Human Brain Pharmacome Knowledge 0.0.5

Mechanistic knowledge surrounding three biological phenomena: tau modification/aggregation, nicotinic receptor signalling, and proteostasis in the context of neurodegenerative disease

Authors
Trusha Adeshara, Rana Al Disi, Daniel Domingo-Fernández, Yojana Gadiya, Charles Tapley Hoyt, Kristian Kolpeja, Sandra Spalek, Esther Wollert, Lingling Xu
Contact
charles.hoyt@scai.fraunhofer.de
License
CC BY 4.0
Copyright
Copyright © 2019 Fraunhofer SCAI, All rights reserved.

Summary

Number of Nodes
5862
Number of Edges
20860
Number of Citations
353
Number of Authors
1969
Network Density
6.07E-04
Number of Components
34
Number of Warnings
35

Nodes

Each node in a BEL graph is assigned a type. Most nodes are then identified with a namespace:identifier pair, or a definition based on other nodes as in the case of complexes, composites, and chemical reactions.

Edges

Topology

Bibliometrics

Statements

Reference BEL
pmid:30046111 tloc(a(CHEBI:"amyloid-beta"), fromLoc(MESH:Blood), toLoc(MESH:"Cerebrospinal Fluid")) regulates deg(a(CHEBI:"amyloid-beta"))
pmid:29626319 tloc(a(CHEBI:"amyloid-beta"), fromLoc(MESH:Brain), toLoc(MESH:Blood)) decreases a(CHEBI:"amyloid-beta")
pmid:30046111 a(CHEBI:"amyloid-beta") negativeCorrelation act(a(MESH:"Lymphatic Vessels"))
pmid:30046111 a(CHEBI:"amyloid-beta") positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:30046111 a(CHEBI:"amyloid-beta") positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:30046111 a(CHEBI:"amyloid-beta") positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:29196815 a(CHEBI:"amyloid-beta") positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:29196815 a(CHEBI:"amyloid-beta") positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:19293145 a(CHEBI:"amyloid-beta") increases path(MESH:"Alzheimer Disease")
pmid:19293145 sec(a(CHEBI:"amyloid-beta")) association path(MESH:"Alzheimer Disease")
pmid:19293145 a(CHEBI:"amyloid-beta") association path(MESH:"Alzheimer Disease")
pmid:25514383 a(CHEBI:"amyloid-beta") positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:11230871 a(CHEBI:"amyloid-beta") increases path(MESH:"Alzheimer Disease")
pmid:14556719 a(CHEBI:"amyloid-beta") association path(MESH:"Alzheimer Disease")
pmid:29980653 a(CHEBI:"amyloid-beta") positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:30046111 a(CHEBI:"amyloid-beta") association a(MESH:Macrophages)
pmid:28745240 a(CHEBI:"amyloid-beta") decreases bp(GO:"calcium ion homeostasis")
pmid:28745240 a(CHEBI:"amyloid-beta") association bp(MESH:"Oxidative Stress")
pmid:28745240 a(CHEBI:"amyloid-beta") increases bp(MESH:"Oxidative Stress")
pmid:28745240 a(CHEBI:"amyloid-beta") increases bp(GO:"apoptotic process")
pmid:28745240 a(CHEBI:"amyloid-beta") increases bp(GO:"apoptotic process")
pmid:19293145 act(a(CHEBI:"amyloid-beta")) increases bp(GO:"apoptotic process")
pmid:28745240 a(CHEBI:"amyloid-beta") increases bp(GO:"JNK cascade")
pmid:28745240 a(CHEBI:"amyloid-beta") increases bp(GO:"Fas signaling pathway")
pmid:28745240 a(CHEBI:"amyloid-beta") increases act(complex(GO:"NF-kappaB complex"))
pmid:28745240 a(CHEBI:"amyloid-beta") increases act(complex(GO:"NF-kappaB complex"))
pmid:28745240 a(CHEBI:"amyloid-beta") increases complex(GO:"NF-kappaB complex")
pmid:28745240 a(CHEBI:"amyloid-beta") increases act(complex(GO:"NF-kappaB complex"))
pmid:28745240 a(CHEBI:"amyloid-beta") increases act(complex(GO:"NF-kappaB complex"))
pmid:25652642 a(CHEBI:"amyloid-beta") increases act(complex(GO:"NF-kappaB complex"))
pmid:25652642 a(CHEBI:"amyloid-beta") positiveCorrelation act(complex(GO:"NF-kappaB complex"))
pmid:25652642 a(CHEBI:"amyloid-beta") decreases act(complex(GO:"NF-kappaB complex"))
pmid:25652642 a(CHEBI:"amyloid-beta") increases act(complex(GO:"NF-kappaB complex"))
pmid:28745240 a(CHEBI:"amyloid-beta") decreases p(HGNC:BCL2L1)
pmid:25652642 a(CHEBI:"amyloid-beta") decreases p(HGNC:BCL2L1)
pmid:28745240 a(CHEBI:"amyloid-beta") decreases sec(a(PUBCHEM:16057918))
pmid:28745240 a(CHEBI:"amyloid-beta") increases complex(a(GO:"membrane attack complex"), p(HGNC:C5))
pmid:28745240 a(CHEBI:"amyloid-beta") increases p(HGNC:TNF)
pmid:29179999 a(CHEBI:"amyloid-beta") increases sec(p(HGNC:TNF))
pmid:28019679 a(CHEBI:"amyloid-beta") increases sec(p(HGNC:TNF))
pmid:28745240 a(CHEBI:"amyloid-beta") increases p(HGNC:APP)
pmid:18930136 a(CHEBI:"amyloid-beta") association deg(p(HGNC:APP))
pmid:28745240 a(CHEBI:"amyloid-beta") increases act(complex(GO:"calcium- and calmodulin-dependent protein kinase complex"))
pmid:28745240 a(CHEBI:"amyloid-beta") regulates act(p(FPLX:PKC))
pmid:28745240 a(CHEBI:"amyloid-beta") regulates bp(HBP:"PI3K-Akt signaling pathway")
pmid:28745240 a(CHEBI:"amyloid-beta") increases path(HBP:neurotoxicity)
pmid:25652642 a(CHEBI:"amyloid-beta") increases path(HBP:neurotoxicity)
pmid:19293145 a(CHEBI:"amyloid-beta") increases path(HBP:neurotoxicity)
pmid:19293145 act(a(CHEBI:"amyloid-beta")) increases path(HBP:neurotoxicity)
pmid:19293145 act(a(CHEBI:"amyloid-beta")) increases path(HBP:neurotoxicity)
pmid:19293145 act(a(CHEBI:"amyloid-beta")) increases path(HBP:neurotoxicity)
pmid:24590577 a(CHEBI:"amyloid-beta") increases path(HBP:neurotoxicity)
pmid:21882945 a(CHEBI:"amyloid-beta") increases path(HBP:neurotoxicity)
pmid:28745240 a(CHEBI:"amyloid-beta") increases a(CHEBI:"calcium(2+)")
pmid:28745240 a(CHEBI:"amyloid-beta") increases act(a(MESH:Microglia))
pmid:29179999 a(CHEBI:"amyloid-beta") increases bp(GO:"glial cell activation")
pmid:29179999 a(CHEBI:"amyloid-beta") increases bp(GO:"inflammatory response")
pmid:16566606 a(CHEBI:"amyloid-beta") increases bp(GO:"inflammatory response")
pmid:29179999 a(CHEBI:"amyloid-beta") increases sec(p(HGNC:IL1B))
pmid:29179999 a(CHEBI:"amyloid-beta") increases sec(p(HGNC:IL6))
pmid:29179999 a(CHEBI:"amyloid-beta") increases act(p(FPLX:NFkappaB))
pmid:27288790 a(CHEBI:"amyloid-beta") increases act(p(FPLX:NFkappaB))
pmid:26010758 a(CHEBI:"amyloid-beta") increases act(p(FPLX:NFkappaB))
pmid:27288790 a(CHEBI:"amyloid-beta") increases act(p(HGNC:NFKB1))
pmid:27288790 a(CHEBI:"amyloid-beta") increases act(p(HGNC:RELA))
pmid:25652642 a(CHEBI:"amyloid-beta") increases act(p(HGNC:APOE))
pmid:26195256 tloc(a(CHEBI:"amyloid-beta"), fromLoc(MESH:"Extracellular Space"), toLoc(MESH:"Cardiovascular System")) negativeCorrelation tloc(p(HGNC:APOE), fromLoc(MESH:"Extracellular Space"), toLoc(MESH:"Cardiovascular System"))
pmid:25652642 a(CHEBI:"amyloid-beta") increases bp(GO:"neuron death")
pmid:21214928 a(CHEBI:"amyloid-beta") increases bp(GO:"neuron death")
pmid:22122372 a(CHEBI:"amyloid-beta") increases bp(GO:"neuron death")
pmid:22122372 a(CHEBI:"amyloid-beta") increases bp(GO:"neuron death")
pmid:25652642 a(CHEBI:"amyloid-beta") increases p(HGNC:BAX)
pmid:19293145 a(CHEBI:"amyloid-beta") increases p(HGNC:BAX)
pmid:19293145 a(CHEBI:"amyloid-beta") increases act(p(HGNC:BAX))
pmid:25652642 a(CHEBI:"amyloid-beta") increases a(MESH:"I-kappa B Proteins")
pmid:30232325 a(CHEBI:"amyloid-beta") increases bp(HBP:HBP00061)
pmid:21214928 a(CHEBI:"amyloid-beta") increases bp(HBP:HBP00061)
pmid:22122372 a(CHEBI:"amyloid-beta") increases bp(HBP:HBP00061)
pmid:22122372 a(CHEBI:"amyloid-beta") increases bp(HBP:HBP00061)
pmid:29196815 a(CHEBI:"amyloid-beta") increases bp(GO:"neuron apoptotic process")
pmid:29196815 a(CHEBI:"amyloid-beta") increases complex(GO:"neurofibrillary tangle")
pmid:29196815 a(CHEBI:"amyloid-beta") increases path(MESH:Gliosis)
pmid:29196815 a(CHEBI:"amyloid-beta") increases path(MESH:"Neuroaxonal Dystrophies")
pmid:18650430 a(CHEBI:"amyloid-beta") increases bp(GO:"cell adhesion")
pmid:21214928 a(CHEBI:"amyloid-beta") increases path(MESH:"Plaque, Amyloid")
pmid:21214928 a(CHEBI:"amyloid-beta") increases path(MESH:"Plaque, Amyloid")
pmid:21214928 a(CHEBI:"amyloid-beta") increases bp(HBP:HBP00027)
pmid:21214928 a(CHEBI:"amyloid-beta") decreases bp(GO:"regulation of synapse structure or activity")
pmid:21214928 a(CHEBI:"amyloid-beta") decreases bp(GO:"regulation of synapse structure or activity")
pmid:22122372 a(CHEBI:"amyloid-beta") decreases bp(GO:"regulation of synapse structure or activity")
pmid:22122372 a(CHEBI:"amyloid-beta") decreases bp(GO:"regulation of synapse structure or activity")
pmid:21214928 a(CHEBI:"amyloid-beta") increases bp(GO:"neurofibrillary tangle assembly")
pmid:22122372 a(CHEBI:"amyloid-beta") increases bp(GO:"neurofibrillary tangle assembly")
pmid:21214928 a(CHEBI:"amyloid-beta") association bp(GO:"MAPK cascade")
pmid:21214928 a(CHEBI:"amyloid-beta") association bp(GO:"ERK1 and ERK2 cascade")
pmid:21214928 a(CHEBI:"amyloid-beta") decreases a(MESH:Synapses)
pmid:19293145 a(CHEBI:"amyloid-beta") decreases a(MESH:Synapses)
pmid:21214928 a(CHEBI:"amyloid-beta") decreases bp(GO:memory)
pmid:25514383 a(CHEBI:"amyloid-beta") increases bp(GO:memory)
pmid:29758300 sec(a(CHEBI:"amyloid-beta")) increases bp(GO:memory)
pmid:22908190 a(CHEBI:"amyloid-beta") decreases bp(GO:memory)
pmid:21214928 a(CHEBI:"amyloid-beta") association bp(MESH:"Synaptic Transmission")
pmid:21214928 a(CHEBI:"amyloid-beta") decreases bp(GO:"long-term synaptic potentiation")
pmid:21214928 a(CHEBI:"amyloid-beta") association a(MESH:"Potassium Channels")
pmid:21214928 a(CHEBI:"amyloid-beta") increases bp(GO:"cell death")
pmid:21214928 a(CHEBI:"amyloid-beta") association complex(p(HGNC:APBA1), p(HGNC:APP))
pmid:21214928 sec(a(CHEBI:"amyloid-beta")) association complex(p(HGNC:APBA1), p(HGNC:APP))
pmid:21214928 a(CHEBI:"amyloid-beta") association complex(p(HGNC:APBA2), p(HGNC:APP))
pmid:21214928 sec(a(CHEBI:"amyloid-beta")) association complex(p(HGNC:APBA2), p(HGNC:APP))
pmid:21214928 a(CHEBI:"amyloid-beta") association complex(p(HGNC:APBA3), p(HGNC:APP))
pmid:21214928 sec(a(CHEBI:"amyloid-beta")) association complex(p(HGNC:APBA3), p(HGNC:APP))
pmid:21214928 a(CHEBI:"amyloid-beta") association a(CHEBI:"phorbol ester")
pmid:22122372 a(CHEBI:"amyloid-beta") decreases bp(GO:"learning or memory")
pmid:22122372 a(CHEBI:"amyloid-beta") increases a(HBP:HBP00038)
pmid:22122372 a(CHEBI:"amyloid-beta") increases a(HBP:HBP00018)
pmid:30061532 a(CHEBI:"amyloid-beta") association path(MESH:"Lewy Body Disease")
pmid:19293145 a(CHEBI:"amyloid-beta") association bp(GO:"synaptic transmission, cholinergic")
pmid:19293145 a(CHEBI:"amyloid-beta") association bp(GO:"synaptic transmission, cholinergic")
pmid:19293145 a(CHEBI:"amyloid-beta") association p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits")
pmid:19293145 a(CHEBI:"amyloid-beta") association p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits")
pmid:19293145 a(CHEBI:"amyloid-beta") association act(p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits"))
pmid:19293145 a(CHEBI:"amyloid-beta") decreases p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits")
pmid:19293145 a(CHEBI:"amyloid-beta") decreases act(p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits"))
pmid:19293145 a(CHEBI:"amyloid-beta") positiveCorrelation p(HGNC:CHRNA7)
pmid:19293145 a(CHEBI:"amyloid-beta") increases act(p(HGNC:CHRNA7))
pmid:19293145 a(CHEBI:"amyloid-beta") association p(HGNC:CHRNA7)
pmid:19293145 a(CHEBI:"amyloid-beta") decreases act(p(HGNC:CHRNA7))
pmid:19293145 a(CHEBI:"amyloid-beta") causesNoChange p(HGNC:CHRNA7)
pmid:19293145 a(CHEBI:"amyloid-beta") causesNoChange act(p(HGNC:CHRNA7))
pmid:19293145 a(CHEBI:"amyloid-beta") increases p(HGNC:CHRNA7)
pmid:17009926 a(CHEBI:"amyloid-beta") positiveCorrelation p(HGNC:CHRNA7)
pmid:19293145 a(CHEBI:"amyloid-beta") positiveCorrelation p(HGNC:CHRNA4)
pmid:19293145 a(CHEBI:"amyloid-beta") increases p(HGNC:CHRNA4)
pmid:17009926 a(CHEBI:"amyloid-beta") positiveCorrelation p(HGNC:CHRNA4)
pmid:19293145 a(CHEBI:"amyloid-beta") increases bp(GO:"intracellular receptor signaling pathway")
pmid:19293145 act(a(CHEBI:"amyloid-beta")) association p(HGNC:FYN)
pmid:19293145 a(CHEBI:"amyloid-beta") increases act(p(HGNC:FYN))
pmid:19293145 a(CHEBI:"amyloid-beta") increases act(p(FPLX:PI3K))
pmid:19293145 a(CHEBI:"amyloid-beta") increases p(HGNC:MAPT, pmod(Ph, Tyr))
pmid:19293145 act(a(CHEBI:"amyloid-beta")) association bp(GO:"calcium-mediated signaling")
pmid:19293145 a(CHEBI:"amyloid-beta") increases act(p(HGNC:MAPK8))
pmid:19293145 a(CHEBI:"amyloid-beta") increases act(p(HGNC:MAPK14))
pmid:19293145 a(CHEBI:"amyloid-beta") causesNoChange path(HBP:Neurodegeneration)
pmid:29758300 sec(a(CHEBI:"amyloid-beta")) decreases path(HBP:Neurodegeneration)
pmid:19293145 a(CHEBI:"amyloid-beta") decreases bp(MESH:"Neuronal Outgrowth")
pmid:19293145 a(CHEBI:"amyloid-beta") decreases act(a(CHEBI:carbachol), ma(MESH:Hydrolysis))
pmid:19293145 a(CHEBI:"amyloid-beta") increases p(HGNC:MAPK1, pmod(Ph))
pmid:19293145 a(CHEBI:"amyloid-beta") decreases p(HGNC:BCL2)
pmid:19293145 a(CHEBI:"amyloid-beta") decreases act(p(HGNC:BCL2))
pmid:19293145 a(CHEBI:"amyloid-beta") increases p(HGNC:MAPT, pmod(Ph))
pmid:26813123 a(CHEBI:"amyloid-beta") regulates p(HGNC:MAPT, pmod(Ph))
pmid:19293145 a(CHEBI:"amyloid-beta") increases act(p(FPLX:JNK))
pmid:19293145 a(CHEBI:"amyloid-beta") increases act(p(FPLX:ERK))
pmid:19293145 a(CHEBI:"amyloid-beta") increases act(p(HGNC:BAD))
pmid:19293145 a(CHEBI:"amyloid-beta") association bp(GO:"choline transport")
pmid:19293145 a(CHEBI:"amyloid-beta") increases act(p(HGNC:CHRNA7, var("p.L250T")))
pmid:19293145 a(CHEBI:"amyloid-beta") increases act(complex(p(HGNC:CHRNA4), p(HGNC:CHRNB2)))
pmid:19293145 a(CHEBI:"amyloid-beta") decreases act(complex(p(HGNC:CHRNA4), p(HGNC:CHRNB2)))
pmid:19293145 a(CHEBI:"amyloid-beta") decreases act(complex(p(HGNC:CHRNA4), p(HGNC:CHRNB2)))
pmid:19293145 a(CHEBI:"amyloid-beta") causesNoChange act(complex(p(HGNC:CHRNA3), p(HGNC:CHRNB4)))
pmid:19293145 a(CHEBI:"amyloid-beta") decreases act(complex(p(HGNC:CHRNA2), p(HGNC:CHRNB2)))
pmid:19293145 a(CHEBI:"amyloid-beta") decreases act(complex(p(HGNC:CHRNA4), p(HGNC:CHRNA5), p(HGNC:CHRNB2)))
pmid:19293145 a(CHEBI:"amyloid-beta") decreases act(p(HGNC:CHRNA7, var("?")))
pmid:19293145 a(CHEBI:"amyloid-beta") decreases act(a(CHEBI:nicotine))
pmid:19293145 a(CHEBI:"amyloid-beta") increases p(HGNC:CHRNA3)
pmid:19293145 a(CHEBI:"amyloid-beta") decreases p(RGD:Chrna4)
pmid:19293145 a(CHEBI:"amyloid-beta") decreases p(RGD:Chrna7)
pmid:19293145 a(CHEBI:"amyloid-beta") increases r(RGD:Chrna7)
pmid:19293145 a(CHEBI:"amyloid-beta") increases p(MGI:Chat)
pmid:19293145 a(CHEBI:"amyloid-beta") increases r(MGI:Chrna3)
pmid:17009926 a(CHEBI:"amyloid-beta") decreases a(CHEBI:acetylcholine)
pmid:17009926 a(CHEBI:"amyloid-beta") decreases sec(a(CHEBI:acetylcholine))
pmid:25514383 a(CHEBI:"amyloid-beta") increases act(a(CHEBI:acetylcholine))
pmid:17009926 a(CHEBI:"amyloid-beta") decreases act(p(FPLX:CHRM))
pmid:26813123 a(CHEBI:"amyloid-beta") increases a(HBP:"amyloid-beta fibrils")
pmid:26813123 act(a(CHEBI:"amyloid-beta")) association act(p(HGNC:CHRM1))
pmid:24590577 a(CHEBI:"amyloid-beta") decreases act(p(HGNC:CHRM1))
pmid:24590577 a(CHEBI:"amyloid-beta") decreases complex(p(FPLX:"G_protein"), p(HGNC:CHRM1))
pmid:25514383 a(CHEBI:"amyloid-beta") increases act(a(HBP:"beta-2-containing nAChR"))
pmid:25514383 act(a(CHEBI:"amyloid-beta")) negativeCorrelation a(HBP:"alpha-7 beta-2 nAChR")
pmid:25514383 a(CHEBI:"amyloid-beta") regulates act(p(FPLX:CHRN))
pmid:25514383 a(CHEBI:"amyloid-beta") decreases act(p(FPLX:CHRN))
pmid:25514383 a(CHEBI:"amyloid-beta") increases act(a(MESH:"alpha7 Nicotinic Acetylcholine Receptor"))
pmid:25514383 a(CHEBI:"amyloid-beta") decreases act(a(MESH:"alpha7 Nicotinic Acetylcholine Receptor"))
pmid:25514383 a(CHEBI:"amyloid-beta") decreases bp(GO:"neuron cellular homeostasis")
pmid:25514383 a(CHEBI:"amyloid-beta") decreases a(GO:synapse)
pmid:22908190 a(CHEBI:"amyloid-beta") decreases act(a(GO:synapse))
pmid:26010758 a(CHEBI:"amyloid-beta") increases bp(GO:locomotion)
pmid:26010758 a(CHEBI:"amyloid-beta") decreases path(MESH:Anxiety)
pmid:26010758 a(CHEBI:"amyloid-beta") decreases path(MESH:"Interpersonal Relations")
pmid:26010758 a(CHEBI:"amyloid-beta") increases p(HGNC:AIF1)
pmid:26010758 a(CHEBI:"amyloid-beta") increases p(HGNC:PTPRC)
pmid:26010758 a(CHEBI:"amyloid-beta") increases p(HGNC:STAT3, pmod(Ph))
pmid:26010758 a(CHEBI:"amyloid-beta") increases r(HGNC:BACE1)
pmid:12428809 a(CHEBI:"amyloid-beta") association bp(GO:"axonal transport")
pmid:21722302 a(CHEBI:"amyloid-beta") association p(HGNC:XBP1)
pmid:21722302 a(CHEBI:"amyloid-beta") decreases tloc(a(CHEBI:"calcium cation"), fromLoc(GO:"endoplasmic reticulum"), toLoc(GO:cytoplasm))
pmid:29758300 a(CHEBI:"amyloid-beta") positiveCorrelation act(complex(GO:"TOR complex"))
pmid:29758300 a(CHEBI:"amyloid-beta") negativeCorrelation bp(GO:macroautophagy)
pmid:29758300 a(CHEBI:"amyloid-beta") increases p(HGNC:TARDBP, pmod(Ph))
pmid:29758300 a(CHEBI:"amyloid-beta") increases p(HGNC:TARDBP)
pmid:29758300 a(CHEBI:"amyloid-beta") positiveCorrelation p(HGNC:PICALM)
pmid:29758300 a(CHEBI:"amyloid-beta") negativeCorrelation p(HGNC:SORL1)
pmid:14556719 a(CHEBI:"amyloid-beta") decreases act(complex(GO:"proteasome complex"))
pmid:22908190 a(CHEBI:"amyloid-beta") negativeCorrelation act(complex(GO:"proteasome complex"))
pmid:14556719 a(CHEBI:"amyloid-beta") decreases bp(GO:"proteasome-mediated ubiquitin-dependent protein catabolic process")
pmid:22908190 a(CHEBI:"amyloid-beta") positiveCorrelation bp(GO:endocytosis)
pmid:22908190 a(CHEBI:"amyloid-beta") positiveCorrelation bp(GO:endocytosis)
pmid:22908190 a(CHEBI:"amyloid-beta") positiveCorrelation a(CHEBI:"amyloid-beta polypeptide 42")
pmid:25784053 a(CHEBI:"amyloid-beta") decreases act(p(FPLX:Proteasome))
pmid:24027553 a(CHEBI:"amyloid-beta") increases p(HGNC:MAPT, frag("?", "17kD"))
pmid:24027553 a(CHEBI:"amyloid-beta") increases p(HGNC:MAPT, frag("?", "35kD"))
pmid:24027553 a(CHEBI:"amyloid-beta") increases p(HGNC:MAPT, frag("?", "24kD"))
pmid:24027553 a(CHEBI:"amyloid-beta") increases p(HBP:"Tau C3")
pmid:30126037 a(CHEBI:"amyloid-beta") causesNoChange p(MGI:Cdkn2a)
pmid:30985105 a(CHEBI:"amyloid-beta") negativeCorrelation p(HGNC:APP, pmod(HBP:"O-GlcNAcylation"))
pmid:30985105 a(CHEBI:"amyloid-beta") association bp(GO:cognition)
pmid:26195256 a(CHEBI:"amyloid-beta") positiveCorrelation p(HBP:"APOE e4")
pmid:26631930 a(CHEBI:"amyloid-beta") increases path(HBP:Excitotoxicity)
pmid:26631930 a(CHEBI:"amyloid-beta") increases path(HBP:Excitotoxicity)
pmid:29626319 a(CHEBI:"amyloid-beta") increases bp(GO:"response to oxidative stress")
pmid:29626319 a(CHEBI:"amyloid-beta") increases bp(HBP:"mitochondrial dysfunction")
pmid:29626319 a(CHEBI:"amyloid-beta") positiveCorrelation bp(GO:aging)
pmid:29421605 a(CHEBI:"amyloid-beta") positiveCorrelation bp(GO:aging)
pmid:29626319 a(CHEBI:"amyloid-beta") positiveCorrelation path(MESH:"Diabetes Mellitus")
pmid:29626319 a(CHEBI:"amyloid-beta") increases act(p(HGNC:MMP2))
pmid:29626319 a(CHEBI:"amyloid-beta") increases act(p(HGNC:MMP3))
pmid:29626319 a(CHEBI:"amyloid-beta") increases act(p(HGNC:MMP9))
pmid:29626319 a(CHEBI:"amyloid-beta") decreases a(MESH:"Cerebrospinal Fluid")
pmid:29626319 deg(a(CHEBI:"amyloid-beta")) association p(HGNC:AQP4)
pmid:19251756 a(CHEBI:"amyloid-beta") increases bp(GO:"response to nitrosative stress")
pmid:19251756 a(CHEBI:"amyloid-beta") positiveCorrelation complex(p(HGNC:MAPT), p(INTERPRO:"Triosephosphate isomerase", pmod(NO)))
pmid:16566606 a(CHEBI:"amyloid-beta") increases a(CHEBI:"reactive nitrogen species")
pmid:16566606 a(CHEBI:"amyloid-beta") increases a(CHEBI:"reactive oxygen species")
pmid:29221819 a(CHEBI:"amyloid-beta") positiveCorrelation p(MGI:Dyrk1a)
pmid:28877763 a(CHEBI:"amyloid-beta") increases act(p(HGNC:SYK))
pmid:28877763 a(CHEBI:"amyloid-beta") increases a(HBP:"dystrophic neurite")
pmid:26118667 a(CHEBI:"amyloid-beta", loc(MESH:"Intracellular Space")) increases act(p(FPLX:CAPN))
pmid:22156579 a(CHEBI:"amyloid-beta") increases p(RGD:Mapt, pmod(Ph, Ser, 262))
pmid:22156579 a(CHEBI:"amyloid-beta") increases p(RGD:Mapt, pmod(Ph, Ser, 356))
pmid:22156579 a(CHEBI:"amyloid-beta") increases act(p(HGNC:MARK4))
pmid:22156579 a(CHEBI:"amyloid-beta") increases p(HBP:"Tau epitope, PHF1", pmod(Ph))
pmid:25672970 a(CHEBI:"amyloid-beta") increases bp(GO:"neuroinflammatory response")
pmid:28855586 act(a(CHEBI:"amyloid-beta")) negativeCorrelation p(HGNC:MAPT, pmod(Ac, Lys, 163), pmod(Ac, Lys, 280), pmod(Ac, Lys, 281), pmod(Ac, Lys, 369))
pmid:25378699 a(CHEBI:"amyloid-beta") increases p(RGD:Mapt, pmod(HBP:hyperphosphorylation), pmod(Sumo))
pmid:28500862 a(CHEBI:"amyloid-beta") positiveCorrelation p(HBP:"Tau aggregates")
pmid:18675254 a(CHEBI:"amyloid-beta") negativeCorrelation p(HGNC:APP, pmod(Sumo, Lys, 587))
pmid:18675254 a(CHEBI:"amyloid-beta") negativeCorrelation p(HGNC:APP, pmod(Sumo, Lys, 595))
pmid:28019679 a(CHEBI:"amyloid-beta") increases bp(GO:"innate immune response")
pmid:28019679 a(CHEBI:"amyloid-beta") increases act(complex(GO:"NLRP3 inflammasome complex"))
pmid:23702978 a(CHEBI:"amyloid-beta") increases act(complex(GO:"NLRP3 inflammasome complex"))
pmid:28019679 a(CHEBI:"amyloid-beta") increases a(CHEBI:"nitric oxide")
pmid:28019679 a(CHEBI:"amyloid-beta") increases act(complex(GO:"NLRP1 inflammasome complex"))
pmid:28019679 a(CHEBI:"amyloid-beta") increases act(p(HGNC:CASP1))
pmid:23702978 a(CHEBI:"amyloid-beta") increases act(p(HGNC:NLRP3))
pmid:27314526 a(CHEBI:"amyloid-beta") association p(HGNC:NLRP3)
pmid:23702978 a(CHEBI:"amyloid-beta") increases act(p(FPLX:TLR))
pmid:24561250 a(CHEBI:"amyloid-beta") increases act(complex(GO:"inflammasome complex"))
pmid:24561250 a(CHEBI:"amyloid-beta") increases bp(GO:phagocytosis)
pmid:24561250 a(CHEBI:"amyloid-beta") decreases a(GO:lysosome)
pmid:30046111 bp(GO:phagocytosis) regulates deg(a(CHEBI:"amyloid-beta"))
pmid:29626319 bp(GO:phagocytosis) increases deg(a(CHEBI:"amyloid-beta"))
pmid:29626319 bp(GO:phagocytosis) increases deg(a(CHEBI:"amyloid-beta"))
pmid:29626319 bp(GO:phagocytosis) increases deg(a(CHEBI:"amyloid-beta"))
pmid:29626319 bp(GO:phagocytosis) association p(HGNC:TREM2)
pmid:29626319 bp(GO:phagocytosis) association p(HGNC:ABCA7)
pmid:29626319 bp(GO:phagocytosis) association p(HGNC:CD33)
pmid:29626319 bp(GO:phagocytosis) increases deg(a(CHEBI:"amyloid-beta polypeptide 42"))
pmid:29626319 bp(GO:phagocytosis) decreases p(HGNC:MAPT)
pmid:24561250 bp(GO:phagocytosis) increases act(complex(GO:"NLRP3 inflammasome complex"))
pmid:30046111 a(MESH:Microglia) regulates deg(a(CHEBI:"amyloid-beta"))
pmid:26195256 a(MESH:Microglia) decreases a(CHEBI:"amyloid-beta", loc(MESH:"Extracellular Fluid"))
pmid:26195256 act(a(MESH:Microglia)) decreases a(CHEBI:"amyloid-beta")
pmid:28745240 act(a(MESH:Microglia)) increases p(HGNC:TNF)
pmid:28745240 act(a(MESH:Microglia)) increases p(HGNC:IL1B)
pmid:28745240 act(a(MESH:Microglia)) increases p(HGNC:IL6)
pmid:28745240 act(a(MESH:Microglia)) increases p(HGNC:CXCL8)
pmid:28745240 act(a(MESH:Microglia)) increases bp(GO:"neuron death")
pmid:25652642 act(a(MESH:Microglia)) positiveCorrelation a(CHEBI:"amyloid-beta polypeptide 42")
pmid:23178521 a(MESH:Microglia) increases a(MESH:"alpha7 Nicotinic Acetylcholine Receptor")
pmid:23383175 a(MESH:Microglia) positiveCorrelation a(MESH:Astrocytes)
pmid:23383175 a(MESH:Microglia) negativeCorrelation a(GO:"myelin sheath")
pmid:29202785 act(a(MESH:Microglia)) negativeCorrelation p(HBP:"Tau isoform F (441 aa)", var("p.Ile277Pro"), var("p.Ile308Pro"), var("p.Lys280del"))
pmid:29202785 act(a(MESH:Microglia)) positiveCorrelation p(HBP:"Tau isoform F (441 aa)", var("p.Lys280del"))
pmid:28528849 a(MESH:Microglia) regulates act(p(HBP:"Tau oligomers", var("p.Lys280del")))
pmid:26195256 act(a(MESH:Microglia)) increases a(MESH:Cytokines)
pmid:29626319 a(MESH:Microglia) increases bp(GO:"immune response")
pmid:29626319 act(a(MESH:Microglia)) increases bp(GO:"cytokine production involved in inflammatory response")
pmid:29626319 act(a(MESH:Microglia)) increases bp(GO:"inflammatory response")
pmid:29626319 act(a(MESH:Microglia)) increases bp(HBP:Neurodegeneration)
pmid:29626319 act(a(MESH:Microglia)) increases bp(GO:phagocytosis)
pmid:29626319 a(MESH:Microglia) increases bp(GO:phagocytosis)
pmid:29238289 a(MESH:Microglia) increases sec(p(HGNC:MAPT))
pmid:27314526 a(MESH:Microglia) increases p(HGNC:NLRP3)
pmid:27314526 a(MESH:Microglia) increases p(HGNC:P2RX7)
pmid:27314526 a(MESH:Microglia) increases p(HGNC:TLR4)
pmid:30046111 a(MESH:Monocytes) regulates deg(a(CHEBI:"amyloid-beta"))
pmid:29626319 a(MESH:Monocytes) increases deg(a(CHEBI:"amyloid-beta"))
pmid:29626319 a(MESH:Monocytes) increases deg(a(CHEBI:"amyloid-beta"))
pmid:30046111 a(MESH:Macrophages) regulates deg(a(CHEBI:"amyloid-beta"))
pmid:30046111 a(MESH:Macrophages) association a(CHEBI:"amyloid-beta")
pmid:26195256 a(MESH:Macrophages) increases deg(a(CHEBI:"amyloid-beta"))
pmid:30046111 a(HBP:HBP00018) positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:21718217 a(HBP:HBP00018) association path(MESH:"Alzheimer Disease")
pmid:30046111 a(HBP:HBP00018) decreases bp(GO:"neuron cellular homeostasis")
pmid:30046111 a(HBP:HBP00018) increases path(MESH:"Problem Behavior")
pmid:29196815 a(HBP:HBP00018) causesNoChange bp(GO:"neuron death")
pmid:29196815 a(HBP:HBP00018) causesNoChange bp(GO:"astrocyte activation")
pmid:22122372 a(HBP:HBP00018) association a(MESH:"Amyloid beta-Peptides")
pmid:22122372 a(HBP:HBP00018) increases path(MESH:"Plaque, Amyloid")
pmid:30046111 path(MESH:"Alzheimer Disease") positiveCorrelation a(HBP:HBP00018)
pmid:21718217 path(MESH:"Alzheimer Disease") association a(HBP:HBP00018)
pmid:22040696 path(MESH:"Alzheimer Disease") increases a(HBP:HBP00018)
pmid:30046111 path(MESH:"Alzheimer Disease") association act(a(MESH:"Lymphatic Vessels"))
pmid:30046111 path(MESH:"Alzheimer Disease") positiveCorrelation a(CHEBI:"amyloid-beta")
pmid:30046111 path(MESH:"Alzheimer Disease") positiveCorrelation a(CHEBI:"amyloid-beta")
pmid:30046111 path(MESH:"Alzheimer Disease") positiveCorrelation a(CHEBI:"amyloid-beta")
pmid:29196815 path(MESH:"Alzheimer Disease") positiveCorrelation a(CHEBI:"amyloid-beta")
pmid:29196815 path(MESH:"Alzheimer Disease") positiveCorrelation a(CHEBI:"amyloid-beta")
pmid:19293145 path(MESH:"Alzheimer Disease") association sec(a(CHEBI:"amyloid-beta"))
pmid:19293145 path(MESH:"Alzheimer Disease") association a(CHEBI:"amyloid-beta")
pmid:25514383 path(MESH:"Alzheimer Disease") positiveCorrelation a(CHEBI:"amyloid-beta")
pmid:14556719 path(MESH:"Alzheimer Disease") association a(CHEBI:"amyloid-beta")
pmid:26195256 path(MESH:"Alzheimer Disease") decreases deg(a(CHEBI:"amyloid-beta"))
pmid:29626319 path(MESH:"Alzheimer Disease") decreases deg(a(CHEBI:"amyloid-beta"))
pmid:29626319 path(MESH:"Alzheimer Disease") increases a(CHEBI:"amyloid-beta")
pmid:29980653 path(MESH:"Alzheimer Disease") positiveCorrelation a(CHEBI:"amyloid-beta")
pmid:30663117 path(MESH:"Alzheimer Disease") positiveCorrelation r(HGNC:BACE1, loc(GO:cytoplasm))
pmid:30663117 path(MESH:"Alzheimer Disease") positiveCorrelation r(HGNC:"BACE1-AS")
pmid:30663117 path(MESH:"Alzheimer Disease") association g(HGNC:MIR384)
pmid:30663117 path(MESH:"Alzheimer Disease") association g(HGNC:"MIR153-1")
pmid:30663117 path(MESH:"Alzheimer Disease") association g(HGNC:"MIR101-1")
pmid:30663117 path(MESH:"Alzheimer Disease") association g(HGNC:"MIR9-1")
pmid:30663117 path(MESH:"Alzheimer Disease") decreases g(HGNC:"MIR9-1")
pmid:21329555 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:RELA)
pmid:25652642 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:RELA)
pmid:21329555 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:BACE1)
pmid:10656250 path(MESH:"Alzheimer Disease") increases p(HGNC:BACE1)
pmid:21329555 path(MESH:"Alzheimer Disease") positiveCorrelation path(MESH:Inflammation)
pmid:27288790 path(MESH:"Alzheimer Disease") positiveCorrelation path(MESH:Inflammation)
pmid:24027553 path(MESH:"Alzheimer Disease") positiveCorrelation path(MESH:Inflammation)
pmid:28745240 path(MESH:"Alzheimer Disease") association p(HGNC:IL6)
pmid:25652642 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:IL6)
pmid:28745240 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:TNF)
pmid:27288790 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:TNF)
pmid:25652642 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:TNF)
pmid:29179999 path(MESH:"Alzheimer Disease") positiveCorrelation p(FPLX:NFkappaB)
pmid:27288790 path(MESH:"Alzheimer Disease") positiveCorrelation act(p(FPLX:NFkappaB))
pmid:27288790 path(MESH:"Alzheimer Disease") negativeCorrelation bp(GO:"regulation of synaptic plasticity")
pmid:27288790 path(MESH:"Alzheimer Disease") positiveCorrelation a(CHEBI:"reactive oxygen species")
pmid:27288790 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:IL1B)
pmid:25652642 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:IL1B)
pmid:24561250 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:IL1B)
pmid:27314526 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:IL1B)
pmid:27288790 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:IL18)
pmid:24561250 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:IL18)
pmid:27314526 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:IL18)
pmid:27314526 path(MESH:"Alzheimer Disease") association p(HGNC:IL18)
pmid:27288790 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:CXCL10)
pmid:27288790 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:TGFB1)
pmid:22020111 path(MESH:"Alzheimer Disease") increases p(HGNC:TGFB1)
pmid:27288790 path(MESH:"Alzheimer Disease") positiveCorrelation bp(GO:"MAPK cascade")
pmid:27288790 path(MESH:"Alzheimer Disease") positiveCorrelation a(CHEBI:pentosidine)
pmid:27288790 path(MESH:"Alzheimer Disease") positiveCorrelation a(HBP:GLAP)
pmid:27288790 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:PTGS2)
pmid:22020111 path(MESH:"Alzheimer Disease") increases p(HGNC:PTGS2)
pmid:27288790 path(MESH:"Alzheimer Disease") positiveCorrelation m(MIRBASE:"hsa-mir-146a")
pmid:27288790 path(MESH:"Alzheimer Disease") positiveCorrelation m(MIRBASE:"hsa-mir-155")
pmid:25652642 path(MESH:"Alzheimer Disease") positiveCorrelation complex(a(GO:"NF-kappaB complex"), p(HGNC:RELA))
pmid:25652642 path(MESH:"Alzheimer Disease") positiveCorrelation act(complex(GO:"NF-kappaB complex"))
pmid:25652642 path(MESH:"Alzheimer Disease") positiveCorrelation complex(GO:"NF-kappaB complex")
pmid:25652642 path(MESH:"Alzheimer Disease") positiveCorrelation complex(GO:"NF-kappaB complex")
pmid:25652642 path(MESH:"Alzheimer Disease") positiveCorrelation a(MESH:"HLA-DR Antigens")
pmid:25652642 path(MESH:"Alzheimer Disease") positiveCorrelation m(HGNC:"MIR9-1")
pmid:25652642 path(MESH:"Alzheimer Disease") positiveCorrelation m(HGNC:MIR34A)
pmid:25652642 path(MESH:"Alzheimer Disease") positiveCorrelation m(HGNC:MIR125B1)
pmid:25652642 path(MESH:"Alzheimer Disease") positiveCorrelation m(HGNC:MIR146A)
pmid:25652642 path(MESH:"Alzheimer Disease") positiveCorrelation m(HGNC:MIR155)
pmid:25652642 path(MESH:"Alzheimer Disease") positiveCorrelation m(HGNC:MIR339)
pmid:30444369 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:HSD17B10)
pmid:30444369 path(MESH:"Alzheimer Disease") negativeCorrelation act(p(HGNC:PRDX2))
pmid:30444369 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:PRDX2)
pmid:30444369 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:CDK5)
pmid:24653673 path(MESH:"Alzheimer Disease") association p(HGNC:CDK5)
pmid:8282104 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:CDK5)
pmid:30444369 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:SH3GL2)
pmid:29196815 path(MESH:"Alzheimer Disease") isA path(MESH:"Neurodegenerative Diseases")
pmid:24511233 path(MESH:"Alzheimer Disease") isA path(MESH:"Neurodegenerative Diseases")
pmid:24590577 path(MESH:"Alzheimer Disease") isA path(MESH:"Neurodegenerative Diseases")
pmid:29980653 path(MESH:"Alzheimer Disease") isA path(MESH:"Neurodegenerative Diseases")
pmid:29196815 path(MESH:"Alzheimer Disease") decreases bp(GO:cognition)
pmid:19126755 path(MESH:"Alzheimer Disease") negativeCorrelation bp(GO:cognition)
pmid:19293145 path(MESH:"Alzheimer Disease") decreases bp(GO:cognition)
pmid:24511233 path(MESH:"Alzheimer Disease") association bp(GO:cognition)
pmid:24511233 path(MESH:"Alzheimer Disease") decreases bp(GO:cognition)
pmid:24590577 path(MESH:"Alzheimer Disease") decreases bp(GO:cognition)
pmid:11230871 path(MESH:"Alzheimer Disease") negativeCorrelation bp(GO:cognition)
pmid:19721446 path(MESH:"Alzheimer Disease") decreases bp(GO:cognition)
pmid:29196815 path(MESH:"Alzheimer Disease") increases bp(GO:"neuron apoptotic process")
pmid:29196815 path(MESH:"Alzheimer Disease") positiveCorrelation path(MESH:"Plaque, Amyloid")
pmid:19126755 path(MESH:"Alzheimer Disease") positiveCorrelation path(MESH:"Plaque, Amyloid")
pmid:19293145 path(MESH:"Alzheimer Disease") positiveCorrelation path(MESH:"Plaque, Amyloid")
pmid:19293145 path(MESH:"Alzheimer Disease") association path(MESH:"Plaque, Amyloid")
pmid:24590577 path(MESH:"Alzheimer Disease") association path(MESH:"Plaque, Amyloid")
pmid:25514383 path(MESH:"Alzheimer Disease") positiveCorrelation path(MESH:"Plaque, Amyloid")
pmid:19721446 path(MESH:"Alzheimer Disease") increases path(MESH:"Plaque, Amyloid")
pmid:14556719 path(MESH:"Alzheimer Disease") increases path(MESH:"Plaque, Amyloid")
pmid:22817713 path(MESH:"Alzheimer Disease") positiveCorrelation path(MESH:"Plaque, Amyloid")
pmid:29196815 path(MESH:"Alzheimer Disease") positiveCorrelation a(MESH:"Amyloid beta-Peptides")
pmid:22122372 path(MESH:"Alzheimer Disease") association a(MESH:"Amyloid beta-Peptides")
pmid:29196815 path(MESH:"Alzheimer Disease") positiveCorrelation a(GO:"neurofibrillary tangle")
pmid:28420982 path(MESH:"Alzheimer Disease") positiveCorrelation a(GO:"neurofibrillary tangle")
pmid:22817713 path(MESH:"Alzheimer Disease") association a(GO:"neurofibrillary tangle")
pmid:11089576 path(MESH:"Alzheimer Disease") positiveCorrelation a(GO:"neurofibrillary tangle")
pmid:29196815 path(MESH:"Alzheimer Disease") positiveCorrelation a(HBP:HBP00074)
pmid:29196815 path(MESH:"Alzheimer Disease") positiveCorrelation a(HBP:HBP00074)
pmid:29196815 path(MESH:"Alzheimer Disease") negativeCorrelation a(CHEBI:"amyloid-beta polypeptide 42")
pmid:19293145 path(MESH:"Alzheimer Disease") association a(CHEBI:"amyloid-beta polypeptide 42")
pmid:29196815 path(MESH:"Alzheimer Disease") positiveCorrelation a(HBP:HBP00076)
pmid:29196815 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:NGFR)
pmid:21214928 path(MESH:"Alzheimer Disease") positiveCorrelation r(HBP:HBP00064)
pmid:21214928 path(MESH:"Alzheimer Disease") positiveCorrelation p(HBP:HBP00065)
pmid:21214928 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:ADAM10)
pmid:21214928 path(MESH:"Alzheimer Disease") negativeCorrelation act(p(HGNC:ADAM10))
pmid:21214928 path(MESH:"Alzheimer Disease") negativeCorrelation a(HBP:HBP00067)
pmid:22122372 path(MESH:"Alzheimer Disease") association bp(GO:"neurofibrillary tangle assembly")
pmid:22122372 path(MESH:"Alzheimer Disease") association bp(GO:"neuron death")
pmid:19293145 path(MESH:"Alzheimer Disease") increases bp(GO:"neuron death")
pmid:17009926 path(MESH:"Alzheimer Disease") positiveCorrelation bp(GO:"neuron death")
pmid:17009926 path(MESH:"Alzheimer Disease") positiveCorrelation bp(GO:"neuron death")
pmid:24590577 path(MESH:"Alzheimer Disease") increases bp(GO:"neuron death")
pmid:25514383 path(MESH:"Alzheimer Disease") positiveCorrelation bp(GO:"neuron death")
pmid:22040696 path(MESH:"Alzheimer Disease") increases bp(GO:"neuron death")
pmid:28420982 path(MESH:"Alzheimer Disease") positiveCorrelation bp(GO:"neuron death")
pmid:26631930 path(MESH:"Alzheimer Disease") positiveCorrelation bp(GO:"neuron death")
pmid:22122372 path(MESH:"Alzheimer Disease") positiveCorrelation a(HBP:HBP00064)
pmid:22122372 path(MESH:"Alzheimer Disease") positiveCorrelation a(HBP:HBP00065)
pmid:30061532 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(HBP:hyperphosphorylation))
pmid:30145931 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(HBP:hyperphosphorylation))
pmid:17403556 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(HBP:hyperphosphorylation))
pmid:25374103 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(HBP:hyperphosphorylation))
pmid:26631930 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(HBP:hyperphosphorylation))
pmid:24401760 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(HBP:hyperphosphorylation))
pmid:19126755 path(MESH:"Alzheimer Disease") negativeCorrelation p(HBP:"alpha-4 beta-2 nAChR")
pmid:19126755 path(MESH:"Alzheimer Disease") negativeCorrelation p(HBP:"alpha-4 beta-2 nAChR")
pmid:19721446 path(MESH:"Alzheimer Disease") decreases p(HBP:"alpha-4 beta-2 nAChR")
pmid:19126755 path(MESH:"Alzheimer Disease") negativeCorrelation act(p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits"))
pmid:19126755 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits")
pmid:19126755 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits")
pmid:19293145 path(MESH:"Alzheimer Disease") decreases p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits")
pmid:19293145 path(MESH:"Alzheimer Disease") decreases act(p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits"))
pmid:19293145 path(MESH:"Alzheimer Disease") association act(p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits"))
pmid:19293145 path(MESH:"Alzheimer Disease") decreases p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits")
pmid:19293145 path(MESH:"Alzheimer Disease") increases p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits")
pmid:24590577 path(MESH:"Alzheimer Disease") decreases p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits")
pmid:19721446 path(MESH:"Alzheimer Disease") decreases p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits")
pmid:19126755 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:CHRNA7)
pmid:19293145 path(MESH:"Alzheimer Disease") association p(HGNC:CHRNA7)
pmid:19293145 path(MESH:"Alzheimer Disease") decreases p(HGNC:CHRNA7)
pmid:19293145 path(MESH:"Alzheimer Disease") increases p(HGNC:CHRNA7)
pmid:19293145 path(MESH:"Alzheimer Disease") decreases p(HGNC:CHRNA7)
pmid:19293145 path(MESH:"Alzheimer Disease") decreases p(HGNC:CHRNA7)
pmid:11230871 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:CHRNA7)
pmid:22040696 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:CHRNA7)
pmid:29191965 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:CHRNA7)
pmid:19126755 path(MESH:"Alzheimer Disease") positiveCorrelation path(MESH:Dementia)
pmid:19293145 path(MESH:"Alzheimer Disease") association path(MESH:Dementia)
pmid:24511233 path(MESH:"Alzheimer Disease") association path(MESH:Dementia)
pmid:25514383 path(MESH:"Alzheimer Disease") association path(MESH:Dementia)
pmid:21718217 path(MESH:"Alzheimer Disease") increases path(MESH:Dementia)
pmid:14556719 path(MESH:"Alzheimer Disease") increases path(MESH:Dementia)
pmid:19126755 path(MESH:"Alzheimer Disease") negativeCorrelation bp(GO:"synaptic transmission, cholinergic")
pmid:24511233 path(MESH:"Alzheimer Disease") decreases bp(GO:"synaptic transmission, cholinergic")
pmid:24511233 path(MESH:"Alzheimer Disease") decreases bp(GO:"synaptic transmission, cholinergic")
pmid:26813123 path(MESH:"Alzheimer Disease") association bp(GO:"synaptic transmission, cholinergic")
pmid:24590577 path(MESH:"Alzheimer Disease") decreases bp(GO:"synaptic transmission, cholinergic")
pmid:19126755 path(MESH:"Alzheimer Disease") positiveCorrelation path(MESH:"Neurofibrillary Tangles")
pmid:24590577 path(MESH:"Alzheimer Disease") association path(MESH:"Neurofibrillary Tangles")
pmid:24027553 path(MESH:"Alzheimer Disease") positiveCorrelation path(MESH:"Neurofibrillary Tangles")
pmid:19126755 path(MESH:"Alzheimer Disease") positiveCorrelation path(MESH:"Neurogenic Inflammation")
pmid:19126755 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:CHRNA4)
pmid:19293145 path(MESH:"Alzheimer Disease") decreases p(HGNC:CHRNA4)
pmid:19293145 path(MESH:"Alzheimer Disease") decreases p(HGNC:CHRNA4)
pmid:19293145 path(MESH:"Alzheimer Disease") decreases p(HGNC:CHRNA4)
pmid:11230871 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:CHRNA4)
pmid:19293145 path(MESH:"Alzheimer Disease") decreases bp(GO:memory)
pmid:24511233 path(MESH:"Alzheimer Disease") decreases bp(GO:memory)
pmid:24511233 path(MESH:"Alzheimer Disease") decreases bp(GO:memory)
pmid:22040696 path(MESH:"Alzheimer Disease") decreases bp(GO:memory)
pmid:19293145 path(MESH:"Alzheimer Disease") decreases path(MESH:"Psychomotor Performance")
pmid:19293145 path(MESH:"Alzheimer Disease") association path(MESH:Death)
pmid:19293145 path(MESH:"Alzheimer Disease") positiveCorrelation a(MESH:"Neurofibrillary Tangles")
pmid:14556719 path(MESH:"Alzheimer Disease") increases a(MESH:"Neurofibrillary Tangles")
pmid:19293145 path(MESH:"Alzheimer Disease") association a(HBP:"amyloid-beta aggregates")
pmid:25514383 path(MESH:"Alzheimer Disease") positiveCorrelation a(HBP:"amyloid-beta aggregates")
pmid:26195256 path(MESH:"Alzheimer Disease") increases a(HBP:"amyloid-beta aggregates")
pmid:22817713 path(MESH:"Alzheimer Disease") positiveCorrelation a(HBP:"amyloid-beta aggregates")
pmid:19293145 path(MESH:"Alzheimer Disease") increases p(HGNC:BCHE)
pmid:22020111 path(MESH:"Alzheimer Disease") increases p(HGNC:BCHE)
pmid:19293145 path(MESH:"Alzheimer Disease") decreases a(CHEBI:acetylcholine)
pmid:25514383 path(MESH:"Alzheimer Disease") decreases a(CHEBI:acetylcholine)
pmid:19293145 path(MESH:"Alzheimer Disease") decreases act(p(HGNC:CHAT))
pmid:19293145 path(MESH:"Alzheimer Disease") decreases act(p(HGNC:CHAT))
pmid:26813123 path(MESH:"Alzheimer Disease") decreases act(p(HGNC:CHAT))
pmid:24590577 path(MESH:"Alzheimer Disease") decreases p(HGNC:CHAT)
pmid:25514383 path(MESH:"Alzheimer Disease") decreases act(p(HGNC:CHAT))
pmid:19293145 path(MESH:"Alzheimer Disease") decreases act(a(MESH:"Cholinesterase Inhibitors"))
pmid:19293145 path(MESH:"Alzheimer Disease") association g(HGNC:CHAT)
pmid:19293145 path(MESH:"Alzheimer Disease") association g(HGNC:ACHE)
pmid:19293145 path(MESH:"Alzheimer Disease") association a(HBP:"alpha-4 beta-2 nAChR")
pmid:11230871 path(MESH:"Alzheimer Disease") decreases a(HBP:"alpha-4 beta-2 nAChR")
pmid:19293145 path(MESH:"Alzheimer Disease") increases p(HGNC:FYN)
pmid:19293145 path(MESH:"Alzheimer Disease") increases p(HGNC:FYN)
pmid:19293145 path(MESH:"Alzheimer Disease") increases complex(p(HGNC:FYN), p(HGNC:MAPT))
pmid:24653673 path(MESH:"Alzheimer Disease") positiveCorrelation complex(p(HGNC:FYN), p(HGNC:MAPT))
pmid:19293145 path(MESH:"Alzheimer Disease") association act(p(HGNC:INS))
pmid:19293145 path(MESH:"Alzheimer Disease") association bp(GO:"regulation of cytosolic calcium ion concentration")
pmid:19293145 path(MESH:"Alzheimer Disease") association p(HGNC:PSEN1)
pmid:19293145 path(MESH:"Alzheimer Disease") association bp(GO:learning)
pmid:24511233 path(MESH:"Alzheimer Disease") decreases bp(GO:learning)
pmid:24511233 path(MESH:"Alzheimer Disease") decreases bp(GO:learning)
pmid:19293145 path(MESH:"Alzheimer Disease") association path(MESH:"Cognitive Dysfunction")
pmid:24511233 path(MESH:"Alzheimer Disease") association path(MESH:"Cognitive Dysfunction")
pmid:24511233 path(MESH:"Alzheimer Disease") association path(MESH:"Cognitive Dysfunction")
pmid:26813123 path(MESH:"Alzheimer Disease") positiveCorrelation path(MESH:"Cognitive Dysfunction")
pmid:27522251 path(MESH:"Alzheimer Disease") increases path(MESH:"Cognitive Dysfunction")
pmid:19293145 path(MESH:"Alzheimer Disease") positiveCorrelation g(HGNC:APOE)
pmid:19293145 path(MESH:"Alzheimer Disease") decreases a(MESH:"Cholinergic Neurons")
pmid:19293145 path(MESH:"Alzheimer Disease") decreases a(MESH:"Cholinergic Neurons")
pmid:19293145 path(MESH:"Alzheimer Disease") decreases a(MESH:"Cholinergic Neurons")
pmid:24511233 path(MESH:"Alzheimer Disease") decreases a(MESH:"Cholinergic Neurons")
pmid:26813123 path(MESH:"Alzheimer Disease") negativeCorrelation a(MESH:"Cholinergic Neurons")
pmid:24590577 path(MESH:"Alzheimer Disease") decreases a(MESH:"Cholinergic Neurons")
pmid:24590577 path(MESH:"Alzheimer Disease") decreases a(MESH:"Cholinergic Neurons")
pmid:19293145 path(MESH:"Alzheimer Disease") decreases complex(p(HGNC:CHRNA4), p(HGNC:CHRNB2))
pmid:19293145 path(MESH:"Alzheimer Disease") decreases act(complex(p(HGNC:CHRNA4), p(HGNC:CHRNB2)))
pmid:19293145 path(MESH:"Alzheimer Disease") decreases p(HGNC:CHRNA3)
pmid:19293145 path(MESH:"Alzheimer Disease") decreases p(HGNC:CHRNA3)
pmid:19293145 path(MESH:"Alzheimer Disease") decreases p(HGNC:CHRNA3)
pmid:11230871 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:CHRNA3)
pmid:11230871 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:CHRNA3)
pmid:11230871 path(MESH:"Alzheimer Disease") causesNoChange p(HGNC:CHRNA3)
pmid:19293145 path(MESH:"Alzheimer Disease") causesNoChange r(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits")
pmid:19293145 path(MESH:"Alzheimer Disease") decreases p(HGNC:CHRNB4)
pmid:19293145 path(MESH:"Alzheimer Disease") decreases p(HGNCGENEFAMILY:"Glutamate ionotropic receptor NMDA type subunits")
pmid:19293145 path(MESH:"Alzheimer Disease") decreases p(HGNCGENEFAMILY:"Glutamate ionotropic receptor AMPA type subunits")
pmid:19293145 path(MESH:"Alzheimer Disease") decreases p(HGNC:GABRB3)
pmid:19293145 path(MESH:"Alzheimer Disease") causesNoChange p(MGI:Chrna7)
pmid:25881725 path(MESH:"Alzheimer Disease") negativeCorrelation p(MGI:Chrna7)
pmid:19293145 path(MESH:"Alzheimer Disease") causesNoChange p(MGI:Chrna4)
pmid:24511233 path(MESH:"Alzheimer Disease") association path(MESH:"Psychotic Disorders")
pmid:24511233 path(MESH:"Alzheimer Disease") association path(MESH:"Psychotic Disorders")
pmid:24511233 path(MESH:"Alzheimer Disease") association path(MESH:"Psychotic Disorders")
pmid:24511233 path(MESH:"Alzheimer Disease") increases path(MESH:Depression)
pmid:26813123 path(MESH:"Alzheimer Disease") positiveCorrelation path(MESH:Depression)
pmid:24511233 path(MESH:"Alzheimer Disease") increases path(MESH:Anxiety)
pmid:24511233 path(MESH:"Alzheimer Disease") association bp(MESH:Aging)
pmid:17009926 path(MESH:"Alzheimer Disease") association p(FPLX:CHRN)
pmid:17009926 path(MESH:"Alzheimer Disease") negativeCorrelation act(p(FPLX:CHRN))
pmid:17009926 path(MESH:"Alzheimer Disease") negativeCorrelation p(FPLX:CHRN)
pmid:17009926 path(MESH:"Alzheimer Disease") negativeCorrelation p(FPLX:CHRN)
pmid:25514383 path(MESH:"Alzheimer Disease") decreases p(FPLX:CHRN)
pmid:11230871 path(MESH:"Alzheimer Disease") association p(FPLX:CHRN)
pmid:11230871 path(MESH:"Alzheimer Disease") negativeCorrelation p(FPLX:CHRN)
pmid:17009926 path(MESH:"Alzheimer Disease") association complex(a(CHEBI:"amyloid-beta polypeptide 42"), p(HGNC:CHRNA7))
pmid:26813123 path(MESH:"Alzheimer Disease") increases deg(a(MESH:"Basal Nucleus of Meynert"))
pmid:26813123 path(MESH:"Alzheimer Disease") negativeCorrelation a(MESH:"Basal Nucleus of Meynert")
pmid:26813123 path(MESH:"Alzheimer Disease") positiveCorrelation path(MESH:Apathy)
pmid:26813123 path(MESH:"Alzheimer Disease") association p(HGNC:ACHE)
pmid:11230871 path(MESH:"Alzheimer Disease") decreases act(p(HGNC:ACHE))
pmid:11230871 path(MESH:"Alzheimer Disease") negativeCorrelation act(p(HGNC:ACHE))
pmid:11230871 path(MESH:"Alzheimer Disease") decreases act(p(HGNC:ACHE))
pmid:26813123 path(MESH:"Alzheimer Disease") negativeCorrelation a(CHEBI:rivastigmine)
pmid:26813123 path(MESH:"Alzheimer Disease") negativeCorrelation complex(p(HGNC:CHRM1), p(INTERPRO:"G-protein alpha subunit, group Q"))
pmid:24590577 path(MESH:"Alzheimer Disease") association p(HGNCGENEFAMILY:"Cholinergic receptors muscarinic")
pmid:19721446 path(MESH:"Alzheimer Disease") decreases p(HGNCGENEFAMILY:"Cholinergic receptors muscarinic")
pmid:25514383 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT)
pmid:29758300 path(MESH:"Alzheimer Disease") association p(HGNC:MAPT)
pmid:14556719 path(MESH:"Alzheimer Disease") association p(HGNC:MAPT)
pmid:24027553 path(MESH:"Alzheimer Disease") association p(HGNC:MAPT)
pmid:24027553 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT)
pmid:27574109 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT)
pmid:27574109 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT)
pmid:30126037 path(MESH:"Alzheimer Disease") association p(HGNC:MAPT)
pmid:22419736 path(MESH:"Alzheimer Disease") causesNoChange p(HGNC:MAPT)
pmid:25374103 path(MESH:"Alzheimer Disease") increases tloc(p(HGNC:MAPT), fromLoc(GO:axon), toLoc(GO:"somatodendritic compartment"))
pmid:28420982 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT)
pmid:28420982 path(MESH:"Alzheimer Disease") increases p(HGNC:MAPT)
pmid:28420982 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT)
pmid:26631930 path(MESH:"Alzheimer Disease") increases tloc(p(HGNC:MAPT), fromLoc(GO:axon), toLoc(MESH:"Dendritic Spines"))
pmid:26631930 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT)
pmid:29980653 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT)
pmid:25514383 path(MESH:"Alzheimer Disease") negativeCorrelation a(GO:synapse)
pmid:22908190 path(MESH:"Alzheimer Disease") negativeCorrelation act(a(GO:synapse))
pmid:22908190 path(MESH:"Alzheimer Disease") negativeCorrelation act(a(GO:synapse))
pmid:25514383 path(MESH:"Alzheimer Disease") negativeCorrelation a(MESH:"White Matter")
pmid:26195256 path(MESH:"Alzheimer Disease") association a(MESH:"White Matter")
pmid:25514383 path(MESH:"Alzheimer Disease") negativeCorrelation a(HP:"cholinergic neuron")
pmid:25514383 path(MESH:"Alzheimer Disease") decreases complex(a(CHEBI:acetylcholine), p(FPLX:CHRN))
pmid:25514383 path(MESH:"Alzheimer Disease") decreases complex(a(CHEBI:acetylcholine), p(FPLX:CHRM))
pmid:25514383 path(MESH:"Alzheimer Disease") decreases complex(a(CHEBI:nicotine), p(FPLX:CHRN))
pmid:11230871 path(MESH:"Alzheimer Disease") decreases complex(a(CHEBI:nicotine), p(FPLX:CHRN))
pmid:25514383 path(MESH:"Alzheimer Disease") decreases complex(a(CHEBI:nicotine), p(FPLX:CHRM))
pmid:25514383 path(MESH:"Alzheimer Disease") decreases p(FPLX:CHRM)
pmid:25514383 path(MESH:"Alzheimer Disease") positiveCorrelation complex(p(HGNC:CHRNA7), p(HGNC:FLNA))
pmid:21718217 path(MESH:"Alzheimer Disease") positiveCorrelation a(HBP:HBP00030)
pmid:21718217 path(MESH:"Alzheimer Disease") positiveCorrelation r(HGNC:ARG1)
pmid:21718217 path(MESH:"Alzheimer Disease") positiveCorrelation r(HGNC:CHI3L1)
pmid:21718217 path(MESH:"Alzheimer Disease") association p(HBP:HBP00030)
pmid:11230871 path(MESH:"Alzheimer Disease") negativeCorrelation p(HBP:"alpha-4-containing nAChR")
pmid:11230871 path(MESH:"Alzheimer Disease") causesNoChange p(HBP:"alpha-7-containing nAChR")
pmid:11230871 path(MESH:"Alzheimer Disease") negativeCorrelation p(HBP:"alpha-7-containing nAChR")
pmid:11230871 path(MESH:"Alzheimer Disease") positiveCorrelation r(HGNC:CHRNA7)
pmid:11230871 path(MESH:"Alzheimer Disease") causesNoChange r(HGNC:CHRNA3)
pmid:11230871 path(MESH:"Alzheimer Disease") causesNoChange r(HGNC:CHRNA4)
pmid:19721446 path(MESH:"Alzheimer Disease") decreases a(MESH:Neurons)
pmid:19721446 path(MESH:"Alzheimer Disease") decreases path(MESH:"Memory, Episodic")
pmid:26837465 path(MESH:"Alzheimer Disease") increases complex(p(HGNC:ESR1), p(HGNC:MAPT))
pmid:21787755 path(MESH:"Alzheimer Disease") association a(HBP:AβOs)
pmid:28901280 path(MESH:"Alzheimer Disease") association p(MESH:"Receptors, Nicotinic")
pmid:23178521 path(MESH:"Alzheimer Disease") increases p(MGI:Il6)
pmid:23178521 path(MESH:"Alzheimer Disease") increases p(MGI:Tnf)
pmid:23178521 path(MESH:"Alzheimer Disease") increases p(MGI:Stat3, pmod(Ph))
pmid:22020111 path(MESH:"Alzheimer Disease") positiveCorrelation a(HBP:"protein aggregates")
pmid:22020111 path(MESH:"Alzheimer Disease") increases p(HGNC:AGRN)
pmid:22020111 path(MESH:"Alzheimer Disease") increases p(HGNC:ANP32A)
pmid:24653673 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:ANP32A)
pmid:22299660 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:ANP32A)
pmid:22020111 path(MESH:"Alzheimer Disease") increases p(HGNC:BAX)
pmid:22020111 path(MESH:"Alzheimer Disease") increases p(HGNC:BGN)
pmid:22020111 path(MESH:"Alzheimer Disease") increases p(HGNC:BRCA1)
pmid:22020111 path(MESH:"Alzheimer Disease") increases p(HGNC:CADPS2)
pmid:22020111 path(MESH:"Alzheimer Disease") increases p(HGNC:CAPN1)
pmid:22020111 path(MESH:"Alzheimer Disease") increases p(HGNC:CCNB1)
pmid:22020111 path(MESH:"Alzheimer Disease") increases p(HGNC:CDK1)
pmid:22020111 path(MESH:"Alzheimer Disease") increases p(HGNC:CDK2)
pmid:22020111 path(MESH:"Alzheimer Disease") increases p(HGNC:CDKN2A)
pmid:22020111 path(MESH:"Alzheimer Disease") increases p(HGNC:CXCR4)
pmid:22020111 path(MESH:"Alzheimer Disease") increases p(HGNC:EIF4EBP1)
pmid:22020111 path(MESH:"Alzheimer Disease") increases p(HGNC:FOLH1)
pmid:22020111 path(MESH:"Alzheimer Disease") increases p(HGNC:HOMER1)
pmid:22020111 path(MESH:"Alzheimer Disease") increases p(HGNC:HRH1)
pmid:22020111 path(MESH:"Alzheimer Disease") increases p(HGNC:IGF2)
pmid:22020111 path(MESH:"Alzheimer Disease") increases p(HGNC:IGFBP2)
pmid:22020111 path(MESH:"Alzheimer Disease") increases p(HGNC:LDLR)
pmid:22020111 path(MESH:"Alzheimer Disease") increases p(HGNC:MAOA)
pmid:22020111 path(MESH:"Alzheimer Disease") increases p(HGNC:NEFH)
pmid:22020111 path(MESH:"Alzheimer Disease") increases p(HGNC:NPDC1)
pmid:22020111 path(MESH:"Alzheimer Disease") increases p(HGNC:NRGN)
pmid:22020111 path(MESH:"Alzheimer Disease") increases p(HGNC:PREP)
pmid:22020111 path(MESH:"Alzheimer Disease") increases p(HGNC:PROS1)
pmid:22020111 path(MESH:"Alzheimer Disease") increases p(HGNC:PTGS1)
pmid:22020111 path(MESH:"Alzheimer Disease") increases p(HGNC:SELENBP1)
pmid:22020111 path(MESH:"Alzheimer Disease") increases p(HGNC:TAGLN)
pmid:22020111 path(MESH:"Alzheimer Disease") increases p(HGNC:TUBB3)
pmid:22020111 path(MESH:"Alzheimer Disease") increases p(HGNC:VKORC1)
pmid:22020111 path(MESH:"Alzheimer Disease") decreases p(HGNC:CANX)
pmid:22020111 path(MESH:"Alzheimer Disease") decreases p(HGNC:GCNT2)
pmid:22020111 path(MESH:"Alzheimer Disease") decreases p(HGNC:IDE)
pmid:30116051 path(MESH:"Alzheimer Disease") decreases p(HGNC:IDE)
pmid:22020111 path(MESH:"Alzheimer Disease") decreases p(HGNC:MMP1)
pmid:22020111 path(MESH:"Alzheimer Disease") decreases p(HGNC:NFE2L2)
pmid:22020111 path(MESH:"Alzheimer Disease") decreases p(HGNC:NR3C1)
pmid:22020111 path(MESH:"Alzheimer Disease") decreases p(HGNC:PPARA)
pmid:22020111 path(MESH:"Alzheimer Disease") decreases p(HGNC:SLC6A6)
pmid:22020111 path(MESH:"Alzheimer Disease") decreases p(HGNC:SYVN1)
pmid:22020111 path(MESH:"Alzheimer Disease") decreases p(HGNC:TSHZ1)
pmid:22020111 path(MESH:"Alzheimer Disease") decreases p(HGNC:TXN)
pmid:22020111 path(MESH:"Alzheimer Disease") decreases p(HGNC:ACLY)
pmid:22020111 path(MESH:"Alzheimer Disease") decreases p(HGNC:ATAD2)
pmid:22020111 path(MESH:"Alzheimer Disease") decreases p(HGNC:BECN1)
pmid:29758300 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:BECN1)
pmid:29758300 path(MESH:"Alzheimer Disease") decreases p(HGNC:BECN1)
pmid:22020111 path(MESH:"Alzheimer Disease") decreases p(HGNC:DHCR24)
pmid:22020111 path(MESH:"Alzheimer Disease") decreases p(HGNC:FGF2)
pmid:22020111 path(MESH:"Alzheimer Disease") decreases p(HGNC:HTRA1)
pmid:24027553 path(MESH:"Alzheimer Disease") association p(HGNC:HTRA1)
pmid:22020111 path(MESH:"Alzheimer Disease") decreases p(HGNC:PRKCE)
pmid:22020111 path(MESH:"Alzheimer Disease") decreases p(HGNC:PRKDC)
pmid:22020111 path(MESH:"Alzheimer Disease") decreases p(HGNC:SCD)
pmid:22020111 path(MESH:"Alzheimer Disease") decreases p(HGNC:TUBB)
pmid:22020111 path(MESH:"Alzheimer Disease") decreases p(HGNC:UNG)
pmid:22020111 path(MESH:"Alzheimer Disease") increases p(HGNC:ATP1A1)
pmid:22020111 path(MESH:"Alzheimer Disease") increases p(HGNC:CTSD)
pmid:22020111 path(MESH:"Alzheimer Disease") increases p(HGNC:GLRX)
pmid:22020111 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:GLRX)
pmid:22020111 path(MESH:"Alzheimer Disease") increases p(HGNC:HMOX1)
pmid:22020111 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:HMOX1)
pmid:22020111 path(MESH:"Alzheimer Disease") increases p(HGNC:IL6R)
pmid:22020111 path(MESH:"Alzheimer Disease") increases p(HGNC:NPTX1)
pmid:22020111 path(MESH:"Alzheimer Disease") increases p(HGNC:NQO1)
pmid:22020111 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:NQO1)
pmid:22020111 path(MESH:"Alzheimer Disease") increases p(HGNC:PHF1)
pmid:22020111 path(MESH:"Alzheimer Disease") increases p(HGNC:PRKCD)
pmid:22020111 path(MESH:"Alzheimer Disease") increases p(HGNC:RANBP9)
pmid:22020111 path(MESH:"Alzheimer Disease") increases p(HGNC:SOD1)
pmid:22020111 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:SOD1)
pmid:22020111 path(MESH:"Alzheimer Disease") positiveCorrelation bp(MESH:"Oxidative Stress")
pmid:23454242 path(MESH:"Alzheimer Disease") increases p(HGNC:SET)
pmid:24653673 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:SET)
pmid:22299660 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:SET)
pmid:23454242 path(MESH:"Alzheimer Disease") decreases act(p(FPLX:PPP2))
pmid:22299660 path(MESH:"Alzheimer Disease") negativeCorrelation act(p(FPLX:PPP2))
pmid:22299660 path(MESH:"Alzheimer Disease") negativeCorrelation act(p(FPLX:PPP2))
pmid:24653673 path(MESH:"Alzheimer Disease") association p(HGNC:GSK3B)
pmid:24653673 path(MESH:"Alzheimer Disease") association a(MESH:"Receptors, N-Methyl-D-Aspartate")
pmid:24653673 path(MESH:"Alzheimer Disease") association p(HGNC:GRM5)
pmid:24653673 path(MESH:"Alzheimer Disease") negativeCorrelation act(complex(GO:"protein phosphatase type 2A complex"))
pmid:24653673 path(MESH:"Alzheimer Disease") positiveCorrelation complex(GO:"protein phosphatase type 2A complex")
pmid:24653673 path(MESH:"Alzheimer Disease") negativeCorrelation act(complex(GO:"protein phosphatase type 2A complex"))
pmid:24653673 path(MESH:"Alzheimer Disease") negativeCorrelation g(HGNC:PPP2CA)
pmid:24653673 path(MESH:"Alzheimer Disease") negativeCorrelation r(HGNC:PPP2CA)
pmid:22299660 path(MESH:"Alzheimer Disease") negativeCorrelation r(HGNC:PPP2CA)
pmid:22299660 path(MESH:"Alzheimer Disease") causesNoChange r(HGNC:PPP2CA)
pmid:24653673 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:PPP2CA)
pmid:26631930 path(MESH:"Alzheimer Disease") negativeCorrelation act(p(HGNC:PPP2CA))
pmid:24653673 path(MESH:"Alzheimer Disease") negativeCorrelation g(HGNC:PPP2CB)
pmid:24653673 path(MESH:"Alzheimer Disease") negativeCorrelation r(HGNC:PPP2CB)
pmid:22299660 path(MESH:"Alzheimer Disease") negativeCorrelation r(HGNC:PPP2CB)
pmid:24653673 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:PPP2CB)
pmid:24653673 path(MESH:"Alzheimer Disease") negativeCorrelation r(HGNC:PPP2R2C)
pmid:24653673 path(MESH:"Alzheimer Disease") negativeCorrelation r(HGNC:PPP2R5E)
pmid:24653673 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:PPP2R2A)
pmid:22299660 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:PPP2R2A)
pmid:24653673 path(MESH:"Alzheimer Disease") negativeCorrelation p(FPLX:PPP2, pmod(Me))
pmid:24653673 path(MESH:"Alzheimer Disease") negativeCorrelation p(FPLX:PPP2, pmod(Me))
pmid:24653673 path(MESH:"Alzheimer Disease") negativeCorrelation p(FPLX:PPP2, pmod(Me))
pmid:29281045 path(MESH:"Alzheimer Disease") decreases p(FPLX:PPP2, pmod(Me))
pmid:24653673 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:SET, frag("?"))
pmid:24653673 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:PTPA)
pmid:24653673 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Thr, 231))
pmid:17403556 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Thr, 231))
pmid:17403556 path(MESH:"Alzheimer Disease") increases p(HGNC:MAPT, pmod(Ph, Thr, 231))
pmid:22253473 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Thr, 231))
pmid:24653673 path(MESH:"Alzheimer Disease") negativeCorrelation complex(p(HGNC:PPP2CA), p(HGNC:PPP2R1A), p(HGNC:PPP2R2A))
pmid:24653673 path(MESH:"Alzheimer Disease") negativeCorrelation complex(p(HGNC:PPP2CA), p(HGNC:PPP2R1A), p(HGNC:PPP2R2A))
pmid:24653673 path(MESH:"Alzheimer Disease") negativeCorrelation complex(p(HGNC:PPP2CB), p(HGNC:PPP2R1A), p(HGNC:PPP2R2A))
pmid:24653673 path(MESH:"Alzheimer Disease") negativeCorrelation complex(p(HGNC:PPP2CB), p(HGNC:PPP2R1A), p(HGNC:PPP2R2A))
pmid:24653673 path(MESH:"Alzheimer Disease") negativeCorrelation complex(p(HGNC:MAPT), p(HGNC:PPP2CA), p(HGNC:PPP2R1A), p(HGNC:PPP2R2A))
pmid:24653673 path(MESH:"Alzheimer Disease") negativeCorrelation complex(p(HGNC:MAPT), p(HGNC:PPP2CB), p(HGNC:PPP2R1A), p(HGNC:PPP2R2A))
pmid:24653673 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph))
pmid:8282104 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph))
pmid:24027553 path(MESH:"Alzheimer Disease") regulates p(HGNC:MAPT, pmod(Ph))
pmid:29191965 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph))
pmid:29191965 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph))
pmid:29311797 path(MESH:"Alzheimer Disease") association p(HGNC:MAPT, pmod(Ph))
pmid:26458742 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph))
pmid:26631930 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph))
pmid:26631930 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph))
pmid:22817713 path(MESH:"Alzheimer Disease") increases p(HGNC:MAPT, pmod(Ph))
pmid:12428809 path(MESH:"Alzheimer Disease") association a(HBP:"straight filaments")
pmid:12428809 path(MESH:"Alzheimer Disease") positiveCorrelation p(HBP:"4R tau")
pmid:26631930 path(MESH:"Alzheimer Disease") positiveCorrelation p(HBP:"4R tau")
pmid:12428809 path(MESH:"Alzheimer Disease") negativeCorrelation bp(GO:"axonal transport")
pmid:22908190 path(MESH:"Alzheimer Disease") negativeCorrelation bp(GO:"axonal transport")
pmid:12428809 path(MESH:"Alzheimer Disease") association p(HGNC:MAPT, pmod(Ph, Ser, 396), pmod(Ph, Ser, 404))
pmid:21882945 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Ser, 396), pmod(Ph, Ser, 404))
pmid:22299660 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Ser, 198))
pmid:23088643 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Ser, 198))
pmid:22299660 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Ser, 199))
pmid:26458742 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Ser, 199))
pmid:23088643 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Ser, 199))
pmid:22299660 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Ser, 202))
pmid:29191965 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Ser, 202))
pmid:23088643 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Ser, 202))
pmid:22299660 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Ser, 396))
pmid:22419736 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Ser, 396))
pmid:28420982 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Ser, 396))
pmid:26458742 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Ser, 396))
pmid:22299660 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Ser, 404))
pmid:22419736 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Ser, 404))
pmid:26458742 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Ser, 404))
pmid:22299660 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Ser, 422))
pmid:29191965 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Ser, 422))
pmid:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Ser, 422))
pmid:27373205 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Ser, 422))
pmid:23088643 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Ser, 422))
pmid:22299660 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Ser, 262))
pmid:29758300 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Ser, 262))
pmid:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Ser, 262))
pmid:22299660 path(MESH:"Alzheimer Disease") negativeCorrelation p(FPLX:PPP2C)
pmid:22299660 path(MESH:"Alzheimer Disease") negativeCorrelation p(FPLX:PPP2C, pmod(Me, Leu, 309))
pmid:22299660 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:ICMT)
pmid:22299660 path(MESH:"Alzheimer Disease") positiveCorrelation p(FPLX:PPP2C, pmod(Ph, Tyr, 307))
pmid:21722302 path(MESH:"Alzheimer Disease") association path(HBP:Neurodegeneration)
pmid:21722302 path(MESH:"Alzheimer Disease") association bp(HBP:"protein aggregation")
pmid:21722302 path(MESH:"Alzheimer Disease") association path(HP:"Senile plaques")
pmid:21722302 path(MESH:"Alzheimer Disease") association p(PFAM:Presenilin, var("?"))
pmid:21722302 path(MESH:"Alzheimer Disease") increases p(MESH:"Presenilin-1")
pmid:21722302 path(MESH:"Alzheimer Disease") negativeCorrelation p(MESH:"molecular chaperone GRP78")
pmid:21722302 path(MESH:"Alzheimer Disease") association p(HGNC:XBP1)
pmid:21722302 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:XBP1)
pmid:21722302 path(MESH:"Alzheimer Disease") decreases bp(MESH:"Unfolded Protein Response")
pmid:21722302 path(MESH:"Alzheimer Disease") association a(GO:autophagosome)
pmid:29758300 path(MESH:"Alzheimer Disease") increases a(GO:autophagosome)
pmid:22908190 path(MESH:"Alzheimer Disease") positiveCorrelation a(GO:autophagosome)
pmid:18930136 path(MESH:"Alzheimer Disease") positiveCorrelation a(GO:autophagosome)
pmid:18930136 path(MESH:"Alzheimer Disease") positiveCorrelation a(GO:autophagosome)
pmid:21722302 path(MESH:"Alzheimer Disease") negativeCorrelation bp(GO:autophagy)
pmid:29758300 path(MESH:"Alzheimer Disease") negativeCorrelation bp(GO:autophagy)
pmid:22908190 path(MESH:"Alzheimer Disease") association bp(GO:autophagy)
pmid:22908190 path(MESH:"Alzheimer Disease") association bp(GO:autophagy)
pmid:25437566 path(MESH:"Alzheimer Disease") decreases p(HGNC:HSP90AB1)
pmid:25437566 path(MESH:"Alzheimer Disease") decreases p(HGNC:HSPA8)
pmid:25437566 path(MESH:"Alzheimer Disease") decreases p(HGNC:HSPA14)
pmid:25437566 path(MESH:"Alzheimer Disease") decreases p(HGNC:TCP1)
pmid:27491084 path(MESH:"Alzheimer Disease") decreases p(HGNCGENEFAMILY:"DNAJ (HSP40) heat shock proteins")
pmid:27491084 path(MESH:"Alzheimer Disease") increases p(HGNC:HSPB1)
pmid:27491084 path(MESH:"Alzheimer Disease") increases p(HGNC:CRYAB)
pmid:27491084 path(MESH:"Alzheimer Disease") increases p(FPLX:HSPB)
pmid:29758300 path(MESH:"Alzheimer Disease") negativeCorrelation bp(GO:macroautophagy)
pmid:29758300 path(MESH:"Alzheimer Disease") negativeCorrelation bp(GO:macroautophagy)
pmid:29758300 path(MESH:"Alzheimer Disease") negativeCorrelation bp(GO:macroautophagy)
pmid:29758300 path(MESH:"Alzheimer Disease") negativeCorrelation bp(GO:macroautophagy)
pmid:25784053 path(MESH:"Alzheimer Disease") negativeCorrelation bp(GO:macroautophagy)
pmid:29758300 path(MESH:"Alzheimer Disease") increases complex(a(GO:autophagosome), a(HBP:"dystrophic neurite"))
pmid:29758300 path(MESH:"Alzheimer Disease") positiveCorrelation a(GO:autolysosome)
pmid:23528736 path(MESH:"Alzheimer Disease") increases a(GO:autolysosome)
pmid:23528736 path(MESH:"Alzheimer Disease") increases a(GO:autolysosome)
pmid:29758300 path(MESH:"Alzheimer Disease") negativeCorrelation bp(GO:"lysosomal protein catabolic process")
pmid:22908190 path(MESH:"Alzheimer Disease") negativeCorrelation bp(GO:"lysosomal protein catabolic process")
pmid:23528736 path(MESH:"Alzheimer Disease") decreases bp(GO:"lysosomal protein catabolic process")
pmid:29758300 path(MESH:"Alzheimer Disease") association p(HGNC:PSEN1, var("?"))
pmid:29758300 path(MESH:"Alzheimer Disease") increases a(GO:lysosome)
pmid:22908190 path(MESH:"Alzheimer Disease") positiveCorrelation a(GO:lysosome)
pmid:22908190 path(MESH:"Alzheimer Disease") negativeCorrelation act(a(GO:lysosome))
pmid:29758300 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:SNCA)
pmid:29758300 path(MESH:"Alzheimer Disease") negativeCorrelation bp(GO:endocytosis)
pmid:22908190 path(MESH:"Alzheimer Disease") negativeCorrelation bp(GO:endocytosis)
pmid:22908190 path(MESH:"Alzheimer Disease") negativeCorrelation bp(GO:endocytosis)
pmid:29758300 path(MESH:"Alzheimer Disease") association a(HBP:"alpha-synuclein aggregates")
pmid:29758300 path(MESH:"Alzheimer Disease") positiveCorrelation a(HBP:"alpha-synuclein aggregates")
pmid:29758300 path(MESH:"Alzheimer Disease") positiveCorrelation a(CHEBI:ceramide)
pmid:29758300 path(MESH:"Alzheimer Disease") association p(HGNC:TFEB)
pmid:29758300 path(MESH:"Alzheimer Disease") association p(HGNC:PICALM, var("?"))
pmid:26195256 path(MESH:"Alzheimer Disease") association p(HGNC:PICALM, var("?"))
pmid:29758300 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:BIN1)
pmid:29758300 path(MESH:"Alzheimer Disease") association p(HGNC:VPS35, var("?"))
pmid:29758300 path(MESH:"Alzheimer Disease") association p(HGNC:SORL1)
pmid:29758300 path(MESH:"Alzheimer Disease") increases bp(GO:mitophagy)
pmid:14556719 path(MESH:"Alzheimer Disease") decreases bp(GO:"short-term memory")
pmid:14556719 path(MESH:"Alzheimer Disease") negativeCorrelation act(p(HGNC:UBA1))
pmid:14556719 path(MESH:"Alzheimer Disease") negativeCorrelation act(p(HGNC:UBA2))
pmid:14556719 path(MESH:"Alzheimer Disease") negativeCorrelation bp(GO:"proteasome-mediated ubiquitin-dependent protein catabolic process")
pmid:23528736 path(MESH:"Alzheimer Disease") negativeCorrelation bp(GO:"proteasome-mediated ubiquitin-dependent protein catabolic process")
pmid:29626319 path(MESH:"Alzheimer Disease") decreases bp(GO:"proteasome-mediated ubiquitin-dependent protein catabolic process")
pmid:22908190 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:PRKN)
pmid:23528736 path(MESH:"Alzheimer Disease") association p(HGNC:PRKN)
pmid:22908190 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ub))
pmid:22908190 path(MESH:"Alzheimer Disease") positiveCorrelation p(HBP:"UBB+1")
pmid:23528736 path(MESH:"Alzheimer Disease") positiveCorrelation p(HBP:"UBB+1")
pmid:22908190 path(MESH:"Alzheimer Disease") association p(HGNC:UCHL1)
pmid:22908190 path(MESH:"Alzheimer Disease") association p(HGNC:UBQLN1)
pmid:22908190 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:UBQLN1, var("?"))
pmid:22908190 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:RAB7A)
pmid:22908190 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:RAB5A)
pmid:22908190 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:RAB4A)
pmid:22908190 path(MESH:"Alzheimer Disease") positiveCorrelation a(HBP:"dystrophic neurite")
pmid:22908190 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:APP, var("?"))
pmid:22908190 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:APP, var("?"))
pmid:22908190 path(MESH:"Alzheimer Disease") association g(HBP:"APOE e4")
pmid:25784053 path(MESH:"Alzheimer Disease") negativeCorrelation act(p(FPLX:Proteasome))
pmid:8282104 path(MESH:"Alzheimer Disease") positiveCorrelation p(FPLX:ERK)
pmid:8282104 path(MESH:"Alzheimer Disease") positiveCorrelation p(FPLX:GSK3)
pmid:30116051 path(MESH:"Alzheimer Disease") decreases p(HGNC:SIRT1)
pmid:30116051 path(MESH:"Alzheimer Disease") positiveCorrelation g(HGNC:PSEN1, var("?"))
pmid:26195256 path(MESH:"Alzheimer Disease") association g(HGNC:PSEN1, var("?"))
pmid:30116051 path(MESH:"Alzheimer Disease") negativeCorrelation a(CHEBI:"selenium(2+)")
pmid:30116051 path(MESH:"Alzheimer Disease") increases act(p(HGNC:ABL1))
pmid:30116051 path(MESH:"Alzheimer Disease") decreases p(HGNC:MME)
pmid:30116051 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:PLG)
pmid:29024336 path(MESH:"Alzheimer Disease") increases path(MESH:"Proteostasis Deficiencies")
pmid:29215007 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, var("?"))
pmid:24027553 path(MESH:"Alzheimer Disease") association p(HGNC:PIN1)
pmid:24027553 path(MESH:"Alzheimer Disease") increases a(CHEBI:Thrombin, loc(MESH:Microvessels))
pmid:24027553 path(MESH:"Alzheimer Disease") increases a(CHEBI:Thrombin, loc(MESH:"Cerebrospinal Fluid"))
pmid:24027553 path(MESH:"Alzheimer Disease") positiveCorrelation a(CHEBI:Thrombin, loc(MESH:Neurons))
pmid:24027553 path(MESH:"Alzheimer Disease") positiveCorrelation a(CHEBI:Thrombin, loc(MESH:Astrocytes))
pmid:24027553 path(MESH:"Alzheimer Disease") association bp(HBP:"APP processing")
pmid:24027553 path(MESH:"Alzheimer Disease") increases act(p(HGNC:CAPN2))
pmid:24027553 path(MESH:"Alzheimer Disease") positiveCorrelation act(p(HGNC:CASP3))
pmid:24027553 path(MESH:"Alzheimer Disease") positiveCorrelation act(p(HGNC:CASP6))
pmid:24027553 path(MESH:"Alzheimer Disease") negativeCorrelation bp(GO:"proteasomal protein catabolic process")
pmid:24027553 path(MESH:"Alzheimer Disease") increases complex(p(HGNC:MAPT), p(HGNCGENEFAMILY:Proteasome))
pmid:24027553 path(MESH:"Alzheimer Disease") positiveCorrelation a(MESH:Autophagosomes)
pmid:23528736 path(MESH:"Alzheimer Disease") increases a(MESH:Autophagosomes)
pmid:23528736 path(MESH:"Alzheimer Disease") increases a(MESH:Autophagosomes)
pmid:24027553 path(MESH:"Alzheimer Disease") positiveCorrelation a(MESH:Lysosomes)
pmid:24027553 path(MESH:"Alzheimer Disease") decreases bp(MESH:Autophagy)
pmid:27574109 path(MESH:"Alzheimer Disease") positiveCorrelation a(HBP:"3R tau")
pmid:27574109 path(MESH:"Alzheimer Disease") positiveCorrelation a(HBP:"4R tau")
pmid:27574109 path(MESH:"Alzheimer Disease") positiveCorrelation a(HBP:"phosphatase-activating domain")
pmid:27574109 path(MESH:"Alzheimer Disease") positiveCorrelation a(HBP:"Tau oligomers")
pmid:27574109 path(MESH:"Alzheimer Disease") positiveCorrelation a(HBP:"Tau oligomers")
pmid:25887395 path(MESH:"Alzheimer Disease") positiveCorrelation a(HBP:"Tau oligomers")
pmid:28420982 path(MESH:"Alzheimer Disease") positiveCorrelation a(HBP:"Tau oligomers")
pmid:26631930 path(MESH:"Alzheimer Disease") positiveCorrelation a(HBP:"Tau oligomers")
pmid:22817713 path(MESH:"Alzheimer Disease") increases a(HBP:"Tau oligomers")
pmid:27574109 path(MESH:"Alzheimer Disease") positiveCorrelation composite(a(HBP:"phosphatase-activating domain"), p(HGNC:MAPT))
pmid:21734277 path(MESH:"Alzheimer Disease") increases p(HBP:"phosphatase-activating domain")
pmid:21734277 path(MESH:"Alzheimer Disease") increases p(HBP:"phosphatase-activating domain")
pmid:23528736 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:UBB)
pmid:23528736 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:UBC)
pmid:23528736 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:UBA52)
pmid:23528736 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:RPS27A)
pmid:23528736 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNCGENEFAMILY:"Ubiquitin like modifier activating enzymes")
pmid:23528736 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNCGENEFAMILY:"Ubiquitin conjugating enzymes E2")
pmid:23528736 path(MESH:"Alzheimer Disease") association p(HGNC:STUB1)
pmid:29311797 path(MESH:"Alzheimer Disease") association p(HGNC:STUB1)
pmid:23528736 path(MESH:"Alzheimer Disease") association p(HGNC:RNF182)
pmid:23528736 path(MESH:"Alzheimer Disease") association p(HGNC:UCHL1, var("?"))
pmid:23528736 path(MESH:"Alzheimer Disease") decreases bp(MESH:Proteolysis)
pmid:29988016 path(MESH:"Alzheimer Disease") positiveCorrelation a(HBP:"Tau aggregates")
pmid:27373205 path(MESH:"Alzheimer Disease") positiveCorrelation a(HBP:"Tau aggregates")
pmid:26631930 path(MESH:"Alzheimer Disease") positiveCorrelation a(HBP:"Tau aggregates")
pmid:22817713 path(MESH:"Alzheimer Disease") positiveCorrelation a(HBP:"Tau aggregates")
pmid:21882945 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Ser, 202), pmod(Ph, Thr, 205))
pmid:21882945 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:BAG1)
pmid:30126037 path(MESH:"Alzheimer Disease") association bp(MESH:"Cerebrovascular Circulation")
pmid:22419736 path(MESH:"Alzheimer Disease") increases p(HGNC:AK1)
pmid:22419736 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:AK1)
pmid:22419736 path(MESH:"Alzheimer Disease") negativeCorrelation p(FPLX:AMPK, pmod(Ph, Thr, 172))
pmid:29191965 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Thr, 205))
pmid:30985105 path(MESH:"Alzheimer Disease") negativeCorrelation act(p(HGNC:OGT))
pmid:30985105 path(MESH:"Alzheimer Disease") decreases p(HGNC:OGT)
pmid:25374103 path(MESH:"Alzheimer Disease") decreases complex(a(GO:microtubule), p(HGNC:MAPT))
pmid:25374103 path(MESH:"Alzheimer Disease") decreases p(HGNC:MAPT, pmod(HBP:misfolded))
pmid:28877763 path(MESH:"Alzheimer Disease") increases bp(GO:"microglial cell activation")
pmid:28420982 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Thr, 181))
pmid:29311797 path(MESH:"Alzheimer Disease") isA path(MESH:Tauopathies)
pmid:29311797 path(MESH:"Alzheimer Disease") decreases p(HGNC:PPID)
pmid:29311797 path(MESH:"Alzheimer Disease") increases p(HGNC:FKBP5)
pmid:29311797 path(MESH:"Alzheimer Disease") decreases p(HGNC:FKBP4)
pmid:29311797 path(MESH:"Alzheimer Disease") decreases act(p(HGNC:PPP5C))
pmid:29311797 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:AHSA1)
pmid:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Tyr, 18))
pmid:26631930 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Tyr, 18))
pmid:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Ser, 68))
pmid:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Thr, 69))
pmid:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Thr, 71))
pmid:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Ser, 113))
pmid:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Thr, 123))
pmid:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Thr, 153))
pmid:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Thr, 175))
pmid:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Thr, 184))
pmid:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Ser, 185))
pmid:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Ser, 191))
pmid:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Tyr, 197))
pmid:23088643 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Tyr, 197))
pmid:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Ser, 208))
pmid:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Ser, 210))
pmid:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Ser, 214))
pmid:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Ser, 237))
pmid:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Ser, 238))
pmid:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Ser, 258))
pmid:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Ser, 289))
pmid:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Ser, 356))
pmid:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Tyr, 394))
pmid:26631930 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Tyr, 394))
pmid:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Thr, 403))
pmid:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Ser, 409))
pmid:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Ser, 435))
pmid:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Thr, 427))
pmid:26751493 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Ser, 433))
pmid:26195256 path(MESH:"Alzheimer Disease") association g(HGNC:PSEN2, var("?"))
pmid:26195256 path(MESH:"Alzheimer Disease") association g(HGNC:APP, var("?"))
pmid:26195256 path(MESH:"Alzheimer Disease") association p(HGNC:TREM2, var("?"))
pmid:26195256 path(MESH:"Alzheimer Disease") association p(HGNC:CLU, var("?"))
pmid:26195256 path(MESH:"Alzheimer Disease") positiveCorrelation path(MESH:Atrophy)
pmid:26195256 path(MESH:"Alzheimer Disease") decreases path(MESH:Atrophy)
pmid:26195256 path(MESH:"Alzheimer Disease") negativeCorrelation a(MESH:"Cerebral Cortex")
pmid:26195256 path(MESH:"Alzheimer Disease") positiveCorrelation a(MESH:"Cerebral Ventricles")
pmid:26195256 path(MESH:"Alzheimer Disease") decreases bp(GO:"glucose metabolic process")
pmid:26195256 path(MESH:"Alzheimer Disease") negativeCorrelation p(MESH:Neprilysin)
pmid:26195256 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MMP2)
pmid:26195256 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:LRP1)
pmid:26195256 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:ABCB1)
pmid:29626319 path(MESH:"Alzheimer Disease") decreases p(HGNC:ABCB1)
pmid:26195256 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:AGER)
pmid:26195256 path(MESH:"Alzheimer Disease") negativeCorrelation bp(HBP:"perivascular drainage pathways")
pmid:26195256 path(MESH:"Alzheimer Disease") negativeCorrelation a(MESH:"Cerebrospinal Fluid")
pmid:26195256 path(MESH:"Alzheimer Disease") negativeCorrelation act(p(HGNC:AQP1))
pmid:26195256 path(MESH:"Alzheimer Disease") increases path(MESH:"Calcification, Physiologic")
pmid:26195256 path(MESH:"Alzheimer Disease") increases path(MESH:Fibrosis)
pmid:26631930 path(MESH:"Alzheimer Disease") positiveCorrelation p(HBP:"3R tau")
pmid:26631930 path(MESH:"Alzheimer Disease") decreases p(HGNC:MAPT, pmod(Ac, Lys, 259))
pmid:26631930 path(MESH:"Alzheimer Disease") decreases p(HGNC:MAPT, pmod(Ac, Lys, 290))
pmid:26631930 path(MESH:"Alzheimer Disease") decreases p(HGNC:MAPT, pmod(Ac, Lys, 321))
pmid:26631930 path(MESH:"Alzheimer Disease") decreases p(HGNC:MAPT, pmod(Ac, Lys, 353))
pmid:26631930 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ac, Lys, 280))
pmid:29276758 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ac, Lys, 280))
pmid:21427723 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ac, Lys, 280))
pmid:26631930 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ac, Lys, 174))
pmid:26631930 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(NGlyco))
pmid:26631930 path(MESH:"Alzheimer Disease") decreases p(HGNC:MAPT, pmod(OGlyco))
pmid:26631930 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(HBP:nitration, Tyr, 18))
pmid:26631930 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(HBP:nitration, Tyr, 29))
pmid:17050703 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(HBP:nitration, Tyr, 29))
pmid:26631930 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(HBP:nitration, Tyr, 394))
pmid:26631930 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:MAPT, pmod(Me))
pmid:26631930 path(MESH:"Alzheimer Disease") increases p(HGNC:MAPT, frag("?"))
pmid:26631930 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, frag("26_230"))
pmid:26631930 path(MESH:"Alzheimer Disease") increases a(CHEBI:"iron(0)")
pmid:22817713 path(MESH:"Alzheimer Disease") association a(MESH:"Neuropil Threads")
pmid:29626319 path(MESH:"Alzheimer Disease") decreases bp(GO:"lysosomal microautophagy")
pmid:29626319 path(MESH:"Alzheimer Disease") positiveCorrelation act(p(HGNC:ACE))
pmid:29626319 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:SERPINF2)
pmid:29626319 path(MESH:"Alzheimer Disease") negativeCorrelation act(p(HGNC:SERPINF2))
pmid:29626319 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:PICALM)
pmid:27260836 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:PICALM)
pmid:29626319 path(MESH:"Alzheimer Disease") decreases tloc(a(CHEBI:water), fromLoc(GO:"extracellular region"), toLoc(MESH:"Cerebrospinal Fluid"))
pmid:25974414 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, var("p.Asp13*"))
pmid:25974414 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, var("p.Asp25*"))
pmid:25974414 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, var("p.Asp368*"))
pmid:25974414 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, var("p.Glu391*"))
pmid:25974414 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, var("p.Asp421*"))
pmid:24869773 path(MESH:"Alzheimer Disease") association p(HGNC:MAPT, pmod(Me, Lys, 311))
pmid:23531502 path(MESH:"Alzheimer Disease") positiveCorrelation act(a(CHEBI:acrolein))
pmid:19251756 path(MESH:"Alzheimer Disease") negativeCorrelation bp(GO:"canonical glycolysis")
pmid:19251756 path(MESH:"Alzheimer Disease") negativeCorrelation a(CHEBI:ATP)
pmid:19251756 path(MESH:"Alzheimer Disease") positiveCorrelation p(INTERPRO:"Triosephosphate isomerase", pmod(NO, Tyr, 164))
pmid:19251756 path(MESH:"Alzheimer Disease") positiveCorrelation p(INTERPRO:"Triosephosphate isomerase", pmod(NO, Tyr, 208))
pmid:11738469 path(MESH:"Alzheimer Disease") positiveCorrelation act(p(ECCODE:"2.3.2.13"))
pmid:8985134 path(MESH:"Alzheimer Disease") positiveCorrelation act(p(ECCODE:"2.3.2.13"))
pmid:9099822 path(MESH:"Alzheimer Disease") increases act(p(HGNCGENEFAMILY:Transglutaminases))
pmid:20096481 path(MESH:"Alzheimer Disease") positiveCorrelation g(DBSNP:rs2651206)
pmid:21548880 path(MESH:"Alzheimer Disease") positiveCorrelation g(DBSNP:rs2651206)
pmid:20096481 path(MESH:"Alzheimer Disease") positiveCorrelation g(DBSNP:rs10807287)
pmid:20096481 path(MESH:"Alzheimer Disease") positiveCorrelation g(DBSNP:rs7764257)
pmid:11943212 path(MESH:"Alzheimer Disease") positiveCorrelation path(HBP:"granulovacuolar degeneration")
pmid:23666762 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MARK4)
pmid:23666762 path(MESH:"Alzheimer Disease") positiveCorrelation complex(p(HGNC:MAPT), p(HGNC:MARK4))
pmid:28176663 path(MESH:"Alzheimer Disease") increases r(HGNC:GSK3B)
pmid:26118667 path(MESH:"Alzheimer Disease") positiveCorrelation p(HBP:"CDK5R1 p25")
pmid:21910444 path(MESH:"Alzheimer Disease") increases p(HGNC:MAPK1)
pmid:21910444 path(MESH:"Alzheimer Disease") increases p(HGNC:PRKCB)
pmid:24401760 path(MESH:"Alzheimer Disease") increases p(HGNC:ITPKB)
pmid:24401760 path(MESH:"Alzheimer Disease") positiveCorrelation path(HBP:Astrogliosis)
pmid:24401760 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:APP, frag("672_711"))
pmid:29540553 path(MESH:"Alzheimer Disease") negativeCorrelation p(MGI:Sirt3)
pmid:29559585 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:GAPDH, pmod(NO))
pmid:21427723 path(MESH:"Alzheimer Disease") isA path(HBP:"4R tauopathy")
pmid:19732809 path(MESH:"Alzheimer Disease") negativeCorrelation p(MESH:Proteins, pmod(HBP:"O-GlcNAcylation"))
pmid:19732809 path(MESH:"Alzheimer Disease") positiveCorrelation g(HGNC:OGA, var("?"))
pmid:27716675 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:SUMO1)
pmid:19765634 path(MESH:"Alzheimer Disease") positiveCorrelation g(DBSNP:rs761059)
pmid:29062069 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:MID1)
pmid:25001178 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:DUSP6)
pmid:25001178 path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:PPP1CA)
pmid:29281045 path(MESH:"Alzheimer Disease") decreases p(HGNC:LCMT1)
pmid:29281045 path(MESH:"Alzheimer Disease") increases p(HGNC:PPME1)
pmid:24964035 path(MESH:"Alzheimer Disease") negativeCorrelation p(FPLX:SMAD)
pmid:23157676 path(MESH:"Alzheimer Disease") positiveCorrelation p(HBP:"cis p-tau")
pmid:24561250 path(MESH:"Alzheimer Disease") association complex(GO:"NLRP3 inflammasome complex")
pmid:24561250 path(MESH:"Alzheimer Disease") positiveCorrelation bp(GO:aging)
pmid:24561250 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:PYCARD)
pmid:24561250 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:NLRC4)
pmid:24561250 path(MESH:"Alzheimer Disease") association complex(GO:"IPAF inflammasome complex")
pmid:27314526 path(MESH:"Alzheimer Disease") association complex(GO:"inflammasome complex")
pmid:27314526 path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:P2RX7)
pmid:25514383 bp(GO:"neuron cellular homeostasis") association complex(a(CHEBI:"amyloid-beta"), p(FPLX:CHRN))
pmid:30046111 bp(GO:aging) decreases bp(GO:"cerebrospinal fluid circulation")
pmid:30046111 bp(GO:aging) decreases act(a(HP:"interstitial fluid"))
pmid:30046111 bp(GO:aging) increases a(CHEBI:"amyloid-beta")
pmid:29626319 bp(GO:aging) positiveCorrelation a(CHEBI:"amyloid-beta")
pmid:29421605 bp(GO:aging) positiveCorrelation a(CHEBI:"amyloid-beta")
pmid:30046111 bp(GO:aging) decreases act(a(MESH:"Lymphatic Vessels"))
pmid:30046111 bp(GO:aging) negativeCorrelation act(a(MESH:"Lymphatic Vessels"))
pmid:30046111 bp(GO:aging) decreases tloc(a(CHEBI:macromolecule), fromLoc(GO:"extracellular space"), toLoc(MESH:"Intracellular Space"))
pmid:30046111 bp(GO:aging) association bp(GO:"immune response")
pmid:30046111 bp(GO:aging) association bp(GO:"inflammatory response")
pmid:30046111 bp(GO:aging) association bp(GO:"phospholipid metabolic process")
pmid:30046111 bp(GO:aging) association bp(GO:"extracellular matrix organization")
pmid:30046111 bp(GO:aging) association bp(GO:"cell adhesion")
pmid:30046111 bp(GO:aging) association bp(GO:"endothelial tube morphogenesis")
pmid:30046111 bp(GO:aging) decreases p(MGI:Cdk5r1)
pmid:30046111 bp(GO:aging) decreases p(MGI:Adamts3)
pmid:30046111 bp(GO:aging) decreases p(MGI:Fgfr3)
pmid:29196815 bp(GO:aging) increases path(MESH:"Alzheimer Disease")
pmid:24561250 bp(GO:aging) positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:29196815 bp(GO:aging) increases a(HBP:HBP00074)
pmid:25514383 bp(GO:aging) association path(MESH:Dementia)
pmid:27522251 bp(GO:aging) association p(MGI:Chrna7)
pmid:11230871 bp(GO:aging) negativeCorrelation complex(a(CHEBI:epibatidine), p(FPLX:CHRN))
pmid:11230871 bp(GO:aging) negativeCorrelation complex(a(CHEBI:epibatidine), p(FPLX:CHRN))
pmid:11230871 bp(GO:aging) causesNoChange r(HGNC:CHRNA3)
pmid:11230871 bp(GO:aging) negativeCorrelation r(HBP:"alpha-4-containing nAChR")
pmid:11230871 bp(GO:aging) negativeCorrelation r(HBP:"alpha-7-containing nAChR")
pmid:23454242 bp(GO:aging) increases p(HGNC:PPP2R2C)
pmid:23454242 bp(GO:aging) decreases p(HGNC:PPP2R2B)
pmid:28083634 bp(GO:aging) increases p(MGI:Otub1)
pmid:27491084 bp(GO:aging) decreases p(HGNCGENEFAMILY:"DNAJ (HSP40) heat shock proteins")
pmid:27491084 bp(GO:aging) decreases p(FPLX:HSPA)
pmid:27491084 bp(GO:aging) increases p(FPLX:HSPB)
pmid:14556719 bp(GO:aging) negativeCorrelation act(complex(GO:"proteasome complex"))
pmid:22908190 bp(GO:aging) negativeCorrelation act(complex(GO:"proteasome complex"))
pmid:22908190 bp(GO:aging) negativeCorrelation act(complex(GO:"proteasome complex"))
pmid:14556719 bp(GO:aging) negativeCorrelation bp(GO:"proteasome-mediated ubiquitin-dependent protein catabolic process")
pmid:14556719 bp(GO:aging) increases p(HGNC:PRNP)
pmid:23746257 bp(GO:aging) decreases bp(HBP:Proteostasis)
pmid:23746257 bp(GO:aging) decreases bp(HBP:Proteostasis)
pmid:24563850 bp(GO:aging) positiveCorrelation bp(HBP:"non-enzymatic protein modification")
pmid:24563850 bp(GO:aging) association bp(GO:"protein oxidation")
pmid:30145931 bp(GO:aging) increases p(HGNC:MAPT)
pmid:30145931 bp(GO:aging) decreases p(HGNC:MAPT)
pmid:21882945 bp(GO:aging) negativeCorrelation deg(p(HGNC:MAPT))
pmid:29238289 bp(GO:aging) increases p(HGNC:MAPT)
pmid:30116051 bp(GO:aging) negativeCorrelation act(p(HGNC:SIRT1))
pmid:30116051 bp(GO:aging) decreases a(CHEBI:"NAD(+)")
pmid:29024336 bp(GO:aging) increases path(MESH:"Proteostasis Deficiencies")
pmid:29024336 bp(GO:aging) increases path(MESH:"Proteostasis Deficiencies")
pmid:21882945 bp(GO:aging) positiveCorrelation p(HGNC:FKBP5)
pmid:29191965 bp(GO:aging) decreases bp(GO:locomotion)
pmid:28877763 bp(GO:aging) increases p(MGI:Syk, pmod(Ph))
pmid:28877763 bp(GO:aging) increases p(MGI:Syk, pmod(Ph))
pmid:28877763 bp(GO:aging) increases a(HBP:"Tau aggregates")
pmid:26631930 bp(GO:aging) positiveCorrelation a(HBP:"Tau aggregates")
pmid:28877763 bp(GO:aging) increases p(MGI:Mapt, pmod(HBP:hyperphosphorylation))
pmid:29626319 bp(GO:aging) negativeCorrelation p(HGNC:IDE)
pmid:25681682 bp(GO:aging) negativeCorrelation p(HGNC:AGER)
pmid:19118186 bp(GO:aging) decreases bp(GO:memory)
pmid:28877763 bp(GO:aging) increases a(HBP:"dystrophic neurite")
pmid:29421605 bp(GO:aging) positiveCorrelation p(RGD:Ptpn1)
pmid:29421605 bp(GO:aging) negativeCorrelation p(RGD:Irs1, pmod(Ph))
pmid:29421605 bp(GO:aging) negativeCorrelation p(RGD:Akt1, pmod(Ph))
pmid:29421605 bp(GO:aging) negativeCorrelation p(RGD:Gsk3b, pmod(Ph))
pmid:29421605 bp(GO:aging) negativeCorrelation p(RGD:Mtor, pmod(Ph))
pmid:29421605 bp(GO:aging) negativeCorrelation p(RGD:Ntrk2, pmod(Ph))
pmid:29421605 bp(GO:aging) positiveCorrelation p(RGD:Mapt, pmod(Ph))
pmid:24561250 bp(GO:aging) increases act(complex(GO:"NLRP1 inflammasome complex"))
pmid:24561250 bp(GO:aging) increases p(HGNC:IL1B)
pmid:24561250 bp(GO:aging) increases p(HGNC:IL18)
pmid:30046111 bp(GO:"cerebrospinal fluid circulation") decreases a(CHEBI:"amyloid-beta")
pmid:30046111 act(a(HP:"interstitial fluid")) decreases a(CHEBI:"amyloid-beta")
pmid:30046111 a(MESH:"Lymphatic Vessels") regulates bp(MESH:Homeostasis)
pmid:30046111 a(MESH:"Lymphatic Vessels") increases tloc(a(CHEBI:macromolecule), fromLoc(MESH:"Cerebrospinal Fluid"), toLoc(MESH:"Lymph Nodes"))
pmid:30046111 act(a(MESH:"Lymphatic Vessels")) association tloc(a(CHEBI:macromolecule), fromLoc(GO:"extracellular space"), toLoc(MESH:"Intracellular Space"))
pmid:30046111 act(a(MESH:"Lymphatic Vessels")) increases tloc(a(CHEBI:macromolecule), fromLoc(MESH:"Parenchymal Tissue"), toLoc(MESH:"Lymph Nodes"))
pmid:30046111 act(a(MESH:"Lymphatic Vessels")) increases tloc(a(CHEBI:macromolecule), fromLoc(HP:"interstitial fluid"), toLoc(MESH:"Lymph Nodes"))
pmid:30046111 act(a(MESH:"Lymphatic Vessels")) increases tloc(a(CHEBI:macromolecule), fromLoc(MESH:"Cerebrospinal Fluid"), toLoc(MESH:"Parenchymal Tissue"))
pmid:30046111 act(a(MESH:"Lymphatic Vessels")) increases bp(MESH:"Cerebrovascular Circulation")
pmid:30046111 act(a(MESH:"Lymphatic Vessels")) increases bp(MESH:"Cerebrovascular Circulation")
pmid:30046111 act(a(MESH:"Lymphatic Vessels")) association bp(MESH:"Cerebrovascular Circulation")
pmid:30046111 act(a(MESH:"Lymphatic Vessels")) positiveCorrelation bp(MESH:"Cerebrovascular Circulation")
pmid:30046111 act(a(MESH:"Lymphatic Vessels")) increases bp(GO:"cerebrospinal fluid secretion")
pmid:30046111 act(a(MESH:"Lymphatic Vessels")) increases tloc(a(CHEBI:"gadolinium atom"), fromLoc(GO:"extracellular space"), toLoc(MESH:"Cerebrospinal Fluid"))
pmid:30046111 act(a(MESH:"Lymphatic Vessels")) increases bp(GO:"fear response")
pmid:30046111 act(a(MESH:"Lymphatic Vessels")) increases path(MESH:"Spatial Learning")
pmid:30046111 act(a(MESH:"Lymphatic Vessels")) increases path(MESH:"Spatial Learning")
pmid:30046111 act(a(MESH:"Lymphatic Vessels")) increases bp(GO:memory)
pmid:30046111 act(a(MESH:"Lymphatic Vessels")) increases bp(GO:memory)
pmid:30046111 act(a(MESH:"Lymphatic Vessels")) association bp(GO:"gene expression")
pmid:30046111 act(a(MESH:"Lymphatic Vessels")) association path(MESH:"Huntington Disease")
pmid:30046111 act(a(MESH:"Lymphatic Vessels")) association path(MESH:"Parkinson Disease")
pmid:30046111 act(a(MESH:"Lymphatic Vessels")) association path(MESH:"Alzheimer Disease")
pmid:30046111 act(a(MESH:"Lymphatic Vessels")) association bp(GO:"excitatory chemical synaptic transmission")
pmid:30046111 act(a(MESH:"Lymphatic Vessels")) increases bp(GO:learning)
pmid:30046111 act(a(MESH:"Lymphatic Vessels")) increases bp(GO:cognition)
pmid:30046111 act(a(MESH:"Lymphatic Vessels")) association bp(GO:"neuronal signal transduction")
pmid:30046111 act(a(MESH:"Lymphatic Vessels")) regulates a(CHEBI:metabolite)
pmid:30046111 act(a(MESH:"Lymphatic Vessels")) regulates bp(MESH:Glycolysis)
pmid:30046111 act(a(MESH:"Lymphatic Vessels")) regulates bp(GO:"response to oxidative stress")
pmid:30046111 act(a(MESH:"Lymphatic Vessels")) regulates bp(GO:"cellular respiration")
pmid:30046111 act(a(MESH:"Lymphatic Vessels")) negativeCorrelation bp(GO:aging)
pmid:30046111 act(a(MESH:"Lymphatic Vessels")) increases act(p(MGI:Vegfc))
pmid:30046111 act(a(MESH:"Lymphatic Vessels")) decreases a(CHEBI:"amyloid-beta")
pmid:30046111 act(a(MESH:"Lymphatic Vessels")) negativeCorrelation a(CHEBI:"amyloid-beta")
pmid:30046111 act(a(MESH:"Lymphatic Vessels")) decreases a(CHEBI:"amyloid-beta")
pmid:30046111 act(a(MESH:"Lymphatic Vessels")) decreases a(CHEBI:"amyloid-beta")
pmid:30046111 a(MESH:"Lymphatic Vessels") decreases a(CHEBI:"amyloid-beta")
pmid:30046111 act(a(MESH:"Lymphatic Vessels")) decreases bp(GO:"macrophage migration")
pmid:30046111 act(a(MESH:"Lymphatic Vessels")) decreases a(MESH:Macrophages)
pmid:30046111 act(a(MESH:"Lymphatic Vessels")) negativeCorrelation path(MESH:Inflammation)
pmid:30046111 act(a(MESH:"Lymphatic Vessels")) decreases a(HBP:HBP00018)
pmid:30046111 tloc(a(CHEBI:macromolecule), fromLoc(GO:"extracellular space"), toLoc(MESH:"Intracellular Space")) association act(a(MESH:"Lymphatic Vessels"))
pmid:30046111 a(CHEBI:verteporfin) decreases a(MESH:"Lymphatic Vessels")
pmid:30046111 a(CHEBI:verteporfin) decreases act(a(MESH:"Lymphatic Vessels"))
pmid:30046111 a(CHEBI:verteporfin) decreases bp(MESH:"Cerebrovascular Circulation")
pmid:30046111 a(CHEBI:verteporfin) decreases tloc(a(CHEBI:"gadolinium atom"), fromLoc(GO:"extracellular space"), toLoc(MESH:"Cerebrospinal Fluid"))
pmid:30046111 bp(MESH:"Cerebrovascular Circulation") association act(a(MESH:"Lymphatic Vessels"))
pmid:30046111 bp(MESH:"Cerebrovascular Circulation") increases act(a(MESH:"Lymphatic Vessels"))
pmid:30046111 bp(MESH:"Cerebrovascular Circulation") positiveCorrelation act(a(MESH:"Lymphatic Vessels"))
pmid:30046111 bp(MESH:"Cerebrovascular Circulation") increases tloc(a(CHEBI:macromolecule), fromLoc(GO:"extracellular space"), toLoc(MESH:"Intracellular Space"))
pmid:30126037 bp(MESH:"Cerebrovascular Circulation") association p(MGI:Mapt, var("p.Pro301Leu"))
pmid:30126037 bp(MESH:"Cerebrovascular Circulation") association path(MESH:"Alzheimer Disease")
pmid:30126037 bp(MESH:"Cerebrovascular Circulation") association path(MESH:"Cognitive Dysfunction")
pmid:30046111 p(MGI:Aqp4) regulates tloc(a(CHEBI:macromolecule), fromLoc(GO:"extracellular space"), toLoc(MESH:"Intracellular Space"))
pmid:30046111 p(MGI:Aqp4) regulates tloc(a(CHEBI:macromolecule), fromLoc(MESH:"Intracellular Space"), toLoc(GO:"extracellular space"))
pmid:30046111 p(MGI:Aqp4) decreases a(CHEBI:"amyloid-beta")
pmid:30046111 p(MGI:Aqp4) increases bp(GO:cognition)
pmid:26195256 p(MGI:Aqp4) increases act(a(HBP:"Glymphatic System"))
pmid:19126755 bp(GO:cognition) positiveCorrelation p(HBP:"alpha-4 beta-2 nAChR")
pmid:19126755 bp(GO:cognition) positiveCorrelation p(HGNC:CHRNA7)
pmid:19126755 bp(GO:cognition) association act(p(HGNC:CHRNA7))
pmid:19721446 bp(GO:cognition) positiveCorrelation p(HGNC:CHRNA7)
pmid:19126755 bp(GO:cognition) negativeCorrelation path(MESH:"Alzheimer Disease")
pmid:24511233 bp(GO:cognition) association path(MESH:"Alzheimer Disease")
pmid:11230871 bp(GO:cognition) negativeCorrelation path(MESH:"Alzheimer Disease")
pmid:24511233 bp(GO:cognition) association path(MESH:Schizophrenia)
pmid:19721446 bp(GO:cognition) association path(MESH:Schizophrenia)
pmid:24511233 bp(GO:cognition) association a(MESH:Hippocampus)
pmid:24511233 bp(GO:cognition) association a(MESH:"Cerebral Cortex")
pmid:24511233 bp(GO:cognition) association bp(GO:"synaptic transmission, cholinergic")
pmid:26813123 bp(GO:cognition) association bp(GO:"synaptic transmission, cholinergic")
pmid:21482353 bp(GO:cognition) association bp(GO:"synaptic transmission, cholinergic")
pmid:24511233 bp(GO:cognition) association p(HGNC:CHRM1)
pmid:24511233 bp(GO:cognition) association p(HGNCGENEFAMILY:"Glutamate ionotropic receptor NMDA type subunits")
pmid:24511233 bp(GO:cognition) association a(MESH:"Prefrontal Cortex")
pmid:26813123 bp(GO:cognition) association bp(GO:"synaptic transmission, glutamatergic")
pmid:26813123 bp(GO:cognition) association a(CHEBI:acetylcholine)
pmid:11230871 bp(GO:cognition) negativeCorrelation a(CHEBI:acetylcholine)
pmid:25514383 bp(GO:cognition) association a(HP:"cholinergic neuron")
pmid:28445721 bp(GO:cognition) association p(FPLX:CHRN)
pmid:28445721 bp(GO:cognition) association p(FPLX:CHRN)
pmid:28445721 bp(GO:cognition) association p(FPLX:CHRN)
pmid:11230871 bp(GO:cognition) association p(FPLX:CHRN)
pmid:21482353 bp(GO:cognition) positiveCorrelation a(HBP:"alpha-4 beta-2 nAChR")
pmid:21482353 bp(GO:cognition) positiveCorrelation p(HGNC:CHRNA5, var("?"))
pmid:21482353 bp(GO:cognition) positiveCorrelation p(HGNC:CHRNA3, var("?"))
pmid:21482353 bp(GO:cognition) positiveCorrelation p(HGNC:CHRNB4, var("?"))
pmid:11230871 bp(GO:cognition) association complex(a(CHEBI:nicotine), p(FPLX:CHRN))
pmid:11230871 bp(GO:cognition) association a(CHEBI:neurotransmitter)
pmid:22908190 bp(GO:cognition) positiveCorrelation act(a(GO:synapse))
pmid:24027553 bp(GO:cognition) negativeCorrelation p(HBP:"Tau C3")
pmid:21882945 bp(GO:cognition) negativeCorrelation path(MESH:Tauopathies)
pmid:21882945 bp(GO:cognition) positiveCorrelation a(PUBCHEM:134222899)
pmid:21882945 bp(GO:cognition) positiveCorrelation a(CHEBI:"NMDA receptor antagonist")
pmid:30985105 bp(GO:cognition) association a(CHEBI:"amyloid-beta")
pmid:24808823 path(MESH:"Spatial Learning") negativeCorrelation p(MGI:Ttbk1)
pmid:24808823 path(MESH:"Spatial Learning") negativeCorrelation p(MGI:Cdk5)
pmid:24808823 path(MESH:"Spatial Learning") positiveCorrelation surf(p(MGI:Grin2b))
pmid:19293145 bp(GO:memory) association composite(p(HGNC:MAPK1), p(HGNC:MAPK3))
pmid:24511233 bp(GO:memory) association a(MESH:Hippocampus)
pmid:24511233 bp(GO:memory) association a(MESH:Hippocampus)
pmid:19721446 bp(GO:memory) association a(MESH:Hippocampus)
pmid:24511233 bp(GO:memory) association a(MESH:"Cerebral Cortex")
pmid:24511233 bp(GO:memory) association a(MESH:"Cerebral Cortex")
pmid:24511233 bp(GO:memory) association bp(GO:"long-term synaptic potentiation")
pmid:24511233 bp(GO:memory) association a(MESH:"Prefrontal Cortex")
pmid:17009926 bp(GO:memory) association p(FPLX:CHRN)
pmid:11230871 bp(GO:memory) association p(FPLX:CHRN)
pmid:26813123 bp(GO:memory) association bp(GO:"synaptic transmission, cholinergic")
pmid:21482353 bp(GO:memory) association bp(GO:"synaptic transmission, cholinergic")
pmid:26813123 bp(GO:memory) positiveCorrelation a(CHEBI:acetylcholine)
pmid:26813123 bp(GO:memory) association a(CHEBI:acetylcholine)
pmid:26813123 bp(GO:memory) positiveCorrelation a(MESH:"Cholinergic Neurons")
pmid:26813123 bp(GO:memory) negativeCorrelation bp(HBP:Neurodegeneration)
pmid:26813123 bp(GO:memory) association bp(MESH:"Synaptic Transmission")
pmid:26813123 bp(GO:memory) association p(HGNC:SYP)
pmid:24590577 bp(GO:memory) association p(HGNCGENEFAMILY:"Cholinergic receptors muscarinic")
pmid:24590577 bp(GO:memory) association p(HGNC:CHRM1)
pmid:19721446 bp(GO:memory) association p(HGNC:CHRNA7)
pmid:19721446 bp(GO:memory) association a(MESH:"Entorhinal Cortex")
pmid:30106381 bp(GO:memory) association p(HGNC:ADNP)
pmid:30106381 bp(GO:memory) association a(PUBCHEM:9832404)
pmid:30012004 bp(GO:memory) negativeCorrelation path(MESH:"Huntington Disease")
pmid:22908190 bp(GO:memory) association bp(GO:"proteasome-mediated ubiquitin-dependent protein catabolic process")
pmid:19118186 bp(GO:memory) negativeCorrelation p(MGI:Mapt)
pmid:28775333 bp(GO:memory) positiveCorrelation a(CHEBI:"(-)-epigallocatechin 3-gallate")
pmid:28775333 bp(GO:memory) negativeCorrelation p(MGI:Dyrk1a)
pmid:24355211 bp(GO:memory) negativeCorrelation p(HGNC:GSK3B)
pmid:27041503 bp(GO:memory) association p(HGNC:WWC1)
pmid:28771976 bp(GO:memory) association a(HBP:RGFP966)
pmid:21843595 bp(GO:memory) negativeCorrelation p(MGI:Sumo3)
pmid:30046111 bp(GO:"gene expression") association act(a(MESH:"Lymphatic Vessels"))
pmid:30046111 path(MESH:"Huntington Disease") association act(a(MESH:"Lymphatic Vessels"))
pmid:30663117 path(MESH:"Huntington Disease") association path(MESH:Chorea)
pmid:29687724 path(MESH:"Huntington Disease") association path(MESH:Chorea)
pmid:30663117 path(MESH:"Huntington Disease") association path(MESH:Dementia)
pmid:30012004 path(MESH:"Huntington Disease") positiveCorrelation path(MESH:Dementia)
pmid:30663117 path(MESH:"Huntington Disease") association path(MESH:"Deglutition Disorders")
pmid:30663117 path(MESH:"Huntington Disease") association path(MESH:Aphasia)
pmid:30663117 path(MESH:"Huntington Disease") association path(MESH:Seizures)
pmid:30663117 path(MESH:"Huntington Disease") association g(HGNC:MIR196A1)
pmid:30663117 path(MESH:"Huntington Disease") increases g(HGNC:MIR196A1)
pmid:30663117 path(MESH:"Huntington Disease") association g(HGNC:MIR206)
pmid:30663117 path(MESH:"Huntington Disease") association g(HGNC:MIR301B)
pmid:30663117 path(MESH:"Huntington Disease") association g(HGNC:MIR92B)
pmid:30663117 path(MESH:"Huntington Disease") association g(HGNC:MIR378B)
pmid:30663117 path(MESH:"Huntington Disease") association g(HGNC:MIR208B)
pmid:30663117 path(MESH:"Huntington Disease") association g(HGNC:MIR449A)
pmid:30663117 path(MESH:"Huntington Disease") decreases g(NCBIGENE:406915)
pmid:30663117 path(MESH:"Huntington Disease") increases g(MIRBASE:"hsa-mir-10b")
pmid:30663117 path(MESH:"Huntington Disease") increases g(HGNC:MIR196B)
pmid:30663117 path(MESH:"Huntington Disease") increases g(HGNC:MIR615)
pmid:30663117 path(MESH:"Huntington Disease") increases g(HGNC:MIR1247)
pmid:30663117 path(MESH:"Huntington Disease") decreases g(MGI:Mir22)
pmid:30663117 path(MESH:"Huntington Disease") decreases g(MGI:Mir29c)
pmid:30663117 path(MESH:"Huntington Disease") decreases g(MGI:"Mir128-1")
pmid:30663117 path(MESH:"Huntington Disease") decreases g(MGI:Mir132)
pmid:30663117 path(MESH:"Huntington Disease") decreases g(MGI:"Mir138-1")
pmid:30663117 path(MESH:"Huntington Disease") decreases g(MGI:"Mir218-1")
pmid:30663117 path(MESH:"Huntington Disease") decreases g(MGI:Mir222)
pmid:30663117 path(MESH:"Huntington Disease") decreases g(NCBIGENE:723931)
pmid:30663117 path(MESH:"Huntington Disease") decreases g(NCBIGENE:732489)
pmid:26813123 path(MESH:"Huntington Disease") negativeCorrelation act(p(HGNC:CHAT))
pmid:30012004 path(MESH:"Huntington Disease") positiveCorrelation bp(GO:"neuron death")
pmid:30012004 path(MESH:"Huntington Disease") positiveCorrelation bp(GO:"neuron death")
pmid:30012004 path(MESH:"Huntington Disease") positiveCorrelation path(MESH:Atrophy)
pmid:30012004 path(MESH:"Huntington Disease") positiveCorrelation path(HBP:Excitotoxicity)
pmid:30012004 path(MESH:"Huntington Disease") positiveCorrelation path(MESH:"Oxidative Stress")
pmid:30012004 path(MESH:"Huntington Disease") negativeCorrelation bp(MESH:"Energy Metabolism")
pmid:30012004 path(MESH:"Huntington Disease") positiveCorrelation path(HBP:"mitochondrial dysfunction")
pmid:30012004 path(MESH:"Huntington Disease") positiveCorrelation path(MESH:Inflammation)
pmid:30012004 path(MESH:"Huntington Disease") positiveCorrelation bp(GO:"apoptotic process")
pmid:30012004 path(MESH:"Huntington Disease") positiveCorrelation bp(GO:autophagy)
pmid:30012004 path(MESH:"Huntington Disease") negativeCorrelation bp(GO:"dopamine metabolic process")
pmid:30012004 path(MESH:"Huntington Disease") negativeCorrelation bp(GO:"D-glutamate metabolic process")
pmid:30012004 path(MESH:"Huntington Disease") negativeCorrelation bp(GO:"cannabinoid biosynthetic process")
pmid:30012004 path(MESH:"Huntington Disease") negativeCorrelation bp(GO:"adenosine catabolic process")
pmid:30012004 path(MESH:"Huntington Disease") negativeCorrelation a(MESH:"Gray Matter")
pmid:30012004 path(MESH:"Huntington Disease") negativeCorrelation a(MESH:"White Matter")
pmid:30012004 path(MESH:"Huntington Disease") negativeCorrelation bp(GO:"motor behavior")
pmid:29687724 path(MESH:"Huntington Disease") decreases bp(GO:"motor behavior")
pmid:30012004 path(MESH:"Huntington Disease") negativeCorrelation bp(GO:memory)
pmid:30012004 path(MESH:"Huntington Disease") negativeCorrelation bp(GO:"psychomotor behavior")
pmid:30012004 path(MESH:"Huntington Disease") negativeCorrelation bp(GO:"sensory perception")
pmid:30012004 path(MESH:"Huntington Disease") negativeCorrelation bp(GO:"visual learning")
pmid:29687724 path(MESH:"Huntington Disease") association path(MESH:"Neurodegenerative Diseases")
pmid:29687724 path(MESH:"Huntington Disease") association path(MESH:Cognition)
pmid:29687724 path(MESH:"Huntington Disease") decreases bp(GO:behavior)
pmid:29687724 path(MESH:"Huntington Disease") association path(MESH:Dystonia)
pmid:29687724 path(MESH:"Huntington Disease") association path(MESH:"Neural Pathways")
pmid:29687724 path(MESH:"Huntington Disease") association a(CHEBI:dopamine)
pmid:29687724 path(MESH:"Huntington Disease") association path(MESH:Depression)
pmid:29687724 path(MESH:"Huntington Disease") association path(MESH:"Motor Disorders")
pmid:29687724 path(MESH:"Huntington Disease") association path(MESH:"Schizophrenia, Disorganized")
pmid:29687724 path(MESH:"Huntington Disease") association path(MESH:"Cognitive Dysfunction")
pmid:29687724 path(MESH:"Huntington Disease") association a(CHEBI:amantadine)
pmid:29687724 path(MESH:"Huntington Disease") association a(PUBCHEM:9795739)
pmid:25437566 path(MESH:"Huntington Disease") decreases p(HGNC:HSP90AB1)
pmid:25437566 path(MESH:"Huntington Disease") decreases p(HGNC:HSPA8)
pmid:25437566 path(MESH:"Huntington Disease") decreases p(HGNC:HSPA14)
pmid:25437566 path(MESH:"Huntington Disease") decreases p(HGNC:TCP1)
pmid:14556719 path(MESH:"Huntington Disease") positiveCorrelation complex(a(MESH:"Inclusion Bodies"), a(MESH:Ubiquitin))
pmid:14556719 path(MESH:"Huntington Disease") positiveCorrelation complex(a(GO:"proteasome complex"), a(MESH:"Inclusion Bodies"))
pmid:25784053 path(MESH:"Huntington Disease") positiveCorrelation p(FPLX:HSPA)
pmid:25784053 path(MESH:"Huntington Disease") negativeCorrelation p(HGNC:ATF6)
pmid:18930136 path(MESH:"Huntington Disease") increases p(HGNC:CTSD)
pmid:18930136 path(MESH:"Huntington Disease") positiveCorrelation a(GO:autolysosome)
pmid:29024336 path(MESH:"Huntington Disease") increases path(MESH:"Proteostasis Deficiencies")
pmid:29311797 path(MESH:"Huntington Disease") association p(HGNC:STUB1)
pmid:30046111 path(MESH:"Parkinson Disease") association act(a(MESH:"Lymphatic Vessels"))
pmid:30663117 path(MESH:"Parkinson Disease") association a(HBP:"alpha-synuclein aggregates")
pmid:30663117 path(MESH:"Parkinson Disease") association g(HGNC:MIR132)
pmid:30663117 path(MESH:"Parkinson Disease") association g(NCBIGENE:406950)
pmid:30663117 path(MESH:"Parkinson Disease") association p(HGNC:LRRK2)
pmid:24113872 path(MESH:"Parkinson Disease") positiveCorrelation p(HGNC:LRRK2)
pmid:30663117 path(MESH:"Parkinson Disease") decreases g(HGNC:MIR205)
pmid:30663117 path(MESH:"Parkinson Disease") decreases p(HGNC:PARK7)
pmid:30663117 path(MESH:"Parkinson Disease") increases g(HGNC:MIR494)
pmid:30663117 path(MESH:"Parkinson Disease") decreases g(HGNC:MIR34B)
pmid:30663117 path(MESH:"Parkinson Disease") decreases g(HGNC:MIR34C)
pmid:19126755 path(MESH:"Parkinson Disease") association p(HBP:"alpha-6 alpha-4 beta-2 beta-3 nAChR", loc(MESH:"Basal Ganglia"))
pmid:19126755 path(MESH:"Parkinson Disease") positiveCorrelation path(MESH:Tremor)
pmid:19126755 path(MESH:"Parkinson Disease") positiveCorrelation path(MESH:Hypokinesia)
pmid:19126755 path(MESH:"Parkinson Disease") positiveCorrelation path(MESH:"Muscle Rigidity")
pmid:19126755 path(MESH:"Parkinson Disease") negativeCorrelation path(MESH:"Tobacco Use Disorder")
pmid:17009926 path(MESH:"Parkinson Disease") negativeCorrelation act(p(FPLX:CHRN))
pmid:17009926 path(MESH:"Parkinson Disease") negativeCorrelation p(FPLX:CHRN)
pmid:11230871 path(MESH:"Parkinson Disease") association p(FPLX:CHRN)
pmid:26813123 path(MESH:"Parkinson Disease") negativeCorrelation a(MESH:"Cholinergic Neurons")
pmid:24590577 path(MESH:"Parkinson Disease") association p(HGNC:CHRM4)
pmid:24590577 path(MESH:"Parkinson Disease") decreases act(a(MESH:"Dopaminergic Neurons"))
pmid:21722302 path(MESH:"Parkinson Disease") decreases a(MESH:"Dopaminergic Neurons")
pmid:24762290 path(MESH:"Parkinson Disease") decreases path(MESH:Memory)
pmid:24762290 path(MESH:"Parkinson Disease") association path(MESH:Memory)
pmid:24762290 path(MESH:"Parkinson Disease") association complex(HBP:"alpha-4 beta-2 nAChR")
pmid:28901280 path(MESH:"Parkinson Disease") association p(MESH:"Receptors, Nicotinic")
pmid:22020111 path(MESH:"Parkinson Disease") positiveCorrelation a(HBP:"protein aggregates")
pmid:21722302 path(MESH:"Parkinson Disease") association path(HBP:Neurodegeneration)
pmid:21722302 path(MESH:"Parkinson Disease") association bp(HBP:"protein aggregation")
pmid:21722302 path(MESH:"Parkinson Disease") association p(MESH:"parkin protein")
pmid:21722302 path(MESH:"Parkinson Disease") association bp(GO:"parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization")
pmid:21722302 path(MESH:"Parkinson Disease") association p(HGNC:PARK7, var("?"))
pmid:21722302 path(MESH:"Parkinson Disease") association a(MESH:Paraquat)
pmid:21722302 path(MESH:"Parkinson Disease") decreases bp(GO:"protein quality control for misfolded or incompletely synthesized proteins")
pmid:21722302 path(MESH:"Parkinson Disease") decreases bp(MESH:"Unfolded Protein Response")
pmid:21722302 path(MESH:"Parkinson Disease") increases bp(GO:"neuron death")
pmid:14556719 path(MESH:"Parkinson Disease") positiveCorrelation bp(GO:"neuron death")
pmid:29758300 path(MESH:"Parkinson Disease") positiveCorrelation path(MESH:"Plaque, Amyloid")
pmid:29758300 path(MESH:"Parkinson Disease") association p(HGNC:VPS35, var("?"))
pmid:29758300 path(MESH:"Parkinson Disease") negativeCorrelation bp(GO:macroautophagy)
pmid:14556719 path(MESH:"Parkinson Disease") negativeCorrelation bp(GO:"synaptic transmission, dopaminergic")
pmid:14556719 path(MESH:"Parkinson Disease") negativeCorrelation bp(GO:"proteasome-mediated ubiquitin-dependent protein catabolic process")
pmid:14556719 path(MESH:"Parkinson Disease") positiveCorrelation p(HGNC:PRKN)
pmid:27181519 path(MESH:"Parkinson Disease") association p(HGNC:PRKN)
pmid:14556719 path(MESH:"Parkinson Disease") association p(HGNC:UCHL1, var("?"))
pmid:14556719 path(MESH:"Parkinson Disease") association p(HGNC:UCHL1, var("p.Ile93Met"))
pmid:14556719 path(MESH:"Parkinson Disease") association a(MESH:"Lewy Bodies")
pmid:14556719 path(MESH:"Parkinson Disease") association p(HGNC:SNCA, var("p.Ala30Pro"))
pmid:14556719 path(MESH:"Parkinson Disease") association p(HGNC:SNCA, var("p.Ala53Thr"))
pmid:22908190 path(MESH:"Parkinson Disease") positiveCorrelation p(HGNC:SNCA, pmod(Ub))
pmid:22908190 path(MESH:"Parkinson Disease") association p(HGNC:UCHL1)
pmid:18930136 path(MESH:"Parkinson Disease") positiveCorrelation a(GO:autophagosome)
pmid:28803412 path(MESH:"Parkinson Disease") association p(HGNC:SNCA)
pmid:29980653 path(MESH:"Parkinson Disease") positiveCorrelation p(HGNC:SNCA)
pmid:28803412 path(MESH:"Parkinson Disease") positiveCorrelation a(HBP:HBP00093)
pmid:27075649 path(MESH:"Parkinson Disease") positiveCorrelation a(HBP:HBP00016)
pmid:30116051 path(MESH:"Parkinson Disease") association p(HGNC:PINK1, var("?"))
pmid:30116051 path(MESH:"Parkinson Disease") association p(HGNC:PRKN, var("?"))
pmid:30116051 path(MESH:"Parkinson Disease") association p(HGNC:LRRK2, var("?"))
pmid:29024336 path(MESH:"Parkinson Disease") increases path(MESH:"Proteostasis Deficiencies")
pmid:30985105 path(MESH:"Parkinson Disease") positiveCorrelation deg(a(HBP:"Dopaminergic cell groups"))
pmid:30985105 path(MESH:"Parkinson Disease") association complex(p(HGNC:SNCA), p(HGNC:SNCA))
pmid:30985105 path(MESH:"Parkinson Disease") association act(p(HGNCGENEFAMILY:Calpains))
pmid:30985105 path(MESH:"Parkinson Disease") association act(p(HGNCGENEFAMILY:Calpains))
pmid:29311797 path(MESH:"Parkinson Disease") association p(HGNC:STUB1)
pmid:26751493 path(MESH:"Parkinson Disease") association g(DBSNP:rs2471738)
pmid:26751493 path(MESH:"Parkinson Disease") association g(DBSNP:rs242557)
pmid:26631930 path(MESH:"Parkinson Disease") increases a(CHEBI:"iron(0)")
pmid:29980653 path(MESH:"Parkinson Disease") isA path(MESH:"Neurodegenerative Diseases")
pmid:29980653 path(MESH:"Parkinson Disease") isA path(MESH:"Lewy Body Disease")
pmid:30046111 bp(GO:"excitatory chemical synaptic transmission") association act(a(MESH:"Lymphatic Vessels"))
pmid:19293145 bp(GO:learning) association path(MESH:"Alzheimer Disease")
pmid:24511233 bp(GO:learning) association a(MESH:Hippocampus)
pmid:24511233 bp(GO:learning) association a(MESH:Hippocampus)
pmid:24511233 bp(GO:learning) association a(MESH:"Cerebral Cortex")
pmid:24511233 bp(GO:learning) association a(MESH:"Cerebral Cortex")
pmid:24511233 bp(GO:learning) association bp(GO:"long-term synaptic potentiation")
pmid:24511233 bp(GO:learning) association a(MESH:"Prefrontal Cortex")
pmid:17009926 bp(GO:learning) association p(FPLX:CHRN)
pmid:26813123 bp(GO:learning) association bp(GO:"synaptic transmission, cholinergic")
pmid:26813123 bp(GO:learning) positiveCorrelation bp(GO:"synaptic transmission, cholinergic")
pmid:21482353 bp(GO:learning) association bp(GO:"synaptic transmission, cholinergic")
pmid:26813123 bp(GO:learning) association a(CHEBI:acetylcholine)
pmid:24590577 bp(GO:learning) association p(HGNC:CHRM1)
pmid:19721446 bp(GO:learning) association p(HGNC:CHRNA7)
pmid:30106381 bp(GO:learning) association p(HGNC:ADNP)
pmid:30106381 bp(GO:learning) association a(PUBCHEM:9832404)
pmid:22908190 bp(GO:learning) association bp(GO:"proteasome-mediated ubiquitin-dependent protein catabolic process")
pmid:24355211 bp(GO:learning) negativeCorrelation p(HGNC:GSK3B)
pmid:21843595 bp(GO:learning) negativeCorrelation p(MGI:Sumo3)
pmid:30046111 bp(GO:"neuronal signal transduction") association act(a(MESH:"Lymphatic Vessels"))
pmid:24590577 bp(GO:"neuronal signal transduction") association p(HGNC:CHRM1)
pmid:11230871 bp(GO:"response to oxidative stress") negativeCorrelation p(FPLX:CHRN)
pmid:14556719 bp(GO:"response to oxidative stress") increases p(HGNC:SOD1, pmod(Ub), var("?"))
pmid:14556719 bp(GO:"response to oxidative stress") increases p(HGNC:SOD1, pmod(HBP:misfolding), var("?"))
pmid:23746257 bp(GO:"response to oxidative stress") increases a(MESH:"Heat-Shock Proteins")
pmid:23746257 bp(GO:"response to oxidative stress") association bp(HBP:Proteostasis)
pmid:18930136 bp(GO:"response to oxidative stress") increases p(HGNC:SQSTM1)
pmid:18930136 bp(GO:"response to oxidative stress") increases r(HGNC:SQSTM1)
pmid:24563850 bp(GO:"response to oxidative stress") decreases act(p(HGNC:KEAP1))
pmid:24563850 bp(GO:"response to oxidative stress") increases p(HGNC:NFE2L2)
pmid:24563850 bp(GO:"response to oxidative stress") increases act(p(FPLX:PRDX))
pmid:27671637 bp(GO:"response to oxidative stress") negativeCorrelation p(HBP:"Tau isoform F (441 aa)", var("p.Lys280del"))
pmid:23528736 bp(GO:"response to oxidative stress") increases bp(GO:autophagy)
pmid:22419736 bp(GO:"response to oxidative stress") increases p(HGNC:AK1)
pmid:26751493 bp(GO:"response to oxidative stress") association a(CHEBI:"methylene blue")
pmid:26751493 bp(GO:"response to oxidative stress") association a(CHEBI:"azure A")
pmid:26751493 bp(GO:"response to oxidative stress") association a(CHEBI:"azure B")
pmid:27181519 bp(GO:"response to oxidative stress") increases complex(GO:"cytoplasmic stress granule")
pmid:30126037 bp(GO:"cellular respiration") association act(a(MESH:Mitochondria))
pmid:30046111 bp(GO:"immune response") association bp(GO:aging)
pmid:27288790 bp(GO:"immune response") association m(MIRBASE:"hsa-mir-146a")
pmid:30106381 bp(GO:"immune response") association p(HGNC:ADNP)
pmid:30106381 bp(GO:"immune response") association a(PUBCHEM:9832404)
pmid:23746257 bp(GO:"immune response") association p(FPLX:HSP90)
pmid:30046111 bp(GO:"inflammatory response") association bp(GO:aging)
pmid:29179999 bp(GO:"inflammatory response") association act(p(FPLX:NFkappaB))
pmid:27522251 bp(GO:"inflammatory response") causesNoChange path(MESH:"Memory Disorders")
pmid:23746257 bp(GO:"inflammatory response") association bp(HBP:Proteostasis)
pmid:24563850 bp(GO:"inflammatory response") increases a(CHEBI:"reactive oxygen species")
pmid:16566606 bp(GO:"inflammatory response") increases a(CHEBI:"reactive oxygen species")
pmid:8940412 bp(GO:"inflammatory response") positiveCorrelation act(p(RGD:Crh))
pmid:8940412 bp(GO:"inflammatory response") negativeCorrelation a(CHEBI:antalarmin)
pmid:30126037 bp(GO:"inflammatory response") association bp(GO:"cellular senescence")
pmid:18494933 bp(GO:"inflammatory response") increases p(HGNC:DKK1)
pmid:16566606 bp(GO:"inflammatory response") increases a(CHEBI:"reactive nitrogen species")
pmid:16566606 bp(GO:"inflammatory response") increases a(CHEBI:peroxynitrite)
pmid:30046111 bp(GO:"phospholipid metabolic process") association bp(GO:aging)
pmid:30046111 bp(GO:"extracellular matrix organization") association bp(GO:aging)
pmid:30046111 bp(GO:"cell adhesion") association bp(GO:aging)
pmid:21214928 bp(GO:"cell adhesion") association p(HGNC:APP)
pmid:28901280 bp(GO:"cell adhesion") association a(MESH:Acetylcholine)
pmid:30106381 bp(GO:"cell adhesion") association p(HGNC:ADNP)
pmid:30106381 bp(GO:"cell adhesion") association a(PUBCHEM:9832404)
pmid:30046111 bp(GO:"endothelial tube morphogenesis") association bp(GO:aging)
pmid:10998059 act(p(MGI:Cdk5r1)) increases p(MGI:Ppp1r1b, pmod(Ph))
pmid:19118186 p(MGI:Cdk5r1) increases act(p(MGI:Cdk5))
pmid:27087442 p(MGI:Cdk5r1) decreases bp(GO:"neuron death")
pmid:30046111 p(MGI:Vegfc) increases a(MESH:"Lymphatic Vessels")
pmid:30046111 p(MGI:Vegfc) increases act(a(MESH:"Lymphatic Vessels"))
pmid:30046111 p(MGI:Vegfc) increases a(MESH:"Lymphatic Vessels")
pmid:30046111 p(MGI:Vegfc) increases a(MESH:"Lymphatic Vessels")
pmid:30046111 p(MGI:Vegfc) increases act(a(MESH:"Lymphatic Vessels"))
pmid:30046111 p(MGI:Vegfc) causesNoChange a(MESH:"Lymphatic Vessels")
pmid:30046111 p(MGI:Vegfc) increases path(MESH:"Spatial Learning")
pmid:30046111 p(MGI:Vegfc) increases bp(GO:"stem cell proliferation")
pmid:30046111 p(MGI:Vegfc) increases bp(GO:cognition)
pmid:30046111 p(MGI:Vegfc) increases tloc(a(CHEBI:macromolecule), fromLoc(MESH:"Cerebrospinal Fluid"), toLoc(MESH:"Lymph Nodes"))
pmid:30046111 p(MGI:Vegfc) causesNoChange tloc(a(CHEBI:macromolecule), fromLoc(MESH:"Cerebrospinal Fluid"), toLoc(MESH:"Lymph Nodes"))
pmid:30046111 p(MGI:Vegfc) causesNoChange a(CHEBI:"amyloid-beta")
pmid:30046111 p(MGI:Vegfc) causesNoChange path(HP:"Abnormal lymphatic vessel morphology")
pmid:30046111 composite(a(CHEBI:"poly(ethylene glycol dimethacrylate)"), p(MGI:Vegfc)) increases a(MESH:"Lymphatic Vessels")
pmid:30046111 p(MGI:Vegfc, var("p.Cys156Ser")) increases a(MESH:"Lymphatic Vessels")
pmid:30046111 p(MGI:Vegfc, var("p.Cys156Ser")) increases tloc(a(CHEBI:macromolecule), fromLoc(MESH:"Cerebrospinal Fluid"), toLoc(MESH:Brain))
pmid:30046111 path(MESH:Inflammation) negativeCorrelation act(a(MESH:"Lymphatic Vessels"))
pmid:21329555 path(MESH:Inflammation) positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:27288790 path(MESH:Inflammation) positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:24027553 path(MESH:Inflammation) positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:21329555 path(MESH:Inflammation) association bp(GO:"NIK/NF-kappaB signaling")
pmid:27288790 path(MESH:Inflammation) association p(FPLX:NFkappaB)
pmid:22040696 path(MESH:Inflammation) increases path(MESH:"Renal Insufficiency")
pmid:30106381 path(MESH:Inflammation) association p(HGNC:ADNP)
pmid:30012004 path(MESH:Inflammation) positiveCorrelation path(MESH:"Huntington Disease")
pmid:24027553 path(MESH:Inflammation) increases act(p(HGNCGENEFAMILY:Caspases))
pmid:26195256 path(MESH:Inflammation) increases p(HGNC:MAPT, pmod(HBP:hyperphosphorylation))
pmid:26195256 path(MESH:Inflammation) decreases deg(a(CHEBI:"amyloid-beta"))
pmid:29255009 p(MGI:Fkbp1b) increases path(MESH:Memory)
pmid:29255009 p(MGI:Fkbp1b) increases bp(MESH:Aging)
pmid:29255009 p(MGI:Fkbp1b) increases act(p(MGI:Eif3g))
pmid:29255009 p(MGI:Fkbp1b) increases act(p(MGI:Pla2g7))
pmid:29255009 p(MGI:Fkbp1b) increases act(p(MGI:S100b))
pmid:29255009 p(MGI:Fkbp1b) increases act(p(MGI:Snapc2))
pmid:29255009 p(MGI:Fkbp1b) increases bp(MESH:"Facilitated Diffusion")
pmid:29255009 p(MGI:Fkbp1b) increases bp(GO:"ectoderm development")
pmid:29255009 p(MGI:Fkbp1b) increases bp(GO:"regulation of actin cytoskeleton organization")
pmid:29255009 p(MGI:Fkbp1b) increases act(p(MESH:"Mitogen-Activated Protein Kinases"))
pmid:29255009 p(MGI:Fkbp1b) decreases act(p(MESH:"Membrane Transport Proteins"))
pmid:29255009 p(MGI:Fkbp1b) decreases bp(GO:"blood vessel development")
pmid:29255009 p(MGI:Fkbp1b) decreases bp(GO:"regulation of cellular component movement")
pmid:29255009 p(MGI:Fkbp1b) decreases a(GO:"cytoplasmic vesicle")
pmid:29255009 p(MGI:Fkbp1b) decreases tloc(a(CHEBI:"calcium(2+)"))
pmid:29255009 p(MGI:Fkbp1b) regulates p(MGI:Capn1)
pmid:29255009 p(MGI:Fkbp1b) regulates p(MGI:Ppp3cc)
pmid:29255009 p(MGI:Fkbp1b) decreases p(MGI:Hif1an)
pmid:29255009 p(MGI:Fkbp1b) decreases p(MGI:Nfkb1)
pmid:24762290 path(MESH:Memory) association path(MESH:"Parkinson Disease")
pmid:24762290 path(MESH:Memory) association complex(HBP:"alpha-4 beta-2 nAChR")
pmid:28901280 path(MESH:Memory) association p(MESH:"Receptors, Nicotinic")
pmid:29255009 p(HBP:"AAV-FKBP1B") increases p(MGI:Fkbp1b, loc(MESH:Hippocampus))
pmid:29255009 bp(MESH:Aging) decreases p(MGI:Map2)
pmid:29255009 bp(MESH:Aging) regulates p(MGI:Capn1)
pmid:29255009 bp(MESH:Aging) regulates p(MGI:Ppp3cc)
pmid:24511233 bp(MESH:Aging) association path(MESH:"Alzheimer Disease")
pmid:23528736 bp(MESH:Aging) increases path(MESH:"Alzheimer Disease")
pmid:25437566 bp(MESH:Aging) increases p(HGNC:TPR)
pmid:25437566 bp(MESH:Aging) increases p(HGNC:TPR)
pmid:25437566 bp(MESH:Aging) increases p(HGNC:TPR)
pmid:27491084 bp(MESH:Aging) increases p(HGNC:TPR)
pmid:25437566 bp(MESH:Aging) decreases p(HGNCGENEFAMILY:"DNAJ (HSP40) heat shock proteins")
pmid:25437566 bp(MESH:Aging) decreases p(HGNCGENEFAMILY:"DNAJ (HSP40) heat shock proteins")
pmid:25437566 bp(MESH:Aging) decreases p(HGNCGENEFAMILY:"DNAJ (HSP40) heat shock proteins")
pmid:25437566 bp(MESH:Aging) decreases p(HGNCGENEFAMILY:"DNAJ (HSP40) heat shock proteins")
pmid:27491084 bp(MESH:Aging) decreases p(HGNCGENEFAMILY:"DNAJ (HSP40) heat shock proteins")
pmid:25784053 bp(MESH:Aging) decreases p(HGNCGENEFAMILY:"DNAJ (HSP40) heat shock proteins")
pmid:25437566 bp(MESH:Aging) decreases p(FPLX:HSPA)
pmid:25437566 bp(MESH:Aging) decreases p(FPLX:HSPA)
pmid:27491084 bp(MESH:Aging) decreases p(FPLX:HSPA)
pmid:25784053 bp(MESH:Aging) decreases p(FPLX:HSPA)
pmid:25437566 bp(MESH:Aging) increases p(FPLX:HSPB)
pmid:25437566 bp(MESH:Aging) increases p(FPLX:HSPB)
pmid:27491084 bp(MESH:Aging) increases p(FPLX:HSPB)
pmid:25784053 bp(MESH:Aging) increases p(FPLX:HSPB)
pmid:25437566 bp(MESH:Aging) decreases p(HGNC:HSPD1)
pmid:27491084 bp(MESH:Aging) decreases p(HGNC:HSPD1)
pmid:25437566 bp(MESH:Aging) increases p(HGNC:HSPA2)
pmid:25437566 bp(MESH:Aging) increases p(HGNC:DNAJB2)
pmid:25437566 bp(MESH:Aging) decreases p(HGNC:HSPA12A)
pmid:25437566 bp(MESH:Aging) decreases p(HGNC:TOMM70)
pmid:25437566 bp(MESH:Aging) decreases p(HGNC:HSP90AB1)
pmid:25437566 bp(MESH:Aging) decreases p(HGNC:HSPA8)
pmid:25437566 bp(MESH:Aging) decreases p(HGNC:HSPA14)
pmid:25437566 bp(MESH:Aging) decreases p(HGNC:TCP1)
pmid:25784053 bp(MESH:Aging) regulates bp(HBP:Proteostasis)
pmid:25784053 bp(MESH:Aging) decreases p(FPLX:HSP90)
pmid:29311797 bp(MESH:Aging) increases p(FPLX:HSP90)
pmid:29311797 bp(MESH:Aging) decreases p(FPLX:HSP90)
pmid:29311797 bp(MESH:Aging) decreases p(FPLX:HSP90)
pmid:23528736 bp(MESH:Aging) decreases bp(GO:autophagy)
pmid:23528736 bp(MESH:Aging) decreases bp(GO:"proteasome-mediated ubiquitin-dependent protein catabolic process")
pmid:28420982 bp(MESH:Aging) association tloc(p(HGNC:MAPT), fromLoc(GO:axon), toLoc(GO:"cell body"))
pmid:28420982 bp(MESH:Aging) association tloc(p(HGNC:MAPT), fromLoc(GO:axon), toLoc(GO:dendrite))
pmid:29311797 bp(MESH:Aging) association path(MESH:"Neurodegenerative Diseases")
pmid:29311797 bp(MESH:Aging) decreases bp(GO:"protein folding")
pmid:29311797 bp(MESH:Aging) increases path(MESH:"Protein Aggregation, Pathological")
pmid:29311797 bp(MESH:Aging) decreases bp(MESH:Proteolysis)
pmid:29311797 bp(MESH:Aging) decreases act(p(FPLX:Proteasome))
pmid:29311797 bp(MESH:Aging) decreases act(p(FPLX:Proteasome))
pmid:29311797 bp(MESH:Aging) decreases bp(GO:"chaperone-mediated autophagy")
pmid:29311797 bp(MESH:Aging) decreases bp(GO:"chaperone-mediated autophagy")
pmid:29311797 bp(MESH:Aging) decreases p(HGNC:PPID)
pmid:29311797 bp(MESH:Aging) decreases p(HGNC:PPID)
pmid:29311797 bp(MESH:Aging) increases p(HGNC:FKBP5)
pmid:29311797 bp(MESH:Aging) increases p(HGNC:FKBP5)
pmid:29311797 bp(MESH:Aging) decreases p(HGNC:PPP5C)
pmid:29311797 bp(MESH:Aging) decreases p(HGNC:PPP5C)
pmid:29311797 bp(MESH:Aging) decreases p(HGNC:AHSA1)
pmid:29311797 bp(MESH:Aging) decreases p(HGNC:AHSA1)
pmid:29311797 bp(MESH:Aging) decreases p(HGNC:FKBP4)
pmid:29311797 bp(MESH:Aging) decreases p(HGNC:STIP1)
pmid:29311797 bp(MESH:Aging) decreases p(HGNC:PTGES3)
pmid:29311797 bp(MESH:Aging) increases p(FPLX:HSP90, pmod(Ph))
pmid:29311797 bp(MESH:Aging) increases p(FPLX:HSP90, pmod(Ac))
pmid:29311797 bp(MESH:Aging) increases p(FPLX:HSP90, pmod(NO))
pmid:29311797 bp(MESH:Aging) increases p(FPLX:HSP90, pmod(Ub))
pmid:29255009 p(MGI:Eif3g) increases bp(MESH:Aging)
pmid:29255009 p(MGI:Pla2g7) increases bp(MESH:Aging)
pmid:29255009 p(MGI:S100b) increases bp(MESH:Aging)
pmid:29255009 p(MGI:Snapc2) increases bp(MESH:Aging)
pmid:29255009 path(MESH:Aging) decreases bp(MESH:"Facilitated Diffusion")
pmid:29255009 path(MESH:Aging) decreases bp(GO:"ectoderm development")
pmid:29255009 path(MESH:Aging) decreases bp(GO:"regulation of actin cytoskeleton organization")
pmid:29255009 path(MESH:Aging) decreases act(p(MESH:"Mitogen-Activated Protein Kinases"))
pmid:29255009 path(MESH:Aging) increases act(p(MESH:"Membrane Transport Proteins"))
pmid:29255009 path(MESH:Aging) increases bp(GO:"blood vessel development")
pmid:29255009 path(MESH:Aging) increases bp(GO:"regulation of cellular component movement")
pmid:29255009 path(MESH:Aging) increases a(GO:"cytoplasmic vesicle")
pmid:29255009 path(MESH:Aging) increases p(MGI:Hif1an)
pmid:29255009 path(MESH:Aging) increases p(MGI:Nfkb1)
pmid:19126755 path(MESH:Aging) negativeCorrelation p(HBP:"alpha-4 beta-2 nAChR")
pmid:19126755 path(MESH:Aging) negativeCorrelation p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits")
pmid:19126755 path(MESH:Aging) decreases p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits")
pmid:19126755 path(MESH:Aging) decreases p(MGI:Chrna4)
pmid:19126755 path(MESH:Aging) negativeCorrelation p(MGI:Chrna4)
pmid:19126755 path(MESH:Aging) negativeCorrelation p(MGI:Chrna7)
pmid:26195256 path(MESH:Aging) increases path(MESH:"Alzheimer Disease")
pmid:26195256 path(MESH:Aging) negativeCorrelation a(MESH:"Cerebrospinal Fluid")
pmid:26195256 path(MESH:Aging) negativeCorrelation act(p(HGNC:AQP1))
pmid:19126755 a(CHEBI:"calcium(2+)", loc(GO:intracellular)) increases act(p(FPLX:CREB), ma(tscript))
pmid:19126755 a(CHEBI:"calcium(2+)", loc(GO:intracellular)) increases a(CHEBI:anandamide)
pmid:19126755 a(CHEBI:"calcium(2+)", loc(GO:intracellular)) regulates bp(GO:"signal release")
pmid:19126755 a(CHEBI:"calcium(2+)", loc(GO:intracellular)) regulates bp(MESH:"Neuronal Plasticity")
pmid:19126755 a(CHEBI:"calcium(2+)", loc(GO:intracellular)) regulates bp(GO:"neuron migration")
pmid:22040696 tloc(a(CHEBI:"calcium(2+)"), fromLoc(MESH:"Extracellular Space"), toLoc(MESH:Cytoplasm)) increases bp(GO:"neuron migration")
pmid:19126755 a(CHEBI:"calcium(2+)", loc(GO:intracellular)) regulates bp(GO:"neuron differentiation")
pmid:19293145 a(CHEBI:"calcium(2+)") association act(p(HGNCGENEFAMILY:"Inositol 1,4,5-triphosphate receptors"))
pmid:23038257 a(CHEBI:"calcium(2+)") increases act(p(MESH:"Receptors, Nicotinic"))
pmid:17009926 tloc(a(CHEBI:"calcium(2+)"), fromLoc(MESH:"Extracellular Space"), toLoc(MESH:"Intracellular Space")) increases tloc(a(CHEBI:"calcium(2+)"), fromLoc(MESH:"Intracellular Space"), toLoc(GO:cytosol))
pmid:26472524 tloc(a(CHEBI:"calcium(2+)"), fromLoc(MESH:"Extracellular Space"), toLoc(MESH:"Intracellular Space")) increases bp(GO:"membrane depolarization")
pmid:26472524 a(CHEBI:"calcium(2+)") regulates act(p(FPLX:CHRN))
pmid:26813123 a(CHEBI:"calcium(2+)") regulates p(FPLX:CHRN)
pmid:26813123 a(CHEBI:"calcium(2+)") increases tloc(a(CHEBI:"glutamate(2-)"), fromLoc(GO:intracellular), toLoc(GO:"extracellular region"))
pmid:26813123 a(CHEBI:"calcium(2+)") increases tloc(a(CHEBI:"gamma-aminobutyric acid"), fromLoc(GO:intracellular), toLoc(GO:"extracellular region"))
pmid:26813123 a(CHEBI:"calcium(2+)") increases tloc(a(CHEBI:dopamine), fromLoc(GO:intracellular), toLoc(GO:"extracellular region"))
pmid:26813123 a(CHEBI:"calcium(2+)") increases tloc(a(CHEBI:serotonin), fromLoc(GO:intracellular), toLoc(GO:"extracellular region"))
pmid:26813123 a(CHEBI:"calcium(2+)") increases tloc(a(CHEBI:noradrenaline), fromLoc(GO:intracellular), toLoc(GO:"extracellular region"))
pmid:26813123 a(CHEBI:"calcium(2+)") increases tloc(a(CHEBI:acetylcholine), fromLoc(GO:intracellular), toLoc(GO:"extracellular region"))
pmid:26088141 a(CHEBI:"calcium(2+)") association act(a(MESH:"Calcium Channels"))
pmid:19721446 a(CHEBI:"calcium(2+)") increases act(p(HGNC:CHRNA7))
pmid:19721446 a(CHEBI:"calcium(2+)") increases act(p(HBP:"alpha-4 beta-2 nAChR"))
pmid:24027553 a(CHEBI:"calcium(2+)") increases act(p(HGNCGENEFAMILY:Calpains))
pmid:24027553 a(CHEBI:"calcium(2+)", loc(GO:intracellular)) increases act(p(HGNCGENEFAMILY:Calpains))
pmid:24027553 a(CHEBI:"calcium(2+)", loc(GO:intracellular)) increases act(p(HGNCGENEFAMILY:Calpains))
pmid:2123288 a(CHEBI:"calcium(2+)") increases act(p(FPLX:CALM))
pmid:2833519 a(CHEBI:"calcium(2+)") increases act(p(HGNC:S100B))
pmid:10537045 a(CHEBI:"calcium(2+)") positiveCorrelation complex(p(HGNC:MAPT), p(HGNC:TGM2))
pmid:23702978 a(CHEBI:"calcium(2+)") association p(HGNC:MAP3K7)
pmid:23702978 tloc(a(CHEBI:"calcium(2+)"), fromLoc(MESH:"Extracellular Space"), toLoc(MESH:"Intracellular Space")) increases act(p(HGNC:NLRP3))
pmid:19118186 p(MGI:Capn1) negativeCorrelation p(MGI:Ttbk1)
pmid:29255009 a(CHEBI:sirolimus) decreases bp(HBP:"PI3K-Akt signaling pathway")
pmid:30061532 a(CHEBI:sirolimus) decreases act(p(HGNC:MTOR))
pmid:29758300 a(CHEBI:sirolimus) decreases act(p(HGNC:MTOR))
pmid:18930136 a(CHEBI:sirolimus) decreases act(p(HGNC:MTOR))
pmid:30985105 a(CHEBI:sirolimus) decreases act(p(HGNC:MTOR))
pmid:30061532 a(CHEBI:sirolimus) decreases p(HGNC:MAPT, pmod(HBP:hyperphosphorylation))
pmid:30061532 a(CHEBI:sirolimus) decreases p(HGNC:SNCA, pmod(HBP:misfolded))
pmid:30061532 a(CHEBI:sirolimus) decreases p(HGNC:TARDBP, pmod(HBP:misfolded))
pmid:30061532 a(CHEBI:sirolimus) increases path(MESH:"Interpersonal Relations")
pmid:30061532 a(CHEBI:sirolimus) increases bp(GO:behavior)
pmid:30061532 a(CHEBI:sirolimus) decreases act(a(CHEBI:methamphetamine))
pmid:30061532 a(CHEBI:sirolimus) decreases path(MESH:"Psychotic Disorders")
pmid:30061532 a(CHEBI:sirolimus) decreases path(MESH:"Psychotic Disorders")
pmid:30061532 a(CHEBI:sirolimus) increases bp(GO:autophagy)
pmid:29758300 a(CHEBI:sirolimus) increases bp(GO:autophagy)
pmid:22908190 a(CHEBI:sirolimus) increases bp(GO:autophagy)
pmid:22908190 a(CHEBI:sirolimus) increases bp(GO:autophagy)
pmid:18930136 a(CHEBI:sirolimus) increases bp(GO:autophagy)
pmid:30116051 a(CHEBI:sirolimus) increases bp(GO:autophagy)
pmid:23528736 a(CHEBI:sirolimus) increases bp(GO:autophagy)
pmid:29626319 a(CHEBI:sirolimus) increases bp(GO:autophagy)
pmid:27181519 a(CHEBI:sirolimus) increases bp(GO:autophagy)
pmid:30061532 a(CHEBI:sirolimus) decreases path(MESH:Schizophrenia)
pmid:29758300 a(CHEBI:sirolimus) increases bp(GO:cognition)
pmid:29758300 a(CHEBI:sirolimus) decreases a(CHEBI:"amyloid-beta")
pmid:29758300 a(CHEBI:sirolimus) decreases a(CHEBI:"amyloid-beta")
pmid:22908190 a(CHEBI:sirolimus) decreases a(CHEBI:"amyloid-beta")
pmid:29626319 a(CHEBI:sirolimus) decreases a(CHEBI:"amyloid-beta")
pmid:29758300 a(CHEBI:sirolimus) increases bp(GO:macroautophagy)
pmid:29758300 a(CHEBI:sirolimus) increases bp(GO:macroautophagy)
pmid:26751493 a(CHEBI:sirolimus) increases bp(GO:macroautophagy)
pmid:29758300 a(CHEBI:sirolimus) decreases p(HGNC:MAPT)
pmid:23528736 a(CHEBI:sirolimus) increases deg(p(HGNC:MAPT))
pmid:29758300 a(CHEBI:sirolimus) increases bp(GO:"motor behavior")
pmid:27181519 a(CHEBI:sirolimus) increases bp(GO:"motor behavior")
pmid:22908190 a(CHEBI:sirolimus) decreases path(MESH:Tauopathies)
pmid:22908190 a(CHEBI:sirolimus) decreases path(MESH:Tauopathies)
pmid:25784053 a(CHEBI:sirolimus) decreases act(p(FPLX:mTORC1))
pmid:25784053 a(CHEBI:sirolimus) decreases path(MESH:"Protein Aggregation, Pathological")
pmid:25784053 a(CHEBI:sirolimus) decreases path(MESH:"Huntington Disease")
pmid:18930136 a(CHEBI:sirolimus) decreases path(MESH:"Huntington Disease")
pmid:25784053 a(CHEBI:sirolimus) decreases path(MESH:"Machado-Joseph Disease")
pmid:25784053 a(CHEBI:sirolimus) decreases path(MESH:"Alzheimer Disease")
pmid:25784053 a(CHEBI:sirolimus) decreases path(MESH:"Parkinson Disease")
pmid:25784053 a(CHEBI:sirolimus) decreases path(MESH:"Amyotrophic Lateral Sclerosis")
pmid:18930136 a(CHEBI:sirolimus) decreases path(MESH:"Bulbo-Spinal Atrophy, X-Linked")
pmid:27594586 a(CHEBI:sirolimus) decreases bp(GO:"TOR signaling")
pmid:27594586 a(CHEBI:sirolimus) increases r(HGNC:MMP9)
pmid:27594586 a(CHEBI:sirolimus) increases r(HGNC:MMP2)
pmid:30116051 a(CHEBI:sirolimus) decreases p(HGNC:SNCA)
pmid:27181519 a(CHEBI:sirolimus) increases deg(p(HGNC:SNCA))
pmid:30116051 a(CHEBI:sirolimus) decreases p(HGNC:FUS)
pmid:27181519 a(CHEBI:sirolimus) decreases p(HGNC:FUS, loc(GO:"cytoplasmic stress granule"))
pmid:30116051 a(CHEBI:sirolimus) decreases p(HGNC:HTT)
pmid:27181519 a(CHEBI:sirolimus) increases deg(p(HGNC:HTT))
pmid:24027553 a(CHEBI:sirolimus) increases bp(MESH:Autophagy)
pmid:29626319 a(CHEBI:sirolimus) decreases p(HGNC:MAPT, pmod(Ph))
pmid:27181519 a(CHEBI:sirolimus) increases deg(complex(GO:"cytoplasmic stress granule"))
pmid:27181519 a(CHEBI:sirolimus) increases bp(GO:locomotion)
pmid:27181519 a(CHEBI:sirolimus) increases a(MESH:Neurites)
pmid:27181519 a(CHEBI:sirolimus) decreases bp(GO:"cell death")
pmid:29255009 bp(HBP:"PI3K-Akt signaling pathway") causesNoChange act(p(MGI:Fkbp1b))
pmid:28745240 bp(HBP:"PI3K-Akt signaling pathway") increases act(complex(GO:"NF-kappaB complex"))
pmid:28745240 bp(HBP:"PI3K-Akt signaling pathway") increases act(complex(GO:"NF-kappaB complex"))
pmid:29255009 act(complex(a(CHEBI:sirolimus), p(MGI:Fkbp1b))) decreases bp(HBP:"PI3K-Akt signaling pathway")
pmid:29255009 act(complex(a(CHEBI:sirolimus), p(MGI:Fkbp1a))) decreases bp(HBP:"PI3K-Akt signaling pathway")
pmid:29255009 p(MGI:Fkbp1a) decreases bp(HBP:"PI3K-Akt signaling pathway")
pmid:30126037 act(p(MGI:Nfkb1)) increases bp(MESH:"Cell Survival")
pmid:30126037 act(p(MGI:Nfkb1)) increases bp(GO:"inflammatory response")
pmid:30663117 r(HGNC:BACE1, loc(GO:cytoplasm)) positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:30663117 r(HGNC:BACE1) increases path(MESH:"Alzheimer Disease")
pmid:30663117 r(HGNC:"BACE1-AS") biomarkerFor path(MESH:"Alzheimer Disease")
pmid:30663117 r(HGNC:"BACE1-AS") positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:30663117 r(HGNC:"BACE1-AS") increases r(HGNC:BACE1)
pmid:27288790 r(HGNC:"BACE1-AS") regulates r(HGNC:BACE1)
pmid:27288790 r(HGNC:"BACE1-AS") decreases deg(r(HGNC:BACE1))
pmid:30663117 r(HGNC:"BACE1-AS") increases a(CHEBI:"amyloid-beta")
pmid:30663117 r(HGNC:"BACE1-AS") increases path(MESH:"Plaque, Amyloid")
pmid:27288790 r(HGNC:"BACE1-AS") regulates p(HGNC:BACE1)
pmid:27288790 r(HGNC:"BACE1-AS") increases a(CHEBI:"amyloid-beta polypeptide 42")
pmid:25652642 path(MESH:"Plaque, Amyloid") positiveCorrelation act(complex(GO:"NF-kappaB complex"))
pmid:25652642 path(MESH:"Plaque, Amyloid") association complex(GO:"NF-kappaB complex")
pmid:25652642 path(MESH:"Plaque, Amyloid") association a(MESH:"HLA-DR Antigens")
pmid:29196815 path(MESH:"Plaque, Amyloid") positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:19126755 path(MESH:"Plaque, Amyloid") positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:19293145 path(MESH:"Plaque, Amyloid") positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:19293145 path(MESH:"Plaque, Amyloid") biomarkerFor path(MESH:"Alzheimer Disease")
pmid:19293145 path(MESH:"Plaque, Amyloid") association path(MESH:"Alzheimer Disease")
pmid:24511233 path(MESH:"Plaque, Amyloid") biomarkerFor path(MESH:"Alzheimer Disease")
pmid:24590577 path(MESH:"Plaque, Amyloid") association path(MESH:"Alzheimer Disease")
pmid:25514383 path(MESH:"Plaque, Amyloid") positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:22817713 path(MESH:"Plaque, Amyloid") positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:19293145 path(MESH:"Plaque, Amyloid") association p(HGNC:CHRNA7)
pmid:19293145 path(MESH:"Plaque, Amyloid") causesNoChange r(HGNC:CHRNA4)
pmid:19293145 path(MESH:"Plaque, Amyloid") causesNoChange r(HGNC:CHRNA7)
pmid:24511233 path(MESH:"Plaque, Amyloid") association a(HBP:"amyloid-beta aggregates")
pmid:26195256 path(MESH:"Plaque, Amyloid") association a(HBP:"amyloid-beta aggregates")
pmid:24511233 path(MESH:"Plaque, Amyloid") increases bp(HBP:neuroinflammation)
pmid:24511233 path(MESH:"Plaque, Amyloid") increases bp(GO:"cell death")
pmid:24590577 path(MESH:"Plaque, Amyloid") association bp(GO:"synaptic transmission, cholinergic")
pmid:25514383 path(MESH:"Plaque, Amyloid") association complex(a(CHEBI:"amyloid-beta polypeptide 42"), p(HGNC:CHRNA7))
pmid:29758300 path(MESH:"Plaque, Amyloid") positiveCorrelation path(MESH:"Parkinson Disease")
pmid:14556719 path(MESH:"Plaque, Amyloid") association a(MESH:"Amyloid beta-Peptides")
pmid:24027553 path(MESH:"Plaque, Amyloid") association p(HGNC:MAP1LC3A)
pmid:28420982 path(MESH:"Plaque, Amyloid") association a(MESH:Exosomes)
pmid:26195256 path(MESH:"Plaque, Amyloid") negativeCorrelation act(p(HGNC:MMP2))
pmid:26195256 path(MESH:"Plaque, Amyloid") increases act(a(MESH:Astrocytes))
pmid:18562203 path(MESH:"Plaque, Amyloid") association act(a(MESH:Astrocytes))
pmid:23531502 path(MESH:"Plaque, Amyloid") association act(a(CHEBI:acrolein))
pmid:18562203 path(MESH:"Plaque, Amyloid") positiveCorrelation p(HGNC:MAPT, pmod(HBP:nitration, Tyr, 18))
pmid:26400044 path(MESH:"Plaque, Amyloid") association complex(p(MGI:Dpysl2, pmod(Ph)), p(MGI:Mapt, pmod(Ph)), p(MGI:Wasf1, pmod(Ph)))
pmid:23088643 path(MESH:"Plaque, Amyloid") association p(HBP:"Tau epitope, AT8")
pmid:28877763 path(MESH:"Plaque, Amyloid") association a(HBP:"dystrophic neurite")
pmid:24401760 path(MESH:"Plaque, Amyloid") association a(HBP:"dystrophic neurite")
pmid:28877763 path(MESH:"Plaque, Amyloid") positiveCorrelation p(HGNC:SYK, pmod(Ph))
pmid:24401760 path(MESH:"Plaque, Amyloid") positiveCorrelation p(HGNC:ITPKB)
pmid:30663117 g(HGNC:"MIR124-1") decreases p(HGNC:BACE1)
pmid:21329555 p(HGNC:BACE1) positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:10656250 p(HGNC:BACE1) increases sec(a(HBP:"sAPP-beta"))
pmid:24590577 p(HGNC:BACE1) increases a(HBP:"sAPP-beta")
pmid:10656250 p(HGNC:BACE1) causesNoChange sec(a(HBP:"sAPP-alpha"))
pmid:10656250 p(HGNC:BACE1) causesNoChange p(HGNC:APP)
pmid:10656250 p(HGNC:BACE1, loc(GO:"endoplasmic reticulum")) association p(HGNC:APP, loc(GO:"endoplasmic reticulum"))
pmid:24590577 p(HGNC:BACE1) increases deg(p(HGNC:APP))
pmid:21718217 p(HGNC:BACE1) decreases p(HGNC:APP)
pmid:10656250 p(HGNC:BACE1) increases p(HGNC:APP, frag("672_770"))
pmid:10656250 p(HGNC:BACE1) association a(HBP:APP695)
pmid:10656250 p(HGNC:BACE1) association a(HBP:APP751)
pmid:30444369 p(HGNC:BACE1) increases rxn(reactants(p(HGNC:APP)), products(a(CHEBI:"amyloid-beta polypeptide 42"), p(HBP:"APP C-terminally truncated carboxyl-terminal fragments")))
pmid:18650430 act(p(HGNC:BACE1), ma(pep)) increases rxn(reactants(p(HGNC:APP)), products(p(HGNC:APP, frag("11_*")), p(HGNC:APP, frag("1_10"))))
pmid:21214928 p(HGNC:BACE1) increases rxn(reactants(p(HGNC:APP)), products(a(CHEBI:"amyloid-beta")))
pmid:21214928 p(HGNC:BACE1) increases rxn(reactants(p(HGNC:APP)), products(a(CHEBI:"amyloid-beta")))
pmid:21214928 p(HGNC:BACE1) increases rxn(reactants(p(HGNC:APP)), products(a(CHEBI:"amyloid-beta")))
pmid:22122372 p(HGNC:BACE1) increases rxn(reactants(p(HGNC:APP)), products(a(CHEBI:"amyloid-beta")))
pmid:21722302 p(HGNC:BACE1) increases rxn(reactants(p(HGNC:APP)), products(a(CHEBI:"amyloid-beta")))
pmid:21214928 p(HGNC:BACE1) increases bp(GO:"neuron death")
pmid:21214928 p(HGNC:BACE1) decreases bp(GO:"synaptic transmission, cholinergic")
pmid:21214928 p(HGNC:BACE1) decreases bp(GO:memory)
pmid:21214928 p(HGNC:BACE1) increases p(HGNC:APP, frag("672_713"))
pmid:21214928 p(HGNC:BACE1) increases p(HGNC:APP, frag("672_711"))
pmid:22122372 p(HGNC:BACE1) increases rxn(reactants(p(HGNC:APP)), products(a(HBP:HBP00042), a(HBP:HBP00081)))
pmid:22122372 p(HGNC:BACE1) increases rxn(reactants(p(HGNC:APP)), products(a(HBP:HBP00042), a(HBP:HBP00081)))
pmid:22122372 p(HGNC:BACE1) increases a(CHEBI:"amyloid-beta")
pmid:18986241 act(p(HGNC:BACE1)) increases a(CHEBI:"amyloid-beta")
pmid:25331948 p(HGNC:BACE1) increases a(CHEBI:"amyloid-beta")
pmid:26195256 act(p(HGNC:BACE1)) increases a(CHEBI:"amyloid-beta")
pmid:29626319 p(HGNC:BACE1) increases a(CHEBI:"amyloid-beta")
pmid:19126755 p(HGNC:BACE1) increases a(CHEBI:"amyloid-beta polypeptide 42")
pmid:24590577 p(HGNC:BACE1) increases a(HBP:C99)
pmid:21718217 p(HGNC:BACE1) increases a(CHEBI:"amyloid-beta polypeptide 40")
pmid:29758300 p(HGNC:BACE1) increases p(HGNC:APP, frag("?"))
pmid:14556719 p(HGNC:BACE1) increases rxn(reactants(p(HGNC:APP)), products(a(CHEBI:"amyloid-beta polypeptide 40"), a(CHEBI:"amyloid-beta polypeptide 42")))
pmid:30663117 complex(g(HGNC:"MIR124-1"), r(HGNC:BACE1)) decreases act(r(HGNC:BACE1))
pmid:30663117 complex(g(HGNC:MIR15B), r(HGNC:BACE1)) decreases p(HGNC:BACE1)
pmid:30663117 complex(g(HGNC:MIR339), r(HGNC:BACE1)) decreases p(HGNC:BACE1)
pmid:30663117 complex(g(HGNC:MIR384), r(HGNC:BACE1)) decreases p(HGNC:BACE1)
pmid:30663117 g(HGNC:MIR384) association path(MESH:"Alzheimer Disease")
pmid:30663117 complex(g(HGNC:MIR384), r(HGNC:APP)) decreases p(HGNC:APP)
pmid:30232325 p(HGNC:APP) increases act(p(HGNC:WNT3A))
pmid:30232325 p(HGNC:APP) increases act(p(HGNC:WNT5A))
pmid:30232325 p(HGNC:APP) increases bp(GO:"canonical Wnt signaling pathway")
pmid:30232325 p(HGNC:APP) increases bp(GO:"non-canonical Wnt signaling pathway")
pmid:11230871 act(p(HGNC:APP)) association p(HGNC:APP, var("p.Lys670Asn"), var("p.Met671Leu"))
pmid:30232325 p(HGNC:APP) increases act(p(HGNC:DKK1))
pmid:30232325 p(HGNC:APP) increases act(p(HGNC:DKK1))
pmid:30232325 p(HGNC:APP) increases bp(HBP:HBP00061)
pmid:10656250 p(HGNC:APP, loc(GO:"endoplasmic reticulum")) association p(HGNC:BACE1, loc(GO:"endoplasmic reticulum"))
pmid:18650430 p(HGNC:APP) increases bp(GO:"regulation of cell growth")
pmid:18650430 p(HGNC:APP) increases bp(GO:"synapse assembly")
pmid:21214928 p(HGNC:APP) association bp(GO:"synapse assembly")
pmid:18650430 p(HGNC:APP) increases bp(MESH:"Neuronal Outgrowth")
pmid:21214928 p(HGNC:APP) association bp(MESH:"Neuronal Outgrowth")
pmid:18650430 p(HGNC:APP) increases bp(GO:"cell adhesion")
pmid:21214928 p(HGNC:APP) association bp(GO:"cell adhesion")
pmid:22122372 p(HGNC:APP) increases bp(GO:"cell adhesion")
pmid:18650430 p(HGNC:APP) regulates act(p(HGNC:SLC5A7))
pmid:21214928 p(HGNC:APP) increases a(CHEBI:"amyloid-beta")
pmid:22122372 p(HGNC:APP) increases a(CHEBI:"amyloid-beta")
pmid:21722302 p(HGNC:APP) increases a(CHEBI:"amyloid-beta")
pmid:18930136 deg(p(HGNC:APP)) association a(CHEBI:"amyloid-beta")
pmid:21214928 p(HGNC:APP) association bp(GO:"signal transduction")
pmid:21214928 p(HGNC:APP) association bp(GO:"calcium ion homeostasis")
pmid:21214928 p(HGNC:APP) association bp(GO:"protein transport")
pmid:21214928 p(HGNC:APP) regulates bp(GO:"protein transport")
pmid:21214928 p(HGNC:APP) association p(HGNC:ITGB1)
pmid:21214928 p(HGNC:APP) association bp(GO:"anterograde axonal protein transport")
pmid:22122372 p(HGNC:APP) increases a(MESH:"Amyloid beta-Peptides")
pmid:29758300 p(HGNC:APP) increases a(MESH:"Amyloid beta-Peptides")
pmid:14556719 p(HGNC:APP) increases a(MESH:"Amyloid beta-Peptides")
pmid:22122372 p(HGNC:APP) association a(HBP:HBP00078)
pmid:22122372 p(HGNC:APP) association a(HBP:HBP00079)
pmid:22122372 p(HGNC:APP) association a(MESH:"Receptors, Cell Surface")
pmid:12428809 p(HGNC:APP) association bp(GO:"axonal transport")
pmid:12428809 sec(p(HGNC:APP)) association bp(GO:"regulation of neuronal synaptic plasticity")
pmid:12428809 sec(p(HGNC:APP)) association bp(GO:"negative regulation of neuron apoptotic process")
pmid:22908190 p(HGNC:APP) positiveCorrelation p(HBP:"APP C-terminally truncated carboxyl-terminal fragments")
pmid:22908190 p(HGNC:APP) positiveCorrelation bp(GO:endocytosis)
pmid:22908190 p(HGNC:APP) increases a(GO:endosome)
pmid:22908190 p(HGNC:APP) association a(GO:autophagosome)
pmid:26631930 surf(p(HGNC:APP)) increases complex(p(HGNC:APP), p(HGNC:SLC40A1))
pmid:30663117 complex(g(HGNC:"MIR153-1"), r(HGNC:BACE1)) decreases p(HGNC:APP)
pmid:30663117 g(HGNC:"MIR153-1") decreases p(HGNC:APP)
pmid:30663117 g(HGNC:"MIR153-1") decreases a(CHEBI:"amyloid-beta")
pmid:30663117 g(HGNC:"MIR153-1") association path(MESH:"Alzheimer Disease")
pmid:30663117 g(HGNC:"MIR153-1") regulates p(HGNC:SNCA)
pmid:30663117 g(HGNC:"MIR153-1") regulates p(HGNC:SNCA)
pmid:30663117 g(HGNC:"MIR153-1") decreases path(MESH:"Parkinson Disease")
pmid:30663117 p(HGNC:RANBP9) increases p(HGNC:APP)
pmid:30663117 g(HGNC:"MIR101-1") decreases p(HGNC:APP)
pmid:30663117 g(HGNC:"MIR101-1") decreases act(p(HGNC:APP))
pmid:30663117 g(HGNC:"MIR101-1") decreases act(p(HGNC:RANBP9))
pmid:30663117 g(HGNC:"MIR101-1") association path(MESH:"Alzheimer Disease")
pmid:30663117 g(HGNC:"MIR101-1") decreases path(MESH:"Alzheimer Disease")
pmid:30663117 act(p(HGNC:CAMKK2), ma(kin)) increases p(HGNC:MAPT, pmod(Ph))
pmid:30663117 act(p(HGNC:CAMKK2), ma(kin)) increases p(HGNC:MAPT, pmod(Ph))
pmid:30663117 p(HGNC:CAMKK2) increases act(a(CHEBI:"amyloid-beta"))
pmid:30116051 p(HGNC:CAMKK2) increases act(p(HGNC:PSMC5))
pmid:30663117 p(HGNC:MAPT, pmod(Ph)) increases a(GO:"neurofibrillary tangle")
pmid:21214928 p(HGNC:MAPT, pmod(Ph)) increases a(GO:"neurofibrillary tangle")
pmid:28420982 p(HGNC:MAPT, pmod(Ph)) increases a(GO:"neurofibrillary tangle")
pmid:22122372 p(HGNC:MAPT, pmod(Ph)) association bp(GO:"neurofibrillary tangle assembly")
pmid:19293145 p(HGNC:MAPT, pmod(Ph)) association p(HGNC:FYN)
pmid:24653673 p(HGNC:MAPT, pmod(Ph)) association p(FPLX:PPP2, pmod(Me, Tyr, 307))
pmid:24653673 p(HGNC:MAPT, pmod(Ph)) decreases complex(a(GO:"protein phosphatase type 2A complex"), p(HGNC:MAPT))
pmid:24653673 p(HGNC:MAPT, pmod(Ph)) positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:29758300 p(HGNC:MAPT, pmod(Ph)) increases path(MESH:"Alzheimer Disease")
pmid:8282104 p(HGNC:MAPT, pmod(Ph)) positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:29191965 p(HGNC:MAPT, pmod(Ph)) positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:29191965 p(HGNC:MAPT, pmod(Ph)) positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:29311797 p(HGNC:MAPT, pmod(Ph)) association path(MESH:"Alzheimer Disease")
pmid:26458742 p(HGNC:MAPT, pmod(Ph)) positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:26631930 p(HGNC:MAPT, pmod(Ph)) positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:26631930 p(HGNC:MAPT, pmod(Ph)) positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:24653673 p(HGNC:MAPT, pmod(Ph)) positiveCorrelation a(CHEBI:homocysteine)
pmid:24653673 p(HGNC:MAPT, pmod(Ph)) negativeCorrelation p(FPLX:PPP2, pmod(Me))
pmid:29758300 p(HGNC:MAPT, pmod(Ph)) decreases act(complex(GO:"proteasome complex"))
pmid:29758300 p(HGNC:MAPT, pmod(Ph)) association complex(GO:"proteasome complex")
pmid:29758300 p(HGNC:MAPT, pmod(Ph)) association bp(GO:autophagy)
pmid:29758300 p(HGNC:MAPT, pmod(Ph)) positiveCorrelation p(HGNC:MTOR)
pmid:29758300 deg(p(HGNC:MAPT, pmod(Ph))) decreases bp(GO:"neuron death")
pmid:29758300 deg(p(HGNC:MAPT, pmod(Ph))) decreases path(HBP:neuroinflammation)
pmid:29758300 deg(p(HGNC:MAPT, pmod(Ph))) increases bp(GO:cognition)
pmid:29758300 p(HGNC:MAPT, pmod(Ph)) positiveCorrelation p(HGNC:TREM2)
pmid:29758300 p(HGNC:MAPT, pmod(Ph)) positiveCorrelation p(HGNC:MAPT, var("p.Ala152Thr"))
pmid:24027553 p(HGNC:MAPT, pmod(Ph)) association path(MESH:"Neurofibrillary Tangles")
pmid:24027553 p(HGNC:MAPT, pmod(Ph)) decreases act(a(CHEBI:Thrombin))
pmid:17403556 p(HGNC:MAPT, pmod(Ph)) positiveCorrelation path(HBP:Neurodegeneration)
pmid:22611162 p(HGNC:MAPT, pmod(Ph)) positiveCorrelation p(HGNC:MAPT, var("p.Lys280del"))
pmid:24760868 p(HGNC:MAPT, pmod(Ph)) association act(p(HGNC:MAPT))
pmid:26195256 p(HGNC:MAPT, pmod(Ph)) decreases deg(p(HGNC:MAPT))
pmid:21882945 p(HGNC:MAPT, pmod(Ph)) regulates complex(a(GO:microtubule), p(HGNC:MAPT))
pmid:21882945 p(HGNC:MAPT, pmod(Ph)) decreases complex(a(GO:microtubule), p(HGNC:MAPT))
pmid:30985105 p(HGNC:MAPT, pmod(Ph)) decreases complex(a(GO:microtubule), p(HGNC:MAPT))
pmid:26631930 p(HGNC:MAPT, pmod(Ph)) decreases complex(a(GO:microtubule), p(HGNC:MAPT))
pmid:21882945 deg(p(HGNC:MAPT, pmod(Ph))) association p(HGNC:BAG2)
pmid:22419736 p(HGNC:MAPT, pmod(Ph)) negativeCorrelation act(p(FPLX:AMPK))
pmid:22419736 p(HGNC:MAPT, pmod(Ph)) negativeCorrelation p(FPLX:AMPK)
pmid:22419736 p(HGNC:MAPT, pmod(Ph)) association path(MESH:"Retinal Degeneration")
pmid:29191965 p(HGNC:MAPT, pmod(Ph)) positiveCorrelation a(HBP:"Tau aggregates")
pmid:26631930 p(HGNC:MAPT, pmod(Ph)) increases a(HBP:"Tau aggregates")
pmid:26631930 p(HGNC:MAPT, pmod(Ph)) increases a(HBP:"Tau aggregates")
pmid:22817713 p(HGNC:MAPT, pmod(Ph)) increases a(HBP:"Tau aggregates")
pmid:28420982 p(HGNC:MAPT, pmod(Ph)) increases a(HBP:"Tau oligomers")
pmid:28420982 p(HGNC:MAPT, pmod(Ph)) increases a(HBP:"Tau oligomers")
pmid:26631930 p(HGNC:MAPT, pmod(Ph)) decreases complex(a(MESH:Actins), p(HGNC:MAPT))
pmid:27260836 p(HGNC:MAPT, pmod(Ph)) partOf complex(GO:"neurofibrillary tangle")
pmid:27260836 p(HGNC:MAPT, pmod(Ph)) partOf complex(GO:"neurofibrillary tangle")
pmid:27260836 p(HGNC:MAPT, pmod(Ph)) association p(HGNC:PICALM)
pmid:27260836 p(HGNC:MAPT, pmod(Ph)) association p(HGNC:PICALM)
pmid:27260836 p(HGNC:MAPT, pmod(Ph)) partOf complex(GO:"Pick body")
pmid:27260836 p(HGNC:MAPT, pmod(Ph)) partOf complex(GO:"Cajal body")
pmid:18467332 p(HGNC:MAPT, pmod(Ph)) decreases complex(p(HGNC:MAPT), p(HGNC:SRC))
pmid:18467332 p(HGNC:MAPT, pmod(Ph)) decreases complex(p(HGNC:MAPT), p(HGNC:PLCG1))
pmid:18467332 p(HGNC:MAPT, pmod(Ph)) decreases complex(p(HGNC:GRB2), p(HGNC:MAPT))
pmid:18467332 p(HGNC:MAPT, pmod(Ph)) decreases complex(p(HGNC:MAPT), p(HGNC:PIK3R1))
pmid:10464280 p(HGNC:MAPT, pmod(Ph)) negativeCorrelation rxn(reactants(p(HGNC:MAPT, pmod(Ph))), products(a(CHEBI:"phosphate(3-)"), p(HGNC:MAPT)))
pmid:19363271 p(HGNC:MAPT, pmod(Ph)) positiveCorrelation p(FPLX:HSP90)
pmid:14963027 p(HGNC:MAPT, pmod(Ph)) association p(HGNC:HSPB1)
pmid:14963027 p(HGNC:MAPT, pmod(Ph)) increases complex(p(HGNC:HSPB1), p(HGNC:MAPT, pmod(Ph)))
pmid:14963027 act(p(HGNC:MAPT, pmod(Ph))) increases bp(GO:"neuron apoptotic process")
pmid:14612456 p(HGNC:MAPT, pmod(Ph)) positiveCorrelation p(HGNC:MAPT, pmod(Ub))
pmid:14612456 p(HGNC:MAPT, pmod(Ph)) isA complex(p(HGNC:MAPT, pmod(Ph)), p(HGNC:STUB1), p(HGNC:UBE2D2))
pmid:17954934 p(HGNC:MAPT, pmod(Ph)) negativeCorrelation p(HGNC:BAG1)
pmid:23943618 p(HGNC:MAPT, pmod(Ph)) negativeCorrelation complex(p(FPLX:PPP2), p(HGNC:MAPT))
pmid:16630055 p(HGNC:MAPT, pmod(Ph)) negativeCorrelation p(HGNC:MAPT, pmod(HBP:"O-GlcNAcylation"))
pmid:20869593 p(HGNC:MAPT, pmod(Ph)) positiveCorrelation p(HGNC:MAPT, pmod(Ac))
pmid:19401603 p(HGNC:MAPT, pmod(Ph)) positiveCorrelation complex(a(MESH:Microtubules), p(HGNC:MAPT, pmod(Ph)))
pmid:24760868 act(p(HGNC:MAPT)) association p(HGNC:MAPT, pmod(Ph))
pmid:26195256 p(HGNC:MAPT, loc(MESH:"Neurofibrillary Tangles")) positiveCorrelation p(HGNC:MAPT, pmod(HBP:hyperphosphorylation), loc(MESH:"Cerebrospinal Fluid"))
pmid:19293145 p(HGNC:MAPT) association a(MESH:"Neurofibrillary Tangles")
pmid:14556719 p(HGNC:MAPT) association a(MESH:"Neurofibrillary Tangles")
pmid:14556719 deg(p(HGNC:MAPT)) increases a(MESH:"Neurofibrillary Tangles")
pmid:27574109 p(HGNC:MAPT) association a(MESH:"Neurofibrillary Tangles")
pmid:26813123 act(p(HGNC:MAPT)) association act(p(HGNC:CHRM1))
pmid:24590577 p(HGNC:MAPT) regulates bp(GO:"microtubule anchoring")
pmid:24590577 p(HGNC:MAPT) regulates bp(GO:"axonal transport")
pmid:12428809 p(HGNC:MAPT) association bp(GO:"axonal transport")
pmid:12428809 p(HGNC:MAPT) increases bp(GO:"axonal transport")
pmid:21734277 tloc(p(HGNC:MAPT)) causesNoChange bp(GO:"axonal transport")
pmid:28420982 p(HGNC:MAPT) regulates bp(GO:"axonal transport")
pmid:26631930 p(HGNC:MAPT) regulates bp(GO:"axonal transport")
pmid:25514383 p(HGNC:MAPT) positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:29758300 p(HGNC:MAPT) association path(MESH:"Alzheimer Disease")
pmid:14556719 p(HGNC:MAPT) association path(MESH:"Alzheimer Disease")
pmid:24027553 p(HGNC:MAPT) association path(MESH:"Alzheimer Disease")
pmid:24027553 p(HGNC:MAPT) positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:27574109 p(HGNC:MAPT) positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:27574109 p(HGNC:MAPT) positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:30126037 p(HGNC:MAPT) association path(MESH:"Alzheimer Disease")
pmid:28420982 p(HGNC:MAPT) positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:28420982 p(HGNC:MAPT) positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:26631930 p(HGNC:MAPT) positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:29238289 p(HGNC:MAPT) biomarkerFor path(MESH:"Alzheimer Disease")
pmid:29980653 p(HGNC:MAPT) positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:26837465 p(HGNC:MAPT) decreases act(p(HGNC:ESR1), ma(tscript))
pmid:10391244 act(p(HGNC:MAPT)) negativeCorrelation p(HGNC:MAPT, pmod(Ph, Thr, 231))
pmid:19277525 p(HGNC:MAPT) increases complex(p(HGNC:MAPT), p(INTERPRO:"Protein phosphatase 2A regulatory subunit PR55"))
pmid:12428809 p(HGNC:MAPT) increases bp(GO:"microtubule cytoskeleton organization")
pmid:12428809 p(HGNC:MAPT) decreases bp(GO:"microtubule depolymerization")
pmid:12428809 p(HGNC:MAPT) increases bp(GO:"axon development")
pmid:29758300 p(HGNC:MAPT) increases complex(a(GO:cytoskeleton), a(GO:microtubule))
pmid:29758300 p(HGNC:MAPT) increases bp(GO:"anterograde axonal protein transport")
pmid:27373205 p(HGNC:MAPT) causesNoChange bp(GO:"anterograde axonal protein transport")
pmid:29758300 p(HGNC:MAPT) increases bp(GO:"retrograde axonal protein transport")
pmid:27373205 p(HGNC:MAPT) causesNoChange bp(GO:"retrograde axonal protein transport")
pmid:29758300 p(HGNC:MAPT) association path(MESH:Tauopathies)
pmid:29980653 p(HGNC:MAPT) positiveCorrelation path(MESH:Tauopathies)
pmid:29758300 p(HGNC:MAPT) association path(MESH:"Frontotemporal Dementia")
pmid:28420982 p(HGNC:MAPT) positiveCorrelation path(MESH:"Frontotemporal Dementia")
pmid:29758300 p(HGNC:MAPT) association path(MESH:"Niemann-Pick Diseases")
pmid:29758300 p(HGNC:MAPT) association path(MESH:"Supranuclear Palsy, Progressive")
pmid:30126037 p(HGNC:MAPT) association path(MESH:"Supranuclear Palsy, Progressive")
pmid:29758300 p(HGNC:MAPT) association p(HGNC:NBR1)
pmid:29758300 p(HGNC:MAPT) positiveCorrelation p(HGNC:TREM2)
pmid:14556719 p(HGNC:MAPT) association a(GO:microtubule)
pmid:25374103 p(HGNC:MAPT) regulates act(a(GO:microtubule))
pmid:28420982 p(HGNC:MAPT) increases a(GO:microtubule)
pmid:26631930 tloc(p(HGNC:MAPT), fromLoc(GO:axon), toLoc(MESH:"Dendritic Spines")) negativeCorrelation a(GO:microtubule)
pmid:29626319 p(HGNC:MAPT) increases a(GO:microtubule)
pmid:22908190 p(HGNC:MAPT) association a(HBP:"paired helical filaments")
pmid:22908190 p(HGNC:MAPT) association a(HBP:"paired helical filaments")
pmid:22908190 p(HGNC:MAPT) association a(GO:"Lewy body")
pmid:22908190 p(HGNC:MAPT) association a(GO:"Pick body")
pmid:27574109 p(HGNC:MAPT) association a(GO:"Pick body")
pmid:22908190 p(HGNC:MAPT) negativeCorrelation act(complex(GO:"proteasome complex"))
pmid:26751493 p(HGNC:MAPT) negativeCorrelation act(complex(GO:"proteasome complex"))
pmid:22908190 deg(p(HGNC:MAPT)) increases p(HGNC:MAPT, frag("?"))
pmid:30145931 p(HGNC:MAPT) increases p(HGNC:SQSTM1)
pmid:30145931 p(HGNC:MAPT, loc(MESH:Dendrites)) decreases a(MESH:"Dendritic Spines")
pmid:30116051 p(HGNC:MAPT) decreases bp(GO:"proteasome-mediated ubiquitin-dependent protein catabolic process")
pmid:23528736 deg(p(HGNC:MAPT)) association bp(GO:"proteasome-mediated ubiquitin-dependent protein catabolic process")
pmid:29215007 p(HGNC:MAPT) increases bp(GO:"actin filament bundle assembly")
pmid:29215007 p(HGNC:MAPT) increases bp(GO:"actin filament bundle assembly")
pmid:24027553 p(HGNC:MAPT) negativeCorrelation act(a(MESH:Neurons))
pmid:26631930 p(HGNC:MAPT) regulates act(a(MESH:Neurons))
pmid:26631930 p(HGNC:MAPT) increases a(MESH:Neurons)
pmid:26631930 p(HGNC:MAPT) increases act(a(MESH:Neurons))
pmid:29238289 p(HGNC:MAPT, loc(GO:"extracellular region")) increases act(a(MESH:Neurons))
pmid:29238289 sec(p(HGNC:MAPT)) increases act(a(MESH:Neurons))
pmid:27574109 p(HGNC:MAPT) association a(HBP:pretangles)
pmid:27574109 p(HGNC:MAPT) association a(HBP:"Braak_Stage I")
pmid:27574109 p(HGNC:MAPT) association a(HBP:"Braak_Stage II")
pmid:27574109 p(HGNC:MAPT) association a(HBP:"Corticobasal Degeneration")
pmid:27574109 p(HGNC:MAPT) positiveCorrelation a(HBP:"Corticobasal Degeneration")
pmid:27574109 p(HGNC:MAPT) positiveCorrelation a(HBP:"Corticobasal Degeneration")
pmid:27574109 p(HGNC:MAPT) positiveCorrelation path(MESH:"Pick Disease of the Brain")
pmid:27574109 p(HGNC:MAPT) positiveCorrelation path(MESH:"Pick Disease of the Brain")
pmid:29590627 p(HGNC:MAPT) increases tloc(p(HGNC:MAPT), fromLoc(GO:"extracellular region"), toLoc(MESH:Neurons))
pmid:26195256 p(HGNC:MAPT, loc(MESH:"Neurofibrillary Tangles")) positiveCorrelation p(HGNC:MAPT, loc(MESH:"Cerebrospinal Fluid"))
pmid:26195256 p(HGNC:MAPT, loc(MESH:"Cerebrospinal Fluid")) positiveCorrelation p(HGNC:MAPT, loc(MESH:"Neurofibrillary Tangles"))
pmid:26631930 p(HGNC:MAPT) positiveCorrelation tloc(p(HGNC:MAPT), fromLoc(GO:axon), toLoc(MESH:"Dendritic Spines"))
pmid:26631930 tloc(p(HGNC:MAPT), fromLoc(GO:axon), toLoc(MESH:"Dendritic Spines")) positiveCorrelation p(HGNC:MAPT)
pmid:24760868 p(HGNC:MAPT) positiveCorrelation bp(GO:"long-term synaptic potentiation")
pmid:24760868 tloc(p(HGNC:MAPT), fromLoc(GO:"dendritic shaft"), toLoc(GO:synapse)) positiveCorrelation bp(GO:"long-term synaptic potentiation")
pmid:24760868 p(HGNC:MAPT) positiveCorrelation bp(GO:"long-term synaptic potentiation")
pmid:24760868 tloc(p(HGNC:MAPT), fromLoc(GO:"dendritic shaft"), toLoc(GO:synapse)) association bp(MESH:"Neuronal Plasticity")
pmid:24760868 p(HGNC:MAPT) regulates bp(MESH:"Neuronal Plasticity")
pmid:24760868 p(HGNC:MAPT) increases complex(complex(GO:"filamentous actin"), p(HGNC:MAPT))
pmid:17187063 p(HGNC:MAPT) increases complex(complex(GO:"filamentous actin"), p(HGNC:MAPT))
pmid:24760868 p(HGNC:MAPT) increases complex(complex(GO:"actin filament bundle"), p(HGNC:MAPT))
pmid:24760868 p(HGNC:MAPT) association complex(GO:"filamentous actin")
pmid:17187063 p(HGNC:MAPT) directlyIncreases complex(GO:"filamentous actin")
pmid:24760868 p(HGNC:MAPT, loc(GO:synapse)) increases complex(a(GO:"filamentous actin"), p(HGNC:MAPT))
pmid:28528849 p(HGNC:MAPT) causesNoChange a(GO:synapse)
pmid:26631930 tloc(p(HGNC:MAPT), fromLoc(GO:axon), toLoc(GO:"somatodendritic compartment")) decreases act(a(GO:synapse))
pmid:26631930 tloc(p(HGNC:MAPT), fromLoc(GO:axon), toLoc(MESH:"Dendritic Spines")) decreases act(a(GO:synapse))
pmid:26631930 p(HGNC:MAPT) negativeCorrelation act(a(GO:synapse))
pmid:25887395 p(HGNC:MAPT) causesNoChange tloc(a(HBP:"Tau fibrils"), fromLoc(MESH:"Extracellular Space"), toLoc(MESH:"Intracellular Space"))
pmid:29980653 tloc(p(HGNC:MAPT), fromLoc(GO:"extracellular region"), toLoc(GO:intracellular)) increases a(HBP:"Tau fibrils")
pmid:24869773 p(HGNC:MAPT) association a(HBP:"Tau fibrils")
pmid:25887395 p(HGNC:MAPT) causesNoChange a(HBP:"Tau aggregates")
pmid:25374103 tloc(p(HGNC:MAPT), fromLoc(GO:axon), toLoc(GO:"somatodendritic compartment")) increases a(HBP:"Tau aggregates")
pmid:28420982 sec(p(HGNC:MAPT)) association a(HBP:"Tau aggregates")
pmid:27373205 p(HGNC:MAPT) increases a(HBP:"Tau aggregates")
pmid:21882945 p(HGNC:MAPT) increases complex(a(GO:microtubule), p(HGNC:MAPT))
pmid:29191965 p(HGNC:MAPT) increases complex(a(GO:microtubule), p(HGNC:MAPT))
pmid:26631930 p(HGNC:MAPT) directlyIncreases complex(a(GO:microtubule), p(HGNC:MAPT))
pmid:21882945 deg(p(HGNC:MAPT)) negativeCorrelation bp(GO:aging)
pmid:21882945 p(HGNC:MAPT) increases path(HBP:neurotoxicity)
pmid:21882945 deg(p(HGNC:MAPT)) negativeCorrelation p(HGNC:AKT1)
pmid:30126037 p(HGNC:MAPT) association path(MESH:"Brain Injuries, Traumatic")
pmid:22419736 p(HGNC:MAPT) increases path(MESH:"Retinal Degeneration")
pmid:29191965 p(HGNC:MAPT) increases complex(p(HGNC:MAPT), p(HGNC:TUBA1A))
pmid:29191965 p(HGNC:MAPT) increases complex(p(HGNC:MAPT), p(HGNC:TUBB))
pmid:29191965 p(HGNC:MAPT) association a(GO:"cell body")
pmid:25374103 p(HGNC:MAPT) decreases bp(GO:"anterograde axonal transport")
pmid:26631930 p(HGNC:MAPT) decreases bp(GO:"anterograde axonal transport")
pmid:28420982 p(HGNC:MAPT) regulates bp(GO:"generation of neurons")
pmid:28420982 p(HGNC:MAPT) increases bp(HP:Neurodegeneration)
pmid:28420982 p(HGNC:MAPT) increases bp(GO:"cell death")
pmid:28420982 p(HGNC:MAPT) association bp(GO:behavior)
pmid:28420982 p(HGNC:MAPT) decreases bp(GO:"synaptic signaling")
pmid:28420982 p(HGNC:MAPT) association bp(GO:"intracellular signal transduction")
pmid:28420982 tloc(p(HGNC:MAPT), fromLoc(GO:axon), toLoc(GO:"cell body")) association bp(MESH:Aging)
pmid:28420982 tloc(p(HGNC:MAPT), fromLoc(GO:axon), toLoc(GO:dendrite)) association bp(MESH:Aging)
pmid:28420982 sec(p(HGNC:MAPT)) association a(MESH:Exosomes)
pmid:29238289 p(HGNC:MAPT) association act(a(MESH:Exosomes))
pmid:28420982 sec(p(HGNC:MAPT)) association a(GO:microvesicle)
pmid:28420982 p(HGNC:MAPT) increases a(CHEBI:"calcium(2+)")
pmid:28420982 p(HGNC:MAPT) increases bp(GO:"neuron death")
pmid:29238289 p(HGNC:MAPT) causesNoChange bp(GO:"neuron death")
pmid:16566606 act(p(HGNC:MAPT)) negativeCorrelation p(HGNC:MAPT, pmod(Ph, Tyr, 394))
pmid:26751493 p(HGNC:MAPT) decreases act(p(HGNC:HDAC6))
pmid:26751493 p(HGNC:MAPT) regulates bp(MESH:"Transcription, Genetic")
pmid:26751493 p(HGNC:MAPT) decreases bp(GO:autophagy)
pmid:26751493 p(HGNC:MAPT) positiveCorrelation bp(GO:"clathrin-dependent endocytosis")
pmid:27373205 p(HGNC:MAPT) increases a(HBP:"Tau oligomers")
pmid:26631930 p(HGNC:MAPT) directlyIncreases complex(p(HGNC:FYN), p(HGNC:MAPT))
pmid:18680553 p(HGNC:MAPT) increases complex(p(HGNC:FYN), p(HGNC:MAPT))
pmid:26631930 p(HGNC:MAPT) directlyIncreases p(HGNC:MAPT, pmod(Ac, Lys, 280))
pmid:16566606 act(p(HGNC:MAPT)) negativeCorrelation p(HGNC:MAPT, pmod(HBP:nitration, Tyr, 18))
pmid:16566606 act(p(HGNC:MAPT)) negativeCorrelation p(HGNC:MAPT, pmod(HBP:nitration, Tyr, 29))
pmid:26631930 tloc(p(HGNC:MAPT), fromLoc(GO:axon), toLoc(MESH:"Dendritic Spines")) association path(HBP:Neurodegeneration)
pmid:26631930 act(p(HGNC:MAPT)) decreases path(HBP:Neurodegeneration)
pmid:26631930 p(HGNC:MAPT) association act(a(MESH:Dyneins))
pmid:26631930 p(HGNC:MAPT) association act(a(MESH:Kinesin))
pmid:26631930 p(HGNC:MAPT) decreases complex(a(GO:microtubule), a(MESH:Dyneins))
pmid:22817713 p(HGNC:MAPT) decreases complex(a(GO:microtubule), a(MESH:Dyneins))
pmid:26631930 p(HGNC:MAPT) decreases complex(a(GO:microtubule), a(MESH:Kinesin))
pmid:22817713 p(HGNC:MAPT) decreases complex(a(GO:microtubule), a(MESH:Kinesin))
pmid:26631930 p(HGNC:MAPT) decreases bp(GO:"retrograde axonal transport")
pmid:26631930 p(HGNC:MAPT) increases act(p(HGNC:GSK3B))
pmid:26631930 p(HGNC:MAPT) increases act(p(HGNC:PPP1R8))
pmid:26631930 p(HGNC:MAPT) directlyIncreases complex(p(HGNC:DCTN1), p(HGNC:MAPT))
pmid:8391280 p(HGNC:MAPT) isA complex(p(HGNC:DCTN1), p(HGNC:MAPT))
pmid:26631930 p(HGNC:MAPT) increases a(MESH:Neurites)
pmid:26631930 p(HGNC:MAPT) association bp(GO:"regulation of synaptic plasticity")
pmid:26631930 p(HGNC:MAPT) increases path(HBP:Excitotoxicity)
pmid:26631930 p(HGNC:MAPT) association bp(GO:neurogenesis)
pmid:26631930 p(HGNC:MAPT) increases bp(GO:neurogenesis)
pmid:26631930 p(HGNC:MAPT) decreases a(CHEBI:"iron(0)")
pmid:26631930 p(HGNC:MAPT) decreases a(CHEBI:"iron(0)")
pmid:26631930 p(HGNC:MAPT) increases bp(GO:locomotion)
pmid:26631930 p(HGNC:MAPT) increases tloc(p(HGNC:APP), fromLoc(GO:cytoplasm), toLoc(GO:"cell surface"))
pmid:26631930 p(HGNC:MAPT) increases bp(GO:"long-term synaptic depression")
pmid:26631930 p(HGNC:MAPT) increases bp(GO:"long-term synaptic depression")
pmid:26631930 p(HGNC:MAPT) directlyIncreases complex(a(MESH:Actins), p(HGNC:MAPT))
pmid:26631930 p(HGNC:MAPT) increases act(a(MESH:Brain))
pmid:26631930 p(HGNC:MAPT) negativeCorrelation path(MESH:Dementia)
pmid:26631930 p(HGNC:MAPT) increases bp(GO:"iron ion transport")
pmid:26631930 p(HGNC:MAPT) increases bp(GO:"DNA protection")
pmid:26631930 tloc(p(HGNC:MAPT), fromLoc(GO:axon), toLoc(MESH:"Dendritic Spines")) regulates act(a(CHEBI:"amyloid-beta"))
pmid:26631930 p(HGNC:MAPT) increases act(a(CHEBI:"amyloid-beta"))
pmid:26631930 tloc(p(HGNC:MAPT), fromLoc(GO:axon), toLoc(MESH:"Dendritic Spines")) increases tloc(p(HGNC:TTLL6), fromLoc(GO:axon), toLoc(MESH:"Dendritic Spines"))
pmid:26631930 p(HGNC:MAPT) increases complex(p(HGNC:DLG4), p(HGNC:FYN))
pmid:22817713 p(HGNC:MAPT) association bp(GO:"regulation of microtubule cytoskeleton organization")
pmid:29626319 p(HGNC:MAPT) decreases p(HGNC:PSMD7)
pmid:29238289 p(HGNC:MAPT) association bp(GO:"microtubule polymerization")
pmid:2123288 act(p(HGNC:MAPT)) increases bp(GO:"microtubule polymerization")
pmid:16566606 p(HGNC:MAPT) increases bp(GO:"microtubule polymerization")
pmid:29238289 p(HGNC:MAPT) association a(MESH:Microtubules)
pmid:29238289 p(HGNC:MAPT, loc(GO:"extracellular region")) increases path(MESH:"Cytotoxicity, Immunologic")
pmid:29238289 sec(p(HGNC:MAPT)) association p(HGNC:RAB7A)
pmid:29238289 sec(p(HGNC:MAPT)) association p(HGNC:RAB1A)
pmid:29238289 sec(p(HGNC:MAPT)) association a(MESH:"Transport Vesicles")
pmid:29238289 p(HGNC:MAPT) decreases tloc(p(HBP:"Tau aggregates"), fromLoc(MESH:"Extracellular Space"), toLoc(MESH:"Intracellular Space"))
pmid:1918161 p(HGNC:MAPT) directlyIncreases complex(GO:microtubule)
pmid:6543144 p(HGNC:MAPT) association complex(GO:microtubule)
pmid:10464280 p(HGNC:MAPT) association complex(GO:microtubule)
pmid:1918161 p(HGNC:MAPT) positiveCorrelation complex(GO:axon)
pmid:1918161 p(HGNC:MAPT) positiveCorrelation complex(GO:"neuron projection")
pmid:6543144 p(HGNC:MAPT) association complex(GO:neurofilament)
pmid:2446784 p(HGNC:MAPT) association complex(GO:"polysomal ribosome")
pmid:11812770 p(HGNC:MAPT) positiveCorrelation complex(p(HGNC:GSK3B), p(HGNC:MAPT))
pmid:18680553 p(HGNC:MAPT) association p(HGNC:FYN)
pmid:18680553 p(HGNC:MAPT) association bp(GO:myelination)
pmid:18467332 p(HGNC:MAPT) association p(HGNC:SRC, frag("84_145"))
pmid:18467332 p(HGNC:MAPT) isA complex(p(HGNC:MAPT), p(HGNC:SRC))
pmid:18467332 p(HGNC:MAPT) association p(HGNC:PLCG1, frag("790_851"))
pmid:18467332 p(HGNC:MAPT) isA complex(p(HGNC:MAPT), p(HGNC:PLCG1))
pmid:18467332 p(HGNC:MAPT) association p(HGNC:GRB2, frag("1_57"))
pmid:18467332 p(HGNC:MAPT) association complex(p(HGNC:GRB2), p(HGNC:MAPT))
pmid:18467332 p(HGNC:MAPT) association p(HGNC:PIK3R1, frag("3_79"))
pmid:18467332 p(HGNC:MAPT) isA complex(p(HGNC:MAPT), p(HGNC:PIK3R1))
pmid:10464280 p(HGNC:MAPT) increases complex(complex(GO:microtubule), p(HGNC:MAPT))
pmid:17954934 p(HGNC:MAPT) isA complex(p(HGNC:BAG1), p(HGNC:MAPT), p(HGNC:STUB1))
pmid:17954934 p(HGNC:MAPT) positiveCorrelation p(HGNC:BAG1)
pmid:8391280 p(HGNC:MAPT) increases act(p(INTERPRO:"Dynein associated protein"))
pmid:20071522 p(HGNC:MAPT) isA complex(p(HGNC:FKBP5), p(HGNC:MAPT))
pmid:21367866 deg(p(HGNC:MAPT)) negativeCorrelation act(p(FPLX:HSP90))
pmid:2123288 p(HGNC:MAPT) isA complex(p(FPLX:CALM), p(HGNC:MAPT))
pmid:2123288 act(p(HGNC:MAPT)) negativeCorrelation complex(a(CHEBI:"calcium(2+)"), p(FPLX:CALM), p(HGNC:MAPT))
pmid:2833519 p(HGNC:MAPT) association p(HGNC:S100B)
pmid:2833519 p(HGNC:MAPT) isA complex(p(HGNC:MAPT), p(HGNC:S100B))
pmid:12551948 p(HGNC:MAPT) association p(HGNC:YWHAZ)
pmid:12551948 p(HGNC:MAPT) isA complex(p(HGNC:GSK3B), p(HGNC:MAPT), p(HGNC:YWHAZ))
pmid:21339331 p(HGNC:MAPT) association p(HGNC:ANXA2)
pmid:21339331 p(HGNC:MAPT) isA complex(a(MESH:"Cell Membrane"), p(HGNC:ANXA2), p(HGNC:MAPT))
pmid:21131359 p(HGNC:MAPT) association a(CHEBI:"double-stranded DNA")
pmid:21131359 p(HGNC:MAPT) isA complex(a(CHEBI:"double-stranded DNA"), p(HGNC:MAPT))
pmid:21131359 p(HGNC:MAPT) negativeCorrelation bp(MESH:"Hot Temperature")
pmid:16566606 act(p(HGNC:MAPT)) negativeCorrelation p(HGNC:MAPT, pmod(HBP:nitration, Tyr, 197))
pmid:16566606 p(HGNC:MAPT) increases bp(GO:"tubulin complex assembly")
pmid:24869773 p(HGNC:MAPT) association p(HGNC:MAPT, pmod(Me, Lys, 24))
pmid:24869773 p(HGNC:MAPT) association p(HGNC:MAPT, pmod(Me, Lys, 44))
pmid:24869773 p(HGNC:MAPT) association p(HGNC:MAPT, pmod(Me, Lys, 67))
pmid:24869773 p(HGNC:MAPT) association p(HGNC:MAPT, pmod(Me, Lys, 190))
pmid:19251756 p(HGNC:MAPT) association p(INTERPRO:"Triosephosphate isomerase", pmod(NO))
pmid:19251756 p(HGNC:MAPT) partOf complex(p(HGNC:MAPT), p(INTERPRO:"Triosephosphate isomerase", pmod(NO)))
pmid:10537045 p(HGNC:MAPT) positiveCorrelation p(HGNC:TGM2)
pmid:10537045 p(HGNC:MAPT) partOf complex(p(HGNC:MAPT), p(HGNC:TGM2))
pmid:24853415 p(HGNC:MAPT) positiveCorrelation p(HGNC:DAPK1)
pmid:24853415 p(HGNC:MAPT) positiveCorrelation p(HGNC:PIN1, pmod(Ph, Ser, 71))
pmid:25652642 a(GO:"neurofibrillary tangle") positiveCorrelation act(complex(GO:"NF-kappaB complex"))
pmid:29196815 a(GO:"neurofibrillary tangle") positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:28420982 a(GO:"neurofibrillary tangle") positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:22817713 a(GO:"neurofibrillary tangle") association path(MESH:"Alzheimer Disease")
pmid:11089576 a(GO:"neurofibrillary tangle") positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:24653673 a(GO:"neurofibrillary tangle") association p(FPLX:PPP2, pmod(Me, Tyr, 307))
pmid:29758300 a(GO:"neurofibrillary tangle") association p(HGNC:BECN1, frag("?"))
pmid:22908190 a(GO:"neurofibrillary tangle") association a(HBP:"paired helical filaments")
pmid:22908190 a(GO:"neurofibrillary tangle") association a(MESH:Ubiquitin)
pmid:22908190 a(GO:"neurofibrillary tangle") negativeCorrelation act(complex(GO:"proteasome complex"))
pmid:22908190 a(GO:"neurofibrillary tangle") negativeCorrelation p(HGNC:UCHL1, pmod(GO:"protein oxidation"))
pmid:22908190 a(GO:"neurofibrillary tangle") association bp(GO:"protein K63-linked ubiquitination")
pmid:22908190 a(GO:"neurofibrillary tangle") association p(HGNC:MAPT, pmod(HBP:hyperphosphorylation))
pmid:18930136 a(GO:"neurofibrillary tangle") association p(HGNC:SQSTM1)
pmid:27671637 a(GO:"neurofibrillary tangle") positiveCorrelation p(HBP:"Tau isoform F (441 aa)", var("p.Lys280del"))
pmid:30126037 a(GO:"neurofibrillary tangle") decreases bp(GO:cognition)
pmid:30126037 a(GO:"neurofibrillary tangle") increases bp(GO:"cell death")
pmid:30126037 a(GO:"neurofibrillary tangle") decreases bp(GO:"cell death")
pmid:30126037 a(GO:"neurofibrillary tangle") positiveCorrelation p(MGI:Cdkn2a)
pmid:30126037 a(GO:"neurofibrillary tangle") increases act(p(MGI:Cdkn2a))
pmid:30126037 a(GO:"neurofibrillary tangle") increases p(MGI:Cdkn2a)
pmid:30126037 a(GO:"neurofibrillary tangle") increases p(MGI:Cdkn2a)
pmid:30126037 a(GO:"neurofibrillary tangle") association bp(GO:"cellular senescence")
pmid:30126037 a(GO:"neurofibrillary tangle") increases bp(MESH:"Cell Survival")
pmid:30126037 a(GO:"neurofibrillary tangle") increases bp(GO:"inflammatory response")
pmid:30126037 a(GO:"neurofibrillary tangle") increases bp(GO:"cell cycle")
pmid:30126037 a(GO:"neurofibrillary tangle") decreases bp(GO:"apoptotic process")
pmid:30126037 a(GO:"neurofibrillary tangle") decreases path(MESH:Necrosis)
pmid:30126037 a(GO:"neurofibrillary tangle") increases p(HGNC:NFKB1)
pmid:30126037 a(GO:"neurofibrillary tangle") increases p(HGNC:IFNG)
pmid:30126037 a(GO:"neurofibrillary tangle") increases p(HGNC:TNF)
pmid:30126037 a(GO:"neurofibrillary tangle") increases p(HGNC:TLR4)
pmid:30126037 a(GO:"neurofibrillary tangle") increases p(HGNC:IL1B)
pmid:30126037 a(GO:"neurofibrillary tangle") increases p(HGNC:CXCL1)
pmid:30126037 a(GO:"neurofibrillary tangle") increases act(p(MGI:Ifng))
pmid:30126037 a(GO:"neurofibrillary tangle") increases act(p(MGI:Tnf))
pmid:30126037 a(GO:"neurofibrillary tangle") increases act(p(MGI:Il1b))
pmid:30126037 a(GO:"neurofibrillary tangle") increases act(p(MGI:Jak1))
pmid:30126037 a(GO:"neurofibrillary tangle") increases act(p(MGI:Stat1))
pmid:30126037 a(GO:"neurofibrillary tangle") increases act(p(MGI:Bcl2))
pmid:30126037 a(GO:"neurofibrillary tangle") association p(HGNC:CDKN2A)
pmid:30126037 a(GO:"neurofibrillary tangle") positiveCorrelation p(HGNC:CDKN2A)
pmid:30126037 a(GO:"neurofibrillary tangle") increases p(HGNC:CDKN2A)
pmid:30126037 a(GO:"neurofibrillary tangle") decreases bp(GO:"oxygen transport")
pmid:30126037 a(GO:"neurofibrillary tangle") association path(MESH:"Hypertrophy, Right Ventricular")
pmid:30126037 a(GO:"neurofibrillary tangle") association path(MESH:"Hypertrophy, Left Ventricular")
pmid:30126037 a(GO:"neurofibrillary tangle") association path(HP:"Brain atrophy")
pmid:30985105 deg(a(GO:"neurofibrillary tangle")) negativeCorrelation p(MESH:Proteins, pmod(HBP:"O-GlcNAcylation"))
pmid:26751493 a(GO:"neurofibrillary tangle") negativeCorrelation r(HGNC:SYP)
pmid:26751493 a(GO:"neurofibrillary tangle") negativeCorrelation p(HGNC:SNAP25)
pmid:26751493 a(GO:"neurofibrillary tangle") negativeCorrelation p(PFAM:Syntaxin)
pmid:23531502 a(GO:"neurofibrillary tangle") association act(a(CHEBI:acrolein))
pmid:12578227 a(GO:"neurofibrillary tangle") positiveCorrelation p(HGNC:TGM1)
pmid:12578227 a(GO:"neurofibrillary tangle") positiveCorrelation p(HGNC:TGM2)
pmid:11089576 a(GO:"neurofibrillary tangle") positiveCorrelation act(p(ECCODE:"2.3.2.13"))
pmid:11738469 a(GO:"neurofibrillary tangle") positiveCorrelation act(p(ECCODE:"2.3.2.13"))
pmid:8985134 a(GO:"neurofibrillary tangle") positiveCorrelation act(p(ECCODE:"2.3.2.13"))
pmid:11089576 a(GO:"neurofibrillary tangle") positiveCorrelation path(MESH:"Supranuclear Palsy, Progressive")
pmid:9099822 a(GO:"neurofibrillary tangle") positiveCorrelation act(p(HGNCGENEFAMILY:Transglutaminases))
pmid:23088643 a(GO:"neurofibrillary tangle") association p(HBP:"Tau epitope, AT8")
pmid:23088643 a(GO:"neurofibrillary tangle") association p(HGNC:MAPT, pmod(Ph, Ser, 422))
pmid:26751493 a(GO:"neurofibrillary tangle") negativeCorrelation p(INTERPRO:"Syntaxin, N-terminal domain")
pmid:26118667 a(GO:"neurofibrillary tangle") positiveCorrelation p(HBP:"CDK5R1 p25")
pmid:29844403 a(GO:"neurofibrillary tangle") positiveCorrelation a(HBP:"Tau aggregates")
pmid:21734277 a(GO:"neurofibrillary tangle") decreases bp(GO:"axonal transport")
pmid:21734277 a(GO:"neurofibrillary tangle") increases act(p(FPLX:PPP1))
pmid:21734277 a(GO:"neurofibrillary tangle") increases act(p(HGNC:GSK3B))
pmid:23832849 a(GO:"neurofibrillary tangle") association p(HGNC:FKBP1A)
pmid:30663117 g(HGNC:"MIR9-1") decreases a(GO:"neurofibrillary tangle")
pmid:30663117 g(HGNC:"MIR9-1") decreases act(p(HGNC:MAP2K2))
pmid:30663117 g(HGNC:"MIR9-1") association path(MESH:"Alzheimer Disease")
pmid:30663117 act(p(HGNC:MAP2K2)) increases a(GO:"neurofibrillary tangle")
pmid:30663117 a(MESH:"RNA, Long Noncoding") increases bp(GO:"apoptotic process")
pmid:28745240 bp(GO:"apoptotic process") negativeCorrelation p(HGNC:RELA)
pmid:27288790 bp(GO:"apoptotic process") association p(FPLX:NFkappaB)
pmid:19293145 bp(GO:"apoptotic process") association p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits")
pmid:24653673 bp(GO:"apoptotic process") positiveCorrelation act(p(HGNC:GSK3B))
pmid:24653673 bp(GO:"apoptotic process") positiveCorrelation act(p(HGNC:CDK5))
pmid:24653673 bp(GO:"apoptotic process") positiveCorrelation act(p(FPLX:ERK))
pmid:30012004 bp(GO:"apoptotic process") positiveCorrelation path(MESH:"Huntington Disease")
pmid:24027553 bp(GO:"apoptotic process") increases act(p(HGNCGENEFAMILY:Calpains))
pmid:24027553 bp(GO:"apoptotic process") increases p(HGNC:MAPT, frag("?", "17kD"))
pmid:24027553 bp(GO:"apoptotic process") increases act(p(HGNC:CASP6))
pmid:26304819 bp(GO:"apoptotic process") association r(HGNC:GAPDH)
pmid:23948915 bp(GO:"apoptotic process") negativeCorrelation p(HGNC:MAPT, pmod(Ph, Ser, 262))
pmid:23948915 bp(GO:"apoptotic process") negativeCorrelation p(HGNC:MAPT, pmod(Ph, Ser, 396))
pmid:23948915 bp(GO:"apoptotic process") negativeCorrelation p(HGNC:MAPT, pmod(Ph, Thr, 231))
pmid:30663117 g(HGNC:EBF3) isA a(MESH:"RNA, Long Noncoding")
pmid:30663117 bp(GO:"neuron death") increases g(MGI:Ebf3)
pmid:30444369 bp(GO:"neuron death") association p(HGNC:SH3GL2)
pmid:29196815 bp(GO:"neuron death") positiveCorrelation a(HBP:HBP00074)
pmid:21214928 bp(GO:"neuron death") association complex(a(HBP:HBP00042), p(HGNC:TNFRSF21))
pmid:22122372 bp(GO:"neuron death") association path(MESH:"Alzheimer Disease")
pmid:17009926 bp(GO:"neuron death") positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:17009926 bp(GO:"neuron death") positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:25514383 bp(GO:"neuron death") positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:21722302 bp(GO:"neuron death") prognosticBiomarkerFor path(MESH:"Alzheimer Disease")
pmid:28420982 bp(GO:"neuron death") positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:26631930 bp(GO:"neuron death") positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:21787755 bp(GO:"neuron death") association a(HBP:"alpha-7-containing nAChR")
pmid:30012004 bp(GO:"neuron death") increases path(MESH:Atrophy)
pmid:30012004 bp(GO:"neuron death") positiveCorrelation path(MESH:"Huntington Disease")
pmid:30012004 bp(GO:"neuron death") positiveCorrelation path(MESH:"Huntington Disease")
pmid:21722302 bp(GO:"neuron death") association p(HGNC:PRNP)
pmid:29758300 bp(GO:"neuron death") association path(MESH:"Neurodegenerative Diseases")
pmid:14556719 bp(GO:"neuron death") positiveCorrelation path(MESH:"Parkinson Disease")
pmid:22908190 bp(GO:"neuron death") positiveCorrelation act(p(HGNC:RAB5A))
pmid:24027553 bp(GO:"neuron death") negativeCorrelation bp(MESH:Autophagy)
pmid:21882945 bp(GO:"neuron death") positiveCorrelation path(MESH:Tauopathies)
pmid:28420982 bp(GO:"neuron death") association path(MESH:Tauopathies)
pmid:30663117 a(HBP:"alpha-synuclein aggregates") association path(MESH:"Parkinson Disease")
pmid:30663117 a(HBP:"alpha-synuclein aggregates") increases path(MESH:"Parkinson Disease")
pmid:30663117 a(HBP:"alpha-synuclein aggregates") decreases a(MESH:"Dopaminergic Neurons")
pmid:30663117 a(HBP:"alpha-synuclein aggregates") negativeCorrelation a(MESH:"HSP70 Heat-Shock Proteins")
pmid:29758300 a(HBP:"alpha-synuclein aggregates") association path(MESH:"Alzheimer Disease")
pmid:29758300 a(HBP:"alpha-synuclein aggregates") positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:14556719 a(HBP:"alpha-synuclein aggregates") association a(MESH:"Lewy Bodies")
pmid:14556719 a(HBP:"alpha-synuclein aggregates") positiveCorrelation path(MESH:"Parkinsonian Disorders")
pmid:14556719 a(HBP:"alpha-synuclein aggregates") decreases bp(GO:"proteasome-mediated ubiquitin-dependent protein catabolic process")
pmid:30116051 a(HBP:"alpha-synuclein aggregates") decreases complex(GO:"proteasome complex")
pmid:30985105 a(HBP:"alpha-synuclein aggregates") decreases bp(GO:"neuron death")
pmid:30985105 a(HBP:"alpha-synuclein aggregates") negativeCorrelation a(HBP:"alpha-synuclein oligomers")
pmid:21482353 a(MESH:"Dopaminergic Neurons") positiveCorrelation a(HBP:"alpha-4 beta-2 nAChR")
pmid:19721446 a(MESH:"Dopaminergic Neurons") association complex(p(HGNC:CHRNA4), p(HGNC:CHRNA6), p(HGNC:CHRNB2), p(HGNC:CHRNB3))
pmid:19721446 a(MESH:"Dopaminergic Neurons") association complex(p(HGNC:CHRNA6), p(HGNC:CHRNB2), p(HGNC:CHRNB3))
pmid:19721446 a(MESH:"Dopaminergic Neurons") association complex(p(HGNC:CHRNA6), p(HGNC:CHRNB2))
pmid:19721446 a(MESH:"Dopaminergic Neurons") association complex(p(HGNC:CHRNA4), p(HGNC:CHRNB2))
pmid:19721446 a(MESH:"Dopaminergic Neurons") association complex(p(HGNC:CHRNA4), p(HGNC:CHRNA5), p(HGNC:CHRNB2))
pmid:28901280 a(MESH:"Dopaminergic Neurons") regulates a(MESH:Nicotine)
pmid:14556719 a(MESH:"Dopaminergic Neurons") negativeCorrelation p(HGNC:PRKN)
pmid:30663117 p(HGNC:SNCA) association bp(GO:"synaptic transmission, dopaminergic")
pmid:30663117 p(HGNC:SNCA) positiveCorrelation a(GO:"Lewy body", loc(MESH:"Dopaminergic Neurons"))
pmid:29758300 p(HGNC:SNCA) positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:29758300 p(HGNC:SNCA) increases path(MESH:"Alzheimer Disease")
pmid:29758300 p(HGNC:SNCA) increases path(MESH:"Parkinson Disease")
pmid:28803412 p(HGNC:SNCA) association path(MESH:"Parkinson Disease")
pmid:29980653 p(HGNC:SNCA) positiveCorrelation path(MESH:"Parkinson Disease")
pmid:29758300 p(HGNC:SNCA) association bp(GO:"chaperone-mediated autophagy")
pmid:14556719 p(HGNC:SNCA) association p(HGNC:SNCAIP)
pmid:22908190 p(HGNC:SNCA) positiveCorrelation p(HGNC:SNCA, pmod(Ub))
pmid:14556719 p(HGNC:SNCA) regulates bp(GO:"dopamine secretion, neurotransmission")
pmid:14556719 p(HGNC:SNCA) regulates bp(GO:"dopamine secretion")
pmid:30985105 p(HGNC:SNCA) association bp(GO:"dopamine secretion")
pmid:14556719 p(HGNC:SNCA) positiveCorrelation bp(HBP:"Alpha-synuclein Oligomerization")
pmid:14556719 p(HGNC:SNCA) increases bp(GO:"apoptotic process")
pmid:14556719 act(p(HGNC:SNCA)) increases p(HGNC:SNCAIP, pmod(Ub))
pmid:14556719 act(p(HGNC:SNCA)) increases p(HGNC:TH, pmod(Ub))
pmid:14556719 act(p(HGNC:SNCA)) regulates bp(GO:"homeostatic process")
pmid:14556719 p(HGNC:SNCA) association a(MESH:"Inclusion Bodies")
pmid:22908190 p(HGNC:SNCA) increases complex(a(GO:"Lewy body"), p(HGNC:SNCA))
pmid:25784053 p(HGNC:SNCA) decreases bp(GO:autophagy)
pmid:25784053 p(HGNC:SNCA) decreases p(HGNC:RAB1A)
pmid:30985105 p(HGNC:SNCA) regulates a(GO:"synaptic vesicle")
pmid:30985105 p(HGNC:SNCA) increases a(HBP:"alpha-synuclein fibrils")
pmid:29980653 tloc(p(HGNC:SNCA), fromLoc(GO:"extracellular region"), toLoc(GO:intracellular)) increases a(HBP:"alpha-synuclein fibrils")
pmid:30663117 bp(GO:"synaptic transmission, dopaminergic") association p(HGNC:SNCA)
pmid:14556719 bp(GO:"synaptic transmission, dopaminergic") negativeCorrelation path(MESH:"Parkinson Disease")
pmid:30663117 p(HGNC:SNCA, var("?")) increases path(MESH:"Parkinson Disease")
pmid:18930136 p(HGNC:SNCA, var("?")) increases path(MESH:"Parkinson Disease")
pmid:30985105 p(HGNC:SNCA, var("?")) increases path(MESH:"Parkinson Disease")
pmid:30061532 p(HGNC:SNCA, var("?")) association path(MESH:"Psychotic Disorders")
pmid:27491084 p(HGNC:SNCA, var("?")) association path(HP:Neurodegeneration)
pmid:29758300 p(HGNC:SNCA, var("?")) association bp(GO:"chaperone-mediated autophagy")
pmid:14556719 p(HGNC:SNCA, var("?")) association path(MESH:"Parkinsonian Disorders")
pmid:14556719 p(HGNC:SNCA, var("?")) increases bp(GO:"apoptotic process")
pmid:18930136 p(HGNC:SNCA, var("?")) decreases tloc(p(HGNC:SNCA, var("?")), fromLoc(GO:cytoplasm), toLoc(GO:"lysosomal lumen"))
pmid:30116051 p(HGNC:SNCA, var("?")) decreases bp(GO:"autophagosome assembly")
pmid:30116051 p(HGNC:SNCA, var("?")) decreases a(GO:"lysosomal membrane")
pmid:30116051 p(HGNC:SNCA, var("?")) decreases complex(GO:"proteasome complex")
pmid:30663117 a(GO:"Lewy body", loc(MESH:"Dopaminergic Neurons")) positiveCorrelation p(HGNC:SNCA)
pmid:21722302 a(GO:"Lewy body") increases p(MESH:"alpha-Synuclein")
pmid:21722302 a(GO:"Lewy body") biomarkerFor path(MESH:"Parkinson Disease")
pmid:21722302 a(GO:"Lewy body") increases p(MESH:"alpha-Synuclein", pmod(HBP:misfolded))
pmid:22908190 a(GO:"Lewy body") association a(MESH:Ubiquitin)
pmid:22908190 a(GO:"Lewy body") association a(MESH:Ubiquitin)
pmid:22908190 a(GO:"Lewy body") positiveCorrelation path(MESH:Dementia)
pmid:22908190 a(GO:"Lewy body") positiveCorrelation path(MESH:Dementia)
pmid:22908190 a(GO:"Lewy body") association p(HGNC:MAPT)
pmid:18930136 a(GO:"Lewy body") association p(HGNC:SQSTM1)
pmid:30663117 g(HGNC:"MIR7-1") regulates p(HGNC:SNCA)
pmid:30663117 g(HGNC:"MIR7-1") decreases p(HGNC:SNCA)
pmid:30663117 g(HGNC:"MIR7-1") regulates p(HGNC:SNCA)
pmid:30663117 g(HGNC:"MIR7-1") decreases path(MESH:"Parkinson Disease")
pmid:30663117 complex(g(HGNC:"MIR153-1"), r(HGNC:SNCA)) decreases act(p(HGNC:SNCA))
pmid:30663117 complex(g(HGNC:"MIR153-1"), r(HGNC:SNCA)) decreases p(HGNC:SNCA)
pmid:30663117 complex(g(HGNC:"MIR7-1"), r(HGNC:SNCA)) decreases act(p(HGNC:SNCA))
pmid:30663117 complex(g(HGNC:"MIR7-1"), r(HGNC:SNCA)) decreases p(HGNC:SNCA)
pmid:30663117 g(HGNC:MIR34B) increases p(HGNC:PARK7)
pmid:30663117 g(HGNC:MIR34C) increases p(HGNC:PARK7)
pmid:30663117 g(HGNC:MIR132) regulates p(HGNC:SNCA)
pmid:30663117 g(HGNC:MIR132) decreases p(HGNC:SNCA)
pmid:30663117 g(HGNC:MIR132) regulates p(HGNC:SNCA)
pmid:30663117 g(HGNC:MIR132) association path(MESH:"Parkinson Disease")
pmid:30663117 g(HGNC:MIR132) decreases path(MESH:"Parkinson Disease")
pmid:30663117 g(HGNC:MIR132) association p(HGNC:NR4A2)
pmid:26631930 g(HGNC:MIR132) negativeCorrelation path(MESH:"Supranuclear Palsy, Progressive")
pmid:26631930 g(HGNC:MIR132) decreases p(HBP:"4R tau")
pmid:30663117 p(HGNC:NR4A2) association g(HGNC:MIR132)
pmid:30663117 g(NCBIGENE:406950) association path(MESH:"Parkinson Disease")
pmid:30663117 g(NCBIGENE:406950) decreases a(MESH:"HSP70 Heat-Shock Proteins")
pmid:30663117 g(NCBIGENE:406950) negativeCorrelation a(MESH:"HSP70 Heat-Shock Proteins")
pmid:30663117 g(NCBIGENE:406950) increases a(HBP:"alpha-synuclein aggregates")
pmid:30663117 a(MESH:"HSP70 Heat-Shock Proteins") negativeCorrelation a(HBP:"alpha-synuclein aggregates")
pmid:30663117 a(MESH:"HSP70 Heat-Shock Proteins") decreases a(HBP:"alpha-synuclein aggregates")
pmid:30663117 a(MESH:"HSP70 Heat-Shock Proteins") negativeCorrelation g(NCBIGENE:406950)
pmid:25374103 a(MESH:"HSP70 Heat-Shock Proteins") increases deg(p(HGNC:MAPT, pmod(HBP:misfolded)))
pmid:30663117 complex(a(MESH:"HSP70 Heat-Shock Proteins"), g(NCBIGENE:406950)) regulates act(a(MESH:"HSP70 Heat-Shock Proteins"))
pmid:30663117 g(HGNC:MIR133B) decreases path(MESH:"Parkinson Disease")
pmid:30663117 g(HGNC:MIR133B) regulates p(HGNC:SNCA)
pmid:30663117 p(HGNC:LRRK2) association path(MESH:"Parkinson Disease")
pmid:24113872 p(HGNC:LRRK2) positiveCorrelation path(MESH:"Parkinson Disease")
pmid:30663117 p(HGNC:LRRK2) decreases g(HGNC:MIRLET7A1)
pmid:30663117 p(HGNC:LRRK2) decreases act(g(HGNC:MIRLET7A1))
pmid:30663117 p(HGNC:LRRK2) decreases g(HGNC:MIR184)
pmid:30663117 p(HGNC:LRRK2) decreases act(g(HGNC:MIR184))
pmid:24113872 act(p(HGNC:LRRK2), ma(kin)) directlyIncreases p(MGI:Mapt, pmod(Ph, Thr, 149))
pmid:24113872 act(p(HGNC:LRRK2), ma(kin)) directlyIncreases p(MGI:Mapt, pmod(Ph, Thr, 153))
pmid:24113872 act(p(HGNC:LRRK2), ma(kin)) directlyIncreases p(MGI:Mapt, pmod(Ph, Thr, 205))
pmid:24113872 act(p(HGNC:LRRK2), ma(kin)) directlyIncreases p(HBP:"Tau aggregates")
pmid:24113872 act(p(HGNC:LRRK2), ma(kin)) directlyIncreases p(MGI:Mapt, pmod(Ph, Ser, 199))
pmid:24113872 act(p(HGNC:LRRK2), ma(kin)) directlyIncreases p(MGI:Mapt, pmod(Ph, Ser, 202))
pmid:30663117 p(HGNC:LRRK2, var("?")) increases bp(GO:"neuron death")
pmid:21722302 p(HGNC:LRRK2, var("?")) increases path(DOID:"autosomal dominant Parkinson's disease 1")
pmid:21722302 p(HGNC:LRRK2, var("?")) decreases bp(GO:"protein catabolic process")
pmid:21722302 p(HGNC:LRRK2, var("?")) increases a(HBP:"alpha-synuclein aggregates")
pmid:21722302 p(HGNC:LRRK2, var("?")) increases a(MESH:"Ubiquitinated Proteins")
pmid:21722302 p(HGNC:LRRK2, var("?")) decreases bp(GO:"lysosomal protein catabolic process")
pmid:21722302 p(HGNC:LRRK2, var("?")) decreases bp(GO:"regulation of protein oxidation")
pmid:21722302 p(HGNC:LRRK2, var("?")) increases bp(GO:"inflammatory response")
pmid:21722302 p(HGNC:LRRK2, var("?")) increases bp(MESH:Apoptosis)
pmid:30116051 p(HGNC:LRRK2, var("?")) association path(MESH:"Parkinson Disease")
pmid:30116051 p(HGNC:LRRK2, var("?")) decreases bp(GO:autophagy)
pmid:30116051 p(HGNC:LRRK2, var("?")) decreases act(p(HGNC:BECN1))
pmid:30116051 p(HGNC:LRRK2, var("?")) association bp(HBP:"APP processing")
pmid:30116051 p(HGNC:LRRK2, var("?")) decreases bp(GO:"proteasome-mediated ubiquitin-dependent protein catabolic process")
pmid:30663117 p(HGNC:LRRK2, var("p.Gly2019Ser")) increases path(MESH:"Parkinson Disease")
pmid:28803412 p(HGNC:LRRK2, var("p.Gly2019Ser")) increases path(MESH:"Neurodegenerative Diseases")
pmid:30663117 g(HGNC:MIR205) regulates p(HGNC:LRRK2)
pmid:30663117 g(HGNC:MIR205) regulates p(HGNC:LRRK2)
pmid:30663117 g(HGNC:MIRLET7A1) decreases p(HGNC:E2F1)
pmid:30663117 g(HGNC:MIRLET7A1) decreases act(p(HGNC:E2F1))
pmid:30663117 g(HGNC:MIRLET7A1) decreases p(HGNC:TFDP1)
pmid:30663117 g(HGNC:MIRLET7A1) decreases act(p(HGNC:TFDP1))
pmid:30663117 g(HGNC:MIR184) decreases p(HGNC:E2F1)
pmid:30663117 g(HGNC:MIR184) decreases act(p(HGNC:E2F1))
pmid:30663117 g(HGNC:MIR184) decreases p(HGNC:TFDP1)
pmid:30663117 g(HGNC:MIR184) decreases act(p(HGNC:TFDP1))
pmid:30663117 p(HGNC:PARK7) decreases a(HBP:"alpha-synuclein aggregates")
pmid:30663117 p(HGNC:PARK7) decreases bp(GO:"apoptotic process")
pmid:30663117 p(HGNC:PARK7) decreases bp(GO:"neuron death")
pmid:21722302 p(HGNC:PARK7) increases bp(GO:"detection of redox state")
pmid:21722302 p(HGNC:PARK7) regulates bp(MESH:"Protein Stability")
pmid:30663117 path(MESH:Chorea) association path(MESH:"Huntington Disease")
pmid:29687724 path(MESH:Chorea) association path(MESH:"Huntington Disease")
pmid:29687724 path(MESH:Chorea) association path(MESH:"Neural Pathways")
pmid:29687724 path(MESH:Chorea) association a(CHEBI:dopamine)
pmid:30663117 path(MESH:Dementia) association path(MESH:"Huntington Disease")
pmid:30012004 path(MESH:Dementia) positiveCorrelation path(MESH:"Huntington Disease")
pmid:19126755 path(MESH:Dementia) positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:19293145 path(MESH:Dementia) association path(MESH:"Alzheimer Disease")
pmid:24511233 path(MESH:Dementia) association path(MESH:"Alzheimer Disease")
pmid:25514383 path(MESH:Dementia) association path(MESH:"Alzheimer Disease")
pmid:26813123 path(MESH:Dementia) association bp(GO:"synaptic transmission, cholinergic")
pmid:25514383 path(MESH:Dementia) association bp(GO:aging)
pmid:29758300 path(MESH:Dementia) association path(MESH:Tauopathies)
pmid:22908190 path(MESH:Dementia) positiveCorrelation a(GO:"Lewy body")
pmid:22908190 path(MESH:Dementia) positiveCorrelation a(GO:"Lewy body")
pmid:22908190 path(MESH:Dementia) positiveCorrelation p(HGNC:SNCA, pmod(Ub))
pmid:26631930 path(MESH:Dementia) negativeCorrelation p(HGNC:MAPT)
pmid:27314526 path(MESH:Dementia) association sec(a(MESH:Interleukins))
pmid:27314526 path(MESH:Dementia) positiveCorrelation p(HGNC:IL1B)
pmid:27314526 path(MESH:Dementia) positiveCorrelation p(HGNC:IL18)
pmid:30663117 path(MESH:"Deglutition Disorders") association path(MESH:"Huntington Disease")
pmid:30663117 path(MESH:Aphasia) association path(MESH:"Huntington Disease")
pmid:30663117 path(MESH:Seizures) association path(MESH:"Huntington Disease")
pmid:21787755 path(MESH:Seizures) association a(HBP:"alpha-7-containing nAChR")
pmid:30663117 p(HGNC:HTT, var("?")) increases path(MESH:"Huntington Disease")
pmid:14556719 p(HGNC:HTT, var("?")) increases path(MESH:"Huntington Disease")
pmid:14556719 p(HGNC:HTT, var("?")) increases a(HBP:"huntingtin aggregates")
pmid:14556719 p(HGNC:HTT, var("?")) decreases act(complex(GO:"proteasome complex"))
pmid:14556719 p(HGNC:HTT, var("?")) increases bp(GO:"cell cycle arrest")
pmid:14556719 p(HGNC:HTT, var("?")) decreases bp(GO:"proteasome-mediated ubiquitin-dependent protein catabolic process")
pmid:14556719 p(HGNC:HTT, var("?")) decreases act(p(HBP:"20 S Proteasome"))
pmid:14556719 p(HGNC:HTT, var("?")) decreases deg(p(HGNC:TP53))
pmid:14556719 p(HGNC:HTT, var("?")) decreases bp(MESH:"Membrane Potential, Mitochondrial")
pmid:14556719 p(HGNC:HTT, var("?")) increases sec(a(CHEBI:"cytochrome c"))
pmid:14556719 p(HGNC:HTT, var("?")) increases act(p(FPLX:Caspase))
pmid:14556719 p(HGNC:HTT, var("?")) increases bp(GO:"apoptotic process")
pmid:25784053 p(HGNC:HTT, var("?")) increases p(FPLX:HSPA)
pmid:30116051 p(HGNC:HTT, var("?")) decreases bp(GO:autophagy)
pmid:30116051 p(HGNC:HTT, var("?")) decreases bp(GO:"cargo loading into vesicle")
pmid:30116051 p(HGNC:HTT, var("?")) decreases bp(GO:"autophagosome assembly")
pmid:14556719 p(HGNC:HTT) increases complex(p(HGNC:HTT), p(HGNC:UBA2))
pmid:30985105 p(HGNC:HTT) association bp(GO:"vesicle transport along microtubule")
pmid:30985105 p(HGNC:HTT) association p(HGNC:BDNF)
pmid:30985105 p(HGNC:HTT) decreases bp(GO:"apoptotic process")
pmid:30663117 g(HGNC:MIR196A1) association path(MESH:"Huntington Disease")
pmid:30663117 g(HGNC:MIR206) association path(MESH:"Huntington Disease")
pmid:30663117 g(HGNC:MIR301B) association path(MESH:"Huntington Disease")
pmid:30663117 g(HGNC:MIR92B) association path(MESH:"Huntington Disease")
pmid:30663117 g(HGNC:MIR378B) association path(MESH:"Huntington Disease")
pmid:30663117 g(HGNC:MIR208B) association path(MESH:"Huntington Disease")
pmid:30663117 g(HGNC:MIR449A) association path(MESH:"Huntington Disease")
pmid:30663117 g(HGNC:MIR22) decreases bp(GO:"neuron death")
pmid:25681350 a(PUBCHEM:14235) increases r(MGI:"chitinase-like 1")
pmid:25681350 a(PUBCHEM:14235) increases r(MGI:"avian reticuloendotheliosis viral (v-rel) oncogene related B")
pmid:25681350 r(MGI:"chitinase-like 1") positiveCorrelation r(MGI:"interleukin 1 alpha")
pmid:25681350 r(MGI:"chitinase-like 1") positiveCorrelation r(MGI:"interleukin 6")
pmid:25681350 r(MGI:"interleukin 1 alpha") positiveCorrelation r(MGI:"chitinase-like 1")
pmid:25681350 r(MGI:"interleukin 6") positiveCorrelation r(MGI:"chitinase-like 1")
pmid:25681350 p(MGI:"myelin oligodendrocyte glycoprotein", frag("35_50")) increases r(MGI:"chitinase-like 1")
pmid:25681350 p(MGI:"myelin oligodendrocyte glycoprotein", frag("35_50")) increases r(MGI:"interleukin 1 alpha")
pmid:25681350 p(MGI:"myelin oligodendrocyte glycoprotein", frag("35_50")) increases r(MGI:"interleukin 6")
pmid:25681350 p(MGI:"interleukin 1 alpha") increases complex(GO:"NF-kappaB complex")
pmid:25681350 p(MGI:"interleukin 1 alpha") increases p(MGI:"signal transducer and activator of transcription 3")
pmid:25681350 p(MGI:"interleukin 1 alpha") increases act(p(MGI:"signal transducer and activator of transcription 3"))
pmid:25681350 p(MGI:"interleukin 1 alpha") increases r(MGI:"chitinase-like 1")
pmid:25681350 p(MGI:"interleukin 1 alpha") increases r(MGI:"avian reticuloendotheliosis viral (v-rel) oncogene related B")
pmid:25681350 p(MGI:"interleukin 1 alpha") increases act(p(MGI:"avian reticuloendotheliosis viral (v-rel) oncogene related B"))
pmid:25681350 p(MGI:"interleukin 1 alpha") increases act(complex(p(MGI:"avian reticuloendotheliosis viral (v-rel) oncogene related B"), p(MGI:"nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105")))
pmid:25681350 p(MGI:"interleukin 1 alpha") increases complex(p(MGI:"avian reticuloendotheliosis viral (v-rel) oncogene related B"), p(MGI:"nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105"))
pmid:25681350 act(p(MGI:"interleukin 1 alpha")) increases complex(p(MGI:"avian reticuloendotheliosis viral (v-rel) oncogene related B"), p(MGI:"nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105"))
pmid:25681350 p(MGI:"interleukin 1 alpha") increases path(MESH:Glioblastoma)
pmid:25681350 p(MGI:"interleukin 1 alpha") increases complex(p(MGI:"avian reticuloendotheliosis viral (v-rel) oncogene related B"), p(MGI:"chitinase-like 1"), p(MGI:"nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105"))
pmid:25681350 p(MGI:"interleukin 1 alpha") regulates p(MGI:"chitinase-like 1")
pmid:25681350 p(MGI:"interleukin 1 alpha") increases p(MGI:"nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105")
pmid:28745240 complex(GO:"NF-kappaB complex") increases bp(MESH:"Synaptic Transmission")
pmid:28745240 complex(GO:"NF-kappaB complex") increases bp(MESH:"Synaptic Transmission")
pmid:25652642 act(complex(GO:"NF-kappaB complex")) increases bp(MESH:"Synaptic Transmission")
pmid:28745240 act(complex(GO:"NF-kappaB complex")) decreases bp(GO:"neuron death")
pmid:28745240 complex(GO:"NF-kappaB complex") decreases bp(GO:"neuron death")
pmid:28745240 complex(GO:"NF-kappaB complex") decreases bp(GO:"neuron death")
pmid:28745240 act(complex(GO:"NF-kappaB complex")) decreases bp(GO:"neuron death")
pmid:25652642 act(complex(GO:"NF-kappaB complex")) decreases bp(GO:"neuron death")
pmid:28745240 complex(GO:"NF-kappaB complex") increases bp(GO:"positive regulation of synaptic plasticity")
pmid:25652642 act(complex(GO:"NF-kappaB complex")) increases bp(GO:"positive regulation of synaptic plasticity")
pmid:28745240 complex(GO:"NF-kappaB complex") regulates bp(GO:cognition)
pmid:28745240 complex(GO:"NF-kappaB complex") regulates bp(GO:behavior)
pmid:28745240 complex(GO:"NF-kappaB complex") increases path(MESH:"Spatial Memory")
pmid:25652642 act(complex(GO:"NF-kappaB complex")) increases path(MESH:"Spatial Memory")
pmid:28745240 complex(GO:"NF-kappaB complex") increases bp(GO:memory)
pmid:28745240 complex(GO:"NF-kappaB complex") increases bp(GO:learning)
pmid:28745240 complex(GO:"NF-kappaB complex") increases act(p(HGNC:PRKACA))
pmid:28745240 complex(GO:"NF-kappaB complex") decreases p(HGNC:BCL2L1)
pmid:28745240 complex(GO:"NF-kappaB complex") increases p(HGNC:BCL2L1)
pmid:28745240 complex(GO:"NF-kappaB complex") increases p(HGNC:BCL2L1)
pmid:28745240 complex(GO:"NF-kappaB complex") decreases sec(a(PUBCHEM:16057918))
pmid:28745240 complex(GO:"NF-kappaB complex") decreases bp(GO:"apoptotic process")
pmid:28745240 complex(GO:"NF-kappaB complex") decreases bp(GO:"apoptotic process")
pmid:25652642 act(complex(GO:"NF-kappaB complex")) decreases bp(GO:"apoptotic process")
pmid:25652642 act(complex(GO:"NF-kappaB complex")) decreases bp(GO:"apoptotic process")
pmid:28745240 complex(GO:"NF-kappaB complex") increases p(HGNC:BCL2)
pmid:28745240 complex(GO:"NF-kappaB complex") increases p(HGNC:BCL2A1)
pmid:28745240 act(complex(GO:"NF-kappaB complex")) decreases act(a(MESH:"Amyloid beta-Peptides"))
pmid:28745240 act(complex(GO:"NF-kappaB complex")) increases p(HGNC:SOD2)
pmid:28745240 act(complex(GO:"NF-kappaB complex")) increases p(HGNC:SOD2)
pmid:25652642 act(complex(GO:"NF-kappaB complex")) increases act(p(HGNC:SOD2))
pmid:28745240 act(complex(GO:"NF-kappaB complex")) decreases p(MESH:Proteins, pmod(HBP:nitration))
pmid:28745240 act(complex(GO:"NF-kappaB complex")) increases bp(GO:neurogenesis)
pmid:28745240 act(complex(GO:"NF-kappaB complex")) increases bp(GO:neurogenesis)
pmid:28745240 act(complex(GO:"NF-kappaB complex")) increases bp(GO:neurogenesis)
pmid:28745240 complex(GO:"NF-kappaB complex") regulates a(MESH:"Neural Stem Cells")
pmid:28745240 act(complex(GO:"NF-kappaB complex")) negativeCorrelation a(MESH:"Cerebral Cortex")
pmid:28745240 act(complex(GO:"NF-kappaB complex")) increases bp(GO:"stem cell division")
pmid:28745240 complex(GO:"NF-kappaB complex") increases p(HGNC:IL6)
pmid:28745240 complex(GO:"NF-kappaB complex") increases p(HGNC:IL6)
pmid:28745240 complex(GO:"NF-kappaB complex") increases p(HGNC:IL6)
pmid:28745240 complex(GO:"NF-kappaB complex") increases p(HGNC:IL6)
pmid:25652642 complex(GO:"NF-kappaB complex") increases p(HGNC:IL6)
pmid:28745240 act(complex(GO:"NF-kappaB complex")) increases bp(GO:"astrocyte development")
pmid:28745240 complex(GO:"NF-kappaB complex") increases p(HGNC:LIF)
pmid:28745240 complex(GO:"NF-kappaB complex") increases p(HGNC:CNTF)
pmid:28745240 act(complex(GO:"NF-kappaB complex")) increases bp(GO:"dendritic spine organization")
pmid:28745240 act(complex(GO:"NF-kappaB complex")) increases bp(MESH:"Neuronal Outgrowth")
pmid:28745240 act(complex(GO:"NF-kappaB complex")) increases bp(MESH:"Neuronal Outgrowth")
pmid:28745240 act(complex(GO:"NF-kappaB complex")) increases bp(MESH:"Neuronal Outgrowth")
pmid:28745240 act(complex(GO:"NF-kappaB complex")) increases bp(MESH:"Neuronal Outgrowth")
pmid:28745240 act(complex(GO:"NF-kappaB complex")) increases a(GO:axon)
pmid:28745240 act(complex(GO:"NF-kappaB complex")) increases bp(GO:"axon guidance")
pmid:28745240 complex(GO:"NF-kappaB complex") increases p(HGNC:ITGB1)
pmid:28745240 complex(GO:"NF-kappaB complex") regulates p(HGNC:NCAM1)
pmid:28745240 complex(GO:"NF-kappaB complex") regulates p(HGNC:SLITRK1)
pmid:28745240 complex(GO:"NF-kappaB complex") regulates p(HGNC:GFRA1)
pmid:28745240 complex(GO:"NF-kappaB complex") regulates p(HGNC:TIAM1)
pmid:28745240 act(complex(GO:"NF-kappaB complex")) increases a(MESH:"Dendritic Cells")
pmid:28745240 act(complex(GO:"NF-kappaB complex")) increases a(GO:"dendritic branch")
pmid:28745240 act(complex(GO:"NF-kappaB complex")) increases p(HGNC:HES1)
pmid:28745240 act(complex(GO:"NF-kappaB complex")) increases p(HGNC:HES5)
pmid:28745240 complex(GO:"NF-kappaB complex") increases p(HGNC:MAP1B)
pmid:28745240 complex(GO:"NF-kappaB complex") increases p(HGNC:MAP2)
pmid:28745240 complex(GO:"NF-kappaB complex") regulates p(HGNC:C3)
pmid:28745240 complex(GO:"NF-kappaB complex") regulates p(HGNC:CFB)
pmid:28745240 complex(GO:"NF-kappaB complex") regulates p(HGNC:CR2)
pmid:28745240 complex(GO:"NF-kappaB complex") regulates p(HGNC:C4A)
pmid:28745240 complex(GO:"NF-kappaB complex") regulates p(HGNC:C4BPA)
pmid:28745240 complex(GO:"NF-kappaB complex") regulates p(HGNC:IL1B)
pmid:28745240 complex(GO:"NF-kappaB complex") increases p(HGNC:IL1B)
pmid:25652642 complex(GO:"NF-kappaB complex") increases p(HGNC:IL1B)
pmid:28745240 complex(GO:"NF-kappaB complex") increases act(p(HGNC:IL1A))
pmid:28745240 complex(GO:"NF-kappaB complex") increases p(HGNC:MAPT, pmod(Ph, Ser, 202), pmod(Ph, Thr, 205))
pmid:28745240 complex(GO:"NF-kappaB complex") increases p(HGNC:MAPT, pmod(Ph, Ser, 202), pmod(Ph, Thr, 205))
pmid:28745240 complex(GO:"NF-kappaB complex") increases act(complex(p(HGNC:CDK5), p(HGNC:CDK5R1)))
pmid:28745240 complex(GO:"NF-kappaB complex") regulates p(HGNC:TNF)
pmid:28745240 complex(GO:"NF-kappaB complex") increases p(HGNC:TNF)
pmid:28745240 complex(GO:"NF-kappaB complex") increases p(HGNC:TNF)
pmid:25652642 complex(GO:"NF-kappaB complex") increases p(HGNC:TNF)
pmid:28745240 act(complex(GO:"NF-kappaB complex")) increases sec(a(CHEBI:"amyloid-beta"))
pmid:28745240 act(complex(GO:"NF-kappaB complex")) increases a(CHEBI:"amyloid-beta")
pmid:28745240 complex(GO:"NF-kappaB complex") regulates a(CHEBI:"amyloid-beta")
pmid:28745240 complex(GO:"NF-kappaB complex") regulates a(CHEBI:"amyloid-beta")
pmid:25652642 act(complex(GO:"NF-kappaB complex")) regulates a(CHEBI:"amyloid-beta")
pmid:25652642 act(complex(GO:"NF-kappaB complex")) positiveCorrelation a(CHEBI:"amyloid-beta")
pmid:28745240 complex(GO:"NF-kappaB complex") increases p(HGNC:BACE1)
pmid:28745240 complex(GO:"NF-kappaB complex") increases p(HGNC:BACE1)
pmid:25652642 act(complex(GO:"NF-kappaB complex")) regulates p(HGNC:BACE1)
pmid:25652642 act(complex(GO:"NF-kappaB complex")) decreases p(HGNC:BACE1)
pmid:21958873 complex(GO:"NF-kappaB complex") regulates p(HGNC:BACE1)
pmid:25331948 complex(GO:"NF-kappaB complex") regulates p(HGNC:BACE1)
pmid:28745240 complex(GO:"NF-kappaB complex") regulates bp(HBP:"APP processing")
pmid:25652642 act(complex(GO:"NF-kappaB complex")) decreases bp(HBP:"APP processing")
pmid:25652642 act(complex(GO:"NF-kappaB complex")) positiveCorrelation bp(HBP:"APP processing")
pmid:28745240 complex(GO:"NF-kappaB complex") regulates p(HBP:C99)
pmid:28745240 complex(GO:"NF-kappaB complex") regulates act(complex(GO:"gamma-secretase complex"))
pmid:28745240 complex(GO:"NF-kappaB complex") increases act(complex(GO:"gamma-secretase complex"))
pmid:28745240 complex(GO:"NF-kappaB complex") regulates p(HGNC:PSEN1)
pmid:28745240 complex(GO:"NF-kappaB complex") regulates p(HGNC:APP)
pmid:28745240 complex(GO:"NF-kappaB complex") regulates p(HGNC:APP)
pmid:25652642 act(complex(GO:"NF-kappaB complex")) regulates p(HGNC:APP)
pmid:28745240 act(complex(GO:"NF-kappaB complex")) decreases bp(GO:"calcium ion homeostasis")
pmid:28745240 complex(GO:"NF-kappaB complex") increases p(HGNC:CXCL8)
pmid:25652642 act(complex(GO:"NF-kappaB complex")) increases bp(GO:"inflammatory response")
pmid:25652642 act(complex(GO:"NF-kappaB complex")) increases a(MESH:"Free Radicals")
pmid:25652642 act(complex(GO:"NF-kappaB complex")) positiveCorrelation a(GO:"neurofibrillary tangle")
pmid:25652642 act(complex(GO:"NF-kappaB complex")) positiveCorrelation path(MESH:"Plaque, Amyloid")
pmid:25652642 complex(GO:"NF-kappaB complex") association path(MESH:"Plaque, Amyloid")
pmid:25652642 act(complex(GO:"NF-kappaB complex")) decreases p(HBP:"sAPP-beta")
pmid:25652642 act(complex(GO:"NF-kappaB complex")) positiveCorrelation p(HBP:"sAPP-beta")
pmid:25652642 complex(GO:"NF-kappaB complex") association act(p(HGNC:APOE))
pmid:25652642 complex(GO:"NF-kappaB complex") increases bp(MESH:Neuroprotection)
pmid:25652642 complex(GO:"NF-kappaB complex") regulates bp(MESH:Neuroprotection)
pmid:25652642 act(complex(GO:"NF-kappaB complex")) decreases a(CHEBI:peroxynitrite)
pmid:25652642 act(complex(GO:"NF-kappaB complex")) decreases bp(GO:"membrane depolarization")
pmid:25652642 act(complex(GO:"NF-kappaB complex")) decreases a(MESH:"Cholinergic Neurons")
pmid:25652642 act(complex(GO:"NF-kappaB complex")) positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:25652642 complex(GO:"NF-kappaB complex") positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:25652642 complex(GO:"NF-kappaB complex") positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:25652642 act(complex(GO:"NF-kappaB complex")) increases act(a(MESH:Microglia))
pmid:25652642 act(complex(GO:"NF-kappaB complex")) increases act(a(MESH:Cytokines))
pmid:25652642 act(complex(GO:"NF-kappaB complex")) increases act(a(CHEBI:"glutamate(1-)"))
pmid:25652642 act(complex(GO:"NF-kappaB complex")) increases act(a(CHEBI:"reactive oxygen species"))
pmid:25652642 act(complex(GO:"NF-kappaB complex")) increases act(a(CHEBI:"reactive oxygen species"))
pmid:25652642 act(complex(GO:"NF-kappaB complex")) increases act(p(HGNC:NOS2))
pmid:25652642 act(complex(GO:"NF-kappaB complex")) increases act(p(HGNC:NOS2))
pmid:25652642 act(complex(GO:"NF-kappaB complex")) increases path(HBP:neurotoxicity)
pmid:25652642 complex(GO:"NF-kappaB complex") regulates m(HGNC:"MIR9-1")
pmid:25652642 complex(GO:"NF-kappaB complex") regulates m(HGNC:MIR34A)
pmid:25652642 complex(GO:"NF-kappaB complex") regulates m(HGNC:MIR125B1)
pmid:25652642 complex(GO:"NF-kappaB complex") regulates m(HGNC:MIR146A)
pmid:25652642 complex(GO:"NF-kappaB complex") regulates m(HGNC:MIR155)
pmid:25652642 complex(GO:"NF-kappaB complex") regulates m(HGNC:MIR339)
pmid:21958873 complex(GO:"NF-kappaB complex") regulates p(HGNC:CRP)
pmid:25331948 complex(GO:"NF-kappaB complex") regulates r(HGNC:BACE1)
pmid:25681350 p(MGI:"signal transducer and activator of transcription 3") association p(MGI:"chitinase-like 1")
pmid:25681350 p(MGI:"signal transducer and activator of transcription 3") increases p(MGI:"chitinase-like 1")
pmid:25681350 p(MGI:"signal transducer and activator of transcription 3") increases r(MGI:"chitinase-like 1")
pmid:25681350 act(p(MGI:"signal transducer and activator of transcription 3")) increases act(p(MGI:"interleukin 1 alpha"))
pmid:25681350 act(p(MGI:"signal transducer and activator of transcription 3")) increases act(p(MGI:"oncostatin M"))
pmid:25681350 p(MGI:"oncostatin M") increases complex(GO:"NF-kappaB complex")
pmid:25681350 p(MGI:"oncostatin M") increases p(MGI:"signal transducer and activator of transcription 3")
pmid:25681350 p(MGI:"oncostatin M") increases act(p(MGI:"signal transducer and activator of transcription 3"))
pmid:25681350 p(MGI:"oncostatin M") increases act(p(MGI:"signal transducer and activator of transcription 3"))
pmid:25681350 p(MGI:"oncostatin M") increases r(MGI:"chitinase-like 1")
pmid:25681350 p(MGI:"oncostatin M") increases path(MESH:Glioblastoma)
pmid:25681350 p(MGI:"oncostatin M") regulates p(MGI:"chitinase-like 1")
pmid:25681350 p(MGI:"oncostatin M") increases p(MGI:"chitinase-like 1")
pmid:25681350 p(MGI:"oncostatin M") increases complex(p(MGI:"chitinase-like 1"), p(MGI:"nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105"))
pmid:25681350 p(MGI:"oncostatin M") increases act(p(MGI:"interleukin 1 alpha"))
pmid:25681350 p(MGI:"oncostatin M") increases complex(p(MGI:"avian reticuloendotheliosis viral (v-rel) oncogene related B"), p(MGI:"nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105"))
pmid:25681350 p(MGI:"v-rel reticuloendotheliosis viral oncogene homolog A (avian)") association p(MGI:"chitinase-like 1")
pmid:25681350 p(MGI:"v-rel reticuloendotheliosis viral oncogene homolog A (avian)") association p(MGI:"chitinase-like 1")
pmid:25681350 p(MGI:"v-rel reticuloendotheliosis viral oncogene homolog A (avian)") association p(MGI:"chitinase-like 1")
pmid:25681350 p(MGI:"v-rel reticuloendotheliosis viral oncogene homolog A (avian)") decreases p(MGI:"chemokine (C-X-C motif) ligand 15")
pmid:25681350 p(MGI:"chitinase-like 1") association p(MGI:"v-rel reticuloendotheliosis viral oncogene homolog A (avian)")
pmid:25681350 p(MGI:"chitinase-like 1") association p(MGI:"v-rel reticuloendotheliosis viral oncogene homolog A (avian)")
pmid:25681350 p(MGI:"chitinase-like 1") association p(MGI:"v-rel reticuloendotheliosis viral oncogene homolog A (avian)")
pmid:25681350 p(MGI:"chitinase-like 1") association p(MGI:"signal transducer and activator of transcription 3")
pmid:25681350 p(MGI:"chitinase-like 1") association p(MGI:"reticuloendotheliosis oncogene")
pmid:25681350 p(MGI:"chitinase-like 1") association p(MGI:"nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100")
pmid:25681350 p(MGI:"chitinase-like 1") increases complex(p(MGI:"avian reticuloendotheliosis viral (v-rel) oncogene related B"), p(MGI:"chitinase-like 1"), p(MGI:"nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105"))
pmid:25681350 p(MGI:"chitinase-like 1") increases complex(a(GO:"NF-kappaB p50/p65 complex"), p(MGI:"chitinase-like 1"))
pmid:25681350 p(MGI:"nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha", var("?")) decreases act(p(MGI:"interleukin 1 alpha"))
pmid:25681350 p(MGI:"nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha", var("?")) decreases act(p(MGI:"oncostatin M"))
pmid:25681350 p(MGI:"avian reticuloendotheliosis viral (v-rel) oncogene related B") increases r(MGI:"chitinase-like 1")
pmid:25681350 p(MGI:"avian reticuloendotheliosis viral (v-rel) oncogene related B") regulates p(MGI:"chitinase-like 1")
pmid:25681350 p(MGI:"avian reticuloendotheliosis viral (v-rel) oncogene related B") regulates p(MGI:"chitinase-like 1")
pmid:25681350 p(MGI:"avian reticuloendotheliosis viral (v-rel) oncogene related B") increases p(MGI:"chitinase-like 1")
pmid:25681350 p(MGI:"avian reticuloendotheliosis viral (v-rel) oncogene related B") increases act(p(MGI:"interleukin 1 alpha"))
pmid:25681350 p(MGI:"avian reticuloendotheliosis viral (v-rel) oncogene related B") increases act(p(MGI:"oncostatin M"))
pmid:25681350 p(MGI:"nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105") increases r(MGI:"chitinase-like 1")
pmid:25681350 p(MGI:"nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105") regulates p(MGI:"chitinase-like 1")
pmid:25681350 p(MGI:"nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105") increases act(p(MGI:"interleukin 1 alpha"))
pmid:25681350 p(MGI:"nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105") increases act(p(MGI:"oncostatin M"))
pmid:25681350 p(MGI:"reticuloendotheliosis oncogene") association p(MGI:"chitinase-like 1")
pmid:25681350 p(MGI:"nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100") association p(MGI:"chitinase-like 1")
pmid:25681350 p(HGNC:IL1A) increases p(HGNC:RELB)
pmid:25681350 p(HGNC:IL1A) causesNoChange r(HGNC:CHI3L1)
pmid:25681350 p(HGNC:IL1A) causesNoChange r(HGNC:RELB)
pmid:28745240 act(p(HGNC:IL1A)) increases bp(GO:"p38MAPK cascade")
pmid:23702978 p(HGNC:IL1A) increases act(p(HGNC:IL1R1))
pmid:23702978 p(HGNC:IL1A) increases bp(GO:"inflammatory response")
pmid:25681350 p(HGNC:RELB) causesNoChange p(HGNC:CHI3L1)
pmid:25681350 p(MGI:"tumor necrosis factor") increases act(complex(GO:"NF-kappaB complex"))
pmid:25681350 p(MGI:"tumor necrosis factor") increases act(p(MGI:"avian reticuloendotheliosis viral (v-rel) oncogene related B"))
pmid:25681350 p(MGI:"tumor necrosis factor") increases act(complex(p(MGI:"avian reticuloendotheliosis viral (v-rel) oncogene related B"), p(MGI:"nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105")))
pmid:25681350 complex(p(MGI:"avian reticuloendotheliosis viral (v-rel) oncogene related B"), p(MGI:"nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105")) regulates p(MGI:"chitinase-like 1")
pmid:25681350 complex(p(MGI:"avian reticuloendotheliosis viral (v-rel) oncogene related B"), p(MGI:"nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105")) increases p(MGI:"chitinase-like 1")
pmid:25681350 complex(p(MGI:"avian reticuloendotheliosis viral (v-rel) oncogene related B"), p(MGI:"nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105")) increases complex(p(MGI:"avian reticuloendotheliosis viral (v-rel) oncogene related B"), p(MGI:"chitinase-like 1"), p(MGI:"nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105"))
pmid:25681350 complex(p(MGI:"avian reticuloendotheliosis viral (v-rel) oncogene related B"), p(MGI:"nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105")) increases complex(p(MGI:"avian reticuloendotheliosis viral (v-rel) oncogene related B"), p(MGI:"chitinase-like 1"), p(MGI:"nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105"))
pmid:21718217 r(HGNC:CHI3L1) positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:25681350 p(HGNC:OSM) causesNoChange r(HGNC:CHI3L1)
pmid:25681350 p(HGNC:OSM) causesNoChange r(HGNC:RELB)
pmid:25681350 p(HGNC:RELA) causesNoChange p(HGNC:CHI3L1)
pmid:21329555 p(HGNC:RELA) positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:25652642 p(HGNC:RELA) positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:21329555 p(HGNC:RELA) increases r(HGNC:BACE1)
pmid:21329555 p(HGNC:RELA) increases p(HGNC:BACE1)
pmid:21329555 p(HGNC:RELA) increases p(HBP:C99)
pmid:21329555 p(HGNC:RELA) causesNoChange p(HGNC:APP)
pmid:21329555 p(HGNC:RELA) increases a(CHEBI:"amyloid-beta")
pmid:28745240 p(HGNC:RELA) increases bp(MESH:"Synaptic Transmission")
pmid:28745240 p(HGNC:RELA) increases bp(GO:"long-term synaptic potentiation")
pmid:28745240 p(HGNC:RELA) negativeCorrelation bp(GO:"apoptotic process")
pmid:27288790 act(p(HGNC:RELA)) increases bp(GO:"apoptotic process")
pmid:27288790 p(HGNC:RELA) decreases bp(GO:"neuron apoptotic process")
pmid:25681350 p(HGNC:STAT3) causesNoChange p(HGNC:CHI3L1)
pmid:28745240 p(HGNC:STAT3) increases bp(GO:"astrocyte development")
pmid:19293145 act(p(HGNC:STAT3)) association p(HGNC:JAK2)
pmid:19293145 act(p(HGNC:STAT3)) association act(a(CHEBI:nicotine))
pmid:30116051 p(HGNC:STAT3) decreases bp(GO:macroautophagy)
pmid:25681350 path(MESH:Glioblastoma) increases p(MGI:"chitinase-like 1")
pmid:25681350 path(MESH:Glioblastoma) increases p(MGI:"avian reticuloendotheliosis viral (v-rel) oncogene related B")
pmid:25681350 composite(p(MGI:"interleukin 1 alpha"), p(MGI:"oncostatin M")) increases complex(p(MGI:"avian reticuloendotheliosis viral (v-rel) oncogene related B"), p(MGI:"chitinase-like 1"), p(MGI:"nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105"))
pmid:21329555 complex(g(HGNC:BACE1), p(FPLX:NFkappaB)) regulates r(HGNC:BACE1)
pmid:21329555 act(p(FPLX:NFkappaB), ma(tscript)) increases r(HGNC:BACE1)
pmid:29179999 act(p(FPLX:NFkappaB)) association bp(GO:"inflammatory response")
pmid:29179999 tloc(p(FPLX:NFkappaB), fromLoc(MESH:Cytosol), toLoc(MESH:"Cell Nucleus")) increases bp(GO:"inflammatory response")
pmid:27288790 p(FPLX:NFkappaB) regulates bp(GO:"inflammatory response")
pmid:29179999 p(FPLX:NFkappaB) positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:27288790 act(p(FPLX:NFkappaB)) positiveCorrelation path(MESH:"Alzheimer Disease")
pmid:29179999 act(p(FPLX:NFkappaB)) association path(HP:Neurodegeneration)
pmid:29179999 act(p(FPLX:NFkappaB)) regulates p(FPLX:"NADPH_oxidase")
pmid:29179999 act(p(FPLX:NFkappaB)) regulates p(HGNC:PTGS2)
pmid:27288790 p(FPLX:NFkappaB) regulates p(HGNC:PTGS2)
pmid:29179999 act(p(FPLX:NFkappaB)) regulates a(MESH:Interleukins)
pmid:29179999 act(p(FPLX:NFkappaB)) regulates p(FPLX:SOD)
pmid:29179999 act(p(FPLX:NFkappaB)) increases p(HGNC:BACE1)
pmid:27288790 p(FPLX:NFkappaB) association path(MESH:Inflammation)
pmid:27288790 p(FPLX:NFkappaB) association bp(GO:"negative regulation of neuron apoptotic process")
pmid:27288790 p(FPLX:NFkappaB) association bp(GO:"neuron differentiation")
pmid:27288790 p(FPLX:NFkappaB) association bp(GO:"apoptotic process")
pmid:27288790 p(FPLX:NFkappaB) association bp(MESH:"Neuronal Outgrowth")
pmid:27288790 p(FPLX:NFkappaB) association bp(GO:"regulation of synaptic plasticity")
pmid:27288790 act(p(FPLX:NFkappaB)) increases tloc(p(FPLX:NFkappaB), fromLoc(MESH:Cytosol), toLoc(MESH:"Cell Nucleus"))
pmid:27288790 act(p(FPLX:NFkappaB)) increases complex(a(MESH:DNA), p(FPLX:NFkappaB))
pmid:27288790 act(p(FPLX:NFkappaB)) increases p(HGNC:IL1B)
pmid:27288790 act(p(FPLX:NFkappaB)) increases p(HGNC:TNF)
pmid:27288790 act(p(FPLX:NFkappaB)) decreases p(HGNC:UCHL1)
pmid:27288790 p(FPLX:NFkappaB) regulates act(p(HGNC:NOS2))
pmid:27288790 act(p(FPLX:NFkappaB)) increases a(MESH:Cytokines)
pmid:27288790 act(p(FPLX:NFkappaB)) increases a(MESH:Chemokines)
pmid:27288790 p(FPLX:NFkappaB) increases m(MIRBASE:"hsa-mir-125b-1")
pmid:27288790 p(FPLX:NFkappaB) increases m(MIRBASE:"hsa-mir-125b-2")
pmid:27288790 p(FPLX:NFkappaB) increases m(MIRBASE:"hsa-mir-146a")
pmid:27288790 p(FPLX:NFkappaB) increases m(MIRBASE:"hsa-mir-155")
pmid:27288790 act(p(FPLX:NFkappaB), ma(tscript)) increases m(MIRBASE:"hsa-mir-155")
pmid:30640040 p(FPLX:NFkappaB) association a(PUBCHEM:5318517)
pmid:26118667 p(FPLX:NFkappaB) increases complex(g(MIRBASE:"rno-mir-195"), p(FPLX:NFkappaB))
pmid:21329555 complex(g(HGNC:BACE1), p(HGNC:RELA)) increases r(HGNC:BACE1)
pmid:21329555 p(HGNC:NFKBIA) decreases a(CHEBI:"amyloid-beta")
pmid:29179999 p(HGNC:NFKBIA) decreases act(p(FPLX:NFkappaB))
pmid:27288790 p(HGNC:NFKBIA) decreases act(p(FPLX:NFkappaB))
pmid:21329555 bp(GO:"NIK/NF-kappaB signaling") association path(MESH:Inflammation)
pmid:21329555 bp(GO:"NIK/NF-kappaB signaling") association path(MESH:"Oxidative Stress")
pmid:21329555 path(MESH:"Oxidative Stress") association bp(GO:"NIK/NF-kappaB signaling")
pmid:30012004 path(MESH:"Oxidative Stress") positiveCorrelation path(MESH:"Huntington Disease")
pmid:21329555 p(HGNC:TNF) increases bp(GO:"NIK/NF-kappaB signaling")
pmid:21329555 p(HGNC:TNF) increases r(HGNC:BACE1)
pmid:21329555 p(HGNC:TNF) increases r(HGNC:BACE1)