyloid-beta) decreases act(complex(p(HGNC:CHRNA4), p(HGNC:CHRNB2)))
pubmed:19293145 a(CHEBI:amyloid-beta) causesNoChange act(complex(p(HGNC:CHRNA3), p(HGNC:CHRNB4)))
pubmed:19293145 a(CHEBI:amyloid-beta) decreases act(complex(p(HGNC:CHRNA2), p(HGNC:CHRNB2)))
pubmed:19293145 a(CHEBI:amyloid-beta) decreases act(complex(p(HGNC:CHRNA4), p(HGNC:CHRNA5), p(HGNC:CHRNB2)))
pubmed:19293145 a(CHEBI:amyloid-beta) decreases act(p(HGNC:CHRNA7, var("?")))
pubmed:19293145 a(CHEBI:amyloid-beta) decreases act(a(CHEBI:nicotine))
pubmed:19293145 a(CHEBI:amyloid-beta) increases p(HGNC:CHRNA3)
pubmed:19293145 a(CHEBI:amyloid-beta) decreases p(RGD:Chrna4)
pubmed:19293145 a(CHEBI:amyloid-beta) decreases p(RGD:Chrna7)
pubmed:19293145 a(CHEBI:amyloid-beta) increases r(RGD:Chrna7)
pubmed:19293145 a(CHEBI:amyloid-beta) increases p(MGI:Chat)
pubmed:19293145 a(CHEBI:amyloid-beta) increases r(MGI:Chrna3)
pubmed:17009926 a(CHEBI:amyloid-beta) decreases a(CHEBI:acetylcholine)
pubmed:17009926 a(CHEBI:amyloid-beta) decreases tloc(a(CHEBI:acetylcholine), fromLoc(go:0005622 ! intracellular), toLoc(go:0005615 ! "extracellular space"))
pubmed:25514383 a(CHEBI:amyloid-beta) increases act(a(CHEBI:acetylcholine))
pubmed:17009926 a(CHEBI:amyloid-beta) decreases act(p(FPLX:CHRM))
pubmed:22530628 a(CHEBI:amyloid-beta) positiveCorrelation path(MESH:"Memory Disorders")
pubmed:22530628 a(CHEBI:amyloid-beta) positiveCorrelation path(DOID:dementia)
pubmed:26813123 a(CHEBI:amyloid-beta) increases a(CONSO:"amyloid-beta fibrils")
pubmed:26813123 act(a(CHEBI:amyloid-beta)) association act(p(HGNC:CHRM1))
pubmed:24590577 a(CHEBI:amyloid-beta) decreases act(p(HGNC:CHRM1))
pubmed:31248781 a(CHEBI:amyloid-beta) regulates p(MESH:"Receptors, Islet Amyloid Polypeptide")
pubmed:31248781 act(a(CHEBI:amyloid-beta)) increases path(MESH:"Oxidative Stress")
pubmed:24590577 a(CHEBI:amyloid-beta) decreases complex(p(FPLX:"G_protein"), p(HGNC:CHRM1))
pubmed:26979166 a(CHEBI:amyloid-beta, loc(GO:"extracellular space")) increases bp(GO:"microglial cell activation")
pubmed:30988501 a(CHEBI:amyloid-beta, loc(GO:"extracellular matrix")) increases bp(GO:"microglial cell activation")
pubmed:25514383 a(CHEBI:amyloid-beta) increases act(p(CONSO:"beta-2-containing nAChR"))
pubmed:25514383 act(a(CHEBI:amyloid-beta)) negativeCorrelation p(CONSO:"alpha-7 beta-2 nAChR")
pubmed:25514383 a(CHEBI:amyloid-beta) regulates act(p(FPLX:CHRN))
pubmed:25514383 a(CHEBI:amyloid-beta) decreases act(p(FPLX:CHRN))
pubmed:25514383 a(CHEBI:amyloid-beta) increases act(a(MESH:"alpha7 Nicotinic Acetylcholine Receptor"))
pubmed:25514383 a(CHEBI:amyloid-beta) decreases act(a(MESH:"alpha7 Nicotinic Acetylcholine Receptor"))
pubmed:25514383 a(CHEBI:amyloid-beta) decreases bp(GO:"neuron cellular homeostasis")
pubmed:25514383 a(CHEBI:amyloid-beta) decreases a(GO:synapse)
pubmed:22908190 a(CHEBI:amyloid-beta) decreases act(a(GO:synapse))
pubmed:26010758 a(CHEBI:amyloid-beta) increases bp(GO:locomotion)
pubmed:26010758 a(CHEBI:amyloid-beta) decreases path(MESH:Anxiety)
pubmed:26010758 a(CHEBI:amyloid-beta) association path(MESH:"Interpersonal Relations")
pubmed:26010758 a(CHEBI:amyloid-beta) increases p(HGNC:AIF1)
pubmed:26010758 a(CHEBI:amyloid-beta) increases p(HGNC:PTPRC)
pubmed:26010758 a(CHEBI:amyloid-beta) increases p(HGNC:STAT3, pmod(go:0006468 ! "protein phosphorylation"))
pubmed:26010758 a(CHEBI:amyloid-beta) increases r(HGNC:BACE1)
pubmed:30688256 a(CHEBI:amyloid-beta, loc(MESH:Mitochondria)) increases a(CHEBI:"reactive oxygen species")
pubmed:16566606 a(CHEBI:amyloid-beta) increases a(CHEBI:"reactive oxygen species")
pubmed:30688256 a(CHEBI:amyloid-beta, loc(MESH:Mitochondria)) decreases act(a(MESH:Mitochondria))
pubmed:30688256 a(CHEBI:amyloid-beta, loc(MESH:Mitochondria)) decreases a(MESH:Neurons)
pubmed:12428809 a(CHEBI:amyloid-beta) association bp(GO:"axonal transport")
pubmed:21722302 a(CHEBI:amyloid-beta) association p(HGNC:XBP1)
pubmed:21722302 a(CHEBI:amyloid-beta) decreases tloc(a(CHEBI:"calcium cation"), fromLoc(GO:"endoplasmic reticulum"), toLoc(GO:cytoplasm))
pubmed:29758300 a(CHEBI:amyloid-beta) positiveCorrelation act(complex(GO:"TOR complex"))
pubmed:29758300 a(CHEBI:amyloid-beta) negativeCorrelation bp(GO:macroautophagy)
pubmed:29758300 a(CHEBI:amyloid-beta) increases p(HGNC:TARDBP, pmod(go:0006468 ! "protein phosphorylation"))
pubmed:29758300 a(CHEBI:amyloid-beta) increases p(HGNC:TARDBP)
pubmed:29758300 a(CHEBI:amyloid-beta) association complex(GO:"gamma-secretase complex")
pubmed:29758300 a(CHEBI:amyloid-beta) positiveCorrelation p(HGNC:PICALM)
pubmed:29758300 a(CHEBI:amyloid-beta) negativeCorrelation p(HGNC:SORL1)
pubmed:14556719 a(CHEBI:amyloid-beta) decreases act(complex(GO:"proteasome complex"))
pubmed:22908190 a(CHEBI:amyloid-beta) negativeCorrelation act(complex(GO:"proteasome complex"))
pubmed:14556719 a(CHEBI:amyloid-beta) decreases bp(GO:"proteasome-mediated ubiquitin-dependent protein catabolic process")
pubmed:22908190 a(CHEBI:amyloid-beta) positiveCorrelation bp(GO:endocytosis)
pubmed:22908190 a(CHEBI:amyloid-beta) positiveCorrelation bp(GO:endocytosis)
pubmed:22908190 tloc(a(CHEBI:amyloid-beta), fromLoc(GO:cytosol), toLoc(GO:autolysosome)) positiveCorrelation a(CHEBI:"amyloid-beta polypeptide 42")
pubmed:25784053 a(CHEBI:amyloid-beta) decreases act(p(FPLX:Proteasome))
pubmed:24027553 a(CHEBI:amyloid-beta) increases p(HGNC:MAPT, frag("?", "17kD"))
pubmed:24027553 a(CHEBI:amyloid-beta) increases p(HGNC:MAPT, frag("?", "35kD"))
pubmed:24027553 a(CHEBI:amyloid-beta) increases p(HGNC:MAPT, frag("?", "24kD"))
pubmed:24027553 a(CHEBI:amyloid-beta) increases p(CONSO:"Tau C3")
pubmed:30126037 a(CHEBI:amyloid-beta) causesNoChange p(MGI:Cdkn2a)
pubmed:30985105 a(CHEBI:amyloid-beta) negativeCorrelation p(HGNC:APP, pmod(CONSO:O-GlcNAcylation))
pubmed:30985105 a(CHEBI:amyloid-beta) association bp(GO:cognition)
pubmed:26195256 a(CHEBI:amyloid-beta) positiveCorrelation g(CONSO:"APOE e4")
pubmed:26631930 a(CHEBI:amyloid-beta) increases path(CONSO:Excitotoxicity)
pubmed:26631930 a(CHEBI:amyloid-beta) increases path(CONSO:Excitotoxicity)
pubmed:29626319 a(CHEBI:amyloid-beta) increases bp(GO:"response to oxidative stress")
pubmed:29626319 a(CHEBI:amyloid-beta) positiveCorrelation bp(GO:aging)
pubmed:29421605 a(CHEBI:amyloid-beta) positiveCorrelation bp(GO:aging)
pubmed:29626319 a(CHEBI:amyloid-beta) positiveCorrelation path(MESH:"Diabetes Mellitus")
pubmed:29626319 a(CHEBI:amyloid-beta) increases act(p(HGNC:MMP2))
pubmed:29626319 a(CHEBI:amyloid-beta) increases act(p(HGNC:MMP3))
pubmed:29626319 a(CHEBI:amyloid-beta) increases act(p(HGNC:MMP9))
pubmed:29626319 a(CHEBI:amyloid-beta) decreases a(MESH:"Cerebrospinal Fluid")
pubmed:29626319 deg(a(CHEBI:amyloid-beta)) association p(HGNC:AQP4)
pubmed:19251756 a(CHEBI:amyloid-beta) increases bp(GO:"response to nitrosative stress")
pubmed:19251756 a(CHEBI:amyloid-beta) positiveCorrelation complex(p(HGNC:MAPT), p(INTERPRO:"Triosephosphate isomerase", pmod(go:0017014 ! "protein nitrosylation")))
pubmed:16566606 a(CHEBI:amyloid-beta) increases a(CHEBI:"reactive nitrogen species")
pubmed:29221819 a(CHEBI:amyloid-beta) positiveCorrelation p(MGI:Dyrk1a)
pubmed:28877763 a(CHEBI:amyloid-beta) increases act(p(HGNC:SYK))
pubmed:28877763 a(CHEBI:amyloid-beta) increases a(CONSO:"dystrophic neurite")
pubmed:26118667 a(CHEBI:amyloid-beta, loc(MESH:"Intracellular Space")) increases act(p(FPLX:CAPN))
pubmed:22156579 a(CHEBI:amyloid-beta) increases p(RGD:Mapt, pmod(go:0006468 ! "protein phosphorylation", Ser, 262))
pubmed:22156579 a(CHEBI:amyloid-beta) increases p(RGD:Mapt, pmod(go:0006468 ! "protein phosphorylation", Ser, 356))
pubmed:22156579 a(CHEBI:amyloid-beta) increases act(p(HGNC:MARK4))
pubmed:22156579 a(CHEBI:amyloid-beta) increases p(CONSO:"Tau epitope, PHF1", pmod(go:0006468 ! "protein phosphorylation"))
pubmed:25672970 a(CHEBI:amyloid-beta) increases bp(GO:"neuroinflammatory response")
pubmed:28855586 act(a(CHEBI:amyloid-beta)) negativeCorrelation p(HGNC:MAPT, pmod(go:0006473 ! "protein acetylation", Lys, 163), pmod(go:0006473 ! "protein acetylation", Lys, 280), pmod(go:0006473 ! "protein acetylation", Lys, 281), pmod(go:0006473 ! "protein acetylation", Lys, 369))
pubmed:25378699 a(CHEBI:amyloid-beta) increases p(RGD:Mapt, pmod(CONSO:hyperphosphorylation), pmod(go:0016925 ! "protein sumoylation"))
pubmed:18675254 a(CHEBI:amyloid-beta) negativeCorrelation p(HGNC:APP, pmod(go:0016925 ! "protein sumoylation", Lys, 587))
pubmed:18675254 a(CHEBI:amyloid-beta) negativeCorrelation p(HGNC:APP, pmod(go:0016925 ! "protein sumoylation", Lys, 595))
pubmed:28019679 a(CHEBI:amyloid-beta) increases bp(GO:"innate immune response")
pubmed:28019679 a(CHEBI:amyloid-beta) increases act(complex(GO:"NLRP3 inflammasome complex"))
pubmed:23702978 a(CHEBI:amyloid-beta) increases act(complex(GO:"NLRP3 inflammasome complex"))
pubmed:28019679 a(CHEBI:amyloid-beta) increases a(CHEBI:"nitric oxide")
pubmed:28019679 a(CHEBI:amyloid-beta) increases act(complex(GO:"NLRP1 inflammasome complex"))
pubmed:28019679 a(CHEBI:amyloid-beta) increases act(p(HGNC:CASP1))
pubmed:23702978 a(CHEBI:amyloid-beta) increases act(p(HGNC:NLRP3))
pubmed:27314526 a(CHEBI:amyloid-beta) association p(HGNC:NLRP3)
pubmed:23702978 a(CHEBI:amyloid-beta) increases act(p(FPLX:TLR))
pubmed:24561250 a(CHEBI:amyloid-beta) increases act(complex(GO:"inflammasome complex"))
pubmed:24561250 a(CHEBI:amyloid-beta) increases bp(GO:phagocytosis)
pubmed:24561250 a(CHEBI:amyloid-beta) decreases a(GO:lysosome)
pubmed:30988501 a(CHEBI:amyloid-beta, loc(GO:intracellular)) biomarkerFor path(DOID:"Alzheimer's disease")
pubmed:30046111 bp(GO:phagocytosis) regulates deg(a(CHEBI:amyloid-beta))
pubmed:29626319 bp(GO:phagocytosis) increases deg(a(CHEBI:amyloid-beta))
pubmed:29626319 bp(GO:phagocytosis) increases deg(a(CHEBI:amyloid-beta))
pubmed:29626319 bp(GO:phagocytosis) increases deg(a(CHEBI:amyloid-beta))
pubmed:30967783 bp(GO:phagocytosis) increases deg(a(NCIT:C120869))
pubmed:29626319 bp(GO:phagocytosis) association p(HGNC:TREM2)
pubmed:29626319 bp(GO:phagocytosis) association p(HGNC:ABCA7)
pubmed:29626319 bp(GO:phagocytosis) association p(HGNC:CD33)
pubmed:29626319 bp(GO:phagocytosis) increases deg(a(CHEBI:"amyloid-beta polypeptide 42"))
pubmed:29626319 bp(GO:phagocytosis) decreases p(HGNC:MAPT)
pubmed:24561250 bp(GO:phagocytosis) increases act(complex(GO:"NLRP3 inflammasome complex"))
pubmed:30988501 bp(GO:phagocytosis) increases bp(GO:"activation of innate immune response")
pubmed:30046111 a(MESH:Microglia) regulates deg(a(CHEBI:amyloid-beta))
pubmed:26195256 a(MESH:Microglia) decreases a(CHEBI:amyloid-beta, loc(MESH:"Extracellular Fluid"))
pubmed:26195256 act(a(MESH:Microglia)) decreases a(CHEBI:amyloid-beta)
pubmed:28745240 act(a(MESH:Microglia)) increases p(HGNC:TNF)
pubmed:30967783 a(MESH:Microglia) increases p(HGNC:TNF)
pubmed:30988501 a(MESH:Microglia) increases tloc(p(HGNC:TNF), fromLoc(go:0005622 ! intracellular), toLoc(go:0005615 ! "extracellular space"))
pubmed:28745240 act(a(MESH:Microglia)) increases p(HGNC:IL1B)
pubmed:30967783 a(MESH:Microglia) increases tloc(p(HGNC:IL1B), fromLoc(go:0005622 ! intracellular), toLoc(go:0005615 ! "extracellular space"))
pubmed:28745240 act(a(MESH:Microglia)) increases p(HGNC:IL6)
pubmed:30967783 a(MESH:Microglia) increases p(HGNC:IL6)
pubmed:30967783 a(MESH:Microglia) increases tloc(p(HGNC:IL6), fromLoc(go:0005622 ! intracellular), toLoc(go:0005615 ! "extracellular space"))
pubmed:28745240 act(a(MESH:Microglia)) increases p(HGNC:CXCL8)
pubmed:28745240 act(a(MESH:Microglia)) increases bp(GO:"neuron death")
pubmed:25652642 act(a(MESH:Microglia)) positiveCorrelation a(CHEBI:"amyloid-beta polypeptide 42")
pubmed:27794524 a(MESH:Microglia) directlyIncreases tloc(a(CHEBI:"reactive oxygen species"), fromLoc(go:0005622 ! intracellular), toLoc(go:0005615 ! "extracellular space"))
pubmed:27794524 a(MESH:Microglia) directlyIncreases a(CHEBI:"reactive oxygen species")
pubmed:27794524 a(MESH:Microglia) directlyIncreases tloc(a(CHEBI:"reactive nitrogen species"), fromLoc(go:0005622 ! intracellular), toLoc(go:0005615 ! "extracellular space"))
pubmed:27794524 a(MESH:Microglia) directlyIncreases a(CHEBI:"reactive nitrogen species")
pubmed:27794524 a(MESH:Microglia) directlyIncreases a(CHEBI:"nitric oxide")
pubmed:27794524 a(MESH:Microglia) association a(PUBCHEM:54677946)
pubmed:26445701 act(a(MESH:Microglia)) increases path(MESH:Inflammation)
pubmed:30967783 a(MESH:Microglia) decreases path(MESH:Inflammation)
pubmed:30967783 a(MESH:Microglia) regulates bp(MESH:Homeostasis)
pubmed:30967783 a(MESH:Microglia) increases complex(p(HGNC:CX3CL1), p(HGNC:CX3CR1))
pubmed:30967783 a(MESH:Microglia) increases bp(MESH:"Neuronal Plasticity")
pubmed:30967783 a(MESH:Microglia) increases bp(MESH:"Neuronal Plasticity")
pubmed:30967783 a(MESH:Microglia) increases bp(MESH:"Neuronal Plasticity")
pubmed:30967783 a(MESH:Microglia) decreases bp(MESH:"Neuronal Plasticity")
pubmed:30967783 a(MESH:Microglia) increases bp(GO:"generation of neurons")
pubmed:30967783 a(MESH:Microglia) increases p(HGNC:IGF1)
pubmed:30967783 a(MESH:Microglia) increases bp(GO:"learning or memory")
pubmed:30988501 a(MESH:Microglia) increases bp(GO:"learning or memory")
pubmed:30967783 a(MESH:Microglia) increases a(GO:synapse)
pubmed:30967783 a(MESH:Microglia) increases p(HGNC:BDNF)
pubmed:30967783 a(MESH:Microglia) increases bp(GO:"apoptotic cell clearance")
pubmed:30967783 a(MESH:Microglia) increases deg(p(MESH:Proteins, pmod(CONSO:misfolded)))
pubmed:30967783 a(MESH:Microglia) decreases p(MESH:Proteins, pmod(CONSO:misfolded))
pubmed:30967783 a(MESH:Microglia) increases p(HGNC:IFNG)
pubmed:30967783 a(MESH:Microglia) increases p(MESH:Interleukin-23)
pubmed:30967783 a(MESH:Microglia) increases p(HGNC:NOS2)
pubmed:30967783 a(MESH:Microglia) increases p(HGNC:CCL4)
pubmed:30967783 a(MESH:Microglia) increases p(HGNC:CCL5)
pubmed:30967783 a(MESH:Microglia) increases tloc(p(HGNC:CCL5), fromLoc(go:0005622 ! intracellular), toLoc(go:0005615 ! "extracellular space"))
pubmed:30967783 a(MESH:Microglia) increases p(HGNC:CCL8)
pubmed:30967783 a(MESH:Microglia) increases p(HGNC:CXCL2)
pubmed:30967783 a(MESH:Microglia) increases p(HGNC:PF4)
pubmed:30967783 a(MESH:Microglia) increases p(HGNC:CXCL9)
pubmed:30967783 a(MESH:Microglia) isA a(MESH:"Antigen-Presenting Cells")
pubmed:30967783 a(MESH:Microglia) isA a(MESH:"Antigen-Presenting Cells")
pubmed:30967783 a(MESH:Microglia) increases bp(MESH:"Adaptive Immunity")
pubmed:30967783 a(MESH:Microglia) increases p(HGNC:IL4)
pubmed:30967783 a(MESH:Microglia) increases p(HGNC:IL10)
pubmed:30967783 a(MESH:Microglia) increases p(HGNC:IL13)
pubmed:30967783 a(MESH:Microglia) increases p(HGNC:TGFB1)
pubmed:30967783 a(MESH:Microglia) regulates bp(MESH:Immunity)
pubmed:30967783 a(MESH:Microglia) increases bp(GO:"tissue remodeling")
pubmed:30967783 a(MESH:Microglia) increases bp(GO:angiogenesis)
pubmed:30967783 a(MESH:Microglia) increases deg(a(MESH:Parasites))
pubmed:30967783 a(MESH:Microglia) increases bp(GO:"oligodendrocyte differentiation")
pubmed:30967783 a(MESH:Microglia) increases bp(MESH:Remyelination)
pubmed:30967783 a(MESH:Microglia) increases bp(GO:"brain development")
pubmed:28669544 a(MESH:Microglia) regulates bp(GO:"brain development")
pubmed:30967783 a(MESH:Microglia) regulates bp(MESH:"Neural Pathways")
pubmed:28669544 a(MESH:Microglia) regulates bp(MESH:"Neural Pathways")
pubmed:30967783 a(MESH:Microglia) decreases bp(GO:cognition)
pubmed:30967783 a(MESH:Microglia) increases tloc(p(HGNC:IL18), fromLoc(go:0005622 ! intracellular), toLoc(go:0005615 ! "extracellular space"))
pubmed:30967783 a(MESH:Microglia) increases tloc(p(HGNC:CCL2), fromLoc(go:0005622 ! intracellular), toLoc(go:0005615 ! "extracellular space"))
pubmed:30967783 a(MESH:Microglia) increases path(DOID:"multiple sclerosis")
pubmed:30967783 a(MESH:Microglia) increases deg(a(MESH:"Myelin Sheath"))
pubmed:30967783 a(MESH:Microglia) increases bp(GO:phagocytosis)
pubmed:29626319 act(a(MESH:Microglia)) increases bp(GO:phagocytosis)
pubmed:29626319 a(MESH:Microglia) increases bp(GO:phagocytosis)
pubmed:30967783 a(MESH:Microglia) increases bp(MESH:Neuroprotection)
pubmed:30967783 a(MESH:Microglia) increases bp(MESH:Neuroprotection)
pubmed:30967783 a(MESH:Microglia) increases a(MESH:Cytokines)
pubmed:26195256 act(a(MESH:Microglia)) increases a(MESH:Cytokines)
pubmed:30967783 a(MESH:Microglia) increases p(HGNC:TREM2)
pubmed:30967783 act(a(MESH:Microglia)) increases a(MESH:"Glatiramer Acetate")
pubmed:23178521 a(MESH:Microglia) increases a(MESH:"alpha7 Nicotinic Acetylcholine Receptor")
pubmed:23383175 a(MESH:Microglia) positiveCorrelation a(MESH:Astrocytes)
pubmed:23383175 a(MESH:Microglia) negativeCorrelation a(GO:"myelin sheath")
pubmed:29202785 act(a(MESH:Microglia)) negativeCorrelation p(CONSO:"Tau isoform F (441 aa)", var("p.Ile277Pro"), var("p.Ile308Pro"), var("p.Lys280del"))
pubmed:29202785 act(a(MESH:Microglia)) positiveCorrelation p(CONSO:"Tau isoform F (441 aa)", var("p.Lys280del"))
pubmed:28528849 a(MESH:Microglia) regulates act(p(CONSO:"Tau oligomers", var("p.Lys280del")))
pubmed:29626319 act(a(MESH:Microglia)) increases bp(GO:"immune response")
pubmed:29626319 act(a(MESH:Microglia)) increases bp(GO:"cytokine production involved in inflammatory response")
pubmed:29626319 act(a(MESH:Microglia)) increases bp(GO:"inflammatory response")
pubmed:29238289 a(MESH:Microglia) increases tloc(p(HGNC:MAPT), fromLoc(go:0005622 ! intracellular), toLoc(go:0005615 ! "extracellular space"))
pubmed:28669544 a(MESH:Microglia) isA bp(MESH:"Immunity, Innate")
pubmed:28669544 a(MESH:Microglia) regulates path(MESH:"Neural Pathways")
pubmed:28669544 a(MESH:Microglia) regulates bp(GO:"nervous system development")
pubmed:28669544 a(MESH:Microglia) decreases a(MESH:Synapses)
pubmed:28669544 a(MESH:Microglia) directlyDecreases a(MESH:Synapses)
pubmed:28669544 a(MESH:Microglia) decreases path(MESH:"Protein Aggregation, Pathological")
pubmed:28669544 a(MESH:Microglia) association path(DOID:"neurodegenerative disease")
pubmed:28669544 a(MESH:Microglia) regulates path(MESH:"Immune System")
pubmed:28669544 a(MESH:Microglia) regulates path(MESH:Phagocytosis)
pubmed:28669544 a(MESH:Microglia) regulates deg(p(CONSO:"protein aggregates"))
pubmed:28669544 a(MESH:Microglia, loc(CONSO:"amyloid-beta oligomers")) increases path(MESH:"Neuronal Plasticity")
pubmed:27314526 a(MESH:Microglia) increases p(HGNC:NLRP3)
pubmed:27314526 a(MESH:Microglia) increases p(HGNC:P2RX7)
pubmed:27314526 a(MESH:Microglia) increases p(HGNC:TLR4)
pubmed:30988501 a(MESH:Microglia) increases bp(MESH:"Immunologic Surveillance")
pubmed:30988501 a(MESH:Microglia) increases bp(GO:"complement-mediated synapse pruning")
pubmed:30988501 a(MESH:Microglia) increases bp(GO:"central nervous system development")
pubmed:30988501 a(MESH:Microglia) association bp(GO:"synaptic signaling")
pubmed:30988501 a(MESH:Microglia) increases tloc(a(MESH:"Extracellular Vesicles"), fromLoc(go:0005622 ! intracellular), toLoc(go:0005615 ! "extracellular space"))
pubmed:30988501 a(MESH:Microglia) increases bp(GO:"regulation of neuronal synaptic plasticity")
pubmed:30988501 a(MESH:Microglia) increases bp(GO:"motor learning")
pubmed:30046111 a(MESH:Monocytes) regulates deg(a(CHEBI:amyloid-beta))
pubmed:29626319 a(MESH:Monocytes) increases deg(a(CHEBI:amyloid-beta))
pubmed:29626319 a(MESH:Monocytes) increases deg(a(CHEBI:amyloid-beta))
pubmed:30967783 a(MESH:Monocytes, loc(MESH:"Blood-Brain Barrier")) directlyIncreases a(MESH:Macrophages, loc(MESH:"Blood-Brain Barrier"))
pubmed:30967783 a(MESH:Monocytes, loc(GO:"node of Ranvier")) increases path(HP:"CNS demyelination")
pubmed:30967783 a(MESH:Monocytes) causesNoChange a(MESH:Microglia)
pubmed:30046111 a(MESH:Macrophages) regulates deg(a(CHEBI:amyloid-beta))
pubmed:30046111 a(MESH:Macrophages) association a(CHEBI:amyloid-beta)
pubmed:26195256 a(MESH:Macrophages) increases deg(a(CHEBI:amyloid-beta))
pubmed:30962309 a(MESH:Macrophages) increases m(MIRBASE:hsa-mir-302b)
pubmed:27794524 a(MESH:Macrophages) directlyIncreases a(CHEBI:"reactive oxygen species")
pubmed:27794524 a(MESH:Macrophages) directlyIncreases a(CHEBI:"reactive nitrogen species")
pubmed:27794524 a(MESH:Macrophages) directlyIncreases a(CHEBI:"nitric oxide")
pubmed:30967783 a(MESH:Macrophages) regulates bp(MESH:Homeostasis)
pubmed:30967783 a(MESH:Macrophages) increases bp(GO:"neuroinflammatory response")
pubmed:30967783 a(MESH:Macrophages) increases path(DOID:"multiple sclerosis")
pubmed:30967783 a(MESH:Macrophages) increases bp(MESH:Neuroprotection)
pubmed:30967783 a(MESH:Macrophages) increases bp(MESH:Neuroprotection)
pubmed:30967783 a(MESH:Macrophages, loc(MESH:Brain)) increases bp(MESH:Neuroprotection)
pubmed:30967783 a(MESH:Macrophages) decreases path(MESH:Inflammation)
pubmed:30967783 a(MESH:Macrophages) increases path(MESH:Inflammation)
pubmed:30967783 a(MESH:Macrophages) increases bp(GO:"establishment of blood-brain barrier")
pubmed:30967783 a(MESH:Macrophages) increases bp(MESH:Immunity)
pubmed:30967783 a(MESH:Macrophages) increases bp(MESH:Immunity)
pubmed:30967783 a(MESH:Macrophages) increases a(MESH:"Leukocytes, Mononuclear")
pubmed:30967783 a(MESH:Macrophages) decreases act(a(MESH:"Leukocytes, Mononuclear"))
pubmed:30967783 a(MESH:Macrophages) decreases a(MESH:"Leukocytes, Mononuclear", loc(MESH:"Central Nervous System"))
pubmed:30967783 a(MESH:Macrophages) isA a(MESH:"Antigen-Presenting Cells")
pubmed:30967783 a(MESH:Macrophages) isA a(MESH:"Antigen-Presenting Cells")
pubmed:30967783 a(MESH:Macrophages) isA a(MESH:"Antigen-Presenting Cells")
pubmed:30967783 a(MESH:Macrophages) decreases a(NCIT:C120869)
pubmed:30967783 a(MESH:Macrophages) increases bp(GO:"cerebrospinal fluid secretion")
pubmed:30967783 a(MESH:Macrophages) increases bp(GO:"cerebrospinal fluid circulation")
pubmed:30967783 a(MESH:Macrophages) increases p(HGNC:TRPM2)
pubmed:30967783 a(MESH:Macrophages) increases tloc(p(HGNC:IL6), fromLoc(go:0005622 ! intracellular), toLoc(go:0005615 ! "extracellular space"))
pubmed:30967783 a(MESH:Macrophages) increases tloc(p(HGNC:IL12B), fromLoc(go:0005622 ! intracellular), toLoc(go:0005615 ! "extracellular space"))
pubmed:30967783 a(MESH:Macrophages) increases tloc(p(HGNC:TNF), fromLoc(go:0005622 ! intracellular), toLoc(go:0005615 ! "extracellular space"))
pubmed:30967783 a(MESH:Macrophages) increases tloc(p(HGNC:IL1A), fromLoc(go:0005622 ! intracellular), toLoc(go:0005615 ! "extracellular space"))
pubmed:30967783 a(MESH:Macrophages) increases tloc(p(MESH:Interleukin-23), fromLoc(go:0005622 ! intracellular), toLoc(go:0005615 ! "extracellular space"))
pubmed:30967783 a(MESH:Macrophages) increases p(HGNC:CCR4)
pubmed:30967783 a(MESH:Macrophages) increases path(HP:"CNS demyelination")
pubmed:30967783 a(MESH:Macrophages) increases p(HGNC:TREM1)
pubmed:30967783 a(MESH:Macrophages) increases p(MESH:"Histocompatibility Antigens Class II")
pubmed:30967783 a(MESH:Macrophages) increases path(EFO:"experimental autoimmune encephalomyelitis")
pubmed:30967783 a(MESH:Macrophages) decreases path(EFO:"experimental autoimmune encephalomyelitis")
pubmed:30967783 a(MESH:Macrophages) increases p(HGNC:VCAM1)
pubmed:30967783 a(MESH:Macrophages) increases p(HGNC:ICAM1)
pubmed:30967783 a(MESH:Macrophages) increases p(HGNC:CCL2)
pubmed:30967783 a(MESH:Macrophages) increases p(HGNC:CCL3)
pubmed:30967783 a(MESH:Macrophages) increases bp(GO:"T cell activation")
pubmed:30967783 a(MESH:Macrophages) increases p(MESH:"Nerve Growth Factors")
pubmed:30967783 a(MESH:Macrophages) increases p(MESH:"Anti-Inflammatory Agents")
pubmed:30967783 a(MESH:Macrophages) decreases p(HGNC:IFNG)
pubmed:30967783 a(MESH:Macrophages, loc(MESH:Brain)) regulates a(MESH:Microglia)
pubmed:30046111 a(CONSO:CONSO00018) positiveCorrelation path(MESH:"Alzheimer Disease")
pubmed:21718217 a(CONSO:CONSO00018) association path(MESH:"Alzheimer Disease")
pubmed:30046111 a(CONSO:CONSO00018) decreases bp(GO:"neuron cellular homeostasis")
pubmed:30046111 a(CONSO:CONSO00018) increases path(MESH:"Problem Behavior")
pubmed:29196815 a(CONSO:CONSO00018) causesNoChange bp(GO:"neuron death")
pubmed:29196815 a(CONSO:CONSO00018) causesNoChange bp(GO:"astrocyte activation")
pubmed:22122372 a(CONSO:CONSO00018) association a(MESH:"Amyloid beta-Peptides")
pubmed:22122372 a(CONSO:CONSO00018) increases path(MESH:"Plaque, Amyloid")
pubmed:30046111 path(MESH:"Alzheimer Disease") positiveCorrelation a(CONSO:CONSO00018)
pubmed:21718217 path(MESH:"Alzheimer Disease") association a(CONSO:CONSO00018)
pubmed:22040696 path(MESH:"Alzheimer Disease") increases a(CONSO:CONSO00018)
pubmed:30046111 path(MESH:"Alzheimer Disease") association act(a(MESH:"Lymphatic Vessels"))
pubmed:30046111 path(MESH:"Alzheimer Disease") positiveCorrelation a(CHEBI:amyloid-beta)
pubmed:30046111 path(MESH:"Alzheimer Disease") positiveCorrelation a(CHEBI:amyloid-beta)
pubmed:30046111 path(MESH:"Alzheimer Disease") positiveCorrelation a(CHEBI:amyloid-beta)
pubmed:29196815 path(MESH:"Alzheimer Disease") positiveCorrelation a(CHEBI:amyloid-beta)
pubmed:29196815 path(MESH:"Alzheimer Disease") positiveCorrelation a(CHEBI:amyloid-beta)
pubmed:19293145 path(MESH:"Alzheimer Disease") association tloc(a(CHEBI:amyloid-beta), fromLoc(go:0005622 ! intracellular), toLoc(go:0005615 ! "extracellular space"))
pubmed:19293145 path(MESH:"Alzheimer Disease") association a(CHEBI:amyloid-beta)
pubmed:25514383 path(MESH:"Alzheimer Disease") positiveCorrelation a(CHEBI:amyloid-beta)
pubmed:14556719 path(MESH:"Alzheimer Disease") association a(CHEBI:amyloid-beta)
pubmed:26195256 path(MESH:"Alzheimer Disease") decreases deg(a(CHEBI:amyloid-beta))
pubmed:29626319 path(MESH:"Alzheimer Disease") decreases deg(a(CHEBI:amyloid-beta))
pubmed:29626319 path(MESH:"Alzheimer Disease") increases a(CHEBI:amyloid-beta)
pubmed:29980653 path(MESH:"Alzheimer Disease") positiveCorrelation a(CHEBI:amyloid-beta)
pubmed:30663117 path(MESH:"Alzheimer Disease") positiveCorrelation r(HGNC:BACE1, loc(GO:cytoplasm))
pubmed:21329555 path(MESH:"Alzheimer Disease") positiveCorrelation r(HGNC:BACE1)
pubmed:30663117 path(MESH:"Alzheimer Disease") positiveCorrelation r(HGNC:BACE1-AS)
pubmed:30663117 path(MESH:"Alzheimer Disease") association g(HGNC:MIR384)
pubmed:30663117 path(MESH:"Alzheimer Disease") association g(HGNC:MIR153-1)
pubmed:30663117 path(MESH:"Alzheimer Disease") association g(HGNC:MIR101-1)
pubmed:30663117 path(MESH:"Alzheimer Disease") association g(HGNC:MIR9-1)
pubmed:30663117 path(MESH:"Alzheimer Disease") decreases g(HGNC:MIR9-1)
pubmed:16273023 path(MESH:"Alzheimer Disease") decreases a(CHEBI:acetylcholine)
pubmed:16273023 path(MESH:"Alzheimer Disease") decreases act(a(CHEBI:acetylcholine))
pubmed:26218288 path(MESH:"Alzheimer Disease") negativeCorrelation a(CHEBI:acetylcholine)
pubmed:19293145 path(MESH:"Alzheimer Disease") decreases a(CHEBI:acetylcholine)
pubmed:25514383 path(MESH:"Alzheimer Disease") decreases a(CHEBI:acetylcholine)
pubmed:16273023 path(MESH:"Alzheimer Disease") negativeCorrelation a(CL:"cholinergic neuron")
pubmed:16273023 path(MESH:"Alzheimer Disease") negativeCorrelation act(p(HGNC:ACHE))
pubmed:26813123 path(MESH:"Alzheimer Disease") association p(HGNC:ACHE)
pubmed:18986241 path(MESH:"Alzheimer Disease") decreases p(HGNC:ACHE)
pubmed:18986241 path(MESH:"Alzheimer Disease") causesNoChange act(p(HGNC:ACHE))
pubmed:18986241 path(MESH:"Alzheimer Disease") decreases act(p(HGNC:ACHE))
pubmed:18986241 path(MESH:"Alzheimer Disease") decreases act(p(HGNC:ACHE))
pubmed:11230871 path(MESH:"Alzheimer Disease") decreases act(p(HGNC:ACHE))
pubmed:11230871 path(MESH:"Alzheimer Disease") negativeCorrelation act(p(HGNC:ACHE))
pubmed:11230871 path(MESH:"Alzheimer Disease") decreases act(p(HGNC:ACHE))
pubmed:16273023 path(MESH:"Alzheimer Disease") association p(HGNC:REST)
pubmed:16273023 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:SEPT2)
pubmed:16273023 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:SEPT3)
pubmed:16273023 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:SEPT5)
pubmed:" 23273601" path(MESH:"Alzheimer Disease") negativeCorrelation r(HGNC:VAMP2)
pubmed:" 23273601" path(MESH:"Alzheimer Disease") negativeCorrelation r(HGNC:SNAP25)
pubmed:" 23273601" path(MESH:"Alzheimer Disease") negativeCorrelation r(HGNC:SYN1)
pubmed:" 23273601" path(MESH:"Alzheimer Disease") negativeCorrelation r(HGNC:SYN2)
pubmed:" 23273601" path(MESH:"Alzheimer Disease") negativeCorrelation r(HGNC:SYT1)
pubmed:" 23273601" path(MESH:"Alzheimer Disease") negativeCorrelation r(HGNC:SYT5)
pubmed:" 23273601" path(MESH:"Alzheimer Disease") negativeCorrelation r(HGNC:DNM1)
pubmed:" 23273601" path(MESH:"Alzheimer Disease") negativeCorrelation r(HGNC:DNM1L)
pubmed:" 23273601" path(MESH:"Alzheimer Disease") negativeCorrelation r(HGNC:SYNPO)
pubmed:" 23273601" path(MESH:"Alzheimer Disease") negativeCorrelation r(HGNC:RAB3A)
pubmed:" 23273601" path(MESH:"Alzheimer Disease") negativeCorrelation r(HGNC:SEC22B)
pubmed:" 23273601" path(MESH:"Alzheimer Disease") negativeCorrelation r(HGNC:SNCA)
pubmed:" 23273601" path(MESH:"Alzheimer Disease") negativeCorrelation r(HGNC:SNCB)
pubmed:" 23273601" path(MESH:"Alzheimer Disease") negativeCorrelation r(HGNC:STXBP5L)
pubmed:" 23273601" path(MESH:"Alzheimer Disease") negativeCorrelation r(HGNC:STXBP6)
pubmed:" 23273601" path(MESH:"Alzheimer Disease") negativeCorrelation r(HGNC:BSN)
pubmed:" 23273601" path(MESH:"Alzheimer Disease") negativeCorrelation r(HGNC:PCLO)
pubmed:" 23273601" path(MESH:"Alzheimer Disease") positiveCorrelation r(HGNC:SNAP23)
pubmed:" 23273601" path(MESH:"Alzheimer Disease") positiveCorrelation r(HGNC:SYNPO2)
pubmed:" 23273601" path(MESH:"Alzheimer Disease") positiveCorrelation r(HGNC:VAMP1)
pubmed:18986241 path(MESH:"Alzheimer Disease") causesNoChange r(HGNC:VAMP1)
pubmed:26218288 path(MESH:"Alzheimer Disease") positiveCorrelation path(HP:"Neuronal loss in central nervous system")
pubmed:24107444 path(MESH:"Alzheimer Disease") negativeCorrelation g(HGNC:PSEN1)
pubmed:17361039 path(MESH:"Alzheimer Disease") negativeCorrelation r(HGNC:SLC1A3)
pubmed:17361039 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:SLC1A3)
pubmed:17361039 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:SLC1A3)
pubmed:17361039 path(MESH:"Alzheimer Disease") negativeCorrelation r(HGNC:SLC1A2)
pubmed:17361039 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:SLC1A2)
pubmed:17361039 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:SLC1A2)
pubmed:17361039 path(MESH:"Alzheimer Disease") positiveCorrelation r(HGNC:GRIK4)
pubmed:17361039 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:POLR2M)
pubmed:17361039 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:GRIA4)
pubmed:25932647 path(MESH:"Alzheimer Disease") negativeCorrelation p(INTERPRO:"Serine/threonine-protein kinase MARK/par1")
pubmed:21329555 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:RELA)
pubmed:25652642 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:RELA, loc(GO:nucleus))
pubmed:21329555 path(MESH:"Alzheimer Disease") positiveCorrelation path(MESH:Inflammation)
pubmed:27288790 path(MESH:"Alzheimer Disease") positiveCorrelation path(MESH:Inflammation)
pubmed:24027553 path(MESH:"Alzheimer Disease") positiveCorrelation path(MESH:Inflammation)
pubmed:28745240 path(MESH:"Alzheimer Disease") association p(HGNC:IL6)
pubmed:25652642 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:IL6)
pubmed:28745240 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:TNF)
pubmed:27288790 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:TNF)
pubmed:25652642 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:TNF)
pubmed:29179999 path(MESH:"Alzheimer Disease") positiveCorrelation p(FPLX:NFkappaB)
pubmed:27288790 path(MESH:"Alzheimer Disease") positiveCorrelation act(p(FPLX:NFkappaB))
pubmed:27288790 path(MESH:"Alzheimer Disease") negativeCorrelation bp(GO:"regulation of synaptic plasticity")
pubmed:27288790 path(MESH:"Alzheimer Disease") positiveCorrelation a(CHEBI:"reactive oxygen species")
pubmed:27288790 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:IL1B)
pubmed:25652642 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:IL1B)
pubmed:24561250 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:IL1B)
pubmed:27314526 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:IL1B)
pubmed:27288790 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:IL18)
pubmed:24561250 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:IL18)
pubmed:27314526 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:IL18)
pubmed:27314526 path(MESH:"Alzheimer Disease") association p(HGNC:IL18)
pubmed:27288790 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:CXCL10)
pubmed:27288790 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:TGFB1)
pubmed:27288790 path(MESH:"Alzheimer Disease") positiveCorrelation bp(GO:"MAPK cascade")
pubmed:27288790 path(MESH:"Alzheimer Disease") positiveCorrelation a(CHEBI:pentosidine)
pubmed:27288790 path(MESH:"Alzheimer Disease") positiveCorrelation a(CONSO:GLAP)
pubmed:27288790 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:PTGS2)
pubmed:27288790 path(MESH:"Alzheimer Disease") positiveCorrelation m(MIRBASE:hsa-mir-146a)
pubmed:27288790 path(MESH:"Alzheimer Disease") positiveCorrelation m(MIRBASE:hsa-mir-155)
pubmed:25652642 path(MESH:"Alzheimer Disease") positiveCorrelation complex(a(GO:"NF-kappaB complex"), p(HGNC:RELA))
pubmed:25652642 path(MESH:"Alzheimer Disease") positiveCorrelation act(complex(GO:"NF-kappaB complex"))
pubmed:25652642 path(MESH:"Alzheimer Disease") positiveCorrelation complex(GO:"NF-kappaB complex")
pubmed:25652642 path(MESH:"Alzheimer Disease") positiveCorrelation complex(GO:"NF-kappaB complex")
pubmed:25652642 path(MESH:"Alzheimer Disease") positiveCorrelation a(MESH:"HLA-DR Antigens")
pubmed:25652642 path(MESH:"Alzheimer Disease") positiveCorrelation m(HGNC:MIR9-1)
pubmed:25652642 path(MESH:"Alzheimer Disease") positiveCorrelation m(HGNC:MIR34A)
pubmed:25652642 path(MESH:"Alzheimer Disease") positiveCorrelation m(HGNC:MIR125B1)
pubmed:25652642 path(MESH:"Alzheimer Disease") positiveCorrelation m(HGNC:MIR146A)
pubmed:24586483 path(MESH:"Alzheimer Disease") association m(HGNC:MIR146A)
pubmed:24586483 path(MESH:"Alzheimer Disease") association m(HGNC:MIR146A)
pubmed:25652642 path(MESH:"Alzheimer Disease") positiveCorrelation m(HGNC:MIR155)
pubmed:25652642 path(MESH:"Alzheimer Disease") positiveCorrelation m(HGNC:MIR339)
pubmed:10656250 path(MESH:"Alzheimer Disease") increases p(HGNC:BACE1)
pubmed:30444369 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:HSD17B10)
pubmed:30444369 path(MESH:"Alzheimer Disease") negativeCorrelation act(p(HGNC:PRDX2))
pubmed:30444369 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:PRDX2)
pubmed:30444369 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:CDK5)
pubmed:24653673 path(MESH:"Alzheimer Disease") association p(HGNC:CDK5)
pubmed:8282104 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:CDK5)
pubmed:30444369 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:SH3GL2)
pubmed:29196815 path(MESH:"Alzheimer Disease") isA path(MESH:"Neurodegenerative Diseases")
pubmed:24511233 path(MESH:"Alzheimer Disease") isA path(MESH:"Neurodegenerative Diseases")
pubmed:24590577 path(MESH:"Alzheimer Disease") isA path(MESH:"Neurodegenerative Diseases")
pubmed:18986241 path(MESH:"Alzheimer Disease") association path(MESH:"Neurodegenerative Diseases")
pubmed:29980653 path(MESH:"Alzheimer Disease") isA path(MESH:"Neurodegenerative Diseases")
pubmed:29196815 path(MESH:"Alzheimer Disease") decreases bp(GO:cognition)
pubmed:19126755 path(MESH:"Alzheimer Disease") negativeCorrelation bp(GO:cognition)
pubmed:19293145 path(MESH:"Alzheimer Disease") decreases bp(GO:cognition)
pubmed:24511233 path(MESH:"Alzheimer Disease") association bp(GO:cognition)
pubmed:24511233 path(MESH:"Alzheimer Disease") decreases bp(GO:cognition)
pubmed:24590577 path(MESH:"Alzheimer Disease") decreases bp(GO:cognition)
pubmed:11230871 path(MESH:"Alzheimer Disease") negativeCorrelation bp(GO:cognition)
pubmed:19721446 path(MESH:"Alzheimer Disease") decreases bp(GO:cognition)
pubmed:29196815 path(MESH:"Alzheimer Disease") increases bp(GO:"neuron apoptotic process")
pubmed:29196815 path(MESH:"Alzheimer Disease") positiveCorrelation path(MESH:"Plaque, Amyloid")
pubmed:19126755 path(MESH:"Alzheimer Disease") positiveCorrelation path(MESH:"Plaque, Amyloid")
pubmed:19293145 path(MESH:"Alzheimer Disease") positiveCorrelation path(MESH:"Plaque, Amyloid")
pubmed:19293145 path(MESH:"Alzheimer Disease") association path(MESH:"Plaque, Amyloid")
pubmed:24590577 path(MESH:"Alzheimer Disease") association path(MESH:"Plaque, Amyloid")
pubmed:25514383 path(MESH:"Alzheimer Disease") positiveCorrelation path(MESH:"Plaque, Amyloid")
pubmed:19721446 path(MESH:"Alzheimer Disease") increases path(MESH:"Plaque, Amyloid")
pubmed:29758300 path(MESH:"Alzheimer Disease") positiveCorrelation path(MESH:"Plaque, Amyloid")
pubmed:14556719 path(MESH:"Alzheimer Disease") increases path(MESH:"Plaque, Amyloid")
pubmed:22817713 path(MESH:"Alzheimer Disease") positiveCorrelation path(MESH:"Plaque, Amyloid")
pubmed:29196815 path(MESH:"Alzheimer Disease") positiveCorrelation a(MESH:"Amyloid beta-Peptides")
pubmed:22122372 path(MESH:"Alzheimer Disease") association a(MESH:"Amyloid beta-Peptides")
pubmed:29196815 path(MESH:"Alzheimer Disease") positiveCorrelation a(GO:"neurofibrillary tangle")
pubmed:28420982 path(MESH:"Alzheimer Disease") positiveCorrelation a(GO:"neurofibrillary tangle")
pubmed:22817713 path(MESH:"Alzheimer Disease") association a(GO:"neurofibrillary tangle")
pubmed:11089576 path(MESH:"Alzheimer Disease") positiveCorrelation a(GO:"neurofibrillary tangle")
pubmed:29196815 path(MESH:"Alzheimer Disease") positiveCorrelation a(CONSO:CONSO00074)
pubmed:29196815 path(MESH:"Alzheimer Disease") positiveCorrelation a(CONSO:CONSO00074)
pubmed:29196815 path(MESH:"Alzheimer Disease") negativeCorrelation a(CHEBI:"amyloid-beta polypeptide 42")
pubmed:19293145 path(MESH:"Alzheimer Disease") association a(CHEBI:"amyloid-beta polypeptide 42")
pubmed:29196815 path(MESH:"Alzheimer Disease") positiveCorrelation a(CONSO:CONSO00076)
pubmed:29196815 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:NGFR)
pubmed:21214928 path(MESH:"Alzheimer Disease") positiveCorrelation r(CONSO:CONSO00064)
pubmed:21214928 path(MESH:"Alzheimer Disease") positiveCorrelation p(CONSO:CONSO00065)
pubmed:22122372 path(MESH:"Alzheimer Disease") positiveCorrelation p(CONSO:CONSO00065)
pubmed:21214928 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:ADAM10)
pubmed:21214928 path(MESH:"Alzheimer Disease") negativeCorrelation act(p(HGNC:ADAM10))
pubmed:21214928 path(MESH:"Alzheimer Disease") negativeCorrelation p(CONSO:CONSO00067)
pubmed:22122372 path(MESH:"Alzheimer Disease") association bp(GO:"neurofibrillary tangle assembly")
pubmed:22122372 path(MESH:"Alzheimer Disease") association bp(GO:"neuron death")
pubmed:14970312 path(MESH:"Alzheimer Disease") increases bp(GO:"neuron death")
pubmed:19293145 path(MESH:"Alzheimer Disease") increases bp(GO:"neuron death")
pubmed:17009926 path(MESH:"Alzheimer Disease") positiveCorrelation bp(GO:"neuron death")
pubmed:17009926 path(MESH:"Alzheimer Disease") positiveCorrelation bp(GO:"neuron death")
pubmed:24590577 path(MESH:"Alzheimer Disease") increases bp(GO:"neuron death")
pubmed:25514383 path(MESH:"Alzheimer Disease") positiveCorrelation bp(GO:"neuron death")
pubmed:22040696 path(MESH:"Alzheimer Disease") increases bp(GO:"neuron death")
pubmed:28420982 path(MESH:"Alzheimer Disease") positiveCorrelation bp(GO:"neuron death")
pubmed:26631930 path(MESH:"Alzheimer Disease") positiveCorrelation bp(GO:"neuron death")
pubmed:22122372 path(MESH:"Alzheimer Disease") positiveCorrelation p(CONSO:CONSO00064)
pubmed:22110360 path(MESH:"Alzheimer Disease") association p(HGNC:DYRK1A)
pubmed:26136662 path(MESH:"Alzheimer Disease") association p(FPLX:Histone, pmod(go:0006473 ! "protein acetylation", Lys, 280))
pubmed:27041503 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT)
pubmed:3122646 path(MESH:"Alzheimer Disease") increases tloc(p(HGNC:MAPT), fromLoc(GO:axon), toLoc(GO:"cell body"))
pubmed:25514383 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT)
pubmed:29758300 path(MESH:"Alzheimer Disease") association p(HGNC:MAPT)
pubmed:14556719 path(MESH:"Alzheimer Disease") association p(HGNC:MAPT)
pubmed:24027553 path(MESH:"Alzheimer Disease") association p(HGNC:MAPT)
pubmed:24027553 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT)
pubmed:27574109 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT)
pubmed:27574109 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT)
pubmed:30126037 path(MESH:"Alzheimer Disease") association p(HGNC:MAPT)
pubmed:22419736 path(MESH:"Alzheimer Disease") causesNoChange p(HGNC:MAPT)
pubmed:25374103 path(MESH:"Alzheimer Disease") increases tloc(p(HGNC:MAPT), fromLoc(GO:axon), toLoc(GO:"somatodendritic compartment"))
pubmed:28420982 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT)
pubmed:28420982 path(MESH:"Alzheimer Disease") increases p(HGNC:MAPT)
pubmed:28420982 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT)
pubmed:26631930 path(MESH:"Alzheimer Disease") increases tloc(p(HGNC:MAPT), fromLoc(GO:axon), toLoc(MESH:"Dendritic Spines"))
pubmed:26631930 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT)
pubmed:20869593 path(MESH:"Alzheimer Disease") association p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation"))
pubmed:24653673 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation"))
pubmed:8282104 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation"))
pubmed:24027553 path(MESH:"Alzheimer Disease") regulates p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation"))
pubmed:29191965 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation"))
pubmed:29191965 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation"))
pubmed:29311797 path(MESH:"Alzheimer Disease") association p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation"))
pubmed:26458742 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation"))
pubmed:26631930 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation"))
pubmed:26631930 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation"))
pubmed:22817713 path(MESH:"Alzheimer Disease") increases p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation"))
pubmed:22710270 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:PSEN1, var("p.Glu280Ala"))
pubmed:22710270 path(MESH:"Alzheimer Disease") association g(HGNC:CD44)
pubmed:22710270 path(MESH:"Alzheimer Disease") positiveCorrelation g(DBSNP:rs187116)
pubmed:22710270 path(MESH:"Alzheimer Disease") association g(HGNC:NPHP1)
pubmed:22710270 path(MESH:"Alzheimer Disease") positiveCorrelation g(DBSNP:rs10173717)
pubmed:22710270 path(MESH:"Alzheimer Disease") association g(HGNC:CADPS2)
pubmed:22020111 path(MESH:"Alzheimer Disease") increases g(HGNC:CADPS2)
pubmed:22710270 path(MESH:"Alzheimer Disease") positiveCorrelation g(DBSNP:rs3757536)
pubmed:22710270 path(MESH:"Alzheimer Disease") association g(HGNC:GREM2)
pubmed:22710270 path(MESH:"Alzheimer Disease") positiveCorrelation g(DBSNP:rs12129547)
pubmed:21769591 path(MESH:"Alzheimer Disease") association p(HGNC:APOE)
pubmed:22159054 path(MESH:"Alzheimer Disease") association p(HGNC:APOE)
pubmed:18191876 path(MESH:"Alzheimer Disease") association p(HGNC:A2M, var("p.Val1000Ile"))
pubmed:18191876 path(MESH:"Alzheimer Disease") association g(DBSNP:rs669)
pubmed:18191876 path(MESH:"Alzheimer Disease") association g(DBSNP:rs669)
pubmed:18191876 path(MESH:"Alzheimer Disease") association p(HGNC:OLR1)
pubmed:18191876 path(MESH:"Alzheimer Disease") association p(HGNC:OLR1)
pubmed:20693622 path(MESH:"Alzheimer Disease") association p(HGNC:CYP46A1)
pubmed:20693622 path(MESH:"Alzheimer Disease") association g(DBSNP:rs8003602)
pubmed:20693622 path(MESH:"Alzheimer Disease") association g(DBSNP:rs3783320)
pubmed:19926167 path(MESH:"Alzheimer Disease") positiveCorrelation g(DBSNP:rs17571)
pubmed:21892414 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:CLU)
pubmed:22159054 path(MESH:"Alzheimer Disease") association p(HGNC:CLU)
pubmed:21892414 path(MESH:"Alzheimer Disease") positiveCorrelation g(DBSNP:rs9331888)
pubmed:22382309 path(MESH:"Alzheimer Disease") positiveCorrelation g(HGNC:CD33)
pubmed:22167654 path(MESH:"Alzheimer Disease") positiveCorrelation g(HGNC:CD33)
pubmed:21460841 path(MESH:"Alzheimer Disease") association g(HGNC:CD33)
pubmed:22382309 path(MESH:"Alzheimer Disease") positiveCorrelation g(DBSNP:rs3865444)
pubmed:21460841 path(MESH:"Alzheimer Disease") association g(DBSNP:rs3865444)
pubmed:22382309 path(MESH:"Alzheimer Disease") positiveCorrelation g(HGNC:MS4A6A)
pubmed:22382309 path(MESH:"Alzheimer Disease") positiveCorrelation g(DBSNP:rs610932)
pubmed:21460840 path(MESH:"Alzheimer Disease") association g(DBSNP:rs610932)
pubmed:22167654 path(MESH:"Alzheimer Disease") positiveCorrelation g(DBSNP:rs3826656)
pubmed:22167654 path(MESH:"Alzheimer Disease") positiveCorrelation g(HGNC:GOLM1)
pubmed:22167654 path(MESH:"Alzheimer Disease") positiveCorrelation g(DBSNP:rs10868366)
pubmed:22167654 path(MESH:"Alzheimer Disease") positiveCorrelation g(DBSNP:rs7019241)
pubmed:21285854 path(MESH:"Alzheimer Disease") association g(HGNC:GAB2)
pubmed:17553421 path(MESH:"Alzheimer Disease") association g(HGNC:GAB2)
pubmed:21285854 path(MESH:"Alzheimer Disease") association g(DBSNP:rs4945261)
pubmed:21285854 path(MESH:"Alzheimer Disease") association g(DBSNP:rs7101429)
pubmed:21285854 path(MESH:"Alzheimer Disease") association g(DBSNP:rs7115850)
pubmed:22159054 path(MESH:"Alzheimer Disease") association p(HGNC:NECTIN2)
pubmed:22159054 path(MESH:"Alzheimer Disease") association g(DBSNP:rs6859)
pubmed:22159054 path(MESH:"Alzheimer Disease") association p(HGNC:PICALM)
pubmed:29626319 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:PICALM)
pubmed:27260836 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:PICALM)
pubmed:22159054 path(MESH:"Alzheimer Disease") association p(HGNC:BIN1)
pubmed:29758300 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:BIN1)
pubmed:22159054 path(MESH:"Alzheimer Disease") association p(HGNC:EPHA1)
pubmed:22159054 path(MESH:"Alzheimer Disease") association p(HGNC:MS4A7)
pubmed:22159054 path(MESH:"Alzheimer Disease") association p(HGNC:ABCA7)
pubmed:23556446 path(MESH:"Alzheimer Disease") association p(HGNC:ABCA7)
pubmed:22159054 path(MESH:"Alzheimer Disease") association p(HGNC:CD33)
pubmed:22005930 path(MESH:"Alzheimer Disease") association g(HGNC:SLC29A2)
pubmed:22005930 path(MESH:"Alzheimer Disease") association g(DBSNP:rs6834555)
pubmed:22005930 path(MESH:"Alzheimer Disease") association g(HGNC:VSNL1)
pubmed:22005930 path(MESH:"Alzheimer Disease") association g(DBSNP:rs4038131)
pubmed:21460840 path(MESH:"Alzheimer Disease") association g(HGNC:ABCA7)
pubmed:21460840 path(MESH:"Alzheimer Disease") association g(DBSNP:rs3764650)
pubmed:21460840 path(MESH:"Alzheimer Disease") association g(HGNC:MS4A1)
pubmed:18823527 path(MESH:"Alzheimer Disease") association g(HGNC:LRAT)
pubmed:18823527 path(MESH:"Alzheimer Disease") association g(DBSNP:rs201825)
pubmed:18823527 path(MESH:"Alzheimer Disease") association g(DBSNP:rs727153)
pubmed:19734902 path(MESH:"Alzheimer Disease") association g(HGNC:PICALM)
pubmed:21627779 path(MESH:"Alzheimer Disease") association g(HGNC:PICALM)
pubmed:21460841 path(MESH:"Alzheimer Disease") association g(HGNC:PICALM)
pubmed:21379329 path(MESH:"Alzheimer Disease") association g(HGNC:PICALM)
pubmed:19734902 path(MESH:"Alzheimer Disease") association g(DBSNP:rs3851179)
pubmed:21379329 path(MESH:"Alzheimer Disease") association g(DBSNP:rs3851179)
pubmed:19734902 path(MESH:"Alzheimer Disease") association g(HGNC:APOE)
pubmed:19734903 path(MESH:"Alzheimer Disease") association g(HGNC:APOE)
pubmed:20460622 path(MESH:"Alzheimer Disease") association g(HGNC:APOE)
pubmed:20885792 path(MESH:"Alzheimer Disease") association g(HGNC:APOE)
pubmed:17474819 path(MESH:"Alzheimer Disease") association g(HGNC:APOE)
pubmed:21123754 path(MESH:"Alzheimer Disease") association g(HGNC:APOE)
pubmed:10936883 path(MESH:"Alzheimer Disease") association g(HGNC:APOE)
pubmed:19293145 path(MESH:"Alzheimer Disease") positiveCorrelation g(HGNC:APOE)
pubmed:19734902 path(MESH:"Alzheimer Disease") association g(DBSNP:rs2075650)
pubmed:20460622 path(MESH:"Alzheimer Disease") association g(DBSNP:rs2075650)
pubmed:20061627 path(MESH:"Alzheimer Disease") association g(DBSNP:rs2075650)
pubmed:20885792 path(MESH:"Alzheimer Disease") association g(DBSNP:rs2075650)
pubmed:21123754 path(MESH:"Alzheimer Disease") association g(DBSNP:rs2075650)
pubmed:19734902 path(MESH:"Alzheimer Disease") association g(HGNC:CLU)
pubmed:19734903 path(MESH:"Alzheimer Disease") association g(HGNC:CLU)
pubmed:21627779 path(MESH:"Alzheimer Disease") association g(HGNC:CLU)
pubmed:21460841 path(MESH:"Alzheimer Disease") association g(HGNC:CLU)
pubmed:21379329 path(MESH:"Alzheimer Disease") association g(HGNC:CLU)
pubmed:" 26517285" path(MESH:"Alzheimer Disease") increases g(HGNC:CLU)
pubmed:19734902 path(MESH:"Alzheimer Disease") association g(DBSNP:rs11136000)
pubmed:19734903 path(MESH:"Alzheimer Disease") association g(DBSNP:rs11136000)
pubmed:21379329 path(MESH:"Alzheimer Disease") association g(DBSNP:rs11136000)
pubmed:21543606 path(MESH:"Alzheimer Disease") association g(DBSNP:rs11136000)
pubmed:19734903 path(MESH:"Alzheimer Disease") association g(DBSNP:rs6656401)
pubmed:19136949 path(MESH:"Alzheimer Disease") association g(HGNC:PCDH11X)
pubmed:19136949 path(MESH:"Alzheimer Disease") association g(DBSNP:rs5984894)
pubmed:19118814 path(MESH:"Alzheimer Disease") association g(HGNC:FAM13B)
pubmed:19118814 path(MESH:"Alzheimer Disease") association g(DBSNP:rs11610206)
pubmed:18976728 path(MESH:"Alzheimer Disease") association g(DBSNP:rs11159647)
pubmed:18976728 path(MESH:"Alzheimer Disease") association g(DBSNP:rs4420638)
pubmed:17474819 path(MESH:"Alzheimer Disease") association g(DBSNP:rs4420638)
pubmed:17975299 path(MESH:"Alzheimer Disease") association g(HGNC:SORL1)
pubmed:22005931 path(MESH:"Alzheimer Disease") association g(HGNC:DCHS2)
pubmed:22005931 path(MESH:"Alzheimer Disease") association g(DBSNP:rs1466662)
pubmed:21627779 path(MESH:"Alzheimer Disease") association g(HGNC:BIN1)
pubmed:21460841 path(MESH:"Alzheimer Disease") association g(HGNC:BIN1)
pubmed:21390209 path(MESH:"Alzheimer Disease") association g(HGNC:BIN1)
pubmed:21379329 path(MESH:"Alzheimer Disease") association g(HGNC:BIN1)
pubmed:21627779 path(MESH:"Alzheimer Disease") association g(DBSNP:rs744373)
pubmed:21390209 path(MESH:"Alzheimer Disease") association g(DBSNP:rs744373)
pubmed:21627779 path(MESH:"Alzheimer Disease") association g(DBSNP:rs569214)
pubmed:21627779 path(MESH:"Alzheimer Disease") association g(DBSNP:rs536841)
pubmed:21627779 path(MESH:"Alzheimer Disease") association g(DBSNP:rs1562990)
pubmed:20061627 path(MESH:"Alzheimer Disease") association g(HGNC:TOMM40)
pubmed:21123754 path(MESH:"Alzheimer Disease") association g(HGNC:TOMM40)
pubmed:21460841 path(MESH:"Alzheimer Disease") association g(DBSNP:rs5616655)
pubmed:21460841 path(MESH:"Alzheimer Disease") association g(HGNC:MS4A4A)
pubmed:21460841 path(MESH:"Alzheimer Disease") association g(DBSNP:rs4938933)
pubmed:21460841 path(MESH:"Alzheimer Disease") association g(DBSNP:rs7561528)
pubmed:21379329 path(MESH:"Alzheimer Disease") association g(DBSNP:rs7561528)
pubmed:21460841 path(MESH:"Alzheimer Disease") association g(HGNC:CR1)
pubmed:21460841 path(MESH:"Alzheimer Disease") association g(DBSNP:rs6701713)
pubmed:21460841 path(MESH:"Alzheimer Disease") association g(HGNC:CD2AP)
pubmed:21460841 path(MESH:"Alzheimer Disease") association g(DBSNP:rs9349407)
pubmed:21460841 path(MESH:"Alzheimer Disease") association g(HGNC:EPHA1)
pubmed:21460841 path(MESH:"Alzheimer Disease") association g(DBSNP:rs11767557)
pubmed:21460841 path(MESH:"Alzheimer Disease") association g(DBSNP:rs1532278)
pubmed:21390209 path(MESH:"Alzheimer Disease") association g(DBSNP:rs12989701)
pubmed:21379329 path(MESH:"Alzheimer Disease") association g(HGNC:CELF2)
pubmed:21379329 path(MESH:"Alzheimer Disease") association g(DBSNP:rs201119)
pubmed:20885792 path(MESH:"Alzheimer Disease") association g(HGNC:MTHFD1L)
pubmed:20885792 path(MESH:"Alzheimer Disease") association g(DBSNP:rs11754661)
pubmed:17553421 path(MESH:"Alzheimer Disease") association g(DBSNP:rs2373115)
pubmed:21123754 path(MESH:"Alzheimer Disease") association g(DBSNP:rs429358)
pubmed:21123754 path(MESH:"Alzheimer Disease") association g(HGNC:EPC2)
pubmed:21123754 path(MESH:"Alzheimer Disease") association g(DBSNP:rs4499362)
pubmed:21123754 path(MESH:"Alzheimer Disease") association g(HGNC:CCDC134)
pubmed:21123754 path(MESH:"Alzheimer Disease") association g(DBSNP:rs7364180)
pubmed:23022416 path(MESH:"Alzheimer Disease") positiveCorrelation g(DBSNP:rs3818361)
pubmed:23022416 path(MESH:"Alzheimer Disease") association composite(g(DBSNP:rs3818361), g(DBSNP:rs429358))
pubmed:22236693 path(MESH:"Alzheimer Disease") negativeCorrelation g(DBSNP:rs2072446)
pubmed:22236693 path(MESH:"Alzheimer Disease") positiveCorrelation g(DBSNP:rs2072446)
pubmed:22236693 path(MESH:"Alzheimer Disease") positiveCorrelation g(DBSNP:rs741072)
pubmed:22236693 path(MESH:"Alzheimer Disease") negativeCorrelation g(DBSNP:rs734194)
pubmed:22236693 path(MESH:"Alzheimer Disease") negativeCorrelation g(DBSNP:rs734194)
pubmed:29183403 path(MESH:"Alzheimer Disease") negativeCorrelation g(DBSNP:rs142787485)
pubmed:29183403 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:RAB10)
pubmed:21709374 path(MESH:"Alzheimer Disease") association g(DBSNP:rs1050283)
pubmed:18191876 path(MESH:"Alzheimer Disease") association g(DBSNP:rs1050283)
pubmed:18191876 path(MESH:"Alzheimer Disease") association g(DBSNP:rs12316150)
pubmed:19660836 path(MESH:"Alzheimer Disease") negativeCorrelation g(DBSNP:rs4135263)
pubmed:19660836 path(MESH:"Alzheimer Disease") negativeCorrelation g(DBSNP:rs1151999)
pubmed:19660836 path(MESH:"Alzheimer Disease") negativeCorrelation g(DBSNP:rs709149)
pubmed:19660836 path(MESH:"Alzheimer Disease") negativeCorrelation g(DBSNP:rs709154)
pubmed:19660836 path(MESH:"Alzheimer Disease") association g(HGNC:PPARG)
pubmed:19660836 path(MESH:"Alzheimer Disease") negativeCorrelation g(HGNC:PPARG)
pubmed:21548758 path(MESH:"Alzheimer Disease") association g(HGNC:HNRNPA1)
pubmed:24162737 path(MESH:"Alzheimer Disease") association g(HGNC:SQSTM1)
pubmed:22005930 path(MESH:"Alzheimer Disease") association g(HGNC:STK11)
pubmed:21390209 path(MESH:"Alzheimer Disease") association g(HGNC:AGRN)
pubmed:22020111 path(MESH:"Alzheimer Disease") increases g(HGNC:AGRN)
pubmed:19734902 path(MESH:"Alzheimer Disease") association g(HGNC:MIR146A)
pubmed:24586483 path(MESH:"Alzheimer Disease") association g(HGNC:MIR146A)
pubmed:19734902 path(MESH:"Alzheimer Disease") association g(HGNC:CSF3R)
pubmed:19734902 path(MESH:"Alzheimer Disease") association g(HGNC:DAB2)
pubmed:19734902 path(MESH:"Alzheimer Disease") association g(HGNC:DAB1)
pubmed:19734902 path(MESH:"Alzheimer Disease") association g(HGNC:BTBD3)
pubmed:19734902 path(MESH:"Alzheimer Disease") association g(HGNC:SKAP2)
pubmed:19734902 path(MESH:"Alzheimer Disease") association g(HGNC:NAV3)
pubmed:19734902 path(MESH:"Alzheimer Disease") association g(HGNC:MKI67)
pubmed:19734902 path(MESH:"Alzheimer Disease") association g(HGNC:ANXA1)
pubmed:19734902 path(MESH:"Alzheimer Disease") association g(HGNC:SPTLC1)
pubmed:19734902 path(MESH:"Alzheimer Disease") association g(HGNC:GRIN3A)
pubmed:19734902 path(MESH:"Alzheimer Disease") association g(HGNC:STIM2)
pubmed:19734902 path(MESH:"Alzheimer Disease") association g(HGNC:GRIK2)
pubmed:19734902 path(MESH:"Alzheimer Disease") association g(HGNC:ROBO2)
pubmed:19734902 path(MESH:"Alzheimer Disease") association g(HGNC:RYR2)
pubmed:19734902 path(MESH:"Alzheimer Disease") association g(HGNC:FOXO3)
pubmed:19734902 path(MESH:"Alzheimer Disease") association g(HGNC:SLC25A21)
pubmed:19734902 path(MESH:"Alzheimer Disease") association g(HGNC:RELN)
pubmed:19734902 path(MESH:"Alzheimer Disease") association g(HGNC:GRIK4)
pubmed:19734902 path(MESH:"Alzheimer Disease") association g(HGNC:APBA1)
pubmed:19734902 path(MESH:"Alzheimer Disease") association g(HGNC:RYR3)
pubmed:19734902 path(MESH:"Alzheimer Disease") association g(HGNC:ATP2A3)
pubmed:23535033 path(MESH:"Alzheimer Disease") association g(HGNC:CAMK4)
pubmed:23535033 path(MESH:"Alzheimer Disease") association g(HGNC:CYCS)
pubmed:22107728 path(MESH:"Alzheimer Disease") positiveCorrelation g(DBSNP:rs4646953)
pubmed:23279143 path(MESH:"Alzheimer Disease") association p(HGNC:SORCS1)
pubmed:23279143 path(MESH:"Alzheimer Disease") association g(DBSNP:rs7907690)
pubmed:23279143 path(MESH:"Alzheimer Disease") association g(DBSNP:rs7907690)
pubmed:23279143 path(MESH:"Alzheimer Disease") association g(DBSNP:rs601883)
pubmed:23279143 path(MESH:"Alzheimer Disease") association g(DBSNP:rs17277986)
pubmed:23279143 path(MESH:"Alzheimer Disease") association g(DBSNP:rs2900717)
pubmed:23279143 path(MESH:"Alzheimer Disease") association g(DBSNP:rs10884399)
pubmed:23279143 path(MESH:"Alzheimer Disease") association g(DBSNP:rs11193170)
pubmed:23279143 path(MESH:"Alzheimer Disease") association g(DBSNP:rs4918280)
pubmed:23279143 path(MESH:"Alzheimer Disease") association g(DBSNP:rs600879)
pubmed:23403532 path(MESH:"Alzheimer Disease") association complex(p(HGNC:NRXN1), p(INTERPRO:Neuroligin))
pubmed:23403532 path(MESH:"Alzheimer Disease") association complex(p(HGNC:NRXN2), p(INTERPRO:Neuroligin))
pubmed:23403532 path(MESH:"Alzheimer Disease") association complex(p(HGNC:NRXN3), p(INTERPRO:Neuroligin))
pubmed:21036197 path(MESH:"Alzheimer Disease") association g(DBSNP:rs411280)
pubmed:24586483 path(MESH:"Alzheimer Disease") positiveCorrelation g(DBSNP:rs57095329)
pubmed:25038421 path(MESH:"Alzheimer Disease") association g(DBSNP:rs998382)
pubmed:25038421 path(MESH:"Alzheimer Disease") association g(DBSNP:rs2424913)
pubmed:22691691 path(MESH:"Alzheimer Disease") association p(HGNC:DRD4)
pubmed:" 26517285" path(MESH:"Alzheimer Disease") negativeCorrelation bp(GO:"microglial cell activation")
pubmed:28877763 path(MESH:"Alzheimer Disease") increases bp(GO:"microglial cell activation")
pubmed:25687773 path(MESH:"Alzheimer Disease") association g(DBSNP:rs393152)
pubmed:25687773 path(MESH:"Alzheimer Disease") association g(DBSNP:rs393152)
pubmed:25687773 path(MESH:"Alzheimer Disease") association path(MESH:Atrophy)
pubmed:18986241 path(MESH:"Alzheimer Disease") increases path(MESH:Atrophy)
pubmed:26195256 path(MESH:"Alzheimer Disease") positiveCorrelation path(MESH:Atrophy)
pubmed:26195256 path(MESH:"Alzheimer Disease") decreases path(MESH:Atrophy)
pubmed:19419557 path(MESH:"Alzheimer Disease") decreases p(HGNC:GRIN1)
pubmed:19419557 path(MESH:"Alzheimer Disease") decreases p(HGNC:GRIN2A)
pubmed:19419557 path(MESH:"Alzheimer Disease") decreases p(HGNC:GRIN2B)
pubmed:19419557 path(MESH:"Alzheimer Disease") association p(HGNC:CALHM1, var("p.Pro86Leu"))
pubmed:23556446 path(MESH:"Alzheimer Disease") association p(HGNCGENEFAMILY:"ATP binding cassette subfamily A")
pubmed:23556446 path(MESH:"Alzheimer Disease") association g(DBSNP:rs3752246)
pubmed:23556446 path(MESH:"Alzheimer Disease") association g(DBSNP:rs3740066)
pubmed:23556446 path(MESH:"Alzheimer Disease") association p(HGNC:ABCC2)
pubmed:23556446 path(MESH:"Alzheimer Disease") association p(HGNC:ABCC2, var("p.Cys3972Thr"))
pubmed:20100581 path(MESH:"Alzheimer Disease") association a(NIFT:"Grey matter volume")
pubmed:20100581 path(MESH:"Alzheimer Disease") association p(HGNC:NXPH1)
pubmed:16151770 path(MESH:"Alzheimer Disease") negativeCorrelation a(NIFT:"Cerebral blood flow")
pubmed:23300102 path(MESH:"Alzheimer Disease") negativeCorrelation a(NIFT:"Cerebral blood flow")
pubmed:23300102 path(MESH:"Alzheimer Disease") negativeCorrelation bp(GO:"glucose metabolic process")
pubmed:26195256 path(MESH:"Alzheimer Disease") decreases bp(GO:"glucose metabolic process")
pubmed:26836182 path(MESH:"Alzheimer Disease") positiveCorrelation path(CONSO:neuroinflammation)
pubmed:22550605 path(MESH:"Alzheimer Disease") association p(HGNC:TOMM40, var("?"))
pubmed:26996954 path(MESH:"Alzheimer Disease") increases p(HGNC:APP, frag("672_713"))
pubmed:14970312 path(MESH:"Alzheimer Disease") increases p(HGNC:APP, frag("672_713"))
pubmed:21543606 path(MESH:"Alzheimer Disease") decreases a(NIFT:"White matter")
pubmed:14970312 path(MESH:"Alzheimer Disease") association bp(MESH:"Oxidative Stress")
pubmed:22020111 path(MESH:"Alzheimer Disease") positiveCorrelation bp(MESH:"Oxidative Stress")
pubmed:14970312 path(MESH:"Alzheimer Disease") association bp(GO:"sphingolipid metabolic process")
pubmed:14970312 path(MESH:"Alzheimer Disease") association bp(GO:"cholesterol metabolic process")
pubmed:30061532 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(CONSO:hyperphosphorylation))
pubmed:30145931 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(CONSO:hyperphosphorylation))
pubmed:17403556 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(CONSO:hyperphosphorylation))
pubmed:25374103 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(CONSO:hyperphosphorylation))
pubmed:26631930 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(CONSO:hyperphosphorylation))
pubmed:24401760 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(CONSO:hyperphosphorylation))
pubmed:19126755 path(MESH:"Alzheimer Disease") negativeCorrelation p(CONSO:"alpha-4 beta-2 nAChR")
pubmed:19126755 path(MESH:"Alzheimer Disease") negativeCorrelation p(CONSO:"alpha-4 beta-2 nAChR")
pubmed:19293145 path(MESH:"Alzheimer Disease") association p(CONSO:"alpha-4 beta-2 nAChR")
pubmed:19721446 path(MESH:"Alzheimer Disease") decreases p(CONSO:"alpha-4 beta-2 nAChR")
pubmed:19126755 path(MESH:"Alzheimer Disease") negativeCorrelation act(p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits"))
pubmed:19126755 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits")
pubmed:19126755 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits")
pubmed:19293145 path(MESH:"Alzheimer Disease") decreases p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits")
pubmed:19293145 path(MESH:"Alzheimer Disease") decreases act(p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits"))
pubmed:19293145 path(MESH:"Alzheimer Disease") association act(p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits"))
pubmed:19293145 path(MESH:"Alzheimer Disease") decreases p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits")
pubmed:19293145 path(MESH:"Alzheimer Disease") increases p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits")
pubmed:24590577 path(MESH:"Alzheimer Disease") decreases p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits")
pubmed:19721446 path(MESH:"Alzheimer Disease") decreases p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits")
pubmed:19126755 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:CHRNA7)
pubmed:19293145 path(MESH:"Alzheimer Disease") association p(HGNC:CHRNA7)
pubmed:19293145 path(MESH:"Alzheimer Disease") decreases p(HGNC:CHRNA7)
pubmed:19293145 path(MESH:"Alzheimer Disease") increases p(HGNC:CHRNA7)
pubmed:19293145 path(MESH:"Alzheimer Disease") decreases p(HGNC:CHRNA7)
pubmed:19293145 path(MESH:"Alzheimer Disease") decreases p(HGNC:CHRNA7)
pubmed:11230871 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:CHRNA7)
pubmed:22040696 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:CHRNA7)
pubmed:29191965 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:CHRNA7)
pubmed:19126755 path(MESH:"Alzheimer Disease") positiveCorrelation path(MESH:Dementia)
pubmed:19293145 path(MESH:"Alzheimer Disease") association path(MESH:Dementia)
pubmed:24511233 path(MESH:"Alzheimer Disease") association path(MESH:Dementia)
pubmed:25514383 path(MESH:"Alzheimer Disease") association path(MESH:Dementia)
pubmed:21718217 path(MESH:"Alzheimer Disease") increases path(MESH:Dementia)
pubmed:14556719 path(MESH:"Alzheimer Disease") increases path(MESH:Dementia)
pubmed:19126755 path(MESH:"Alzheimer Disease") negativeCorrelation bp(GO:"synaptic transmission, cholinergic")
pubmed:24511233 path(MESH:"Alzheimer Disease") decreases bp(GO:"synaptic transmission, cholinergic")
pubmed:24511233 path(MESH:"Alzheimer Disease") decreases bp(GO:"synaptic transmission, cholinergic")
pubmed:26813123 path(MESH:"Alzheimer Disease") association bp(GO:"synaptic transmission, cholinergic")
pubmed:24590577 path(MESH:"Alzheimer Disease") decreases bp(GO:"synaptic transmission, cholinergic")
pubmed:19126755 path(MESH:"Alzheimer Disease") positiveCorrelation path(MESH:"Neurofibrillary Tangles")
pubmed:24590577 path(MESH:"Alzheimer Disease") association path(MESH:"Neurofibrillary Tangles")
pubmed:24027553 path(MESH:"Alzheimer Disease") positiveCorrelation path(MESH:"Neurofibrillary Tangles")
pubmed:19126755 path(MESH:"Alzheimer Disease") positiveCorrelation path(MESH:"Neurogenic Inflammation")
pubmed:19126755 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:CHRNA4)
pubmed:19293145 path(MESH:"Alzheimer Disease") decreases p(HGNC:CHRNA4)
pubmed:19293145 path(MESH:"Alzheimer Disease") decreases p(HGNC:CHRNA4)
pubmed:19293145 path(MESH:"Alzheimer Disease") decreases p(HGNC:CHRNA4)
pubmed:11230871 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:CHRNA4)
pubmed:19293145 path(MESH:"Alzheimer Disease") decreases bp(GO:memory)
pubmed:24511233 path(MESH:"Alzheimer Disease") decreases bp(GO:memory)
pubmed:24511233 path(MESH:"Alzheimer Disease") decreases bp(GO:memory)
pubmed:22040696 path(MESH:"Alzheimer Disease") decreases bp(GO:memory)
pubmed:19293145 path(MESH:"Alzheimer Disease") decreases path(MESH:"Psychomotor Performance")
pubmed:19293145 path(MESH:"Alzheimer Disease") association path(MESH:Death)
pubmed:19293145 path(MESH:"Alzheimer Disease") positiveCorrelation a(MESH:"Neurofibrillary Tangles")
pubmed:18986241 path(MESH:"Alzheimer Disease") association a(MESH:"Neurofibrillary Tangles")
pubmed:18986241 path(MESH:"Alzheimer Disease") increases a(MESH:"Neurofibrillary Tangles")
pubmed:14556719 path(MESH:"Alzheimer Disease") increases a(MESH:"Neurofibrillary Tangles")
pubmed:19293145 path(MESH:"Alzheimer Disease") association a(CONSO:"amyloid-beta aggregates")
pubmed:25514383 path(MESH:"Alzheimer Disease") positiveCorrelation a(CONSO:"amyloid-beta aggregates")
pubmed:26195256 path(MESH:"Alzheimer Disease") increases a(CONSO:"amyloid-beta aggregates")
pubmed:22817713 path(MESH:"Alzheimer Disease") positiveCorrelation a(CONSO:"amyloid-beta aggregates")
pubmed:19293145 path(MESH:"Alzheimer Disease") increases p(HGNC:BCHE)
pubmed:18986241 path(MESH:"Alzheimer Disease") increases act(p(HGNC:BCHE))
pubmed:19293145 path(MESH:"Alzheimer Disease") decreases act(p(HGNC:CHAT))
pubmed:19293145 path(MESH:"Alzheimer Disease") decreases act(p(HGNC:CHAT))
pubmed:26813123 path(MESH:"Alzheimer Disease") decreases act(p(HGNC:CHAT))
pubmed:24590577 path(MESH:"Alzheimer Disease") decreases p(HGNC:CHAT)
pubmed:25514383 path(MESH:"Alzheimer Disease") decreases act(p(HGNC:CHAT))
pubmed:18986241 path(MESH:"Alzheimer Disease") decreases p(HGNC:CHAT)
pubmed:19293145 path(MESH:"Alzheimer Disease") decreases act(a(MESH:"Cholinesterase Inhibitors"))
pubmed:19293145 path(MESH:"Alzheimer Disease") association g(HGNC:CHAT)
pubmed:19293145 path(MESH:"Alzheimer Disease") association g(HGNC:ACHE)
pubmed:19293145 path(MESH:"Alzheimer Disease") increases p(HGNC:FYN)
pubmed:19293145 path(MESH:"Alzheimer Disease") increases p(HGNC:FYN)
pubmed:19293145 path(MESH:"Alzheimer Disease") increases complex(p(HGNC:FYN), p(HGNC:MAPT))
pubmed:24653673 path(MESH:"Alzheimer Disease") positiveCorrelation complex(p(HGNC:FYN), p(HGNC:MAPT))
pubmed:19293145 path(MESH:"Alzheimer Disease") association act(p(HGNC:INS))
pubmed:19293145 path(MESH:"Alzheimer Disease") association bp(GO:"regulation of cytosolic calcium ion concentration")
pubmed:19293145 path(MESH:"Alzheimer Disease") association p(HGNC:PSEN1)
pubmed:21722302 path(MESH:"Alzheimer Disease") increases p(HGNC:PSEN1)
pubmed:19293145 path(MESH:"Alzheimer Disease") association bp(GO:learning)
pubmed:24511233 path(MESH:"Alzheimer Disease") decreases bp(GO:learning)
pubmed:24511233 path(MESH:"Alzheimer Disease") decreases bp(GO:learning)
pubmed:19293145 path(MESH:"Alzheimer Disease") association path(MESH:"Cognitive Dysfunction")
pubmed:24511233 path(MESH:"Alzheimer Disease") association path(MESH:"Cognitive Dysfunction")
pubmed:24511233 path(MESH:"Alzheimer Disease") association path(MESH:"Cognitive Dysfunction")
pubmed:26813123 path(MESH:"Alzheimer Disease") positiveCorrelation path(MESH:"Cognitive Dysfunction")
pubmed:27522251 path(MESH:"Alzheimer Disease") increases path(MESH:"Cognitive Dysfunction")
pubmed:19293145 path(MESH:"Alzheimer Disease") decreases a(MESH:"Cholinergic Neurons")
pubmed:19293145 path(MESH:"Alzheimer Disease") decreases a(MESH:"Cholinergic Neurons")
pubmed:19293145 path(MESH:"Alzheimer Disease") decreases a(MESH:"Cholinergic Neurons")
pubmed:24511233 path(MESH:"Alzheimer Disease") decreases a(MESH:"Cholinergic Neurons")
pubmed:26813123 path(MESH:"Alzheimer Disease") negativeCorrelation a(MESH:"Cholinergic Neurons")
pubmed:24590577 path(MESH:"Alzheimer Disease") decreases a(MESH:"Cholinergic Neurons")
pubmed:24590577 path(MESH:"Alzheimer Disease") decreases a(MESH:"Cholinergic Neurons")
pubmed:19293145 path(MESH:"Alzheimer Disease") decreases complex(p(HGNC:CHRNA4), p(HGNC:CHRNB2))
pubmed:19293145 path(MESH:"Alzheimer Disease") decreases act(complex(p(HGNC:CHRNA4), p(HGNC:CHRNB2)))
pubmed:21787755 path(MESH:"Alzheimer Disease") association complex(p(HGNC:CHRNA4), p(HGNC:CHRNB2))
pubmed:19293145 path(MESH:"Alzheimer Disease") decreases p(HGNC:CHRNA3)
pubmed:19293145 path(MESH:"Alzheimer Disease") decreases p(HGNC:CHRNA3)
pubmed:19293145 path(MESH:"Alzheimer Disease") decreases p(HGNC:CHRNA3)
pubmed:11230871 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:CHRNA3)
pubmed:11230871 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:CHRNA3)
pubmed:11230871 path(MESH:"Alzheimer Disease") causesNoChange p(HGNC:CHRNA3)
pubmed:19293145 path(MESH:"Alzheimer Disease") causesNoChange r(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits")
pubmed:19293145 path(MESH:"Alzheimer Disease") decreases p(HGNC:CHRNB4)
pubmed:19293145 path(MESH:"Alzheimer Disease") decreases p(HGNCGENEFAMILY:"Glutamate ionotropic receptor NMDA type subunits")
pubmed:19293145 path(MESH:"Alzheimer Disease") decreases p(HGNCGENEFAMILY:"Glutamate ionotropic receptor AMPA type subunits")
pubmed:19293145 path(MESH:"Alzheimer Disease") decreases p(HGNC:GABRB3)
pubmed:19293145 path(MESH:"Alzheimer Disease") causesNoChange p(MGI:Chrna7)
pubmed:25881725 path(MESH:"Alzheimer Disease") negativeCorrelation p(MGI:Chrna7)
pubmed:19293145 path(MESH:"Alzheimer Disease") causesNoChange p(MGI:Chrna4)
pubmed:24511233 path(MESH:"Alzheimer Disease") association path(MESH:"Psychotic Disorders")
pubmed:24511233 path(MESH:"Alzheimer Disease") association path(MESH:"Psychotic Disorders")
pubmed:24511233 path(MESH:"Alzheimer Disease") association path(MESH:"Psychotic Disorders")
pubmed:24511233 path(MESH:"Alzheimer Disease") increases path(MESH:Depression)
pubmed:26813123 path(MESH:"Alzheimer Disease") positiveCorrelation path(MESH:Depression)
pubmed:24511233 path(MESH:"Alzheimer Disease") increases path(MESH:Anxiety)
pubmed:24511233 path(MESH:"Alzheimer Disease") association bp(MESH:Aging)
pubmed:17009926 path(MESH:"Alzheimer Disease") association p(FPLX:CHRN)
pubmed:17009926 path(MESH:"Alzheimer Disease") negativeCorrelation act(p(FPLX:CHRN))
pubmed:17009926 path(MESH:"Alzheimer Disease") negativeCorrelation p(FPLX:CHRN)
pubmed:17009926 path(MESH:"Alzheimer Disease") negativeCorrelation p(FPLX:CHRN)
pubmed:25514383 path(MESH:"Alzheimer Disease") decreases p(FPLX:CHRN)
pubmed:11230871 path(MESH:"Alzheimer Disease") association p(FPLX:CHRN)
pubmed:11230871 path(MESH:"Alzheimer Disease") negativeCorrelation p(FPLX:CHRN)
pubmed:17009926 path(MESH:"Alzheimer Disease") association complex(a(CHEBI:"amyloid-beta polypeptide 42"), p(HGNC:CHRNA7))
pubmed:26813123 path(MESH:"Alzheimer Disease") increases deg(a(MESH:"Basal Nucleus of Meynert"))
pubmed:26813123 path(MESH:"Alzheimer Disease") negativeCorrelation a(MESH:"Basal Nucleus of Meynert")
pubmed:26813123 path(MESH:"Alzheimer Disease") positiveCorrelation path(MESH:Apathy)
pubmed:26813123 path(MESH:"Alzheimer Disease") negativeCorrelation a(CHEBI:rivastigmine)
pubmed:26813123 path(MESH:"Alzheimer Disease") negativeCorrelation complex(p(HGNC:CHRM1), p(INTERPRO:"G-protein alpha subunit, group Q"))
pubmed:24590577 path(MESH:"Alzheimer Disease") association p(HGNCGENEFAMILY:"Cholinergic receptors muscarinic")
pubmed:19721446 path(MESH:"Alzheimer Disease") decreases p(HGNCGENEFAMILY:"Cholinergic receptors muscarinic")
pubmed:25514383 path(MESH:"Alzheimer Disease") negativeCorrelation a(GO:synapse)
pubmed:22908190 path(MESH:"Alzheimer Disease") negativeCorrelation act(a(GO:synapse))
pubmed:22908190 path(MESH:"Alzheimer Disease") negativeCorrelation act(a(GO:synapse))
pubmed:25514383 path(MESH:"Alzheimer Disease") negativeCorrelation a(MESH:"White Matter")
pubmed:26195256 path(MESH:"Alzheimer Disease") association a(MESH:"White Matter")
pubmed:25514383 path(MESH:"Alzheimer Disease") negativeCorrelation a(HP:"cholinergic neuron")
pubmed:25514383 path(MESH:"Alzheimer Disease") decreases complex(a(CHEBI:acetylcholine), p(FPLX:CHRN))
pubmed:25514383 path(MESH:"Alzheimer Disease") decreases complex(a(CHEBI:acetylcholine), p(FPLX:CHRM))
pubmed:25514383 path(MESH:"Alzheimer Disease") decreases complex(a(CHEBI:nicotine), p(FPLX:CHRN))
pubmed:11230871 path(MESH:"Alzheimer Disease") decreases complex(a(CHEBI:nicotine), p(FPLX:CHRN))
pubmed:25514383 path(MESH:"Alzheimer Disease") decreases complex(a(CHEBI:nicotine), p(FPLX:CHRM))
pubmed:25514383 path(MESH:"Alzheimer Disease") decreases p(FPLX:CHRM)
pubmed:25514383 path(MESH:"Alzheimer Disease") positiveCorrelation complex(p(HGNC:CHRNA7), p(HGNC:FLNA))
pubmed:21718217 path(MESH:"Alzheimer Disease") positiveCorrelation g(CONSO:CONSO00030)
pubmed:21718217 path(MESH:"Alzheimer Disease") association g(CONSO:CONSO00030)
pubmed:21718217 path(MESH:"Alzheimer Disease") positiveCorrelation r(HGNC:ARG1)
pubmed:21718217 path(MESH:"Alzheimer Disease") positiveCorrelation r(HGNC:CHI3L1)
pubmed:18986241 path(MESH:"Alzheimer Disease") decreases path(MESH:Memory)
pubmed:18986241 path(MESH:"Alzheimer Disease") decreases path(MESH:Cognition)
pubmed:18986241 path(MESH:"Alzheimer Disease") association path(MESH:"Behavioral Symptoms")
pubmed:18986241 path(MESH:"Alzheimer Disease") association path(CONSO:aMCI)
pubmed:18986241 path(MESH:"Alzheimer Disease") decreases path(MESH:"Cholinergic Neurons")
pubmed:18986241 path(MESH:"Alzheimer Disease") association path(MESH:"Cholinergic Neurons")
pubmed:18986241 path(MESH:"Alzheimer Disease") decreases path(MESH:"Cholinergic Neurons")
pubmed:18986241 path(MESH:"Alzheimer Disease") causesNoChange p(HGNC:SLC18A3)
pubmed:18986241 path(MESH:"Alzheimer Disease") increases a(MESH:"pro-nerve growth factor, human")
pubmed:18986241 path(MESH:"Alzheimer Disease") decreases p(HGNC:NTRK1)
pubmed:18986241 path(MESH:"Alzheimer Disease") increases p(HGNC:NGF)
pubmed:18986241 path(MESH:"Alzheimer Disease") association p(HGNC:SORT1)
pubmed:18986241 path(MESH:"Alzheimer Disease") decreases bp(GO:"nerve growth factor processing")
pubmed:18986241 path(MESH:"Alzheimer Disease") increases act(p(HGNC:MMP9))
pubmed:18986241 path(MESH:"Alzheimer Disease") decreases g(HGNC:NTRK1)
pubmed:18986241 path(MESH:"Alzheimer Disease") decreases g(HGNC:NTRK2)
pubmed:18986241 path(MESH:"Alzheimer Disease") decreases g(HGNC:NTRK3)
pubmed:18986241 path(MESH:"Alzheimer Disease") increases g(HGNC:NGFR)
pubmed:18986241 path(MESH:"Alzheimer Disease") causesNoChange r(HGNC:CHAT)
pubmed:18986241 path(MESH:"Alzheimer Disease") increases r(HGNC:CHRNA7)
pubmed:18986241 path(MESH:"Alzheimer Disease") increases r(HGNC:CHRNA7)
pubmed:11230871 path(MESH:"Alzheimer Disease") positiveCorrelation r(HGNC:CHRNA7)
pubmed:18986241 path(MESH:"Alzheimer Disease") causesNoChange r(HGNC:CHRM1)
pubmed:18986241 path(MESH:"Alzheimer Disease") decreases r(HGNC:SYP)
pubmed:18986241 path(MESH:"Alzheimer Disease") decreases r(HGNCGENEFAMILY:Synaptotagmins)
pubmed:18986241 path(MESH:"Alzheimer Disease") causesNoChange r(HGNC:SNAP29)
pubmed:18986241 path(MESH:"Alzheimer Disease") causesNoChange r(HGNC:APP)
pubmed:18986241 path(MESH:"Alzheimer Disease") causesNoChange r(HGNC:NOTCH1)
pubmed:18986241 path(MESH:"Alzheimer Disease") increases r(HGNC:CTSD)
pubmed:18986241 path(MESH:"Alzheimer Disease") decreases r(HGNC:PPP1CA)
pubmed:18986241 path(MESH:"Alzheimer Disease") decreases r(HGNC:PPP1CC)
pubmed:18986241 path(MESH:"Alzheimer Disease") causesNoChange r(HGNC:MAPT)
pubmed:18986241 path(MESH:"Alzheimer Disease") decreases p(CONSO:"3R tau")
pubmed:27574109 path(MESH:"Alzheimer Disease") positiveCorrelation p(CONSO:"3R tau")
pubmed:26631930 path(MESH:"Alzheimer Disease") positiveCorrelation p(CONSO:"3R tau")
pubmed:11230871 path(MESH:"Alzheimer Disease") negativeCorrelation complex(CONSO:"alpha-4-containing nAChR")
pubmed:11230871 path(MESH:"Alzheimer Disease") causesNoChange complex(CONSO:"alpha-7-containing nAChR")
pubmed:11230871 path(MESH:"Alzheimer Disease") negativeCorrelation complex(CONSO:"alpha-7-containing nAChR")
pubmed:11230871 path(MESH:"Alzheimer Disease") causesNoChange r(HGNC:CHRNA3)
pubmed:11230871 path(MESH:"Alzheimer Disease") causesNoChange r(HGNC:CHRNA4)
pubmed:11230871 path(MESH:"Alzheimer Disease") decreases complex(CONSO:"alpha-4 beta-2 nAChR")
pubmed:19721446 path(MESH:"Alzheimer Disease") decreases a(MESH:Neurons)
pubmed:19721446 path(MESH:"Alzheimer Disease") decreases path(MESH:"Memory, Episodic")
pubmed:26837465 path(MESH:"Alzheimer Disease") increases complex(p(HGNC:ESR1), p(HGNC:MAPT, pmod(CONSO:hyperphosphorylation)))
pubmed:28901280 path(MESH:"Alzheimer Disease") association p(MESH:"Receptors, Nicotinic")
pubmed:23178521 path(MESH:"Alzheimer Disease") increases p(MGI:Il6)
pubmed:23178521 path(MESH:"Alzheimer Disease") increases p(MGI:Tnf)
pubmed:23178521 path(MESH:"Alzheimer Disease") increases p(MGI:Stat3, pmod(go:0006468 ! "protein phosphorylation"))
pubmed:22020111 path(MESH:"Alzheimer Disease") positiveCorrelation a(CONSO:"protein aggregates")
pubmed:22020111 path(MESH:"Alzheimer Disease") increases g(HGNC:ANP32A)
pubmed:22020111 path(MESH:"Alzheimer Disease") increases g(HGNC:BAX)
pubmed:22020111 path(MESH:"Alzheimer Disease") increases g(HGNC:BCHE)
pubmed:22020111 path(MESH:"Alzheimer Disease") increases g(HGNC:BGN)
pubmed:22020111 path(MESH:"Alzheimer Disease") increases g(HGNC:BRCA1)
pubmed:22020111 path(MESH:"Alzheimer Disease") increases g(HGNC:CAPN1)
pubmed:22020111 path(MESH:"Alzheimer Disease") increases g(HGNC:CCNB1)
pubmed:22020111 path(MESH:"Alzheimer Disease") increases g(HGNC:CDK1)
pubmed:22020111 path(MESH:"Alzheimer Disease") increases g(HGNC:CDK2)
pubmed:22020111 path(MESH:"Alzheimer Disease") increases g(HGNC:CDKN2A)
pubmed:22020111 path(MESH:"Alzheimer Disease") increases g(HGNC:CXCR4)
pubmed:22020111 path(MESH:"Alzheimer Disease") increases g(HGNC:EIF4EBP1)
pubmed:22020111 path(MESH:"Alzheimer Disease") increases g(HGNC:FOLH1)
pubmed:22020111 path(MESH:"Alzheimer Disease") increases g(HGNC:HOMER1)
pubmed:22020111 path(MESH:"Alzheimer Disease") increases g(HGNC:HRH1)
pubmed:22020111 path(MESH:"Alzheimer Disease") increases g(HGNC:IGF2)
pubmed:22020111 path(MESH:"Alzheimer Disease") increases g(HGNC:IGFBP2)
pubmed:22020111 path(MESH:"Alzheimer Disease") increases g(HGNC:LDLR)
pubmed:22020111 path(MESH:"Alzheimer Disease") increases g(HGNC:MAOA)
pubmed:22020111 path(MESH:"Alzheimer Disease") increases g(HGNC:NEFH)
pubmed:22020111 path(MESH:"Alzheimer Disease") increases g(HGNC:NPDC1)
pubmed:22020111 path(MESH:"Alzheimer Disease") increases g(HGNC:NRGN)
pubmed:22020111 path(MESH:"Alzheimer Disease") increases g(HGNC:PREP)
pubmed:22020111 path(MESH:"Alzheimer Disease") increases g(HGNC:PROS1)
pubmed:22020111 path(MESH:"Alzheimer Disease") increases g(HGNC:PTGS1)
pubmed:22020111 path(MESH:"Alzheimer Disease") increases g(HGNC:SELENBP1)
pubmed:22020111 path(MESH:"Alzheimer Disease") increases g(HGNC:TAGLN)
pubmed:22020111 path(MESH:"Alzheimer Disease") increases g(HGNC:TGFB1)
pubmed:22020111 path(MESH:"Alzheimer Disease") increases g(HGNC:TUBB3)
pubmed:22020111 path(MESH:"Alzheimer Disease") increases g(HGNC:VKORC1)
pubmed:22020111 path(MESH:"Alzheimer Disease") decreases g(HGNC:CANX)
pubmed:22020111 path(MESH:"Alzheimer Disease") decreases g(HGNC:GCNT2)
pubmed:22020111 path(MESH:"Alzheimer Disease") decreases g(HGNC:IDE)
pubmed:22020111 path(MESH:"Alzheimer Disease") decreases g(HGNC:MMP1)
pubmed:22020111 path(MESH:"Alzheimer Disease") decreases g(HGNC:NFE2L2)
pubmed:22020111 path(MESH:"Alzheimer Disease") decreases g(HGNC:NR3C1)
pubmed:22020111 path(MESH:"Alzheimer Disease") decreases g(HGNC:PPARA)
pubmed:22020111 path(MESH:"Alzheimer Disease") decreases g(HGNC:SLC6A6)
pubmed:22020111 path(MESH:"Alzheimer Disease") decreases g(HGNC:SYVN1)
pubmed:22020111 path(MESH:"Alzheimer Disease") decreases g(HGNC:TSHZ1)
pubmed:22020111 path(MESH:"Alzheimer Disease") decreases g(HGNC:TXN)
pubmed:22020111 path(MESH:"Alzheimer Disease") decreases g(HGNC:ACLY)
pubmed:22020111 path(MESH:"Alzheimer Disease") decreases g(HGNC:ATAD2)
pubmed:22020111 path(MESH:"Alzheimer Disease") decreases g(HGNC:BECN1)
pubmed:22020111 path(MESH:"Alzheimer Disease") decreases g(HGNC:DHCR24)
pubmed:22020111 path(MESH:"Alzheimer Disease") decreases g(HGNC:FGF2)
pubmed:22020111 path(MESH:"Alzheimer Disease") decreases g(HGNC:HTRA1)
pubmed:22020111 path(MESH:"Alzheimer Disease") decreases g(HGNC:PRKCE)
pubmed:22020111 path(MESH:"Alzheimer Disease") decreases g(HGNC:PRKDC)
pubmed:22020111 path(MESH:"Alzheimer Disease") decreases g(HGNC:SCD)
pubmed:22020111 path(MESH:"Alzheimer Disease") decreases g(HGNC:TUBB)
pubmed:22020111 path(MESH:"Alzheimer Disease") decreases g(HGNC:UNG)
pubmed:22020111 path(MESH:"Alzheimer Disease") increases g(HGNC:ATP1A1)
pubmed:22020111 path(MESH:"Alzheimer Disease") increases g(HGNC:CTSD)
pubmed:22020111 path(MESH:"Alzheimer Disease") increases g(HGNC:GLRX)
pubmed:22020111 path(MESH:"Alzheimer Disease") positiveCorrelation g(HGNC:GLRX)
pubmed:22020111 path(MESH:"Alzheimer Disease") increases g(HGNC:HMOX1)
pubmed:22020111 path(MESH:"Alzheimer Disease") positiveCorrelation g(HGNC:HMOX1)
pubmed:22020111 path(MESH:"Alzheimer Disease") increases g(HGNC:IL6R)
pubmed:22020111 path(MESH:"Alzheimer Disease") increases g(HGNC:NPTX1)
pubmed:22020111 path(MESH:"Alzheimer Disease") increases g(HGNC:NQO1)
pubmed:22020111 path(MESH:"Alzheimer Disease") positiveCorrelation g(HGNC:NQO1)
pubmed:22020111 path(MESH:"Alzheimer Disease") increases g(HGNC:PHF1)
pubmed:22020111 path(MESH:"Alzheimer Disease") increases g(HGNC:PRKCD)
pubmed:22020111 path(MESH:"Alzheimer Disease") increases g(HGNC:PTGS2)
pubmed:22020111 path(MESH:"Alzheimer Disease") increases g(HGNC:RANBP9)
pubmed:22020111 path(MESH:"Alzheimer Disease") increases g(HGNC:SOD1)
pubmed:22020111 path(MESH:"Alzheimer Disease") positiveCorrelation g(HGNC:SOD1)
pubmed:30688256 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:PSEN1, var("?"))
pubmed:29758300 path(MESH:"Alzheimer Disease") association p(HGNC:PSEN1, var("?"))
pubmed:23454242 path(MESH:"Alzheimer Disease") increases p(HGNC:SET)
pubmed:24653673 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:SET)
pubmed:22299660 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:SET)
pubmed:23454242 path(MESH:"Alzheimer Disease") decreases act(p(FPLX:PPP2))
pubmed:22299660 path(MESH:"Alzheimer Disease") negativeCorrelation act(p(FPLX:PPP2))
pubmed:22299660 path(MESH:"Alzheimer Disease") negativeCorrelation act(p(FPLX:PPP2))
pubmed:24653673 path(MESH:"Alzheimer Disease") association p(HGNC:GSK3B)
pubmed:24653673 path(MESH:"Alzheimer Disease") association a(MESH:"Receptors, N-Methyl-D-Aspartate")
pubmed:24653673 path(MESH:"Alzheimer Disease") association p(HGNC:GRM5)
pubmed:24653673 path(MESH:"Alzheimer Disease") negativeCorrelation act(complex(GO:"protein phosphatase type 2A complex"))
pubmed:24653673 path(MESH:"Alzheimer Disease") positiveCorrelation complex(GO:"protein phosphatase type 2A complex")
pubmed:24653673 path(MESH:"Alzheimer Disease") negativeCorrelation act(complex(GO:"protein phosphatase type 2A complex"))
pubmed:24653673 path(MESH:"Alzheimer Disease") negativeCorrelation g(HGNC:PPP2CA)
pubmed:24653673 path(MESH:"Alzheimer Disease") negativeCorrelation r(HGNC:PPP2CA)
pubmed:22299660 path(MESH:"Alzheimer Disease") negativeCorrelation r(HGNC:PPP2CA)
pubmed:22299660 path(MESH:"Alzheimer Disease") causesNoChange r(HGNC:PPP2CA)
pubmed:24653673 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:PPP2CA)
pubmed:26631930 path(MESH:"Alzheimer Disease") negativeCorrelation act(p(HGNC:PPP2CA))
pubmed:24653673 path(MESH:"Alzheimer Disease") negativeCorrelation g(HGNC:PPP2CB)
pubmed:24653673 path(MESH:"Alzheimer Disease") negativeCorrelation r(HGNC:PPP2CB)
pubmed:22299660 path(MESH:"Alzheimer Disease") negativeCorrelation r(HGNC:PPP2CB)
pubmed:24653673 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:PPP2CB)
pubmed:24653673 path(MESH:"Alzheimer Disease") negativeCorrelation r(HGNC:PPP2R2C)
pubmed:24653673 path(MESH:"Alzheimer Disease") negativeCorrelation r(HGNC:PPP2R5E)
pubmed:24653673 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:PPP2R2A)
pubmed:22299660 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:PPP2R2A)
pubmed:24653673 path(MESH:"Alzheimer Disease") negativeCorrelation p(FPLX:PPP2, pmod(go:0006479 ! "protein methylation"))
pubmed:24653673 path(MESH:"Alzheimer Disease") negativeCorrelation p(FPLX:PPP2, pmod(go:0006479 ! "protein methylation"))
pubmed:24653673 path(MESH:"Alzheimer Disease") negativeCorrelation p(FPLX:PPP2, pmod(go:0006479 ! "protein methylation"))
pubmed:29281045 path(MESH:"Alzheimer Disease") decreases p(FPLX:PPP2, pmod(go:0006479 ! "protein methylation"))
pubmed:24653673 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:ANP32A)
pubmed:22299660 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:ANP32A)
pubmed:24653673 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:SET, frag("?"))
pubmed:24653673 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:PTPA)
pubmed:24653673 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Thr, 231))
pubmed:17403556 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Thr, 231))
pubmed:17403556 path(MESH:"Alzheimer Disease") increases p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Thr, 231))
pubmed:22253473 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Thr, 231))
pubmed:24653673 path(MESH:"Alzheimer Disease") negativeCorrelation complex(p(HGNC:PPP2CA), p(HGNC:PPP2R1A), p(HGNC:PPP2R2A))
pubmed:24653673 path(MESH:"Alzheimer Disease") negativeCorrelation complex(p(HGNC:PPP2CA), p(HGNC:PPP2R1A), p(HGNC:PPP2R2A))
pubmed:24653673 path(MESH:"Alzheimer Disease") negativeCorrelation complex(p(HGNC:PPP2CB), p(HGNC:PPP2R1A), p(HGNC:PPP2R2A))
pubmed:24653673 path(MESH:"Alzheimer Disease") negativeCorrelation complex(p(HGNC:PPP2CB), p(HGNC:PPP2R1A), p(HGNC:PPP2R2A))
pubmed:24653673 path(MESH:"Alzheimer Disease") negativeCorrelation complex(p(HGNC:MAPT), p(HGNC:PPP2CA), p(HGNC:PPP2R1A), p(HGNC:PPP2R2A))
pubmed:24653673 path(MESH:"Alzheimer Disease") negativeCorrelation complex(p(HGNC:MAPT), p(HGNC:PPP2CB), p(HGNC:PPP2R1A), p(HGNC:PPP2R2A))
pubmed:12428809 path(MESH:"Alzheimer Disease") association a(CONSO:"straight filaments")
pubmed:12428809 path(MESH:"Alzheimer Disease") positiveCorrelation p(CONSO:"4R tau")
pubmed:27574109 path(MESH:"Alzheimer Disease") positiveCorrelation p(CONSO:"4R tau")
pubmed:26631930 path(MESH:"Alzheimer Disease") positiveCorrelation p(CONSO:"4R tau")
pubmed:12428809 path(MESH:"Alzheimer Disease") negativeCorrelation bp(GO:"axonal transport")
pubmed:22908190 path(MESH:"Alzheimer Disease") negativeCorrelation bp(GO:"axonal transport")
pubmed:12428809 path(MESH:"Alzheimer Disease") association p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Ser, 396), pmod(go:0006468 ! "protein phosphorylation", Ser, 404))
pubmed:21882945 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Ser, 396), pmod(go:0006468 ! "protein phosphorylation", Ser, 404))
pubmed:22299660 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Ser, 198))
pubmed:23088643 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Ser, 198))
pubmed:22299660 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Ser, 199))
pubmed:26458742 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Ser, 199))
pubmed:23088643 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Ser, 199))
pubmed:22299660 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Ser, 202))
pubmed:29191965 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Ser, 202))
pubmed:23088643 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Ser, 202))
pubmed:22299660 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Ser, 396))
pubmed:22419736 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Ser, 396))
pubmed:28420982 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Ser, 396))
pubmed:26458742 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Ser, 396))
pubmed:22299660 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Ser, 404))
pubmed:22419736 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Ser, 404))
pubmed:26458742 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Ser, 404))
pubmed:22299660 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Ser, 422))
pubmed:29191965 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Ser, 422))
pubmed:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Ser, 422))
pubmed:27373205 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Ser, 422))
pubmed:23088643 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Ser, 422))
pubmed:22299660 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Ser, 262))
pubmed:29758300 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Ser, 262))
pubmed:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Ser, 262))
pubmed:22299660 path(MESH:"Alzheimer Disease") negativeCorrelation p(FPLX:PPP2C)
pubmed:22299660 path(MESH:"Alzheimer Disease") negativeCorrelation p(FPLX:PPP2C, pmod(go:0006479 ! "protein methylation", Leu, 309))
pubmed:22299660 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:ICMT)
pubmed:22299660 path(MESH:"Alzheimer Disease") positiveCorrelation p(FPLX:PPP2C, pmod(go:0006468 ! "protein phosphorylation", Tyr, 307))
pubmed:21722302 path(MESH:"Alzheimer Disease") association path(CONSO:Neurodegeneration)
pubmed:21722302 path(MESH:"Alzheimer Disease") association bp(CONSO:"protein aggregation")
pubmed:21722302 path(MESH:"Alzheimer Disease") association path(HP:"Senile plaques")
pubmed:21722302 path(MESH:"Alzheimer Disease") association path(MESH:Neurites)
pubmed:21722302 path(MESH:"Alzheimer Disease") association p(PFAM:Presenilin, var("?"))
pubmed:21722302 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:HSPA5)
pubmed:21722302 path(MESH:"Alzheimer Disease") association p(HGNC:XBP1)
pubmed:21722302 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:XBP1)
pubmed:21722302 path(MESH:"Alzheimer Disease") decreases bp(MESH:"Unfolded Protein Response")
pubmed:21722302 path(MESH:"Alzheimer Disease") association a(GO:autophagosome)
pubmed:29758300 path(MESH:"Alzheimer Disease") increases a(GO:autophagosome)
pubmed:22908190 path(MESH:"Alzheimer Disease") positiveCorrelation a(GO:autophagosome)
pubmed:18930136 path(MESH:"Alzheimer Disease") positiveCorrelation a(GO:autophagosome)
pubmed:18930136 path(MESH:"Alzheimer Disease") positiveCorrelation a(GO:autophagosome)
pubmed:21722302 path(MESH:"Alzheimer Disease") negativeCorrelation bp(GO:autophagy)
pubmed:29758300 path(MESH:"Alzheimer Disease") negativeCorrelation bp(GO:autophagy)
pubmed:22908190 path(MESH:"Alzheimer Disease") association bp(GO:autophagy)
pubmed:22908190 path(MESH:"Alzheimer Disease") association bp(GO:autophagy)
pubmed:25437566 path(MESH:"Alzheimer Disease") decreases p(HGNC:HSP90AB1)
pubmed:25437566 path(MESH:"Alzheimer Disease") decreases p(HGNC:HSPA8)
pubmed:25437566 path(MESH:"Alzheimer Disease") decreases p(HGNC:HSPA14)
pubmed:25437566 path(MESH:"Alzheimer Disease") decreases p(HGNC:TCP1)
pubmed:27491084 path(MESH:"Alzheimer Disease") decreases p(HGNCGENEFAMILY:"DNAJ (HSP40) heat shock proteins")
pubmed:27491084 path(MESH:"Alzheimer Disease") increases p(HGNC:HSPB1)
pubmed:27491084 path(MESH:"Alzheimer Disease") increases p(HGNC:CRYAB)
pubmed:27491084 path(MESH:"Alzheimer Disease") increases p(FPLX:HSPB)
pubmed:29758300 path(MESH:"Alzheimer Disease") negativeCorrelation bp(GO:macroautophagy)
pubmed:29758300 path(MESH:"Alzheimer Disease") negativeCorrelation bp(GO:macroautophagy)
pubmed:29758300 path(MESH:"Alzheimer Disease") negativeCorrelation bp(GO:macroautophagy)
pubmed:29758300 path(MESH:"Alzheimer Disease") negativeCorrelation bp(GO:macroautophagy)
pubmed:25784053 path(MESH:"Alzheimer Disease") negativeCorrelation bp(GO:macroautophagy)
pubmed:29758300 path(MESH:"Alzheimer Disease") increases complex(a(CONSO:"dystrophic neurite"), a(GO:autophagosome))
pubmed:29758300 path(MESH:"Alzheimer Disease") positiveCorrelation a(GO:autolysosome)
pubmed:23528736 path(MESH:"Alzheimer Disease") increases a(GO:autolysosome)
pubmed:23528736 path(MESH:"Alzheimer Disease") increases a(GO:autolysosome)
pubmed:29758300 path(MESH:"Alzheimer Disease") negativeCorrelation bp(GO:"lysosomal protein catabolic process")
pubmed:22908190 path(MESH:"Alzheimer Disease") negativeCorrelation bp(GO:"lysosomal protein catabolic process")
pubmed:23528736 path(MESH:"Alzheimer Disease") decreases bp(GO:"lysosomal protein catabolic process")
pubmed:29758300 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:BECN1)
pubmed:29758300 path(MESH:"Alzheimer Disease") decreases p(HGNC:BECN1)
pubmed:29758300 path(MESH:"Alzheimer Disease") increases a(GO:lysosome)
pubmed:22908190 path(MESH:"Alzheimer Disease") positiveCorrelation a(GO:lysosome)
pubmed:22908190 path(MESH:"Alzheimer Disease") negativeCorrelation act(a(GO:lysosome))
pubmed:29758300 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:SNCA)
pubmed:29758300 path(MESH:"Alzheimer Disease") negativeCorrelation bp(GO:endocytosis)
pubmed:22908190 path(MESH:"Alzheimer Disease") negativeCorrelation bp(GO:endocytosis)
pubmed:22908190 path(MESH:"Alzheimer Disease") negativeCorrelation bp(GO:endocytosis)
pubmed:29758300 path(MESH:"Alzheimer Disease") association a(CONSO:"alpha-synuclein aggregates")
pubmed:29758300 path(MESH:"Alzheimer Disease") positiveCorrelation a(CONSO:"alpha-synuclein aggregates")
pubmed:29758300 path(MESH:"Alzheimer Disease") association a(CHEBI:sphingolipid)
pubmed:29758300 path(MESH:"Alzheimer Disease") positiveCorrelation a(CHEBI:ceramide)
pubmed:29758300 path(MESH:"Alzheimer Disease") association p(HGNC:TFEB)
pubmed:29758300 path(MESH:"Alzheimer Disease") association p(HGNC:PICALM, var("?"))
pubmed:26195256 path(MESH:"Alzheimer Disease") association p(HGNC:PICALM, var("?"))
pubmed:29758300 path(MESH:"Alzheimer Disease") association p(HGNC:VPS35, var("?"))
pubmed:29758300 path(MESH:"Alzheimer Disease") association p(HGNC:SORL1)
pubmed:29758300 path(MESH:"Alzheimer Disease") increases bp(GO:mitophagy)
pubmed:14556719 path(MESH:"Alzheimer Disease") decreases bp(GO:"short-term memory")
pubmed:14556719 path(MESH:"Alzheimer Disease") negativeCorrelation act(p(HGNC:UBA1))
pubmed:14556719 path(MESH:"Alzheimer Disease") negativeCorrelation act(p(HGNC:UBA2))
pubmed:14556719 path(MESH:"Alzheimer Disease") negativeCorrelation bp(GO:"proteasome-mediated ubiquitin-dependent protein catabolic process")
pubmed:23528736 path(MESH:"Alzheimer Disease") negativeCorrelation bp(GO:"proteasome-mediated ubiquitin-dependent protein catabolic process")
pubmed:29626319 path(MESH:"Alzheimer Disease") decreases bp(GO:"proteasome-mediated ubiquitin-dependent protein catabolic process")
pubmed:22908190 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0016567 ! "protein ubiquitination"))
pubmed:22908190 path(MESH:"Alzheimer Disease") positiveCorrelation p(CONSO:"UBB+1")
pubmed:23528736 path(MESH:"Alzheimer Disease") positiveCorrelation p(CONSO:"UBB+1")
pubmed:22908190 path(MESH:"Alzheimer Disease") association p(HGNC:UCHL1)
pubmed:22908190 path(MESH:"Alzheimer Disease") association p(HGNC:UBQLN1)
pubmed:22908190 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:UBQLN1, var("?"))
pubmed:22908190 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:RAB7A)
pubmed:22908190 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:RAB5A)
pubmed:22908190 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:RAB4A)
pubmed:22908190 path(MESH:"Alzheimer Disease") positiveCorrelation a(CONSO:"dystrophic neurite")
pubmed:22908190 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:APP, var("?"))
pubmed:22908190 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:APP, var("?"))
pubmed:22908190 path(MESH:"Alzheimer Disease") association g(CONSO:"APOE e4")
pubmed:26195256 path(MESH:"Alzheimer Disease") positiveCorrelation g(CONSO:"APOE e4")
pubmed:25784053 path(MESH:"Alzheimer Disease") negativeCorrelation act(p(FPLX:Proteasome))
pubmed:8282104 path(MESH:"Alzheimer Disease") positiveCorrelation p(FPLX:ERK)
pubmed:8282104 path(MESH:"Alzheimer Disease") positiveCorrelation p(FPLX:GSK3)
pubmed:30116051 path(MESH:"Alzheimer Disease") decreases p(HGNC:SIRT1)
pubmed:30116051 path(MESH:"Alzheimer Disease") positiveCorrelation g(HGNC:PSEN1, var("?"))
pubmed:26195256 path(MESH:"Alzheimer Disease") association g(HGNC:PSEN1, var("?"))
pubmed:30116051 path(MESH:"Alzheimer Disease") negativeCorrelation a(CHEBI:"selenium(2+)")
pubmed:30116051 path(MESH:"Alzheimer Disease") increases act(p(HGNC:ABL1))
pubmed:30116051 path(MESH:"Alzheimer Disease") decreases p(HGNC:IDE)
pubmed:30116051 path(MESH:"Alzheimer Disease") decreases p(HGNC:MME)
pubmed:30116051 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:PLG)
pubmed:29024336 path(MESH:"Alzheimer Disease") increases path(MESH:"Proteostasis Deficiencies")
pubmed:29215007 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, var("?"))
pubmed:29980653 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, var("?"))
pubmed:24027553 path(MESH:"Alzheimer Disease") association p(HGNC:PIN1)
pubmed:24027553 path(MESH:"Alzheimer Disease") increases a(CHEBI:Thrombin, loc(MESH:Microvessels))
pubmed:24027553 path(MESH:"Alzheimer Disease") increases a(CHEBI:Thrombin, loc(MESH:"Cerebrospinal Fluid"))
pubmed:24027553 path(MESH:"Alzheimer Disease") positiveCorrelation a(CHEBI:Thrombin, loc(MESH:Neurons))
pubmed:24027553 path(MESH:"Alzheimer Disease") positiveCorrelation a(CHEBI:Thrombin, loc(MESH:Astrocytes))
pubmed:24027553 path(MESH:"Alzheimer Disease") association bp(CONSO:"APP processing")
pubmed:24027553 path(MESH:"Alzheimer Disease") association p(HGNC:HTRA1)
pubmed:24027553 path(MESH:"Alzheimer Disease") increases act(p(HGNC:CAPN2))
pubmed:24027553 path(MESH:"Alzheimer Disease") positiveCorrelation act(p(HGNC:CASP3))
pubmed:24027553 path(MESH:"Alzheimer Disease") positiveCorrelation act(p(HGNC:CASP6))
pubmed:24027553 path(MESH:"Alzheimer Disease") negativeCorrelation bp(GO:"proteasomal protein catabolic process")
pubmed:24027553 path(MESH:"Alzheimer Disease") increases complex(p(HGNC:MAPT), p(HGNCGENEFAMILY:Proteasome))
pubmed:24027553 path(MESH:"Alzheimer Disease") positiveCorrelation a(MESH:Autophagosomes)
pubmed:23528736 path(MESH:"Alzheimer Disease") increases a(MESH:Autophagosomes)
pubmed:23528736 path(MESH:"Alzheimer Disease") increases a(MESH:Autophagosomes)
pubmed:24027553 path(MESH:"Alzheimer Disease") positiveCorrelation a(MESH:Lysosomes)
pubmed:24027553 path(MESH:"Alzheimer Disease") decreases bp(MESH:Autophagy)
pubmed:27574109 path(MESH:"Alzheimer Disease") positiveCorrelation p(CONSO:"phosphatase-activating domain")
pubmed:21734277 path(MESH:"Alzheimer Disease") increases p(CONSO:"phosphatase-activating domain")
pubmed:21734277 path(MESH:"Alzheimer Disease") increases p(CONSO:"phosphatase-activating domain")
pubmed:27574109 path(MESH:"Alzheimer Disease") positiveCorrelation a(CONSO:"Tau oligomers")
pubmed:27574109 path(MESH:"Alzheimer Disease") positiveCorrelation a(CONSO:"Tau oligomers")
pubmed:25887395 path(MESH:"Alzheimer Disease") positiveCorrelation a(CONSO:"Tau oligomers")
pubmed:28420982 path(MESH:"Alzheimer Disease") positiveCorrelation a(CONSO:"Tau oligomers")
pubmed:26631930 path(MESH:"Alzheimer Disease") positiveCorrelation a(CONSO:"Tau oligomers")
pubmed:22817713 path(MESH:"Alzheimer Disease") increases a(CONSO:"Tau oligomers")
pubmed:27574109 path(MESH:"Alzheimer Disease") positiveCorrelation composite(p(CONSO:"phosphatase-activating domain"), p(HGNC:MAPT))
pubmed:23528736 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:UBB)
pubmed:23528736 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:UBC)
pubmed:23528736 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:UBA52)
pubmed:23528736 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:RPS27A)
pubmed:23528736 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNCGENEFAMILY:"Ubiquitin like modifier activating enzymes")
pubmed:23528736 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNCGENEFAMILY:"Ubiquitin conjugating enzymes E2")
pubmed:23528736 path(MESH:"Alzheimer Disease") association p(HGNC:STUB1)
pubmed:29311797 path(MESH:"Alzheimer Disease") association p(HGNC:STUB1)
pubmed:23528736 path(MESH:"Alzheimer Disease") association p(HGNC:PRKN)
pubmed:23528736 path(MESH:"Alzheimer Disease") association p(HGNC:RNF182)
pubmed:23528736 path(MESH:"Alzheimer Disease") association p(HGNC:UCHL1, var("?"))
pubmed:23528736 path(MESH:"Alzheimer Disease") decreases bp(MESH:Proteolysis)
pubmed:29988016 path(MESH:"Alzheimer Disease") positiveCorrelation a(CONSO:"Tau aggregates")
pubmed:27373205 path(MESH:"Alzheimer Disease") positiveCorrelation a(CONSO:"Tau aggregates")
pubmed:26631930 path(MESH:"Alzheimer Disease") positiveCorrelation a(CONSO:"Tau aggregates")
pubmed:22817713 path(MESH:"Alzheimer Disease") positiveCorrelation a(CONSO:"Tau aggregates")
pubmed:21882945 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Ser, 202), pmod(go:0006468 ! "protein phosphorylation", Thr, 205))
pubmed:21882945 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:BAG1)
pubmed:30126037 path(MESH:"Alzheimer Disease") association bp(MESH:"Cerebrovascular Circulation")
pubmed:22419736 path(MESH:"Alzheimer Disease") increases p(HGNC:AK1)
pubmed:22419736 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:AK1)
pubmed:22419736 path(MESH:"Alzheimer Disease") negativeCorrelation p(FPLX:AMPK, pmod(go:0006468 ! "protein phosphorylation", Thr, 172))
pubmed:29191965 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Thr, 205))
pubmed:30985105 path(MESH:"Alzheimer Disease") negativeCorrelation act(p(HGNC:OGT))
pubmed:30985105 path(MESH:"Alzheimer Disease") decreases p(HGNC:OGT)
pubmed:25374103 path(MESH:"Alzheimer Disease") decreases complex(a(GO:microtubule), p(HGNC:MAPT))
pubmed:25374103 path(MESH:"Alzheimer Disease") decreases p(HGNC:MAPT, pmod(CONSO:misfolded))
pubmed:28420982 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Thr, 181))
pubmed:29311797 path(MESH:"Alzheimer Disease") isA path(MESH:Tauopathies)
pubmed:26631930 path(MESH:"Alzheimer Disease") isA path(MESH:Tauopathies)
pubmed:29311797 path(MESH:"Alzheimer Disease") decreases p(HGNC:PPID)
pubmed:29311797 path(MESH:"Alzheimer Disease") increases p(HGNC:FKBP5)
pubmed:29311797 path(MESH:"Alzheimer Disease") decreases p(HGNC:FKBP4)
pubmed:29311797 path(MESH:"Alzheimer Disease") decreases act(p(HGNC:PPP5C))
pubmed:29311797 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:AHSA1)
pubmed:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Tyr, 18))
pubmed:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Ser, 68))
pubmed:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Thr, 69))
pubmed:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Thr, 71))
pubmed:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Ser, 113))
pubmed:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Thr, 123))
pubmed:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Thr, 153))
pubmed:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Thr, 175))
pubmed:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Thr, 184))
pubmed:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Ser, 185))
pubmed:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Ser, 191))
pubmed:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Tyr, 197))
pubmed:23088643 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Tyr, 197))
pubmed:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Ser, 208))
pubmed:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Ser, 210))
pubmed:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Ser, 214))
pubmed:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Ser, 237))
pubmed:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Ser, 238))
pubmed:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Ser, 258))
pubmed:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Ser, 289))
pubmed:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Ser, 356))
pubmed:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Tyr, 394))
pubmed:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Thr, 403))
pubmed:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Ser, 409))
pubmed:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Ser, 435))
pubmed:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Thr, 427))
pubmed:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Ser, 433))
pubmed:26195256 path(MESH:"Alzheimer Disease") association g(HGNC:PSEN2, var("?"))
pubmed:26195256 path(MESH:"Alzheimer Disease") association g(HGNC:APP, var("?"))
pubmed:26195256 path(MESH:"Alzheimer Disease") association p(HGNC:TREM2, var("?"))
pubmed:26195256 path(MESH:"Alzheimer Disease") association p(HGNC:CLU, var("?"))
pubmed:26195256 path(MESH:"Alzheimer Disease") negativeCorrelation a(MESH:"Cerebral Cortex")
pubmed:26195256 path(MESH:"Alzheimer Disease") positiveCorrelation a(MESH:"Cerebral Ventricles")
pubmed:26195256 path(MESH:"Alzheimer Disease") negativeCorrelation p(MESH:Neprilysin)
pubmed:26195256 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MMP2)
pubmed:26195256 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:LRP1)
pubmed:26195256 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:ABCB1)
pubmed:29626319 path(MESH:"Alzheimer Disease") decreases p(HGNC:ABCB1)
pubmed:26195256 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:AGER)
pubmed:26195256 path(MESH:"Alzheimer Disease") negativeCorrelation a(MESH:"Cerebrospinal Fluid")
pubmed:26195256 path(MESH:"Alzheimer Disease") negativeCorrelation act(p(HGNC:AQP1))
pubmed:26195256 path(MESH:"Alzheimer Disease") increases path(MESH:"Calcification, Physiologic")
pubmed:26195256 path(MESH:"Alzheimer Disease") increases path(MESH:Fibrosis)
pubmed:26631930 path(MESH:"Alzheimer Disease") decreases p(HGNC:MAPT, pmod(go:0006473 ! "protein acetylation", Lys, 259))
pubmed:26631930 path(MESH:"Alzheimer Disease") decreases p(HGNC:MAPT, pmod(go:0006473 ! "protein acetylation", Lys, 290))
pubmed:26631930 path(MESH:"Alzheimer Disease") decreases p(HGNC:MAPT, pmod(go:0006473 ! "protein acetylation", Lys, 321))
pubmed:26631930 path(MESH:"Alzheimer Disease") decreases p(HGNC:MAPT, pmod(go:0006473 ! "protein acetylation", Lys, 353))
pubmed:26631930 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006473 ! "protein acetylation", Lys, 280))
pubmed:29276758 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006473 ! "protein acetylation", Lys, 280))
pubmed:21427723 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006473 ! "protein acetylation", Lys, 280))
pubmed:26631930 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006473 ! "protein acetylation", Lys, 174))
pubmed:26631930 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(go:0006487 ! "protein N-linked glycosylation"))
pubmed:26631930 path(MESH:"Alzheimer Disease") decreases p(HGNC:MAPT, pmod(go:0006493 ! "protein O-linked glycosylation"))
pubmed:26631930 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(CONSO:nitration, Tyr, 18))
pubmed:26631930 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(CONSO:nitration, Tyr, 29))
pubmed:17050703 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(CONSO:nitration, Tyr, 29))
pubmed:26631930 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(CONSO:nitration, Tyr, 394))
pubmed:26631930 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:MAPT, pmod(go:0006479 ! "protein methylation"))
pubmed:26631930 path(MESH:"Alzheimer Disease") increases p(HGNC:MAPT, frag("?"))
pubmed:26631930 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, frag("26_230"))
pubmed:26631930 path(MESH:"Alzheimer Disease") increases a(CHEBI:"iron(0)")
pubmed:22817713 path(MESH:"Alzheimer Disease") association a(MESH:"Neuropil Threads")
pubmed:29626319 path(MESH:"Alzheimer Disease") decreases bp(GO:"lysosomal microautophagy")
pubmed:29626319 path(MESH:"Alzheimer Disease") positiveCorrelation act(p(HGNC:ACE))
pubmed:29626319 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:SERPINF2)
pubmed:29626319 path(MESH:"Alzheimer Disease") negativeCorrelation act(p(HGNC:SERPINF2))
pubmed:29626319 path(MESH:"Alzheimer Disease") decreases tloc(a(CHEBI:water), fromLoc(GO:"extracellular region"), toLoc(MESH:"Cerebrospinal Fluid"))
pubmed:25974414 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, var("p.Asp13*"))
pubmed:25974414 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, var("p.Asp25*"))
pubmed:25974414 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, var("p.Asp368*"))
pubmed:25974414 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, var("p.Glu391*"))
pubmed:25974414 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, var("p.Asp421*"))
pubmed:24869773 path(MESH:"Alzheimer Disease") association p(HGNC:MAPT, pmod(go:0006479 ! "protein methylation", Lys, 311))
pubmed:23531502 path(MESH:"Alzheimer Disease") positiveCorrelation act(a(CHEBI:acrolein))
pubmed:19251756 path(MESH:"Alzheimer Disease") negativeCorrelation bp(GO:"canonical glycolysis")
pubmed:19251756 path(MESH:"Alzheimer Disease") negativeCorrelation a(CHEBI:ATP)
pubmed:19251756 path(MESH:"Alzheimer Disease") positiveCorrelation p(INTERPRO:"Triosephosphate isomerase", pmod(go:0017014 ! "protein nitrosylation", Tyr, 164))
pubmed:19251756 path(MESH:"Alzheimer Disease") positiveCorrelation p(INTERPRO:"Triosephosphate isomerase", pmod(go:0017014 ! "protein nitrosylation", Tyr, 208))
pubmed:11738469 path(MESH:"Alzheimer Disease") positiveCorrelation act(p(ECCODE:2.3.2.13))
pubmed:8985134 path(MESH:"Alzheimer Disease") positiveCorrelation act(p(ECCODE:2.3.2.13))
pubmed:9099822 path(MESH:"Alzheimer Disease") increases act(p(HGNCGENEFAMILY:Transglutaminases))
pubmed:20096481 path(MESH:"Alzheimer Disease") positiveCorrelation g(DBSNP:rs2651206)
pubmed:21548880 path(MESH:"Alzheimer Disease") positiveCorrelation g(DBSNP:rs2651206)
pubmed:20096481 path(MESH:"Alzheimer Disease") positiveCorrelation g(DBSNP:rs10807287)
pubmed:20096481 path(MESH:"Alzheimer Disease") positiveCorrelation g(DBSNP:rs7764257)
pubmed:11943212 path(MESH:"Alzheimer Disease") positiveCorrelation path(CONSO:"granulovacuolar degeneration")
pubmed:23666762 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MARK4)
pubmed:23666762 path(MESH:"Alzheimer Disease") positiveCorrelation complex(p(HGNC:MAPT), p(HGNC:MARK4))
pubmed:28176663 path(MESH:"Alzheimer Disease") increases r(HGNC:GSK3B)
pubmed:26118667 path(MESH:"Alzheimer Disease") positiveCorrelation p(CONSO:"CDK5R1 p25")
pubmed:21910444 path(MESH:"Alzheimer Disease") increases p(HGNC:MAPK1)
pubmed:21910444 path(MESH:"Alzheimer Disease") increases p(HGNC:PRKCB)
pubmed:24401760 path(MESH:"Alzheimer Disease") increases p(HGNC:ITPKB)
pubmed:24401760 path(MESH:"Alzheimer Disease") positiveCorrelation path(CONSO:Astrogliosis)
pubmed:24401760 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:APP, frag("672_711"))
pubmed:29540553 path(MESH:"Alzheimer Disease") negativeCorrelation p(MGI:Sirt3)
pubmed:29559585 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:GAPDH, pmod(go:0017014 ! "protein nitrosylation"))
pubmed:21427723 path(MESH:"Alzheimer Disease") isA path(CONSO:"4R tauopathy")
pubmed:19732809 path(MESH:"Alzheimer Disease") negativeCorrelation p(MESH:Proteins, pmod(CONSO:O-GlcNAcylation))
pubmed:19732809 path(MESH:"Alzheimer Disease") positiveCorrelation g(HGNC:OGA, var("?"))
pubmed:27716675 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:SUMO1)
pubmed:19765634 path(MESH:"Alzheimer Disease") positiveCorrelation g(DBSNP:rs761059)
pubmed:29062069 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MID1)
pubmed:25001178 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:DUSP6)
pubmed:25001178 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:PPP1CA)
pubmed:29281045 path(MESH:"Alzheimer Disease") decreases p(HGNC:LCMT1)
pubmed:29281045 path(MESH:"Alzheimer Disease") increases p(HGNC:PPME1)
pubmed:24964035 path(MESH:"Alzheimer Disease") negativeCorrelation p(FPLX:SMAD)
pubmed:23157676 path(MESH:"Alzheimer Disease") positiveCorrelation p(CONSO:"cis p-tau")
pubmed:30837838 path(MESH:"Alzheimer Disease") association p(HGNC:TARDBP, pmod(go:0006468 ! "protein phosphorylation"), loc(GO:"inclusion body"))
pubmed:30837838 path(MESH:"Alzheimer Disease") association p(HGNC:TARDBP, pmod(go:0016567 ! "protein ubiquitination"), loc(GO:"inclusion body"))
pubmed:26091809 path(MESH:"Alzheimer Disease") increases path(MESH:Mortality)
pubmed:24561250 path(MESH:"Alzheimer Disease") association complex(GO:"NLRP3 inflammasome complex")
pubmed:24561250 path(MESH:"Alzheimer Disease") positiveCorrelation bp(GO:aging)
pubmed:24561250 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:PYCARD)
pubmed:24561250 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:NLRC4)
pubmed:24561250 path(MESH:"Alzheimer Disease") association complex(GO:"IPAF inflammasome complex")
pubmed:27314526 path(MESH:"Alzheimer Disease") association complex(GO:"inflammasome complex")
pubmed:27314526 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:P2RX7)
pubmed:25514383 bp(GO:"neuron cellular homeostasis") association complex(a(CHEBI:amyloid-beta), p(FPLX:CHRN))
pubmed:30988501 bp(GO:"neuron cellular homeostasis") increases p(HGNCGENEFAMILY:"Purinergic receptors P2X", loc(MESH:Microglia))
pubmed:30988501 bp(GO:"neuron cellular homeostasis") increases p(HGNCGENEFAMILY:"Glutamate metabotropic receptors", loc(MESH:Microglia))
pubmed:30046111 bp(GO:aging) decreases bp(GO:"cerebrospinal fluid circulation")
pubmed:30046111 bp(GO:aging) decreases act(a(HP:"interstitial fluid"))
pubmed:30046111 bp(GO:aging) increases a(CHEBI:amyloid-beta)
pubmed:29626319 bp(GO:aging) positiveCorrelation a(CHEBI:amyloid-beta)
pubmed:29421605 bp(GO:aging) positiveCorrelation a(CHEBI:amyloid-beta)
pubmed:30046111 bp(GO:aging) decreases act(a(MESH:"Lymphatic Vessels"))
pubmed:30046111 bp(GO:aging) negativeCorrelation act(a(MESH:"Lymphatic Vessels"))
pubmed:30046111 bp(GO:aging) decreases tloc(a(CHEBI:macromolecule), fromLoc(GO:"extracellular space"), toLoc(MESH:"Intracellular Space"))
pubmed:30046111 bp(GO:aging) association bp(GO:"immune response")
pubmed:30046111 bp(GO:aging) association bp(GO:"inflammatory response")
pubmed:30046111 bp(GO:aging) association bp(GO:"phospholipid metabolic process")
pubmed:30046111 bp(GO:aging) association bp(GO:"extracellular matrix organization")
pubmed:30046111 bp(GO:aging) association bp(GO:"cell adhesion")
pubmed:30046111 bp(GO:aging) association bp(GO:"endothelial tube morphogenesis")
pubmed:30046111 bp(GO:aging) decreases p(MGI:Cdk5r1)
pubmed:30046111 bp(GO:aging) decreases p(MGI:Adamts3)
pubmed:30046111 bp(GO:aging) decreases p(MGI:Fgfr3)
pubmed:26551702 bp(GO:aging) negativeCorrelation a(MESH:Glutathione)
pubmed:28760828 bp(GO:aging) increases p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation", Ser, 262), pmod(go:0006468 ! "protein phosphorylation", Ser, 356))
pubmed:21427723 bp(GO:aging) positiveCorrelation p(MGI:Mapt, pmod(go:0006473 ! "protein acetylation", Lys, 280))
pubmed:25031639 bp(GO:aging) decreases p(CONSO:"KXGS motif", pmod(go:0006473 ! "protein acetylation"))
pubmed:25031639 bp(GO:aging) increases p(CONSO:"KXGS motif", pmod(CONSO:hyperphosphorylation))
pubmed:25031639 bp(GO:aging) decreases p(HGNC:MAPT)
pubmed:30145931 bp(GO:aging) increases p(HGNC:MAPT)
pubmed:30145931 bp(GO:aging) decreases p(HGNC:MAPT)
pubmed:21882945 bp(GO:aging) negativeCorrelation deg(p(HGNC:MAPT))
pubmed:29238289 bp(GO:aging) increases p(HGNC:MAPT)
pubmed:29196815 bp(GO:aging) increases path(MESH:"Alzheimer Disease")
pubmed:24561250 bp(GO:aging) positiveCorrelation path(MESH:"Alzheimer Disease")
pubmed:29196815 bp(GO:aging) increases a(CONSO:CONSO00074)
pubmed:26979166 bp(GO:aging) negativeCorrelation bp(GO:"microglial cell mediated cytotoxicity")
pubmed:25514383 bp(GO:aging) association path(MESH:Dementia)
pubmed:27522251 bp(GO:aging) association p(MGI:Chrna7)
pubmed:18986241 bp(GO:aging) increases p(HGNC:NGFR)
pubmed:11230871 bp(GO:aging) negativeCorrelation complex(a(CHEBI:epibatidine), p(FPLX:CHRN))
pubmed:11230871 bp(GO:aging) negativeCorrelation complex(a(CHEBI:epibatidine), p(FPLX:CHRN))
pubmed:11230871 bp(GO:aging) causesNoChange r(HGNC:CHRNA3)
pubmed:4255369 bp(GO:aging) positiveCorrelation a(CONSO:"Tau fibrils")
pubmed:4255369 bp(GO:aging) positiveCorrelation a(CONSO:"Tau oligomers")
pubmed:31413141 bp(GO:aging) positiveCorrelation p(HGNC:TREM2, frag("?"))
pubmed:23454242 bp(GO:aging) increases p(HGNC:PPP2R2C)
pubmed:23454242 bp(GO:aging) decreases p(HGNC:PPP2R2B)
pubmed:28083634 bp(GO:aging) increases p(MGI:Otub1)
pubmed:27491084 bp(GO:aging) decreases p(HGNCGENEFAMILY:"DNAJ (HSP40) heat shock proteins")
pubmed:27491084 bp(GO:aging) decreases p(FPLX:HSPA)
pubmed:27491084 bp(GO:aging) increases p(FPLX:HSPB)
pubmed:30562574 bp(GO:aging) negativeCorrelation p(HGNC:LAMP2)
pubmed:30562574 bp(GO:aging) decreases bp(GO:"chaperone-mediated autophagy")
pubmed:30562574 bp(GO:aging) association bp(GO:"chaperone-mediated autophagy")
pubmed:14556719 bp(GO:aging) negativeCorrelation act(complex(GO:"proteasome complex"))
pubmed:22908190 bp(GO:aging) negativeCorrelation act(complex(GO:"proteasome complex"))
pubmed:22908190 bp(GO:aging) negativeCorrelation act(complex(GO:"proteasome complex"))
pubmed:14556719 bp(GO:aging) negativeCorrelation bp(GO:"proteasome-mediated ubiquitin-dependent protein catabolic process")
pubmed:14556719 bp(GO:aging) increases p(HGNC:PRNP)
pubmed:23746257 bp(GO:aging) decreases bp(CONSO:Proteostasis)
pubmed:23746257 bp(GO:aging) decreases bp(CONSO:Proteostasis)
pubmed:24563850 bp(GO:aging) positiveCorrelation bp(CONSO:"non-enzymatic protein modification")
pubmed:24563850 bp(GO:aging) association bp(GO:"protein oxidation")
pubmed:30116051 bp(GO:aging) negativeCorrelation act(p(HGNC:SIRT1))
pubmed:30116051 bp(GO:aging) decreases a(CHEBI:"NAD(+)")
pubmed:29024336 bp(GO:aging) increases path(MESH:"Proteostasis Deficiencies")
pubmed:29024336 bp(GO:aging) increases path(MESH:"Proteostasis Deficiencies")
pubmed:21882945 bp(GO:aging) positiveCorrelation p(HGNC:FKBP5)
pubmed:29191965 bp(GO:aging) decreases bp(GO:locomotion)
pubmed:28877763 bp(GO:aging) increases p(MGI:Syk, pmod(go:0006468 ! "protein phosphorylation"))
pubmed:28877763 bp(GO:aging) increases p(MGI:Syk, pmod(go:0006468 ! "protein phosphorylation"))
pubmed:28877763 bp(GO:aging) increases a(CONSO:"Tau aggregates")
pubmed:26631930 bp(GO:aging) positiveCorrelation a(CONSO:"Tau aggregates")
pubmed:28877763 bp(GO:aging) increases p(MGI:Mapt, pmod(CONSO:hyperphosphorylation))
pubmed:29626319 bp(GO:aging) negativeCorrelation p(HGNC:IDE)
pubmed:25681682 bp(GO:aging) negativeCorrelation p(HGNC:AGER)
pubmed:19118186 bp(GO:aging) decreases bp(GO:memory)
pubmed:28877763 bp(GO:aging) increases a(CONSO:"dystrophic neurite")
pubmed:29421605 bp(GO:aging) positiveCorrelation p(RGD:Ptpn1)
pubmed:29421605 bp(GO:aging) negativeCorrelation p(RGD:Irs1, pmod(go:0006468 ! "protein phosphorylation"))
pubmed:29421605 bp(GO:aging) negativeCorrelation p(RGD:Akt1, pmod(go:0006468 ! "protein phosphorylation"))
pubmed:29421605 bp(GO:aging) negativeCorrelation p(RGD:Gsk3b, pmod(go:0006468 ! "protein phosphorylation"))
pubmed:29421605 bp(GO:aging) negativeCorrelation p(RGD:Mtor, pmod(go:0006468 ! "protein phosphorylation"))
pubmed:29421605 bp(GO:aging) negativeCorrelation p(RGD:Ntrk2, pmod(go:0006468 ! "protein phosphorylation"))
pubmed:29421605 bp(GO:aging) positiveCorrelation p(RGD:Mapt, pmod(go:0006468 ! "protein phosphorylation"))
pubmed:24561250 bp(GO:aging) increases act(complex(GO:"NLRP1 inflammasome complex"))
pubmed:24561250 bp(GO:aging) increases p(HGNC:IL1B)
pubmed:24561250 bp(GO:aging) increases p(HGNC:IL18)
pubmed:30046111 bp(GO:"cerebrospinal fluid circulation") decreases a(CHEBI:amyloid-beta)
pubmed:30046111 act(a(HP:"interstitial fluid")) decreases a(CHEBI:amyloid-beta)
pubmed:30046111 a(MESH:"Lymphatic Vessels") regulates bp(MESH:Homeostasis)
pubmed:30046111 a(MESH:"Lymphatic Vessels") increases tloc(a(CHEBI:macromolecule), fromLoc(MESH:"Cerebrospinal Fluid"), toLoc(MESH:"Lymph Nodes"))
pubmed:30046111 act(a(MESH:"Lymphatic Vessels")) association tloc(a(CHEBI:macromolecule), fromLoc(GO:"extracellular space"), toLoc(MESH:"Intracellular Space"))
pubmed:30046111 act(a(MESH:"Lymphatic Vessels")) increases tloc(a(CHEBI:macromolecule), fromLoc(MESH:"Parenchymal Tissue"), toLoc(MESH:"Lymph Nodes"))
pubmed:30046111 act(a(MESH:"Lymphatic Vessels")) increases tloc(a(CHEBI:macromolecule), fromLoc(HP:"interstitial fluid"), toLoc(MESH:"Lymph Nodes"))
pubmed:30046111 act(a(MESH:"Lymphatic Vessels")) increases tloc(a(CHEBI:macromolecule), fromLoc(MESH:"Cerebrospinal Fluid"), toLoc(MESH:"Parenchymal Tissue"))
pubmed:30046111 act(a(MESH:"Lymphatic Vessels")) increases bp(MESH:"Cerebrovascular Circulation")
pubmed:30046111 act(a(MESH:"Lymphatic Vessels")) increases bp(MESH:"Cerebrovascular Circulation")
pubmed:30046111 act(a(MESH:"Lymphatic Vessels")) association bp(MESH:"Cerebrovascular Circulation")
pubmed:30046111 act(a(MESH:"Lymphatic Vessels")) positiveCorrelation bp(MESH:"Cerebrovascular Circulation")
pubmed:30046111 act(a(MESH:"Lymphatic Vessels")) increases bp(GO:"cerebrospinal fluid secretion")
pubmed:30046111 act(a(MESH:"Lymphatic Vessels")) increases tloc(a(CHEBI:"gadolinium atom"), fromLoc(GO:"extracellular space"), toLoc(MESH:"Cerebrospinal Fluid"))
pubmed:30046111 act(a(MESH:"Lymphatic Vessels")) increases bp(GO:"fear response")
pubmed:30046111 act(a(MESH:"Lymphatic Vessels")) increases path(MESH:"Spatial Learning")
pubmed:30046111 act(a(MESH:"Lymphatic Vessels")) increases path(MESH:"Spatial Learning")
pubmed:30046111 act(a(MESH:"Lymphatic Vessels")) increases bp(GO:memory)
pubmed:30046111 act(a(MESH:"Lymphatic Vessels")) increases bp(GO:memory)
pubmed:30046111 act(a(MESH:"Lymphatic Vessels")) association bp(GO:"gene expression")
pubmed:30046111 act(a(MESH:"Lymphatic Vessels")) association path(MESH:"Huntington Disease")
pubmed:30046111 act(a(MESH:"Lymphatic Vessels")) association path(MESH:"Parkinson Disease")
pubmed:30046111 act(a(MESH:"Lymphatic Vessels")) association path(MESH:"Alzheimer Disease")
pubmed:30046111 act(a(MESH:"Lymphatic Vessels")) association bp(GO:"excitatory chemical synaptic transmission")
pubmed:30046111 act(a(MESH:"Lymphatic Vessels")) increases bp(GO:learning)
pubmed:30046111 act(a(MESH:"Lymphatic Vessels")) increases bp(GO:cognition)
pubmed:30046111 act(a(MESH:"Lymphatic Vessels")) association bp(GO:"neuronal signal transduction")
pubmed:30046111 act(a(MESH:"Lymphatic Vessels")) regulates a(CHEBI:metabolite)
pubmed:30046111 act(a(MESH:"Lymphatic Vessels")) regulates bp(MESH:Glycolysis)
pubmed:30046111 act(a(MESH:"Lymphatic Vessels")) regulates bp(GO:"response to oxidative stress")
pubmed:30046111 act(a(MESH:"Lymphatic Vessels")) regulates bp(GO:"cellular respiration")
pubmed:30046111 act(a(MESH:"Lymphatic Vessels")) negativeCorrelation bp(GO:aging)
pubmed:30046111 act(a(MESH:"Lymphatic Vessels")) increases act(p(MGI:Vegfc))
pubmed:30046111 act(a(MESH:"Lymphatic Vessels")) decreases a(CHEBI:amyloid-beta)
pubmed:30046111 act(a(MESH:"Lymphatic Vessels")) negativeCorrelation a(CHEBI:amyloid-beta)
pubmed:30046111 act(a(MESH:"Lymphatic Vessels")) decreases a(CHEBI:amyloid-beta)
pubmed:30046111 act(a(MESH:"Lymphatic Vessels")) decreases a(CHEBI:amyloid-beta)
pubmed:30046111 a(MESH:"Lymphatic Vessels") decreases a(CHEBI:amyloid-beta)
pubmed:30046111 act(a(MESH:"Lymphatic Vessels")) decreases bp(GO:"macrophage migration")
pubmed:30046111 act(a(MESH:"Lymphatic Vessels")) decreases a(MESH:Macrophages)
pubmed:30046111 act(a(MESH:"Lymphatic Vessels")) negativeCorrelation path(MESH:Inflammation)
pubmed:30046111 act(a(MESH:"Lymphatic Vessels")) decreases a(CONSO:CONSO00018)
pubmed:30967783 bp(MESH:Homeostasis) increases a(MESH:Monocytes)
pubmed:30967783 bp(MESH:Homeostasis) increases bp(GO:"microglial cell activation")
pubmed:30046111 tloc(a(CHEBI:macromolecule), fromLoc(GO:"extracellular space"), toLoc(MESH:"Intracellular Space")) association act(a(MESH:"Lymphatic Vessels"))
pubmed:30046111 a(CHEBI:verteporfin) decreases a(MESH:"Lymphatic Vessels")
pubmed:30046111 a(CHEBI:verteporfin) decreases act(a(MESH:"Lymphatic Vessels"))
pubmed:30046111 a(CHEBI:verteporfin) decreases bp(MESH:"Cerebrovascular Circulation")
pubmed:30046111 a(CHEBI:verteporfin) decreases tloc(a(CHEBI:"gadolinium atom"), fromLoc(GO:"extracellular space"), toLoc(MESH:"Cerebrospinal Fluid"))
pubmed:30046111 bp(MESH:"Cerebrovascular Circulation") association act(a(MESH:"Lymphatic Vessels"))
pubmed:30046111 bp(MESH:"Cerebrovascular Circulation") increases act(a(MESH:"Lymphatic Vessels"))
pubmed:30046111 bp(MESH:"Cerebrovascular Circulation") positiveCorrelation act(a(MESH:"Lymphatic Vessels"))
pubmed:30046111 bp(MESH:"Cerebrovascular Circulation") increases tloc(a(CHEBI:macromolecule), fromLoc(GO:"extracellular space"), toLoc(MESH:"Intracellular Space"))
pubmed:30126037 bp(MESH:"Cerebrovascular Circulation") association p(MGI:Mapt, var("p.Pro301Leu"))
pubmed:30126037 bp(MESH:"Cerebrovascular Circulation") association path(MESH:"Alzheimer Disease")
pubmed:30126037 bp(MESH:"Cerebrovascular Circulation") association path(MESH:"Cognitive Dysfunction")
pubmed:30046111 p(MGI:Aqp4) regulates tloc(a(CHEBI:macromolecule), fromLoc(GO:"extracellular space"), toLoc(MESH:"Intracellular Space"))
pubmed:30046111 p(MGI:Aqp4) regulates tloc(a(CHEBI:macromolecule), fromLoc(MESH:"Intracellular Space"), toLoc(GO:"extracellular space"))
pubmed:30046111 p(MGI:Aqp4) decreases a(CHEBI:amyloid-beta)
pubmed:30046111 p(MGI:Aqp4) increases bp(GO:cognition)
pubmed:27889190 bp(GO:cognition) association path(DOID:"multiple sclerosis")
pubmed:27889190 bp(GO:cognition) association path(DOID:"acute disseminated encephalomyelitis")
pubmed:25031639 bp(GO:cognition) positiveCorrelation g(HGNC:HDAC6)
pubmed:25031639 bp(GO:cognition) positiveCorrelation a(CHEBI:"epothilone D")
pubmed:30270813 bp(GO:cognition) negativeCorrelation a(CHEBI:cisplatin)
pubmed:29661268 bp(GO:cognition) positiveCorrelation a(CHEBI:"lithium atom")
pubmed:22236693 bp(GO:cognition) negativeCorrelation g(HGNC:NGFR)
pubmed:21036197 bp(GO:cognition) association g(HGNC:NR3C2)
pubmed:24586483 bp(GO:cognition) negativeCorrelation g(DBSNP:rs57095329)
pubmed:26235064 bp(GO:cognition) association p(HGNC:MAPT)
pubmed:19126755 bp(GO:cognition) positiveCorrelation p(CONSO:"alpha-4 beta-2 nAChR")
pubmed:21482353 bp(GO:cognition) positiveCorrelation p(CONSO:"alpha-4 beta-2 nAChR")
pubmed:19126755 bp(GO:cognition) positiveCorrelation p(HGNC:CHRNA7)
pubmed:19126755 bp(GO:cognition) association act(p(HGNC:CHRNA7))
pubmed:27190210 bp(GO:cognition) association p(HGNC:CHRNA7)
pubmed:19721446 bp(GO:cognition) positiveCorrelation p(HGNC:CHRNA7)
pubmed:19126755 bp(GO:cognition) negativeCorrelation path(MESH:"Alzheimer Disease")
pubmed:24511233 bp(GO:cognition) association path(MESH:"Alzheimer Disease")
pubmed:11230871 bp(GO:cognition) negativeCorrelation path(MESH:"Alzheimer Disease")
pubmed:24511233 bp(GO:cognition) association path(MESH:Schizophrenia)
pubmed:19721446 bp(GO:cognition) association path(MESH:Schizophrenia)
pubmed:24511233 bp(GO:cognition) association a(MESH:Hippocampus)
pubmed:24511233 bp(GO:cognition) association a(MESH:"Cerebral Cortex")
pubmed:24511233 bp(GO:cognition) association bp(GO:"synaptic transmission, cholinergic")
pubmed:26813123 bp(GO:cognition) association bp(GO:"synaptic transmission, cholinergic")
pubmed:21482353 bp(GO:cognition) association bp(GO:"synaptic transmission, cholinergic")
pubmed:24511233 bp(GO:cognition) association p(HGNC:CHRM1)
pubmed:24511233 bp(GO:cognition) association p(HGNCGENEFAMILY:"Glutamate ionotropic receptor NMDA type subunits")
pubmed:24511233 bp(GO:cognition) association a(MESH:"Prefrontal Cortex")
pubmed:27190210 bp(GO:cognition) association g(HGNC:CHRNA7)
pubmed:26813123 bp(GO:cognition) association bp(GO:"synaptic transmission, glutamatergic")
pubmed:30697142 bp(GO:cognition) positiveCorrelation bp(GO:"synaptic transmission, glutamatergic")
pubmed:26813123 bp(GO:cognition) association a(CHEBI:acetylcholine)
pubmed:11230871 bp(GO:cognition) negativeCorrelation a(CHEBI:acetylcholine)
pubmed:25514383 bp(GO:cognition) association a(HP:"cholinergic neuron")
pubmed:30697142 bp(GO:cognition) positiveCorrelation a(CHEBI:"(-)-cotinine")
pubmed:30697142 bp(GO:cognition) negativeCorrelation p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation"))
pubmed:28445721 bp(GO:cognition) association p(FPLX:CHRN)
pubmed:28445721 bp(GO:cognition) association p(FPLX:CHRN)
pubmed:28445721 bp(GO:cognition) association p(FPLX:CHRN)
pubmed:11230871 bp(GO:cognition) association p(FPLX:CHRN)
pubmed:21482353 bp(GO:cognition) positiveCorrelation p(HGNC:CHRNA5, var("?"))
pubmed:21482353 bp(GO:cognition) positiveCorrelation p(HGNC:CHRNA3, var("?"))
pubmed:21482353 bp(GO:cognition) positiveCorrelation p(HGNC:CHRNB4, var("?"))
pubmed:11230871 bp(GO:cognition) association complex(a(CHEBI:nicotine), p(FPLX:CHRN))
pubmed:11230871 bp(GO:cognition) association a(CHEBI:neurotransmitter)
pubmed:23516100 bp(GO:cognition) negativeCorrelation p(HGNC:MAPT, frag("1_421"))
pubmed:30108137 bp(GO:cognition) negativeCorrelation r(HGNC:TFEB)
pubmed:22908190 bp(GO:cognition) positiveCorrelation act(a(GO:synapse))
pubmed:24027553 bp(GO:cognition) negativeCorrelation p(CONSO:"Tau C3")
pubmed:21882945 bp(GO:cognition) negativeCorrelation path(MESH:Tauopathies)
pubmed:21882945 bp(GO:cognition) positiveCorrelation a(PUBCHEM:134222899)
pubmed:21882945 bp(GO:cognition) positiveCorrelation a(CHEBI:"NMDA receptor antagonist")
pubmed:30985105 bp(GO:cognition) association a(CHEBI:amyloid-beta)
pubmed:30988501 bp(GO:cognition) association bp(MESH:"Immunity, Cellular")
pubmed:30988501 bp(GO:cognition) association bp(MESH:"Immunity, Cellular")
pubmed:30988501 bp(GO:cognition) association path(MESH:"Illness Behavior")
pubmed:30988501 bp(GO:cognition) association path(MESH:Inflammation)
pubmed:24808823 path(MESH:"Spatial Learning") negativeCorrelation p(MGI:Ttbk1)
pubmed:24808823 path(MESH:"Spatial Learning") negativeCorrelation p(MGI:Cdk5)
pubmed:24808823 path(MESH:"Spatial Learning") positiveCorrelation tloc(p(MGI:Grin2b), fromLoc(go:0005622 ! intracellular), toLoc(go:0009986 ! "cell surface"))
pubmed:24107444 bp(GO:memory) positiveCorrelation p(MGI:Ncstn)
pubmed:29179999 bp(GO:memory) association a(CHEBI:"amyloid-beta polypeptide 42")
pubmed:29661268 bp(GO:memory) negativeCorrelation p(HGNC:MAPT, var("p.Lys?Gln"))
pubmed:29661268 bp(GO:memory) negativeCorrelation p(HGNC:MAPT, pmod(go:0006473 ! "protein acetylation", Lys, 274))
pubmed:29661268 bp(GO:memory) negativeCorrelation p(HGNC:MAPT, pmod(go:0006473 ! "protein acetylation", Lys, 281))
pubmed:21673407 bp(GO:memory) association p(HGNC:HTR4)
pubmed:30515821 bp(GO:memory) positiveCorrelation p(HGNC:DNM1)
pubmed:19293145 bp(GO:memory) association composite(p(HGNC:MAPK1), p(HGNC:MAPK3))
pubmed:24511233 bp(GO:memory) association a(MESH:Hippocampus)
pubmed:24511233 bp(GO:memory) association a(MESH:Hippocampus)
pubmed:19721446 bp(GO:memory) association a(MESH:Hippocampus)
pubmed:24511233 bp(GO:memory) association a(MESH:"Cerebral Cortex")
pubmed:24511233 bp(GO:memory) association a(MESH:"Cerebral Cortex")
pubmed:24511233 bp(GO:memory) association bp(GO:"long-term synaptic potentiation")
pubmed:24511233 bp(GO:memory) association a(MESH:"Prefrontal Cortex")
pubmed:17009926 bp(GO:memory) association p(FPLX:CHRN)
pubmed:11230871 bp(GO:memory) association p(FPLX:CHRN)
pubmed:22530628 bp(GO:memory) association act(p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits"))
pubmed:26813123 bp(GO:memory) association bp(GO:"synaptic transmission, cholinergic")
pubmed:21482353 bp(GO:memory) association bp(GO:"synaptic transmission, cholinergic")
pubmed:26813123 bp(GO:memory) positiveCorrelation a(CHEBI:acetylcholine)
pubmed:26813123 bp(GO:memory) association a(CHEBI:acetylcholine)
pubmed:26813123 bp(GO:memory) positiveCorrelation a(MESH:"Cholinergic Neurons")
pubmed:26813123 bp(GO:memory) negativeCorrelation path(CONSO:Neurodegeneration)
pubmed:26813123 bp(GO:memory) association bp(MESH:"Synaptic Transmission")
pubmed:26813123 bp(GO:memory) association p(HGNC:SYP)
pubmed:24590577 bp(GO:memory) association p(HGNCGENEFAMILY:"Cholinergic receptors muscarinic")
pubmed:24590577 bp(GO:memory) association p(HGNC:CHRM1)
pubmed:19721446 bp(GO:memory) association p(HGNC:CHRNA7)
pubmed:19721446 bp(GO:memory) association a(MESH:"Entorhinal Cortex")
pubmed:23516100 bp(GO:memory) negativeCorrelation p(HGNC:CTSB)
pubmed:30106381 bp(GO:memory) association p(HGNC:ADNP)
pubmed:30012004 bp(GO:memory) negativeCorrelation path(MESH:"Huntington Disease")
pubmed:22908190 bp(GO:memory) association bp(GO:"proteasome-mediated ubiquitin-dependent protein catabolic process")
pubmed:19118186 bp(GO:memory) negativeCorrelation p(MGI:Mapt)
pubmed:28775333 bp(GO:memory) positiveCorrelation a(CHEBI:"(-)-epigallocatechin 3-gallate")
pubmed:28775333 bp(GO:memory) negativeCorrelation p(MGI:Dyrk1a)
pubmed:24355211 bp(GO:memory) negativeCorrelation p(HGNC:GSK3B)
pubmed:27041503 bp(GO:memory) association p(HGNC:WWC1)
pubmed:28771976 bp(GO:memory) association a(CONSO:RGFP966)
pubmed:21843595 bp(GO:memory) negativeCorrelation p(MGI:Sumo3)
pubmed:30046111 bp(GO:"gene expression") association act(a(MESH:"Lymphatic Vessels"))
pubmed:30046111 path(MESH:"Huntington Disease") association act(a(MESH:"Lymphatic Vessels"))
pubmed:30663117 path(MESH:"Huntington Disease") association path(MESH:Chorea)
pubmed:29687724 path(MESH:"Huntington Disease") association path(MESH:Chorea)
pubmed:30027901 path(MESH:"Huntington Disease") increases path(MESH:Chorea)
pubmed:30027901 path(MESH:"Huntington Disease") increases path(MESH:Chorea)
pubmed:30027901 path(MESH:"Huntington Disease") increases path(MESH:Chorea)
pubmed:30027901 path(MESH:"Huntington Disease") increases path(MESH:Chorea)
pubmed:30663117 path(MESH:"Huntington Disease") association path(MESH:Dementia)
pubmed:30012004 path(MESH:"Huntington Disease") positiveCorrelation path(MESH:Dementia)
pubmed:30027901 path(MESH:"Huntington Disease") increases path(MESH:Dementia)
pubmed:30663117 path(MESH:"Huntington Disease") association path(MESH:"Deglutition Disorders")
pubmed:30663117 path(MESH:"Huntington Disease") association path(MESH:Aphasia)
pubmed:30663117 path(MESH:"Huntington Disease") association path(MESH:Seizures)
pubmed:30663117 path(MESH:"Huntington Disease") association g(HGNC:MIR196A1)
pubmed:30663117 path(MESH:"Huntington Disease") increases g(HGNC:MIR196A1)
pubmed:30663117 path(MESH:"Huntington Disease") association g(HGNC:MIR206)
pubmed:30663117 path(MESH:"Huntington Disease") association g(HGNC:MIR301B)
pubmed:30663117 path(MESH:"Huntington Disease") association g(HGNC:MIR92B)
pubmed:30663117 path(MESH:"Huntington Disease") association g(HGNC:MIR378B)
pubmed:30663117 path(MESH:"Huntington Disease") association g(HGNC:MIR208B)
pubmed:30663117 path(MESH:"Huntington Disease") association g(HGNC:MIR449A)
pubmed:30663117 path(MESH:"Huntington Disease") decreases g(NCBIGENE:406915)
pubmed:30663117 path(MESH:"Huntington Disease") increases g(MIRBASE:hsa-mir-10b)
pubmed:30663117 path(MESH:"Huntington Disease") increases g(HGNC:MIR196B)
pubmed:30663117 path(MESH:"Huntington Disease") increases g(HGNC:MIR615)
pubmed:30663117 path(MESH:"Huntington Disease") increases g(HGNC:MIR1247)
pubmed:30663117 path(MESH:"Huntington Disease") decreases g(MGI:Mir22)
pubmed:30663117 path(MESH:"Huntington Disease") decreases g(MGI:Mir29c)
pubmed:30663117 path(MESH:"Huntington Disease") decreases g(MGI:Mir128-1)
pubmed:30663117 path(MESH:"Huntington Disease") decreases g(MGI:Mir132)
pubmed:30663117 path(MESH:"Huntington Disease") decreases g(MGI:Mir138-1)
pubmed:30663117 path(MESH:"Huntington Disease") decreases g(MGI:Mir218-1)
pubmed:30663117 path(MESH:"Huntington Disease") decreases g(MGI:Mir222)
pubmed:30663117 path(MESH:"Huntington Disease") decreases g(NCBIGENE:723931)
pubmed:30663117 path(MESH:"Huntington Disease") decreases g(NCBIGENE:732489)
pubmed:26813123 path(MESH:"Huntington Disease") negativeCorrelation act(p(HGNC:CHAT))
pubmed:30027901 path(MESH:"Huntington Disease") decreases act(p(HGNC:CHAT))
pubmed:30362565 path(MESH:"Huntington Disease") association path(MESH:"Neurodegenerative Diseases")
pubmed:29687724 path(MESH:"Huntington Disease") association path(MESH:"Neurodegenerative Diseases")
pubmed:30027901 path(MESH:"Huntington Disease") isA path(MESH:"Neurodegenerative Diseases")
pubmed:30362565 path(MESH:"Huntington Disease") decreases act(p(HGNC:HTT))
pubmed:30362565 path(MESH:"Huntington Disease") decreases path(MESH:"Organelle Biogenesis")
pubmed:30362565 path(MESH:"Huntington Disease") association path(MESH:Autophagy)
pubmed:30362565 path(MESH:"Huntington Disease") decreases path(MESH:"Mitochondrial Dynamics")
pubmed:30362565 path(MESH:"Huntington Disease") decreases path(MESH:"Protein Transport")
pubmed:30362565 path(MESH:"Huntington Disease") decreases a(CHEBI:ATP)
pubmed:30012004 path(MESH:"Huntington Disease") positiveCorrelation bp(GO:"neuron death")
pubmed:30012004 path(MESH:"Huntington Disease") positiveCorrelation bp(GO:"neuron death")
pubmed:27013968 path(MESH:"Huntington Disease") increases bp(GO:"neuron death")
pubmed:30027901 path(MESH:"Huntington Disease") increases bp(GO:"neuron death")
pubmed:30012004 path(MESH:"Huntington Disease") positiveCorrelation path(MESH:Atrophy)
pubmed:30012004 path(MESH:"Huntington Disease") positiveCorrelation path(CONSO:Excitotoxicity)
pubmed:30027901 path(MESH:"Huntington Disease") association path(CONSO:Excitotoxicity)
pubmed:30012004 path(MESH:"Huntington Disease") positiveCorrelation path(MESH:"Oxidative Stress")
pubmed:30012004 path(MESH:"Huntington Disease") negativeCorrelation bp(MESH:"Energy Metabolism")
pubmed:30012004 path(MESH:"Huntington Disease") positiveCorrelation path(CONSO:"mitochondrial dysfunction")
pubmed:30012004 path(MESH:"Huntington Disease") positiveCorrelation path(MESH:Inflammation)
pubmed:30012004 path(MESH:"Huntington Disease") positiveCorrelation bp(GO:"apoptotic process")
pubmed:30012004 path(MESH:"Huntington Disease") positiveCorrelation bp(GO:autophagy)
pubmed:30012004 path(MESH:"Huntington Disease") negativeCorrelation bp(GO:"dopamine metabolic process")
pubmed:30012004 path(MESH:"Huntington Disease") negativeCorrelation bp(GO:"D-glutamate metabolic process")
pubmed:30012004 path(MESH:"Huntington Disease") negativeCorrelation bp(GO:"cannabinoid biosynthetic process")
pubmed:30012004 path(MESH:"Huntington Disease") negativeCorrelation bp(GO:"adenosine catabolic process")
pubmed:30012004 path(MESH:"Huntington Disease") negativeCorrelation a(MESH:"Gray Matter")
pubmed:30012004 path(MESH:"Huntington Disease") negativeCorrelation a(MESH:"White Matter")
pubmed:30012004 path(MESH:"Huntington Disease") negativeCorrelation bp(GO:"motor behavior")
pubmed:29687724 path(MESH:"Huntington Disease") decreases bp(GO:"motor behavior")
pubmed:30012004 path(MESH:"Huntington Disease") negativeCorrelation bp(GO:memory)
pubmed:30012004 path(MESH:"Huntington Disease") negativeCorrelation bp(GO:"psychomotor behavior")
pubmed:30012004 path(MESH:"Huntington Disease") negativeCorrelation bp(GO:"sensory perception")
pubmed:30012004 path(MESH:"Huntington Disease") negativeCorrelation bp(GO:"visual learning")
pubmed:29687724 path(MESH:"Huntington Disease") association path(MESH:Cognition)
pubmed:29687724 path(MESH:"Huntington Disease") decreases bp(GO:behavior)
pubmed:29687724 path(MESH:"Huntington Disease") association path(MESH:Dystonia)
pubmed:29687724 path(MESH:"Huntington Disease") association path(MESH:"Neural Pathways")
pubmed:29687724 path(MESH:"Huntington Disease") association a(CHEBI:dopamine)
pubmed:30027901 path(MESH:"Huntington Disease") increases a(CHEBI:dopamine)
pubmed:29687724 path(MESH:"Huntington Disease") association path(MESH:Depression)
pubmed:30027901 path(MESH:"Huntington Disease") increases path(MESH:Depression)
pubmed:30027901 path(MESH:"Huntington Disease") increases path(MESH:Depression)
pubmed:30027901 path(MESH:"Huntington Disease") increases path(MESH:Depression)
pubmed:29687724 path(MESH:"Huntington Disease") association path(MESH:"Motor Disorders")
pubmed:29687724 path(MESH:"Huntington Disease") association path(MESH:"Schizophrenia, Disorganized")
pubmed:29687724 path(MESH:"Huntington Disease") association path(MESH:"Cognitive Dysfunction")
pubmed:29687724 path(MESH:"Huntington Disease") association a(CHEBI:amantadine)
pubmed:29687724 path(MESH:"Huntington Disease") association a(PUBCHEM:9795739)
pubmed:27013968 path(MESH:"Huntington Disease") increases path(HP:"Autosomal dominant inheritance")
pubmed:30027901 path(MESH:"Huntington Disease") increases path(HP:"Autosomal dominant inheritance")
pubmed:30027901 path(MESH:"Huntington Disease") increases path(HP:"Autosomal dominant inheritance")
pubmed:27013968 path(MESH:"Huntington Disease") increases path(MESH:Hyperkinesis)
pubmed:27013968 path(MESH:"Huntington Disease") increases path(HP:"Behavioral abnormality")
pubmed:30027901 path(MESH:"Huntington Disease") increases path(HP:"Behavioral abnormality")
pubmed:30027901 path(MESH:"Huntington Disease") increases path(HP:"Behavioral abnormality")
pubmed:27013968 path(MESH:"Huntington Disease") association p(HGNC:HTT, pmod(HBP:"CAG repeats"))
pubmed:27013968 path(MESH:"Huntington Disease") decreases p(HGNC:BDNF)
pubmed:27013968 path(MESH:"Huntington Disease") causesNoChange p(HGNC:BDNF)
pubmed:27013968 path(MESH:"Huntington Disease") decreases act(p(HGNC:BDNF))
pubmed:27013968 path(MESH:"Huntington Disease") causesNoChange p(HGNC:BDNF)
pubmed:30027901 path(MESH:"Huntington Disease") decreases p(HGNC:BDNF)
pubmed:27013968 path(MESH:"Huntington Disease") decreases p(HGNC:NTRK2)
pubmed:27013968 path(MESH:"Huntington Disease") decreases act(p(HGNC:NTRK2))
pubmed:27013968 path(MESH:"Huntington Disease") causesNoChange p(HGNC:NTRK2)
pubmed:27013968 path(MESH:"Huntington Disease") causesNoChange p(HGNC:NTRK2)
pubmed:27013968 path(MESH:"Huntington Disease") decreases act(p(HGNC:NTRK2))
pubmed:27013968 path(MESH:"Huntington Disease") decreases p(HGNC:NTRK2, pmod(go:0006468 ! "protein phosphorylation"))
pubmed:27013968 path(MESH:"Huntington Disease") decreases p(HGNC:NTRK2, pmod(go:0006468 ! "protein phosphorylation"))
pubmed:27013968 path(MESH:"Huntington Disease") decreases bp(GO:"ERK1 and ERK2 cascade")
pubmed:27013968 path(MESH:"Huntington Disease") decreases bp(GO:"ERK1 and ERK2 cascade")
pubmed:27013968 path(MESH:"Huntington Disease") causesNoChange a(MESH:Neurons)
pubmed:27013968 path(MESH:"Huntington Disease") decreases p(PFAM:DARPP-32)
pubmed:27013968 path(MESH:"Huntington Disease") causesNoChange bp(GO:"maintenance of cell number")
pubmed:27013968 path(MESH:"Huntington Disease") causesNoChange bp(GO:"maintenance of cell number")
pubmed:27013968 path(MESH:"Huntington Disease") causesNoChange p(HGNC:MAPK3)
pubmed:27013968 path(MESH:"Huntington Disease") causesNoChange p(HGNC:MAPK1)
pubmed:27013968 path(MESH:"Huntington Disease") causesNoChange p(HGNC:MAPK3, pmod(go:0006468 ! "protein phosphorylation"))
pubmed:27013968 path(MESH:"Huntington Disease") causesNoChange p(HGNC:MAPK1, pmod(go:0006468 ! "protein phosphorylation"))
pubmed:30027901 path(MESH:"Huntington Disease") decreases path(MESH:"Motor Activity")
pubmed:30027901 path(MESH:"Huntington Disease") decreases path(MESH:"Motor Activity")
pubmed:30027901 path(MESH:"Huntington Disease") decreases path(MESH:"Motor Activity")
pubmed:30027901 path(MESH:"Huntington Disease") decreases bp(GO:cognition)
pubmed:30027901 path(MESH:"Huntington Disease") decreases bp(GO:cognition)
pubmed:30027901 path(MESH:"Huntington Disease") increases path(HP:Dyskinesia)
pubmed:30027901 path(MESH:"Huntington Disease") increases path(DOID:dystonia)
pubmed:30027901 path(MESH:"Huntington Disease") increases path(DOID:dystonia)
pubmed:30027901 path(MESH:"Huntington Disease") increases path(DOID:dystonia)
pubmed:30027901 path(MESH:"Huntington Disease") increases path(MESH:Anxiety)
pubmed:30027901 path(MESH:"Huntington Disease") increases path(DOID:"sleep disorder")
pubmed:30027901 path(MESH:"Huntington Disease") increases path(HP:"Cognitive impairment")
pubmed:30027901 path(MESH:"Huntington Disease") increases path(HP:"Cognitive impairment")
pubmed:30027901 path(MESH:"Huntington Disease") increases path(HP:"Cognitive impairment")
pubmed:30027901 path(MESH:"Huntington Disease") increases path(MESH:Neuropathology)
pubmed:30027901 path(MESH:"Huntington Disease") increases path(HP:"Atrophy/Degeneration involving the caudate nucleus")
pubmed:30027901 path(MESH:"Huntington Disease") increases path(HP:"Atrophy/Degeneration involving the caudate nucleus")
pubmed:30027901 path(MESH:"Huntington Disease") increases path(HP:"Abnormal putamen morphology")
pubmed:30027901 path(MESH:"Huntington Disease") increases path(HP:"Abnormal putamen morphology")
pubmed:30027901 path(MESH:"Huntington Disease") increases path(HP:"Abnormal putamen morphology")
pubmed:30027901 path(MESH:"Huntington Disease") increases path(MESH:"Suicidal Ideation")
pubmed:30027901 path(MESH:"Huntington Disease") increases path(MESH:"Suicidal Ideation")
pubmed:30027901 path(MESH:"Huntington Disease") association path(MESH:"Westphal disease")
pubmed:30027901 path(MESH:"Huntington Disease") increases path(HP:Bradykinesia)
pubmed:30027901 path(MESH:"Huntington Disease") increases path(HP:"Oculomotor apraxia")
pubmed:30027901 path(MESH:"Huntington Disease") increases path(MESH:"Cognitive Dissonance")
pubmed:30027901 path(MESH:"Huntington Disease") decreases bp(GO:"learning or memory")
pubmed:30027901 path(MESH:"Huntington Disease") increases path(MESH:Apathy)
pubmed:30027901 path(MESH:"Huntington Disease") increases path(HP:Irritability)
pubmed:30027901 path(MESH:"Huntington Disease") increases path(HP:"Abnormality of the cerebral subcortex")
pubmed:30027901 path(MESH:"Huntington Disease") increases path(HP:"Sleep disturbance")
pubmed:30027901 path(MESH:"Huntington Disease") decreases a(MESH:Neostriatum)
pubmed:30027901 path(MESH:"Huntington Disease") increases path(HP:"Cerebral white matter atrophy")
pubmed:30027901 path(MESH:"Huntington Disease") increases path(HP:"Neuronal loss in the cerebral cortex")
pubmed:30027901 path(MESH:"Huntington Disease") increases path(HP:"Cerebellar atrophy")
pubmed:30027901 path(MESH:"Huntington Disease") decreases a(CHEBI:"gamma-aminobutyric acid")
pubmed:30027901 path(MESH:"Huntington Disease") decreases a(CHEBI:"gamma-aminobutyric acid")
pubmed:30027901 path(MESH:"Huntington Disease") decreases p(HGNC:GAD1)
pubmed:30027901 path(MESH:"Huntington Disease") decreases p(HGNC:GAD1)
pubmed:30027901 path(MESH:"Huntington Disease") decreases complex(GO:"GABA receptor complex")
pubmed:30027901 path(MESH:"Huntington Disease") causesNoChange complex(GO:"GABA receptor complex")
pubmed:30027901 path(MESH:"Huntington Disease") causesNoChange p(HGNC:TH)
pubmed:30027901 path(MESH:"Huntington Disease") decreases r(HGNC:SLC18A2)
pubmed:30027901 path(MESH:"Huntington Disease") decreases r(HGNCGENEFAMILY:"Cholinergic receptors muscarinic")
pubmed:30027901 path(MESH:"Huntington Disease") decreases p(HGNC:SLC18A3)
pubmed:30027901 path(MESH:"Huntington Disease") increases a(CHEBI:serotonin)
pubmed:30027901 path(MESH:"Huntington Disease") increases a(MESH:"Hydroxyindoleacetic Acid")
pubmed:30027901 path(MESH:"Huntington Disease") decreases p(HGNC:CTH)
pubmed:30027901 path(MESH:"Huntington Disease") decreases p(MGI:Cth)
pubmed:30027901 path(MESH:"Huntington Disease") increases a(GO:autophagosome)
pubmed:30027901 path(MESH:"Huntington Disease") increases path(MESH:"Protein Aggregation, Pathological")
pubmed:30027901 path(MESH:"Huntington Disease") increases r(HGNC:MAP1LC3A)
pubmed:30027901 path(MESH:"Huntington Disease") increases r(HGNC:ULK2)
pubmed:30027901 path(MESH:"Huntington Disease") increases r(HGNC:LAMP2)
pubmed:30027901 path(MESH:"Huntington Disease") decreases r(HGNC:PINK1)
pubmed:30027901 path(MESH:"Huntington Disease") decreases r(HGNC:WDFY3)
pubmed:30027901 path(MESH:"Huntington Disease") decreases r(HGNC:FKBP1A)
pubmed:30027901 path(MESH:"Huntington Disease") increases bp(GO:"mitochondrial fragmentation involved in apoptotic process")
pubmed:30027901 path(MESH:"Huntington Disease") decreases composite(a(MESH:Autophagosomes), a(MESH:Mitochondria))
pubmed:30027901 path(MESH:"Huntington Disease") decreases bp(GO:"mRNA transcription")
pubmed:30027901 path(MESH:"Huntington Disease") increases bp(GO:"cytokine production involved in inflammatory response")
pubmed:30027901 path(MESH:"Huntington Disease") increases path(HP:"Increased inflammatory response")
pubmed:30027901 path(MESH:"Huntington Disease") increases bp(GO:"neuroinflammatory response")
pubmed:30027901 path(MESH:"Huntington Disease") increases p(OMIT:0006999)
pubmed:30027901 path(MESH:"Huntington Disease") association p(HGNCGENEFAMILY:"NF-kappa B complex subunits")
pubmed:30027901 path(MESH:"Huntington Disease") association bp(GO:"oxidative phosphorylation")
pubmed:30027901 path(MESH:"Huntington Disease") increases path(NCIT:C19375)
pubmed:30027901 path(MESH:"Huntington Disease") increases bp(GO:"regulation of cell cycle")
pubmed:30027901 path(MESH:"Huntington Disease") increases path(MESH:"Movement Disorders")
pubmed:30027901 path(MESH:"Huntington Disease") increases path(HP:Parkinsonism)
pubmed:30027901 path(MESH:"Huntington Disease") increases path(HP:Agitation)
pubmed:30027901 path(MESH:"Huntington Disease") decreases bp(GO:"energy homeostasis")
pubmed:30027901 path(MESH:"Huntington Disease") association tloc(a(CHEBI:"D-glutamate residue"), fromLoc(GO:cytoplasm), toLoc(GO:"extracellular space"))
pubmed:25437566 path(MESH:"Huntington Disease") decreases p(HGNC:HSP90AB1)
pubmed:25437566 path(MESH:"Huntington Disease") decreases p(HGNC:HSPA8)
pubmed:25437566 path(MESH:"Huntington Disease") decreases p(HGNC:HSPA14)
pubmed:25437566 path(MESH:"Huntington Disease") decreases p(HGNC:TCP1)
pubmed:14556719 path(MESH:"Huntington Disease") positiveCorrelation complex(a(MESH:"Inclusion Bodies"), a(MESH:Ubiquitin))
pubmed:14556719 path(MESH:"Huntington Disease") positiveCorrelation complex(a(GO:"proteasome complex"), a(MESH:"Inclusion Bodies"))
pubmed:22908190 path(MESH:"Huntington Disease") positiveCorrelation p(CONSO:"UBB+1")
pubmed:25784053 path(MESH:"Huntington Disease") positiveCorrelation p(FPLX:HSPA)
pubmed:25784053 path(MESH:"Huntington Disease") negativeCorrelation p(HGNC:ATF6)
pubmed:18930136 path(MESH:"Huntington Disease") increases p(HGNC:CTSD)
pubmed:18930136 path(MESH:"Huntington Disease") positiveCorrelation a(GO:autolysosome)
pubmed:29024336 path(MESH:"Huntington Disease") increases path(MESH:"Proteostasis Deficiencies")
pubmed:29311797 path(MESH:"Huntington Disease") association p(HGNC:STUB1)
pubmed:30837838 path(MESH:"Huntington Disease") association p(HGNC:TARDBP, pmod(go:0006468 ! "protein phosphorylation"), loc(GO:"inclusion body"))
pubmed:30837838 path(MESH:"Huntington Disease") association p(HGNC:TARDBP, pmod(go:0016567 ! "protein ubiquitination"), loc(GO:"inclusion body"))
pubmed:30046111 path(MESH:"Parkinson Disease") association act(a(MESH:"Lymphatic Vessels"))
pubmed:30663117 path(MESH:"Parkinson Disease") association a(CONSO:"alpha-synuclein aggregates")
pubmed:30663117 path(MESH:"Parkinson Disease") association p(HGNC:SNCA, pmod(CONSO:misfolded))
pubmed:30663117 path(MESH:"Parkinson Disease") association g(HGNC:MIR132)
pubmed:30663117 path(MESH:"Parkinson Disease") association g(NCBIGENE:406950)
pubmed:30663117 path(MESH:"Parkinson Disease") association p(HGNC:LRRK2)
pubmed:30688256 path(MESH:"Parkinson Disease") association p(HGNC:LRRK2)
pubmed:24113872 path(MESH:"Parkinson Disease") positiveCorrelation p(HGNC:LRRK2)
pubmed:30663117 path(MESH:"Parkinson Disease") decreases g(HGNC:MIR205)
pubmed:30663117 path(MESH:"Parkinson Disease") decreases p(HGNC:PARK7)
pubmed:30562574 path(MESH:"Parkinson Disease") association p(HGNC:PARK7)
pubmed:30663117 path(MESH:"Parkinson Disease") increases g(HGNC:MIR494)
pubmed:30663117 path(MESH:"Parkinson Disease") decreases g(HGNC:MIR34B)
pubmed:30663117 path(MESH:"Parkinson Disease") decreases g(HGNC:MIR34C)
pubmed:20869593 path(MESH:"Parkinson Disease") association p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation"))
pubmed:19126755 path(MESH:"Parkinson Disease") association p(CONSO:"alpha-6 alpha-4 beta-2 beta-3 nAChR", loc(MESH:"Basal Ganglia"))
pubmed:19126755 path(MESH:"Parkinson Disease") positiveCorrelation path(MESH:Tremor)
pubmed:19126755 path(MESH:"Parkinson Disease") positiveCorrelation path(MESH:Hypokinesia)
pubmed:19126755 path(MESH:"Parkinson Disease") positiveCorrelation path(MESH:"Muscle Rigidity")
pubmed:19126755 path(MESH:"Parkinson Disease") negativeCorrelation path(MESH:"Tobacco Use Disorder")
pubmed:17009926 path(MESH:"Parkinson Disease") negativeCorrelation act(p(FPLX:CHRN))
pubmed:17009926 path(MESH:"Parkinson Disease") negativeCorrelation p(FPLX:CHRN)
pubmed:11230871 path(MESH:"Parkinson Disease") association p(FPLX:CHRN)
pubmed:26813123 path(MESH:"Parkinson Disease") negativeCorrelation a(MESH:"Cholinergic Neurons")
pubmed:24590577 path(MESH:"Parkinson Disease") association p(HGNC:CHRM4)
pubmed:24590577 path(MESH:"Parkinson Disease") decreases act(a(MESH:"Dopaminergic Neurons"))
pubmed:21722302 path(MESH:"Parkinson Disease") decreases a(MESH:"Dopaminergic Neurons")
pubmed:24762290 path(MESH:"Parkinson Disease") decreases path(MESH:Memory)
pubmed:24762290 path(MESH:"Parkinson Disease") association path(MESH:Memory)
pubmed:24762290 path(MESH:"Parkinson Disease") association complex(CONSO:"alpha-4 beta-2 nAChR")
pubmed:28901280 path(MESH:"Parkinson Disease") association p(MESH:"Receptors, Nicotinic")
pubmed:22020111 path(MESH:"Parkinson Disease") positiveCorrelation a(CONSO:"protein aggregates")
pubmed:30688256 path(MESH:"Parkinson Disease") association p(HGNC:PRKN)
pubmed:21722302 path(MESH:"Parkinson Disease") association p(HGNC:PRKN)
pubmed:14556719 path(MESH:"Parkinson Disease") positiveCorrelation p(HGNC:PRKN)
pubmed:22908190 path(MESH:"Parkinson Disease") positiveCorrelation p(HGNC:PRKN)
pubmed:27181519 path(MESH:"Parkinson Disease") association p(HGNC:PRKN)
pubmed:30688256 path(MESH:"Parkinson Disease") association p(HGNC:PINK1)
pubmed:21722302 path(MESH:"Parkinson Disease") association path(CONSO:Neurodegeneration)
pubmed:21722302 path(MESH:"Parkinson Disease") association bp(CONSO:"protein aggregation")
pubmed:21722302 path(MESH:"Parkinson Disease") association bp(GO:"parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization")
pubmed:21722302 path(MESH:"Parkinson Disease") association p(HGNC:PARK7, var("?"))
pubmed:21722302 path(MESH:"Parkinson Disease") association a(MESH:Paraquat)
pubmed:21722302 path(MESH:"Parkinson Disease") decreases bp(GO:"protein quality control for misfolded or incompletely synthesized proteins")
pubmed:21722302 path(MESH:"Parkinson Disease") decreases bp(MESH:"Unfolded Protein Response")
pubmed:21722302 path(MESH:"Parkinson Disease") increases bp(GO:"neuron death")
pubmed:14556719 path(MESH:"Parkinson Disease") positiveCorrelation bp(GO:"neuron death")
pubmed:29758300 path(MESH:"Parkinson Disease") association p(HGNC:VPS35, var("?"))
pubmed:29758300 path(MESH:"Parkinson Disease") negativeCorrelation bp(GO:macroautophagy)
pubmed:14556719 path(MESH:"Parkinson Disease") negativeCorrelation bp(GO:"synaptic transmission, dopaminergic")
pubmed:14556719 path(MESH:"Parkinson Disease") negativeCorrelation bp(GO:"proteasome-mediated ubiquitin-dependent protein catabolic process")
pubmed:14556719 path(MESH:"Parkinson Disease") association p(HGNC:UCHL1, var("?"))
pubmed:14556719 path(MESH:"Parkinson Disease") association p(HGNC:UCHL1, var("p.Ile93Met"))
pubmed:14556719 path(MESH:"Parkinson Disease") association a(MESH:"Lewy Bodies")
pubmed:14556719 path(MESH:"Parkinson Disease") association p(HGNC:SNCA, var("p.Ala30Pro"))
pubmed:14556719 path(MESH:"Parkinson Disease") association p(HGNC:SNCA, var("p.Ala53Thr"))
pubmed:22908190 path(MESH:"Parkinson Disease") positiveCorrelation p(HGNC:SNCA, pmod(go:0016567 ! "protein ubiquitination"))
pubmed:22908190 path(MESH:"Parkinson Disease") association p(HGNC:UCHL1)
pubmed:18930136 path(MESH:"Parkinson Disease") positiveCorrelation a(GO:autophagosome)
pubmed:28803412 path(MESH:"Parkinson Disease") association p(HGNC:SNCA)
pubmed:28803412 path(MESH:"Parkinson Disease") positiveCorrelation a(CONSO:CONSO00093)
pubmed:27075649 path(MESH:"Parkinson Disease") positiveCorrelation a(CONSO:CONSO00016)
pubmed:30116051 path(MESH:"Parkinson Disease") association p(HGNC:PINK1, var("?"))
pubmed:30116051 path(MESH:"Parkinson Disease") association p(HGNC:PRKN, var("?"))
pubmed:30116051 path(MESH:"Parkinson Disease") association p(HGNC:LRRK2, var("?"))
pubmed:29024336 path(MESH:"Parkinson Disease") increases path(MESH:"Proteostasis Deficiencies")
pubmed:30985105 path(MESH:"Parkinson Disease") positiveCorrelation deg(a(CONSO:"Dopaminergic cell groups"))
pubmed:30985105 path(MESH:"Parkinson Disease") association complex(p(HGNC:SNCA), p(HGNC:SNCA))
pubmed:30985105 path(MESH:"Parkinson Disease") association act(p(HGNCGENEFAMILY:Calpains))
pubmed:30985105 path(MESH:"Parkinson Disease") association act(p(HGNCGENEFAMILY:Calpains))
pubmed:29311797 path(MESH:"Parkinson Disease") association p(HGNC:STUB1)
pubmed:26751493 path(MESH:"Parkinson Disease") association g(DBSNP:rs2471738)
pubmed:26751493 path(MESH:"Parkinson Disease") association g(DBSNP:rs242557)
pubmed:26631930 path(MESH:"Parkinson Disease") increases a(CHEBI:"iron(0)")
pubmed:29980653 path(MESH:"Parkinson Disease") isA path(MESH:"Neurodegenerative Diseases")
pubmed:29980653 path(MESH:"Parkinson Disease") positiveCorrelation p(HGNC:SNCA, var("?"))
pubmed:29980653 path(MESH:"Parkinson Disease") isA path(MESH:"Lewy Body Disease")
pubmed:30837838 path(MESH:"Parkinson Disease") association p(HGNC:TARDBP, pmod(go:0006468 ! "protein phosphorylation"), loc(GO:"inclusion body"))
pubmed:30837838 path(MESH:"Parkinson Disease") association p(HGNC:TARDBP, pmod(go:0016567 ! "protein ubiquitination"), loc(GO:"inclusion body"))
pubmed:30046111 bp(GO:"excitatory chemical synaptic transmission") association act(a(MESH:"Lymphatic Vessels"))
pubmed:29661268 bp(GO:learning) negativeCorrelation p(HGNC:MAPT, var("p.Lys?Gln"))
pubmed:21673407 bp(GO:learning) association p(HGNC:HTR4)
pubmed:19293145 bp(GO:learning) association path(MESH:"Alzheimer Disease")
pubmed:24511233 bp(GO:learning) association a(MESH:Hippocampus)
pubmed:24511233 bp(GO:learning) association a(MESH:Hippocampus)
pubmed:24511233 bp(GO:learning) association a(MESH:"Cerebral Cortex")
pubmed:24511233 bp(GO:learning) association a(MESH:"Cerebral Cortex")
pubmed:24511233 bp(GO:learning) association bp(GO:"long-term synaptic potentiation")
pubmed:24511233 bp(GO:learning) association a(MESH:"Prefrontal Cortex")
pubmed:17009926 bp(GO:learning) association p(FPLX:CHRN)
pubmed:26813123 bp(GO:learning) association bp(GO:"synaptic transmission, cholinergic")
pubmed:26813123 bp(GO:learning) positiveCorrelation bp(GO:"synaptic transmission, cholinergic")
pubmed:21482353 bp(GO:learning) association bp(GO:"synaptic transmission, cholinergic")
pubmed:26813123 bp(GO:learning) association a(CHEBI:acetylcholine)
pubmed:24590577 bp(GO:learning) association p(HGNC:CHRM1)
pubmed:19721446 bp(GO:learning) association p(HGNC:CHRNA7)
pubmed:30106381 bp(GO:learning) association p(HGNC:ADNP)
pubmed:22908190 bp(GO:learning) association bp(GO:"proteasome-mediated ubiquitin-dependent protein catabolic process")
pubmed:24355211 bp(GO:learning) negativeCorrelation p(HGNC:GSK3B)
pubmed:21843595 bp(GO:learning) negativeCorrelation p(MGI:Sumo3)
pubmed:30046111 bp(GO:"neuronal signal transduction") association act(a(MESH:"Lymphatic Vessels"))
pubmed:24590577 bp(GO:"neuronal signal transduction") association p(HGNC:CHRM1)
pubmed:30515821 bp(MESH:Glycolysis) increases bp(GO:"neuron differentiation")
pubmed:30515821 bp(MESH:Glycolysis) regulates bp(GO:neurogenesis)
pubmed:30935091 bp(GO:"response to oxidative stress") association p(HGNC:HDAC6)
pubmed:22110360 bp(GO:"response to oxidative stress") increases act(p(HGNC:MAP3K5))
pubmed:23092889 bp(GO:"response to oxidative stress") increases act(complex(GO:"inflammasome complex"))
pubmed:24189435 bp(GO:"response to oxidative stress") association bp(GO:"mitochondrial electron transport, cytochrome c to oxygen")
pubmed:23533697 bp(GO:"response to oxidative stress") decreases a(NIFT:"Cerebral blood flow")
pubmed:30515821 bp(GO:"response to oxidative stress") increases act(p(HGNC:DNM1))
pubmed:11230871 bp(GO:"response to oxidative stress") negativeCorrelation p(FPLX:CHRN)
pubmed:23516100 bp(GO:"response to oxidative stress") increases tloc(p(HGNC:SNCA), fromLoc(GO:cytoplasm), toLoc(GO:nucleus))
pubmed:23516100 bp(GO:"response to oxidative stress") increases act(p(HGNCGENEFAMILY:Caspases))
pubmed:27299292 bp(GO:"response to oxidative stress") increases tloc(p(HGNC:TFEB), fromLoc(GO:cytosol), toLoc(GO:nucleus))
pubmed:14556719 bp(GO:"response to oxidative stress") increases p(HGNC:SOD1, pmod(go:0016567 ! "protein ubiquitination"), var("?"))
pubmed:14556719 bp(GO:"response to oxidative stress") increases p(HGNC:SOD1, pmod(CONSO:misfolding), var("?"))
pubmed:23746257 bp(GO:"response to oxidative stress") increases a(MESH:"Heat-Shock Proteins")
pubmed:23746257 bp(GO:"response to oxidative stress") association bp(CONSO:Proteostasis)
pubmed:18930136 bp(GO:"response to oxidative stress") increases p(HGNC:SQSTM1)
pubmed:18930136 bp(GO:"response to oxidative stress") increases r(HGNC:SQSTM1)
pubmed:24563850 bp(GO:"response to oxidative stress") decreases act(p(HGNC:KEAP1))
pubmed:24563850 bp(GO:"response to oxidative stress") increases p(HGNC:NFE2L2, loc(MESH:"Cell Nucleus"))
pubmed:24563850 bp(GO:"response to oxidative stress") increases act(p(FPLX:PRDX))
pubmed:27671637 bp(GO:"response to oxidative stress") negativeCorrelation p(CONSO:"Tau isoform F (441 aa)", var("p.Lys280del"))
pubmed:23528736 bp(GO:"response to oxidative stress") increases bp(GO:autophagy)
pubmed:22419736 bp(GO:"response to oxidative stress") increases p(HGNC:AK1)
pubmed:26751493 bp(GO:"response to oxidative stress") association a(CHEBI:"methylene blue")
pubmed:26751493 bp(GO:"response to oxidative stress") association a(CHEBI:"azure A")
pubmed:26751493 bp(GO:"response to oxidative stress") association a(CHEBI:"azure B")
pubmed:27181519 bp(GO:"response to oxidative stress") increases complex(GO:"cytoplasmic stress granule")
pubmed:29844403 bp(GO:"cellular respiration") negativeCorrelation p(HGNC:MAPT, pmod(CONSO:hyperphosphorylation))
pubmed:30126037 bp(GO:"cellular respiration") association act(a(MESH:Mitochondria))
pubmed:30046111 bp(GO:"immune response") association bp(GO:aging)
pubmed:27288790 bp(GO:"immune response") association m(MIRBASE:hsa-mir-146a)
pubmed:28843454 bp(GO:"immune response") association p(HGNCGENEFAMILY:"Histocompatibility complex")
pubmed:" 26517285" bp(GO:"immune response") association bp(GO:"microglial cell activation")
pubmed:" 26517285" bp(GO:"immune response") association g(HGNC:CR1)
pubmed:" 26517285" bp(GO:"immune response") association g(HGNC:CD33)
pubmed:" 26517285" bp(GO:"immune response") association g(HGNC:MS4A1)
pubmed:" 26517285" bp(GO:"immune response") association g(HGNC:ABCA7)
pubmed:" 26517285" bp(GO:"immune response") association g(HGNC:CLU)
pubmed:" 26517285" bp(GO:"immune response") association g(HGNC:EPHA1)
pubmed:30106381 bp(GO:"immune response") association p(HGNC:ADNP)
pubmed:30106381 bp(GO:"immune response") association a(PUBCHEM:9832404)
pubmed:23746257 bp(GO:"immune response") association p(FPLX:HSP90)
pubmed:30046111 bp(GO:"inflammatory response") association bp(GO:aging)
pubmed:31346362 bp(GO:"inflammatory response") increases bp(GO:"cell death")
pubmed:31346362 bp(GO:"inflammatory response") increases deg(a(MESH:Tissues))
pubmed:29179999 bp(GO:"inflammatory response") association act(p(FPLX:NFkappaB))
pubmed:27794524 bp(GO:"inflammatory response") negativeCorrelation bp(GO:"brain development")
pubmed:27794524 bp(GO:"inflammatory response") positiveCorrelation bp(GO:"central nervous system development")
pubmed:27794524 bp(GO:"inflammatory response") increases path(MESH:"Disease Resistance")
pubmed:27794524 bp(GO:"inflammatory response") positiveCorrelation path(MESH:"Neurodegenerative Diseases")
pubmed:27794524 bp(GO:"inflammatory response") positiveCorrelation path(MESH:Atrophy)
pubmed:27794524 bp(GO:"inflammatory response") positiveCorrelation path(MESH:"Demyelinating Diseases")
pubmed:27794524 bp(GO:"inflammatory response") increases path(MESH:Pathology)
pubmed:23533697 bp(GO:"inflammatory response") association p(HGNC:TREM2)
pubmed:27522251 bp(GO:"inflammatory response") causesNoChange path(MESH:"Memory Disorders")
pubmed:21958873 bp(GO:"inflammatory response") negativeCorrelation a(CHEBI:Anatabine)
pubmed:23178521 bp(GO:"inflammatory response") negativeCorrelation a(CHEBI:Anatabine)
pubmed:30740335 bp(GO:"inflammatory response") increases path(MESH:"Protein Unfolding")
pubmed:23746257 bp(GO:"inflammatory response") association bp(CONSO:Proteostasis)
pubmed:24563850 bp(GO:"inflammatory response") increases a(CHEBI:"reactive oxygen species")
pubmed:16566606 bp(GO:"inflammatory response") increases a(CHEBI:"reactive oxygen species")
pubmed:8940412 bp(GO:"inflammatory response") positiveCorrelation act(p(RGD:Crh))
pubmed:8940412 bp(GO:"inflammatory response") negativeCorrelation a(CHEBI:antalarmin)
pubmed:30126037 bp(GO:"inflammatory response") association bp(GO:"cellular senescence")
pubmed:18494933 bp(GO:"inflammatory response") increases tloc(p(HGNC:DKK1), fromLoc(go:0005622 ! intracellular), toLoc(go:0005615 ! "extracellular space"))
pubmed:18494933 bp(GO:"inflammatory response") positiveCorrelation p(HGNC:S100B)
pubmed:16566606 bp(GO:"inflammatory response") increases a(CHEBI:"reactive nitrogen species")
pubmed:16566606 bp(GO:"inflammatory response") increases a(CHEBI:peroxynitrite)
pubmed:30988501 bp(GO:"inflammatory response") increases bp(GO:"microglial cell activation")
pubmed:30988501 bp(GO:"inflammatory response") increases bp(MESH:"Transendothelial and Transepithelial Migration")
pubmed:30988501 bp(GO:"inflammatory response") increases act(a(MESH:T-Lymphocytes))
pubmed:30046111 bp(GO:"phospholipid metabolic process") association bp(GO:aging)
pubmed:30046111 bp(GO:"extracellular matrix organization") association bp(GO:aging)
pubmed:30046111 bp(GO:"cell adhesion") association bp(GO:aging)
pubmed:21214928 bp(GO:"cell adhesion") association p(HGNC:APP)
pubmed:27190210 bp(GO:"cell adhesion") association p(HGNC:CHRNA7)
pubmed:28901280 bp(GO:"cell adhesion") association a(MESH:Acetylcholine)
pubmed:30106381 bp(GO:"cell adhesion") association p(HGNC:ADNP)
pubmed:30106381 bp(GO:"cell adhesion") association a(PUBCHEM:9832404)
pubmed:30046111 bp(GO:"endothelial tube morphogenesis") association bp(GO:aging)
pubmed:10998059 act(p(MGI:Cdk5r1)) increases p(MGI:Ppp1r1b, pmod(go:0006468 ! "protein phosphorylation"))
pubmed:19118186 p(MGI:Cdk5r1) increases act(p(MGI:Cdk5))
pubmed:27087442 p(MGI:Cdk5r1) decreases bp(GO:"neuron death")
pubmed:30046111 p(MGI:Vegfc) increases a(MESH:"Lymphatic Vessels")
pubmed:30046111 p(MGI:Vegfc) increases act(a(MESH:"Lymphatic Vessels"))
pubmed:30046111 p(MGI:Vegfc) increases a(MESH:"Lymphatic Vessels")
pubmed:30046111 p(MGI:Vegfc) increases a(MESH:"Lymphatic Vessels")
pubmed:30046111 p(MGI:Vegfc) increases act(a(MESH:"Lymphatic Vessels"))
pubmed:30046111 p(MGI:Vegfc) causesNoChange a(MESH:"Lymphatic Vessels")
pubmed:30046111 p(MGI:Vegfc) increases path(MESH:"Spatial Learning")
pubmed:30046111 p(MGI:Vegfc) increases bp(GO:"stem cell proliferation")
pubmed:30046111 p(MGI:Vegfc) increases bp(GO:cognition)
pubmed:30046111 p(MGI:Vegfc) increases tloc(a(CHEBI:macromolecule), fromLoc(MESH:"Cerebrospinal Fluid"), toLoc(MESH:"Lymph Nodes"))
pubmed:30046111 p(MGI:Vegfc) causesNoChange tloc(a(CHEBI:macromolecule), fromLoc(MESH:"Cerebrospinal Fluid"), toLoc(MESH:"Lymph Nodes"))
pubmed:30046111 p(MGI:Vegfc) causesNoChange a(CHEBI:amyloid-beta)
pubmed:30046111 p(MGI:Vegfc) causesNoChange path(HP:"Abnormal lymphatic vessel morphology")
pubmed:30046111 composite(a(CHEBI:"poly(ethylene glycol dimethacrylate)"), p(MGI:Vegfc)) increases a(MESH:"Lymphatic Vessels")
pubmed:30046111 p(MGI:Vegfc, var("p.Cys156Ser")) increases a(MESH:"Lymphatic Vessels")
pubmed:30046111 p(MGI:Vegfc, var("p.Cys156Ser")) increases tloc(a(CHEBI:macromolecule), fromLoc(MESH:"Cerebrospinal Fluid"), toLoc(MESH:Brain))
pubmed:30046111 path(MESH:Inflammation) negativeCorrelation act(a(MESH:"Lymphatic Vessels"))
pubmed:21329555 path(MESH:Inflammation) positiveCorrelation path(MESH:"Alzheimer Disease")
pubmed:27288790 path(MESH:Inflammation) positiveCorrelation path(MESH:"Alzheimer Disease")
pubmed:24027553 path(MESH:Inflammation) positiveCorrelation path(MESH:"Alzheimer Disease")
pubmed:21329555 path(MESH:Inflammation) association bp(GO:"NIK/NF-kappaB signaling")
pubmed:27288790 path(MESH:Inflammation) association p(FPLX:NFkappaB)
pubmed:27794524 path(MESH:Inflammation) directlyDecreases path(MESH:"Epstein-Barr Virus Infections")
pubmed:27794524 path(MESH:Inflammation) association bp(GO:"microglial cell activation")
pubmed:30967783 path(MESH:Inflammation) increases bp(GO:"microglial cell activation")
pubmed:30988501 path(MESH:Inflammation) increases bp(GO:"microglial cell activation")
pubmed:27956442 path(MESH:Inflammation) association path(MESH:"Multiple Sclerosis")
pubmed:27956442 path(MESH:Inflammation) association path(MESH:"Demyelinating Diseases")
pubmed:27956442 path(MESH:Inflammation) association path(MESH:"Multiple Sclerosis, Relapsing-Remitting")
pubmed:27956442 path(MESH:Inflammation) negativeCorrelation path(MESH:"Energy Metabolism")
pubmed:27956442 path(MESH:Inflammation) directlyIncreases path(NCIT:C95603)
pubmed:30967783 path(MESH:Inflammation) increases act(a(MESH:Microglia, loc(NCIT:C74601)))
pubmed:30967783 path(MESH:Inflammation) increases act(a(MESH:Macrophages, loc(MESH:"Choroid Plexus")))
pubmed:30967783 path(MESH:Inflammation) increases act(a(MESH:Macrophages, loc(NCIT:C83196)))
pubmed:30967783 path(MESH:Inflammation) increases act(a(MESH:Macrophages, loc(MESH:Meninges)))
pubmed:30967783 path(MESH:Inflammation) association p(HGNC:TREM2)
pubmed:30967783 path(MESH:Inflammation) increases bp(GO:"macrophage activation")
pubmed:30967783 path(MESH:Inflammation) increases path(DOID:"multiple sclerosis")
pubmed:27190210 path(MESH:Inflammation) association p(HGNC:CHRNA7)
pubmed:29428175 path(MESH:Inflammation) association act(p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits"))
pubmed:29428175 path(MESH:Inflammation) association a(CHEBI:"cholinergic agonist")
pubmed:26979166 path(MESH:Inflammation) increases path(DOID:"mental depression")
pubmed:26979166 path(MESH:Inflammation) association p(HGNC:CHI3L1)
pubmed:26979166 path(MESH:Inflammation) association p(HGNC:CCL2)
pubmed:26979166 path(MESH:Inflammation) increases deg(a(MESH:"Cholinergic Neurons"))
pubmed:22040696 path(MESH:Inflammation) increases path(MESH:"Renal Insufficiency")
pubmed:30106381 path(MESH:Inflammation) association p(HGNC:ADNP)
pubmed:30012004 path(MESH:Inflammation) positiveCorrelation path(MESH:"Huntington Disease")
pubmed:24027553 path(MESH:Inflammation) increases act(p(HGNCGENEFAMILY:Caspases))
pubmed:26195256 path(MESH:Inflammation) increases p(HGNC:MAPT, pmod(CONSO:hyperphosphorylation))
pubmed:26195256 path(MESH:Inflammation) decreases deg(a(CHEBI:amyloid-beta))
pubmed:30988501 path(MESH:Inflammation) increases path(CONSO:neurotoxicity)
pubmed:30988501 path(MESH:Inflammation) increases path(CONSO:Neurodegeneration)
pubmed:30988501 path(MESH:Inflammation) decreases bp(GO:cognition)
pubmed:30988501 path(MESH:Inflammation) decreases bp(GO:cognition)
pubmed:30988501 path(MESH:Inflammation) association bp(GO:cognition)
pubmed:30988501 path(MESH:Inflammation) decreases bp(GO:cognition)
pubmed:30988501 path(MESH:Inflammation) increases path(MESH:"Signs and Symptoms")
pubmed:30988501 path(MESH:Inflammation) association path(DOID:obesity)
pubmed:30988501 path(MESH:Inflammation) decreases act(a(MESH:Neurons))
pubmed:30988501 path(MESH:Inflammation) increases deg(a(MESH:Neurons))
pubmed:30988501 path(MESH:Inflammation) decreases a(MESH:"Blood-Brain Barrier")
pubmed:30988501 path(MESH:Inflammation) increases act(a(MESH:"Central Nervous System"))
pubmed:30988501 path(MESH:Inflammation) increases path(DOID:"learning disability")
pubmed:30988501 path(MESH:Inflammation) decreases bp(GO:"learning or memory")
pubmed:30988501 path(MESH:Inflammation) decreases path(MESH:Attention)
pubmed:30988501 path(MESH:Inflammation) increases deg(a(GO:"myelin sheath"))
pubmed:30988501 path(MESH:Inflammation) increases path(MESH:Recurrence)
pubmed:29255009 p(MGI:Fkbp1b) increases path(MESH:Memory)
pubmed:29255009 p(MGI:Fkbp1b) increases bp(MESH:Aging)
pubmed:29255009 p(MGI:Fkbp1b) increases act(p(MGI:Eif3g))
pubmed:29255009 p(MGI:Fkbp1b) increases act(p(MGI:Pla2g7))
pubmed:29255009 p(MGI:Fkbp1b) increases act(p(MGI:S100b))
pubmed:29255009 p(MGI:Fkbp1b) increases act(p(MGI:Snapc2))
pubmed:29255009 p(MGI:Fkbp1b) increases bp(MESH:"Facilitated Diffusion")
pubmed:29255009 p(MGI:Fkbp1b) increases bp(GO:"ectoderm development")
pubmed:29255009 p(MGI:Fkbp1b) increases bp(GO:"regulation of actin cytoskeleton organization")
pubmed:29255009 p(MGI:Fkbp1b) increases act(p(MESH:"Mitogen-Activated Protein Kinases"))
pubmed:29255009 p(MGI:Fkbp1b) decreases act(p(MESH:"Membrane Transport Proteins"))
pubmed:29255009 p(MGI:Fkbp1b) decreases bp(GO:"blood vessel development")
pubmed:29255009 p(MGI:Fkbp1b) decreases bp(GO:"regulation of cellular component movement")
pubmed:29255009 p(MGI:Fkbp1b) decreases a(GO:"cytoplasmic vesicle")
pubmed:29255009 p(MGI:Fkbp1b) increases p(MGI:Map2)
pubmed:29255009 p(MGI:Fkbp1b) negativeCorrelation a(CHEBI:"calcium(2+)")
pubmed:29255009 p(MGI:Fkbp1b) increases p(MGI:Capn1)
pubmed:29255009 p(MGI:Fkbp1b) increases p(MGI:Ppp3cc)
pubmed:29255009 p(MGI:Fkbp1b) increases p(MGI:Orai1)
pubmed:29255009 p(MGI:Fkbp1b) decreases p(MGI:Hif1an)
pubmed:29255009 p(MGI:Fkbp1b) decreases p(MGI:Nfkb1)
pubmed:24762290 path(MESH:Memory) association path(MESH:"Parkinson Disease")
pubmed:24762290 path(MESH:Memory) association complex(CONSO:"alpha-4 beta-2 nAChR")
pubmed:18986241 path(MESH:Memory) association path(MESH:"Cholinergic Neurons")
pubmed:28901280 path(MESH:Memory) association p(MESH:"Receptors, Nicotinic")
pubmed:29255009 p(CONSO:AAV-FKBP1B) increases p(MGI:Fkbp1b, loc(MESH:Hippocampus))
pubmed:29255009 p(CONSO:AAV-FKBP1B) increases g(MGI:Fkbp1b, loc(MESH:Hippocampus))
pubmed:29255009 bp(MESH:Aging) decreases p(MGI:Map2)
pubmed:29255009 bp(MESH:Aging) decreases p(MGI:Capn1)
pubmed:29255009 bp(MESH:Aging) decreases p(MGI:Ppp3cc)
pubmed:29255009 bp(MESH:Aging) decreases p(MGI:Orai1)
pubmed:24511233 bp(MESH:Aging) association path(MESH:"Alzheimer Disease")
pubmed:23528736 bp(MESH:Aging) increases path(MESH:"Alzheimer Disease")
pubmed:25437566 bp(MESH:Aging) increases p(HGNC:TPR)
pubmed:25437566 bp(MESH:Aging) increases p(HGNC:TPR)
pubmed:25437566 bp(MESH:Aging) increases p(HGNC:TPR)
pubmed:27491084 bp(MESH:Aging) increases p(HGNC:TPR)
pubmed:25437566 bp(MESH:Aging) decreases p(HGNCGENEFAMILY:"DNAJ (HSP40) heat shock proteins")
pubmed:25437566 bp(MESH:Aging) decreases p(HGNCGENEFAMILY:"DNAJ (HSP40) heat shock proteins")
pubmed:25437566 bp(MESH:Aging) decreases p(HGNCGENEFAMILY:"DNAJ (HSP40) heat shock proteins")
pubmed:25437566 bp(MESH:Aging) decreases p(HGNCGENEFAMILY:"DNAJ (HSP40) heat shock proteins")
pubmed:27491084 bp(MESH:Aging) decreases p(HGNCGENEFAMILY:"DNAJ (HSP40) heat shock proteins")
pubmed:25784053 bp(MESH:Aging) decreases p(HGNCGENEFAMILY:"DNAJ (HSP40) heat shock proteins")
pubmed:25437566 bp(MESH:Aging) decreases p(FPLX:HSPA)
pubmed:25437566 bp(MESH:Aging) decreases p(FPLX:HSPA)
pubmed:27491084 bp(MESH:Aging) decreases p(FPLX:HSPA)
pubmed:25784053 bp(MESH:Aging) decreases p(FPLX:HSPA)
pubmed:25437566 bp(MESH:Aging) increases p(FPLX:HSPB)
pubmed:25437566 bp(MESH:Aging) increases p(FPLX:HSPB)
pubmed:27491084 bp(MESH:Aging) increases p(FPLX:HSPB)
pubmed:25784053 bp(MESH:Aging) increases p(FPLX:HSPB)
pubmed:25437566 bp(MESH:Aging) decreases p(HGNC:HSPD1)
pubmed:27491084 bp(MESH:Aging) decreases p(HGNC:HSPD1)
pubmed:25437566 bp(MESH:Aging) increases p(HGNC:HSPA2)
pubmed:25437566 bp(MESH:Aging) increases p(HGNC:DNAJB2)
pubmed:25437566 bp(MESH:Aging) decreases p(HGNC:HSPA12A)
pubmed:25437566 bp(MESH:Aging) decreases p(HGNC:TOMM70)
pubmed:25437566 bp(MESH:Aging) decreases p(HGNC:HSP90AB1)
pubmed:25437566 bp(MESH:Aging) decreases p(HGNC:HSPA8)
pubmed:25437566 bp(MESH:Aging) decreases p(HGNC:HSPA14)
pubmed:25437566 bp(MESH:Aging) decreases p(HGNC:TCP1)
pubmed:25784053 bp(MESH:Aging) regulates bp(CONSO:Proteostasis)
pubmed:25784053 bp(MESH:Aging) decreases p(FPLX:HSP90)
pubmed:29311797 bp(MESH:Aging) increases p(FPLX:HSP90)
pubmed:29311797 bp(MESH:Aging) decreases p(FPLX:HSP90)
pubmed:29311797 bp(MESH:Aging) decreases p(FPLX:HSP90)
pubmed:25784053 bp(MESH:Aging) decreases p(FPLX:"CCT_complex")
pubmed:23528736 bp(MESH:Aging) decreases bp(GO:autophagy)
pubmed:23528736 bp(MESH:Aging) decreases bp(GO:"proteasome-mediated ubiquitin-dependent protein catabolic process")
pubmed:28420982 bp(MESH:Aging) association tloc(p(HGNC:MAPT), fromLoc(GO:axon), toLoc(GO:"cell body"))
pubmed:28420982 bp(MESH:Aging) association tloc(p(HGNC:MAPT), fromLoc(GO:axon), toLoc(GO:dendrite))
pubmed:29311797 bp(MESH:Aging) association path(MESH:"Neurodegenerative Diseases")
pubmed:29311797 bp(MESH:Aging) decreases bp(GO:"protein folding")
pubmed:29311797 bp(MESH:Aging) increases path(MESH:"Protein Aggregation, Pathological")
pubmed:29311797 bp(MESH:Aging) decreases bp(MESH:Proteolysis)
pubmed:29311797 bp(MESH:Aging) decreases act(p(FPLX:Proteasome))
pubmed:29311797 bp(MESH:Aging) decreases act(p(FPLX:Proteasome))
pubmed:29311797 bp(MESH:Aging) decreases bp(GO:"chaperone-mediated autophagy")
pubmed:29311797 bp(MESH:Aging) decreases bp(GO:"chaperone-mediated autophagy")
pubmed:29311797 bp(MESH:Aging) decreases p(HGNC:PPID)
pubmed:29311797 bp(MESH:Aging) decreases p(HGNC:PPID)
pubmed:29311797 bp(MESH:Aging) increases p(HGNC:FKBP5)
pubmed:29311797 bp(MESH:Aging) increases p(HGNC:FKBP5)
pubmed:29311797 bp(MESH:Aging) decreases p(HGNC:PPP5C)
pubmed:29311797 bp(MESH:Aging) decreases p(HGNC:PPP5C)
pubmed:29311797 bp(MESH:Aging) decreases p(HGNC:AHSA1)
pubmed:29311797 bp(MESH:Aging) decreases p(HGNC:AHSA1)
pubmed:29311797 bp(MESH:Aging) decreases p(HGNC:FKBP4)
pubmed:29311797 bp(MESH:Aging) decreases p(HGNC:STIP1)
pubmed:29311797 bp(MESH:Aging) decreases p(HGNC:PTGES3)
pubmed:29311797 bp(MESH:Aging) increases p(FPLX:HSP90, pmod(go:0006468 ! "protein phosphorylation"))
pubmed:29311797 bp(MESH:Aging) increases p(FPLX:HSP90, pmod(go:0006473 ! "protein acetylation"))
pubmed:29311797 bp(MESH:Aging) increases p(FPLX:HSP90, pmod(go:0017014 ! "protein nitrosylation"))
pubmed:29311797 bp(MESH:Aging) increases p(FPLX:HSP90, pmod(go:0016567 ! "protein ubiquitination"))
pubmed:29255009 p(MGI:Eif3g) increases bp(MESH:Aging)
pubmed:29255009 p(MGI:Pla2g7) increases bp(MESH:Aging)
pubmed:29255009 p(MGI:S100b) increases bp(MESH:Aging)
pubmed:29255009 p(MGI:Snapc2) increases bp(MESH:Aging)
pubmed:29255009 path(MESH:Aging) decreases bp(MESH:"Facilitated Diffusion")
pubmed:29255009 path(MESH:Aging) decreases bp(GO:"ectoderm development")
pubmed:29255009 path(MESH:Aging) decreases bp(GO:"regulation of actin cytoskeleton organization")
pubmed:29255009 path(MESH:Aging) decreases act(p(MESH:"Mitogen-Activated Protein Kinases"))
pubmed:29255009 path(MESH:Aging) increases act(p(MESH:"Membrane Transport Proteins"))
pubmed:29255009 path(MESH:Aging) increases bp(GO:"blood vessel development")
pubmed:29255009 path(MESH:Aging) increases bp(GO:"regulation of cellular component movement")
pubmed:29255009 path(MESH:Aging) increases a(GO:"cytoplasmic vesicle")
pubmed:29255009 path(MESH:Aging) increases p(MGI:Hif1an)
pubmed:29255009 path(MESH:Aging) increases p(MGI:Nfkb1)
pubmed:27794524 path(MESH:Aging) decreases path(MESH:Inflammation)
pubmed:27794524 path(MESH:Aging) increases path(MESH:"Neurodegenerative Diseases")
pubmed:19126755 path(MESH:Aging) negativeCorrelation p(CONSO:"alpha-4 beta-2 nAChR")
pubmed:19126755 path(MESH:Aging) negativeCorrelation p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits")
pubmed:19126755 path(MESH:Aging) decreases p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits")
pubmed:19126755 path(MESH:Aging) decreases p(MGI:Chrna4)
pubmed:19126755 path(MESH:Aging) negativeCorrelation p(MGI:Chrna4)
pubmed:19126755 path(MESH:Aging) negativeCorrelation p(MGI:Chrna7)
pubmed:18986241 path(MESH:Aging) association bp(MESH:"Oxidative Stress")
pubmed:30362565 path(MESH:Aging) increases path(MESH:"Motor Skills Disorders")
pubmed:30362565 path(MESH:Aging) increases path(MESH:Ataxia)
pubmed:26195256 path(MESH:Aging) increases path(MESH:"Alzheimer Disease")
pubmed:26195256 path(MESH:Aging) negativeCorrelation a(MESH:"Cerebrospinal Fluid")
pubmed:26195256 path(MESH:Aging) negativeCorrelation act(p(HGNC:AQP1))
pubmed:26091809 path(MESH:Aging) positiveCorrelation p(HGNC:TARDBP)
pubmed:29255009 a(CHEBI:"calcium(2+)") negativeCorrelation p(MGI:Fkbp1b)
pubmed:24107444 a(CHEBI:"calcium(2+)") positiveCorrelation bp(GO:"long-term synaptic potentiation")
pubmed:24107444 a(CHEBI:"calcium(2+)") positiveCorrelation bp(MESH:"Neuronal Plasticity")
pubmed:19126755 a(CHEBI:"calcium(2+)", loc(GO:intracellular)) regulates bp(MESH:"Neuronal Plasticity")
pubmed:29428175 tloc(a(CHEBI:"calcium(2+)"), fromLoc(GO:"endoplasmic reticulum"), toLoc(MESH:Cytoplasm)) increases bp(MESH:"Neuronal Plasticity")
pubmed:24107444 a(CHEBI:"calcium(2+)") positiveCorrelation tloc(a(CHEBI:"L-glutamic acid"), fromLoc(go:0005622 ! intracellular), toLoc(go:0005615 ! "extracellular space"))
pubmed:31346362 a(CHEBI:"calcium(2+)", loc(MESH:Cytosol)) increases bp(GO:"membrane lipid catabolic process")
pubmed:31346362 a(CHEBI:"calcium(2+)", loc(MESH:Cytosol)) increases act(p(HGNCGENEFAMILY:Calpains))
pubmed:24027553 a(CHEBI:"calcium(2+)") increases act(p(HGNCGENEFAMILY:Calpains))
pubmed:24027553 a(CHEBI:"calcium(2+)", loc(GO:intracellular)) increases act(p(HGNCGENEFAMILY:Calpains))
pubmed:24027553 a(CHEBI:"calcium(2+)", loc(GO:intracellular)) increases act(p(HGNCGENEFAMILY:Calpains))
pubmed:31346362 a(CHEBI:"calcium(2+)", loc(MESH:Cytosol)) increases act(p(MESH:Deoxyribonucleases))
pubmed:27794524 a(CHEBI:"calcium(2+)", loc(GO:axon)) directlyIncreases path(MESH:"Neurodegenerative Diseases")
pubmed:27794524 a(CHEBI:"calcium(2+)", loc(GO:axon)) increases a(MESH:Calpain)
pubmed:27794524 a(CHEBI:"calcium(2+)", loc(GO:axon)) increases a(MESH:Phospholipases)
pubmed:27794524 a(CHEBI:"calcium(2+)", loc(GO:axon)) negativeCorrelation p(MESH:"Microtubule Proteins", pmod(go:0006468 ! "protein phosphorylation"))
pubmed:27794524 a(CHEBI:"calcium(2+)", loc(GO:axon)) negativeCorrelation p(MESH:"Neurofilament Proteins", pmod(go:0006468 ! "protein phosphorylation"))
pubmed:19126755 a(CHEBI:"calcium(2+)", loc(GO:intracellular)) increases act(p(FPLX:CREB), ma(go:0001071 ! "nucleic acid binding transcription factor activity"))
pubmed:19126755 a(CHEBI:"calcium(2+)", loc(GO:intracellular)) increases a(CHEBI:anandamide)
pubmed:19126755 a(CHEBI:"calcium(2+)", loc(GO:intracellular)) regulates bp(GO:"signal release")
pubmed:19126755 a(CHEBI:"calcium(2+)", loc(GO:intracellular)) regulates bp(GO:"neuron migration")
pubmed:22040696 tloc(a(CHEBI:"calcium(2+)"), fromLoc(MESH:"Extracellular Space"), toLoc(MESH:Cytoplasm)) increases bp(GO:"neuron migration")
pubmed:19126755 a(CHEBI:"calcium(2+)", loc(GO:intracellular)) regulates bp(GO:"neuron differentiation")
pubmed:19293145 a(CHEBI:"calcium(2+)") association act(p(HGNCGENEFAMILY:"Inositol 1,4,5-triphosphate receptors"))
pubmed:23038257 a(CHEBI:"calcium(2+)") increases act(p(MESH:"Receptors, Nicotinic"))
pubmed:17009926 tloc(a(CHEBI:"calcium(2+)"), fromLoc(MESH:"Extracellular Space"), toLoc(MESH:"Intracellular Space")) increases tloc(a(CHEBI:"calcium(2+)"), fromLoc(MESH:"Intracellular Space"), toLoc(GO:cytosol))
pubmed:26472524 tloc(a(CHEBI:"calcium(2+)"), fromLoc(MESH:"Extracellular Space"), toLoc(MESH:"Intracellular Space")) increases bp(GO:"membrane depolarization")
pubmed:20556492 a(CHEBI:"calcium(2+)") regulates bp(GO:"membrane depolarization")
pubmed:26472524 a(CHEBI:"calcium(2+)") regulates act(p(FPLX:CHRN))
pubmed:26813123 a(CHEBI:"calcium(2+)") regulates p(FPLX:CHRN)
pubmed:26813123 a(CHEBI:"calcium(2+)") increases tloc(a(CHEBI:"glutamate(2-)"), fromLoc(GO:intracellular), toLoc(GO:"extracellular region"))
pubmed:26813123 a(CHEBI:"calcium(2+)") increases tloc(a(CHEBI:"gamma-aminobutyric acid"), fromLoc(GO:intracellular), toLoc(GO:"extracellular region"))
pubmed:26813123 a(CHEBI:"calcium(2+)") increases tloc(a(CHEBI:dopamine), fromLoc(GO:intracellular), toLoc(GO:"extracellular region"))
pubmed:26813123 a(CHEBI:"calcium(2+)") increases tloc(a(CHEBI:serotonin), fromLoc(GO:intracellular), toLoc(GO:"extracellular region"))
pubmed:26813123 a(CHEBI:"calcium(2+)") increases tloc(a(CHEBI:noradrenaline), fromLoc(GO:intracellular), toLoc(GO:"extracellular region"))
pubmed:26813123 a(CHEBI:"calcium(2+)") increases tloc(a(CHEBI:acetylcholine), fromLoc(GO:intracellular), toLoc(GO:"extracellular region"))
pubmed:29428175 a(CHEBI:"calcium(2+)", loc(MESH:Cytoplasm)) regulates tloc(a(CHEBI:neurotransmitter), fromLoc(go:0005622 ! intracellular), toLoc(go:0005615 ! "extracellular space"))
pubmed:29428175 a(CHEBI:"calcium(2+)", loc(MESH:"Endoplasmic Reticulum")) increases p(HGNC:CAMK2A)
pubmed:29428175 a(CHEBI:"calcium(2+)", loc(MESH:"Endoplasmic Reticulum")) increases a(CHEBI:calcineurin)
pubmed:29428175 tloc(a(CHEBI:"calcium(2+)", loc(MESH:"Endoplasmic Reticulum")), fromLoc(go:0005622 ! intracellular), toLoc(go:0005615 ! "extracellular space")) decreases act(p(HGNC:MAPK14))
pubmed:29428175 tloc(a(CHEBI:"calcium(2+)", loc(MESH:"Endoplasmic Reticulum")), fromLoc(go:0005622 ! intracellular), toLoc(go:0005615 ! "extracellular space")) decreases tloc(p(HGNC:TNF), fromLoc(go:0005622 ! intracellular), toLoc(go:0005615 ! "extracellular space"))
pubmed:29428175 tloc(a(CHEBI:"calcium(2+)", loc(MESH:"Endoplasmic Reticulum")), fromLoc(go:0005622 ! intracellular), toLoc(go:0005615 ! "extracellular space")) decreases p(HGNC:NFKB1)
pubmed:29428175 tloc(a(CHEBI:"calcium(2+)", loc(MESH:"Endoplasmic Reticulum")), fromLoc(go:0005622 ! intracellular), toLoc(go:0005615 ! "extracellular space")) decreases p(HGNC:IFNG)
pubmed:26088141 a(CHEBI:"calcium(2+)") association act(a(MESH:"Calcium Channels"))
pubmed:19721446 a(CHEBI:"calcium(2+)") increases act(p(HGNC:CHRNA7))
pubmed:19721446 a(CHEBI:"calcium(2+)") increases act(p(CONSO:"alpha-4 beta-2 nAChR"))
pubmed:20556492 a(CHEBI:"calcium(2+)") regulates complex(GO:"mitochondrial permeability transition pore complex")
pubmed:26968346 a(CHEBI:"calcium(2+)", loc(GO:cytoplasm)) increases act(complex(GO:"calcineurin complex"))
pubmed:27299292 tloc(a(CHEBI:"calcium(2+)"), fromLoc(go:0005622 ! intracellular), toLoc(go:0005615 ! "extracellular space")) regulates act(p(HGNC:PPP3CA), ma(go:0016791 ! "phosphatase activity"))
pubmed:2123288 a(CHEBI:"calcium(2+)") increases act(p(FPLX:CALM))
pubmed:2833519 a(CHEBI:"calcium(2+)") increases act(p(HGNC:S100B))
pubmed:10537045 a(CHEBI:"calcium(2+)") positiveCorrelation complex(p(HGNC:MAPT), p(HGNC:TGM2))
pubmed:30837838 a(CHEBI:"calcium(2+)") association bp(GO:"neuron fate commitment")
pubmed:30837838 a(CHEBI:"calcium(2+)") association path(MESH:"Nerve Degeneration")
pubmed:30837838 a(CHEBI:"calcium(2+)") increases bp(GO:"neuron death")
pubmed:23702978 a(CHEBI:"calcium(2+)") association p(HGNC:MAP3K7)
pubmed:23702978 tloc(a(CHEBI:"calcium(2+)"), fromLoc(MESH:"Extracellular Space"), toLoc(MESH:"Intracellular Space")) increases act(p(HGNC:NLRP3))
pubmed:19118186 p(MGI:Capn1) negativeCorrelation p(MGI:Ttbk1)
pubmed:29255009 a(CHEBI:sirolimus) decreases bp(CONSO:"PI3K-Akt signaling pathway")
pubmed:29661268 a(CHEBI:sirolimus) increases p(HGNC:ULK1, pmod(go:0006468 ! "protein phosphorylation"))
pubmed:29661268 a(CHEBI:sirolimus) negativeCorrelation bp(GO:autophagy)
pubmed:30061532 a(CHEBI:sirolimus) increases bp(GO:autophagy)
pubmed:30688256 a(CHEBI:sirolimus) increases bp(GO:autophagy)
pubmed:26968346 a(CHEBI:sirolimus) positiveCorrelation bp(GO:autophagy)
pubmed:29758300 a(CHEBI:sirolimus) increases bp(GO:autophagy)
pubmed:22908190 a(CHEBI:sirolimus) increases bp(GO:autophagy)
pubmed:22908190 a(CHEBI:sirolimus) increases bp(GO:autophagy)
pubmed:18930136 a(CHEBI:sirolimus) increases bp(GO:autophagy)
pubmed:30116051 a(CHEBI:sirolimus) increases bp(GO:autophagy)
pubmed:23528736 a(CHEBI:sirolimus) increases bp(GO:autophagy)
pubmed:29626319 a(CHEBI:sirolimus) increases bp(GO:autophagy)
pubmed:27181519 a(CHEBI:sirolimus) increases bp(GO:autophagy)
pubmed:29661268 a(CHEBI:sirolimus) negativeCorrelation act(p(HGNC:PPP2CA))
pubmed:30061532 a(CHEBI:sirolimus) decreases p(HGNC:MAPT, pmod(CONSO:hyperphosphorylation))
pubmed:30061532 a(CHEBI:sirolimus) decreases p(HGNC:SNCA, pmod(CONSO:misfolded))
pubmed:30061532 a(CHEBI:sirolimus) decreases p(HGNC:TARDBP, pmod(CONSO:misfolded))
pubmed:30061532 a(CHEBI:sirolimus) increases path(MESH:"Interpersonal Relations")
pubmed:30061532 a(CHEBI:sirolimus) increases bp(GO:behavior)
pubmed:30061532 a(CHEBI:sirolimus) decreases act(a(CHEBI:methamphetamine))
pubmed:30061532 a(CHEBI:sirolimus) decreases path(MESH:"Psychotic Disorders")
pubmed:30061532 a(CHEBI:sirolimus) decreases path(MESH:"Psychotic Disorders")
pubmed:30061532 a(CHEBI:sirolimus) decreases path(MESH:Schizophrenia)
pubmed:30688256 a(CHEBI:sirolimus) decreases path(MESH:"Neurodegenerative Diseases")
pubmed:30688256 a(CHEBI:sirolimus) increases a(HBP:"huntingtin aggregates")
pubmed:26968346 a(CHEBI:sirolimus) decreases p(HGNC:MTOR)
pubmed:29758300 a(CHEBI:sirolimus) decreases act(p(HGNC:MTOR))
pubmed:18930136 a(CHEBI:sirolimus) decreases act(p(HGNC:MTOR))
pubmed:30985105 a(CHEBI:sirolimus) decreases act(p(HGNC:MTOR))
pubmed:30837838 a(CHEBI:sirolimus) decreases p(HGNC:MTOR)
pubmed:26968346 a(CHEBI:sirolimus) increases p(HGNC:TFEB)
pubmed:26968346 a(CHEBI:sirolimus) decreases act(p(HGNC:SNCA, var("?")))
pubmed:26968346 a(CHEBI:sirolimus) decreases p(CONSO:PrPSc)
pubmed:27299292 a(CHEBI:sirolimus) increases composite(a(CHEBI:sirolimus), p(HGNC:TFEB, frag("?_*")))
pubmed:29758300 a(CHEBI:sirolimus) increases bp(GO:cognition)
pubmed:29758300 a(CHEBI:sirolimus) decreases a(CHEBI:amyloid-beta)
pubmed:29758300 a(CHEBI:sirolimus) decreases a(CHEBI:amyloid-beta)
pubmed:22908190 a(CHEBI:sirolimus) decreases a(CHEBI:amyloid-beta)
pubmed:29626319 a(CHEBI:sirolimus) decreases a(CHEBI:amyloid-beta)
pubmed:29758300 a(CHEBI:sirolimus) increases bp(GO:macroautophagy)
pubmed:29758300 a(CHEBI:sirolimus) increases bp(GO:macroautophagy)
pubmed:26751493 a(CHEBI:sirolimus) increases bp(GO:macroautophagy)
pubmed:29758300 a(CHEBI:sirolimus) decreases p(HGNC:MAPT)
pubmed:23528736 a(CHEBI:sirolimus) increases deg(p(HGNC:MAPT))
pubmed:29758300 a(CHEBI:sirolimus) increases bp(GO:"motor behavior")
pubmed:27181519 a(CHEBI:sirolimus) increases bp(GO:"motor behavior")
pubmed:22908190 a(CHEBI:sirolimus) decreases path(MESH:Tauopathies)
pubmed:22908190 a(CHEBI:sirolimus) decreases path(MESH:Tauopathies)
pubmed:25784053 a(CHEBI:sirolimus) decreases act(p(FPLX:mTORC1))
pubmed:25784053 a(CHEBI:sirolimus) decreases path(MESH:"Protein Aggregation, Pathological")
pubmed:25784053 a(CHEBI:sirolimus) decreases path(MESH:"Huntington Disease")
pubmed:18930136 a(CHEBI:sirolimus) decreases path(MESH:"Huntington Disease")
pubmed:25784053 a(CHEBI:sirolimus) decreases path(MESH:"Machado-Joseph Disease")
pubmed:25784053 a(CHEBI:sirolimus) decreases path(MESH:"Alzheimer Disease")
pubmed:25784053 a(CHEBI:sirolimus) decreases path(MESH:"Parkinson Disease")
pubmed:25784053 a(CHEBI:sirolimus) decreases path(MESH:"Amyotrophic Lateral Sclerosis")
pubmed:18930136 a(CHEBI:sirolimus) decreases path(MESH:"Bulbo-Spinal Atrophy, X-Linked")
pubmed:27594586 a(CHEBI:sirolimus) decreases bp(GO:"TOR signaling")
pubmed:27594586 a(CHEBI:sirolimus) increases r(HGNC:MMP9)
pubmed:27594586 a(CHEBI:sirolimus) increases r(HGNC:MMP2)
pubmed:30116051 a(CHEBI:sirolimus) decreases p(HGNC:SNCA)
pubmed:30985105 a(CHEBI:sirolimus) decreases p(HGNC:SNCA)
pubmed:27181519 a(CHEBI:sirolimus) increases deg(p(HGNC:SNCA))
pubmed:30116051 a(CHEBI:sirolimus) decreases p(HGNC:FUS)
pubmed:27181519 a(CHEBI:sirolimus) decreases p(HGNC:FUS, loc(GO:"cytoplasmic stress granule"))
pubmed:30116051 a(CHEBI:sirolimus) decreases p(HGNC:HTT)
pubmed:27181519 a(CHEBI:sirolimus) increases deg(p(HGNC:HTT))
pubmed:24027553 a(CHEBI:sirolimus) increases bp(MESH:Autophagy)
pubmed:29626319 a(CHEBI:sirolimus) decreases p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation"))
pubmed:27181519 a(CHEBI:sirolimus) increases deg(complex(GO:"cytoplasmic stress granule"))
pubmed:27181519 a(CHEBI:sirolimus) increases bp(GO:locomotion)
pubmed:27181519 a(CHEBI:sirolimus) increases a(MESH:Neurites)
pubmed:27181519 a(CHEBI:sirolimus) decreases bp(GO:"cell death")
pubmed:30837838 a(CHEBI:sirolimus) increases path(MESH:Autophagy)
pubmed:30837838 a(CHEBI:sirolimus) increases bp(GO:"autophagosome assembly")
pubmed:30837838 a(CHEBI:sirolimus) increases path(MESH:Proteolysis)
pubmed:30837838 a(CHEBI:sirolimus) increases path(MESH:Memory)
pubmed:30837838 a(CHEBI:sirolimus) increases path(MESH:"Motor Activity")
pubmed:30837838 a(CHEBI:sirolimus) decreases p(HGNC:CASP3)
pubmed:30837838 a(CHEBI:sirolimus) decreases p(HGNC:TARDBP, loc(GO:cytoplasm))
pubmed:29255009 bp(CONSO:"PI3K-Akt signaling pathway") causesNoChange act(p(MGI:Fkbp1b))
pubmed:28745240 bp(CONSO:"PI3K-Akt signaling pathway") increases act(complex(GO:"NF-kappaB complex"))
pubmed:28745240 bp(CONSO:"PI3K-Akt signaling pathway") increases act(complex(GO:"NF-kappaB complex"))
pubmed:31248781 bp(CONSO:"PI3K-Akt signaling pathway") association p(HGNC:CREBBP)
pubmed:31248781 bp(CONSO:"PI3K-Akt signaling pathway") association bp(MESH:Neuroprotection)
pubmed:29255009 act(complex(a(CHEBI:sirolimus), p(MGI:Fkbp1b))) decreases bp(CONSO:"PI3K-Akt signaling pathway")
pubmed:29255009 act(complex(a(CHEBI:sirolimus), p(MGI:Fkbp1a))) decreases bp(CONSO:"PI3K-Akt signaling pathway")
pubmed:29255009 p(MGI:Fkbp1a) decreases bp(CONSO:"PI3K-Akt signaling pathway")
pubmed:30126037 act(p(MGI:Nfkb1)) increases bp(MESH:"Cell Survival")
pubmed:30126037 act(p(MGI:Nfkb1)) increases bp(GO:"inflammatory response")
pubmed:30663117 r(HGNC:BACE1, loc(GO:cytoplasm)) positiveCorrelation path(MESH:"Alzheimer Disease")
pubmed:30663117 r(HGNC:BACE1) increases path(MESH:"Alzheimer Disease")
pubmed:21329555 r(HGNC:BACE1) positiveCorrelation path(MESH:"Alzheimer Disease")
pubmed:29179999 r(HGNC:BACE1) association act(p(FPLX:NFkappaB))
pubmed:27288790 r(HGNC:BACE1) decreases p(HGNC:UCHL1)
pubmed:27288790 r(HGNC:BACE1) decreases act(p(HGNC:UCHL1))
pubmed:30663117 r(HGNC:BACE1-AS) biomarkerFor path(MESH:"Alzheimer Disease")
pubmed:30663117 r(HGNC:BACE1-AS) positiveCorrelation path(MESH:"Alzheimer Disease")
pubmed:30663117 r(HGNC:BACE1-AS) increases r(HGNC:BACE1)
pubmed:27288790 r(HGNC:BACE1-AS) regulates r(HGNC:BACE1)
pubmed:27288790 r(HGNC:BACE1-AS) decreases deg(r(HGNC:BACE1))
pubmed:30663117 r(HGNC:BACE1-AS) increases a(CHEBI:amyloid-beta)
pubmed:30663117 r(HGNC:BACE1-AS) increases path(MESH:"Plaque, Amyloid")
pubmed:27288790 r(HGNC:BACE1-AS) regulates p(HGNC:BACE1)
pubmed:27288790 r(HGNC:BACE1-AS) increases a(CHEBI:"amyloid-beta polypeptide 42")
pubmed:25652642 path(MESH:"Plaque, Amyloid") positiveCorrelation act(complex(GO:"NF-kappaB complex"))
pubmed:25652642 path(MESH:"Plaque, Amyloid") association complex(GO:"NF-kappaB complex")
pubmed:25652642 path(MESH:"Plaque, Amyloid") association a(MESH:"HLA-DR Antigens")
pubmed:29196815 path(MESH:"Plaque, Amyloid") positiveCorrelation path(MESH:"Alzheimer Disease")
pubmed:19126755 path(MESH:"Plaque, Amyloid") positiveCorrelation path(MESH:"Alzheimer Disease")
pubmed:19293145 path(MESH:"Plaque, Amyloid") positiveCorrelation path(MESH:"Alzheimer Disease")
pubmed:19293145 path(MESH:"Plaque, Amyloid") biomarkerFor path(MESH:"Alzheimer Disease")
pubmed:19293145 path(MESH:"Plaque, Amyloid") association path(MESH:"Alzheimer Disease")
pubmed:24511233 path(MESH:"Plaque, Amyloid") biomarkerFor path(MESH:"Alzheimer Disease")
pubmed:24590577 path(MESH:"Plaque, Amyloid") association path(MESH:"Alzheimer Disease")
pubmed:25514383 path(MESH:"Plaque, Amyloid") positiveCorrelation path(MESH:"Alzheimer Disease")
pubmed:29758300 path(MESH:"Plaque, Amyloid") positiveCorrelation path(MESH:"Alzheimer Disease")
pubmed:22817713 path(MESH:"Plaque, Amyloid") positiveCorrelation path(MESH:"Alzheimer Disease")
pubmed:21871088 path(MESH:"Plaque, Amyloid") increases bp(GO:"microglial cell activation")
pubmed:19293145 path(MESH:"Plaque, Amyloid") association p(HGNC:CHRNA7)
pubmed:19293145 path(MESH:"Plaque, Amyloid") causesNoChange r(HGNC:CHRNA4)
pubmed:19293145 path(MESH:"Plaque, Amyloid") causesNoChange r(HGNC:CHRNA7)
pubmed:24511233 path(MESH:"Plaque, Amyloid") association a(CONSO:"amyloid-beta aggregates")
pubmed:26195256 path(MESH:"Plaque, Amyloid") association a(CONSO:"amyloid-beta aggregates")
pubmed:24511233 path(MESH:"Plaque, Amyloid") increases path(CONSO:neuroinflammation)
pubmed:24511233 path(MESH:"Plaque, Amyloid") increases bp(GO:"cell death")
pubmed:24590577 path(MESH:"Plaque, Amyloid") association bp(GO:"synaptic transmission, cholinergic")
pubmed:25514383 path(MESH:"Plaque, Amyloid") association complex(a(CHEBI:"amyloid-beta polypeptide 42"), p(HGNC:CHRNA7))
pubmed:18986241 path(MESH:"Plaque, Amyloid") association p(HGNC:BCHE)
pubmed:18986241 path(MESH:"Plaque, Amyloid") association p(HGNC:ACHE)
pubmed:26010758 path(MESH:"Plaque, Amyloid") association p(FPLX:NFkappaB, pmod(go:0006468 ! "protein phosphorylation", Ser, 536))
pubmed:27299292 path(MESH:"Plaque, Amyloid") negativeCorrelation p(HGNC:TFEB)
pubmed:14556719 path(MESH:"Plaque, Amyloid") association a(MESH:"Amyloid beta-Peptides")
pubmed:24027553 path(MESH:"Plaque, Amyloid") association p(HGNC:MAP1LC3A)
pubmed:28420982 path(MESH:"Plaque, Amyloid") association a(MESH:Exosomes)
pubmed:26195256 path(MESH:"Plaque, Amyloid") negativeCorrelation act(p(HGNC:MMP2))
pubmed:26195256 path(MESH:"Plaque, Amyloid") increases act(a(MESH:Astrocytes))
pubmed:18562203 path(MESH:"Plaque, Amyloid") association act(a(MESH:Astrocytes))
pubmed:23531502 path(MESH:"Plaque, Amyloid") association act(a(CHEBI:acrolein))
pubmed:18562203 path(MESH:"Plaque, Amyloid") positiveCorrelation p(HGNC:MAPT, pmod(CONSO:nitration, Tyr, 18))
pubmed:26400044 path(MESH:"Plaque, Amyloid") association complex(p(MGI:Dpysl2, pmod(go:0006468 ! "protein phosphorylation")), p(MGI:Mapt, pmod(go:0006468 ! "protein phosphorylation")), p(MGI:Wasf1, pmod(go:0006468 ! "protein phosphorylation")))
pubmed:23088643 path(MESH:"Plaque, Amyloid") association p(CONSO:"Tau epitope, AT8")
pubmed:28877763 path(MESH:"Plaque, Amyloid") association a(CONSO:"dystrophic neurite")
pubmed:24401760 path(MESH:"Plaque, Amyloid") association a(CONSO:"dystrophic neurite")
pubmed:28877763 path(MESH:"Plaque, Amyloid") positiveCorrelation p(HGNC:SYK, pmod(go:0006468 ! "protein phosphorylation"))
pubmed:24401760 path(MESH:"Plaque, Amyloid") positiveCorrelation p(HGNC:ITPKB)
pubmed:30988501 path(MESH:"Plaque, Amyloid") association a(MESH:"Herpesvirus 1, Human")
pubmed:30663117 g(HGNC:MIR124-1) decreases p(HGNC:BACE1)
pubmed:10656250 p(HGNC:BACE1) increases tloc(p(CONSO:sAPP-beta), fromLoc(go:0005622 ! intracellular), toLoc(go:0005615 ! "extracellular space"))
pubmed:24590577 p(HGNC:BACE1) increases p(CONSO:sAPP-beta)
pubmed:10656250 p(HGNC:BACE1) causesNoChange tloc(p(CONSO:sAPP-alpha), fromLoc(go:0005622 ! intracellular), toLoc(go:0005615 ! "extracellular space"))
pubmed:10656250 p(HGNC:BACE1) causesNoChange p(HGNC:APP)
pubmed:10656250 p(HGNC:BACE1, loc(GO:"endoplasmic reticulum")) association p(HGNC:APP, loc(GO:"endoplasmic reticulum"))
pubmed:24590577 p(HGNC:BACE1) increases deg(p(HGNC:APP))
pubmed:21718217 p(HGNC:BACE1) decreases p(HGNC:APP)
pubmed:10656250 p(HGNC:BACE1) increases p(HGNC:APP, frag("672_770"))
pubmed:10656250 p(HGNC:BACE1) association p(CONSO:APP695)
pubmed:10656250 p(HGNC:BACE1) association p(CONSO:APP751)
pubmed:30444369 p(HGNC:BACE1) increases rxn(reactants(p(HGNC:APP)), products(a(CHEBI:"amyloid-beta polypeptide 42"), p(CONSO:"APP C-terminally truncated carboxyl-terminal fragments")))
pubmed:18650430 act(p(HGNC:BACE1), ma(go:0008233 ! "peptidase activity")) increases rxn(reactants(p(HGNC:APP)), products(p(HGNC:APP, frag("11_*")), p(HGNC:APP, frag("1_10"))))
pubmed:21214928 p(HGNC:BACE1) increases rxn(reactants(p(HGNC:APP)), products(a(CHEBI:amyloid-beta)))
pubmed:21214928 p(HGNC:BACE1) increases rxn(reactants(p(HGNC:APP)), products(a(CHEBI:amyloid-beta)))
pubmed:21214928 p(HGNC:BACE1) increases rxn(reactants(p(HGNC:APP)), products(a(CHEBI:amyloid-beta)))
pubmed:22122372 p(HGNC:BACE1) increases rxn(reactants(p(HGNC:APP)), products(a(CHEBI:amyloid-beta)))
pubmed:21722302 p(HGNC:BACE1) increases rxn(reactants(p(HGNC:APP)), products(a(CHEBI:amyloid-beta)))
pubmed:21214928 p(HGNC:BACE1) increases bp(GO:"neuron death")
pubmed:21214928 p(HGNC:BACE1) decreases bp(GO:"synaptic transmission, cholinergic")
pubmed:21214928 p(HGNC:BACE1) decreases bp(GO:memory)
pubmed:21214928 p(HGNC:BACE1) increases p(HGNC:APP, frag("672_713"))
pubmed:21214928 p(HGNC:BACE1) increases p(HGNC:APP, frag("672_711"))
pubmed:22122372 p(HGNC:BACE1) increases rxn(reactants(p(HGNC:APP)), products(p(CONSO:CONSO00042), p(CONSO:CONSO00081)))
pubmed:22122372 p(HGNC:BACE1) increases rxn(reactants(p(HGNC:APP)), products(p(CONSO:CONSO00042), p(CONSO:CONSO00081)))
pubmed:22122372 p(HGNC:BACE1) increases a(CHEBI:amyloid-beta)
pubmed:18986241 act(p(HGNC:BACE1)) increases a(CHEBI:amyloid-beta)
pubmed:25331948 p(HGNC:BACE1) increases a(CHEBI:amyloid-beta)
pubmed:26195256 act(p(HGNC:BACE1)) increases a(CHEBI:amyloid-beta)
pubmed:29626319 p(HGNC:BACE1) increases a(CHEBI:amyloid-beta)
pubmed:19126755 p(HGNC:BACE1) increases a(CHEBI:"amyloid-beta polypeptide 42")
pubmed:24590577 p(HGNC:BACE1) increases p(CONSO:C99)
pubmed:21718217 p(HGNC:BACE1) increases a(CHEBI:"amyloid-beta polypeptide 40")
pubmed:23516100 p(HGNC:BACE1) association act(p(HGNCGENEFAMILY:Calpains))
pubmed:23516100 act(p(HGNC:BACE1)) increases p(HGNC:APP, frag("?"))
pubmed:23516100 act(p(HGNC:BACE1)) increases p(HGNC:APP, frag("?"), loc(GO:"secretory vesicle"))
pubmed:29758300 p(HGNC:BACE1) increases p(HGNC:APP, frag("?"))
pubmed:14556719 p(HGNC:BACE1) increases rxn(reactants(p(HGNC:APP)), products(a(CHEBI:"amyloid-beta polypeptide 40"), a(CHEBI:"amyloid-beta polypeptide 42")))
pubmed:30663117 complex(g(HGNC:MIR124-1), r(HGNC:BACE1)) decreases act(r(HGNC:BACE1))
pubmed:30663117 complex(g(HGNC:MIR15B), r(HGNC:BACE1)) decreases p(HGNC:BACE1)
pubmed:30663117 complex(g(HGNC:MIR339), r(HGNC:BACE1)) decreases p(HGNC:BACE1)
pubmed:30663117 complex(g(HGNC:MIR384), r(HGNC:BACE1)) decreases p(HGNC:BACE1)
pubmed:30663117 g(HGNC:MIR384) association path(MESH:"Alzheimer Disease")
pubmed:30663117 complex(g(HGNC:MIR384), r(HGNC:APP)) decreases p(HGNC:APP)
pubmed:24107444 p(HGNC:APP) association complex(GO:"gamma-secretase complex")
pubmed:24883238 p(HGNC:APP) association p(HGNC:STK11)
pubmed:24883238 p(HGNC:APP) increases p(HGNC:MAPT, pmod(go:0006468 ! "protein phosphorylation"))
pubmed:17234589 p(HGNC:APP) association p(FB:Lkb1)
pubmed:31346362 p(HGNC:APP) increases path(DOID:"Alzheimer's disease")
pubmed:30232325 p(HGNC:APP) increases act(p(HGNC:WNT3A))
pubmed:30232325 p(HGNC:APP) increases act(p(HGNC:WNT5A))
pubmed:30232325 p(HGNC:APP) increases bp(GO:"canonical Wnt signaling pathway")
pubmed:30232325 p(HGNC:APP) increases bp(GO:"non-canonical Wnt signaling pathway")
pubmed:11230871 act(p(HGNC:APP)) association p(HGNC:APP, var("p.Lys670Asn"), var("p.Met671Leu"))
pubmed:30232325 p(HGNC:APP) increases act(p(HGNC:DKK1))
pubmed:30232325 p(HGNC:APP) increases act(p(HGNC:DKK1))
pubmed:30232325 p(HGNC:APP) increases path(CONSO:CONSO00061)
pubmed:10656250 p(HGNC:APP, loc(GO:"endoplasmic reticulum")) association p(HGNC:BACE1, loc(GO:"endoplasmic reticulum"))
pubmed:21034527 p(HGNC:APP) regulates p(HGNC:BACE1)
pubmed:21034527 act(p(HGNC:APP), ma(go:0001071 ! "nucleic acid binding transcription factor activity")) increases act(p(HGNC:BACE1))
pubmed:18650430 p(HGNC:APP) increases bp(GO:"regulation of cell growth")
pubmed:18650430 p(HGNC:APP) increases bp(GO:"synapse assembly")
pubmed:21214928 p(HGNC:APP) association bp(GO:"synapse assembly")
pubmed:18650430 p(HGNC:APP) increases bp(MESH:"Neuronal Outgrowth")
pubmed:21214928 p(HGNC:APP) association bp(MESH:"Neuronal Outgrowth")
pubmed:18650430 p(HGNC:APP) increases bp(GO:"cell adhesion")
pubmed:21214928 p(HGNC:APP) association bp(GO:"cell adhesion")
pubmed:22122372 p(HGNC:APP) increases bp(GO:"cell adhesion")
pubmed:18650430 p(HGNC:APP) regulates act(p(HGNC:SLC5A7))
pubmed:21214928 p(HGNC:APP) increases a(CHEBI:amyloid-beta)
pubmed:22122372 p(HGNC:APP) increases a(CHEBI:amyloid-beta)
pubmed:26027813 p(HGNC:APP) increases a(CHEBI:amyloid-beta)
pubmed:21722302 p(HGNC:APP) increases a(CHEBI:amyloid-beta)
pubmed:18930136 deg(p(HGNC:APP)) association a(CHEBI:amyloid-beta)
pubmed:21214928 p(HGNC:APP) association bp(GO:"signal transduction")
pubmed:21214928 p(HGNC:APP) association bp(GO:"calcium ion homeostasis")
pubmed:21214928 p(HGNC:APP) association bp(GO:"protein transport")
pubmed:21214928 p(HGNC:APP) regulates bp(GO:"protein transport")
pubmed:21214928 p(HGNC:APP) association p(HGNC:ITGB1)
pubmed:21214928 p(HGNC:APP) association bp(GO:"anterograde axonal protein transport")
pubmed:21156028 deg(p(HGNC:APP)) increases p(HGNC:APP, frag("672_713"))
pubmed:26996954 p(HGNC:APP) decreases p(HGNC:APP, frag("672_713"))
pubmed:21156028 deg(p(HGNC:APP)) increases p(HGNC:APP, frag("672_711"))
pubmed:22122372 p(HGNC:APP) increases a(MESH:"Amyloid beta-Peptides")
pubmed:29758300 p(HGNC:APP) increases a(MESH:"Amyloid beta-Peptides")
pubmed:14556719 p(HGNC:APP) increases a(MESH:"Amyloid beta-Peptides")
pubmed:22122372 p(HGNC:APP) association p(CONSO:CONSO00078)
pubmed:22122372 p(HGNC:APP) association p(CONSO:CONSO00079)
pubmed:22122372 p(HGNC:APP) association a(MESH:"Receptors, Cell Surface")
pubmed:21034527 p(HGNC:APP) regulates p(HGNC:APP)
pubmed:21034527 act(p(HGNC:APP), ma(go:0001071 ! "nucleic acid binding transcription factor activity")) increases act(p(HGNC:APP))
pubmed:21034527 p(HGNC:APP) regulates p(HGNC:KAT5)
pubmed:21034527 act(p(HGNC:APP), ma(go:0001071 ! "nucleic acid binding transcription factor activity")) increases act(p(HGNC:KAT5))
pubmed:21034527 p(HGNC:APP) regulates p(HGNC:GSK3B)
pubmed:21034527 act(p(HGNC:APP)) increases act(p(HGNC:GSK3B))
pubmed:26968346 deg(p(HGNC:APP)) decreases p(HGNC:GSK3B)
pubmed:21034527 p(HGNC:APP) regulates p(HGNC:TP53)
pubmed:21034527 act(p(HGNC:APP), ma(go:0001071 ! "nucleic acid binding transcription factor activity")) increases act(p(HGNC:TP53))
pubmed:21034527 p(HGNC:APP) regulates p(HGNC:SOD2)
pubmed:21034527 act(p(HGNC:APP), ma(go:0001071 ! "nucleic acid binding transcription factor activity")) increases act(p(HGNC:SOD2))
pubmed:21034527 p(HGNC:APP) regulates p(HGNC:CD82)
pubmed:21034527 act(p(HGNC:APP), ma(go:0001071 ! "nucleic acid binding transcription factor activity")) increases act(p(HGNC:CD82))
pubmed:21034527 p(HGNC:APP) regulates p(HGNC:MME)
pubmed:21034527 p(HGNC:APP) regulates p(HGNC:TAGLN)
pubmed:21034527 act(p(HGNC:APP), ma(go:0001071 ! "nucleic acid binding transcription factor activity")) increases act(p(HGNC:TAGLN))
pubmed:21034527 p(HGNC:APP) regulates p(HGNC:ACTA2)
pubmed:21034527 act(p(HGNC:APP), ma(go:0001071 ! "nucleic acid binding transcription factor activity")) increases act(p(HGNC:ACTA2))
pubmed:21034527 p(HGNC:APP) regulates p(HGNC:S100A9)
pubmed:21034527 act(p(HGNC:APP), ma(go:0001071 ! "nucleic acid binding transcription factor activity")) increases act(p(HGNC:S100A9))
pubmed:22110360 p(HGNC:APP) association p(HGNC:DYRK1A)
pubmed:21034527 act(p(HGNC:APP), ma(go:0001071 ! "nucleic acid binding transcription factor activity")) association p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")
pubmed:21034527 act(p(HGNC:APP), ma(go:0001071 ! "nucleic acid binding transcription factor activity")) increases act(p(HGNC:BACE2))
pubmed:21034527 act(p(HGNC:APP), ma(go:0001071 ! "nucleic acid binding transcription factor activity")) increases act(p(HGNC:MMEL1))
pubmed:19926167 deg(p(HGNC:APP)) association p(HGNC:CTSD)
pubmed:25570489 p(HGNC:APP) association a(NIFT:"Cerebral atrophy")
pubmed:20100581 p(HGNC:APP) association bp(HP:Neurodegeneration)
pubmed:25678559 p(HGNC:APP) increases a(NIFT:"Hippocampal Formation")
pubmed:25678559 p(HGNC:APP) negativeCorrelation a(NIFT:"Hippocampus volume")
pubmed:25678559 p(HGNC:APP) negativeCorrelation a(NIFT:"Mini mental state exam")